CNS Disorders  >>  memantine  >>  Phase 3
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12 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
memantine / Generic mfg.
NCT00624026 / 2006-003616-21: Memantine - Communication Study

Completed
3
107
Europe
Memantine-HCl
Merz Pharmaceuticals GmbH
Alzheimer's Disease
12/08
12/08
NCT00804271 / 2008-005144-16: Memantine and Validation of a New Alzheimer's Disease Scale

Completed
3
487
Europe
memantine, Axura
Merz Pharmaceuticals GmbH
Alzheimer's Disease
11/09
11/09
NCT00857649: Efficacy and Safety of Memantine in Moderate to Severe Alzheimer's Disease

Terminated
3
369
Canada
Memantine, Ebixa®, Placebo
H. Lundbeck A/S
Alzheimer's Disease
04/10
09/10
NCT00857233: Safety and Tolerability of Memantine in Moderate to Severe Alzheimer's Disease

Terminated
3
297
Canada
Memantine, Ebixa®
H. Lundbeck A/S
Alzheimer's Disease
07/10
10/10
NCT01074619: Study on Cognitive Disorders of Multiple Sclerosis

Completed
3
90
Europe
Memantine, Placebo
University Hospital, Caen, Ministry of Health, France, H. Lundbeck A/S
Multiple Sclerosis
03/11
11/11
NCT00594737: Open Label Pilot Study of the Effects of Memantine on FDG-PET in Frontotemporal Dementia

Completed
3
17
Canada
memantine hydrochloride, Ebixa, Namenda
Tiffany Chow, MD, H. Lundbeck A/S
Frontotemporal Dementia
06/12
06/12
2006-000860-10: An Open-Label Study Investigating the Specific Effects of Memantine in Institutionalised Patients with Alzheimer’s Disease

 
3
40
Europe
Ebixa, Lu 00-800, Ebixa 10 mg film-coated tablets, Ebixa 10 mg film-coated tablets
H. Lundbeck A/S
Effects of memantine treatment in institutionalised patients with Alzheimer\'s Disease.
 
09/06
STEADFAST, NCT02080364 / 2016-002005-19: Evaluation of the Efficacy and Safety of Azeliragon (TTP488) in Patients With Mild Alzheimer's Disease

Checkmark From post-hoc analyses of STEADFAST trial [screenshot]
Mar 2019 - Mar 2019: From post-hoc analyses of STEADFAST trial [screenshot]
Checkmark From STEADFAST trial at CTAD [screenshot]
Oct 2018 - Oct 2018: From STEADFAST trial at CTAD [screenshot]
Checkmark Efficacy results from Part B of STEADFAST study
More
Terminated
3
880
Europe, Canada, US, RoW
Azeliragon, TTP488, Placebo
vTv Therapeutics
Alzheimer's Disease
06/18
06/18
NCT01872598 / 2010-021218-50: Masitinib in Patients With Mild to Moderate Alzheimer's Disease

Completed
3
721
Europe, RoW
Masitinib, AB1010, Placebo, Placebo Oral Tablet, Standard of care
AB Science
Alzheimer Disease
12/20
12/20
MIND, NCT03986424: Local Study of Akatinol Memantine in VaD in Russia

Completed
3
130
RoW
Akatinol Memantine 20 mg, Akatinol Memantine 10 mg
Merz Pharmaceuticals GmbH, LLC Merz Pharma, Russia
Vascular Dementia
06/22
06/22
2021-002179-21: A phase 3 study to evaluate the safety and efficacy of masitinib as add-on therapy in patients with mild to moderate Alzheimer's disease treated with standard of care: cholinesterase inhibitors, memantine

Not yet recruiting
3
600
Europe
Masitinib, AB1010, Film-coated tablet
AB Science, ABScience, AB Science, ABScience
Alzheimer's disease, Diseases [C] - Nervous System Diseases [C10]
 
 
NCT00353665: Memantine for Disability in Amyotrophic Lateral Sclerosis (MEDALS)

Completed
2/3
63
Europe
Memantine (Ebixa), Ebixa, riluzole, rilutek, Placebo
University of Lisbon, H. Lundbeck A/S
Amyotrophic Lateral Sclerosis
06/08
01/09

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