memantine / Generic mfg.  >>  Phase 3
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29 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
memantine / Generic mfg.
ACTRN12621000175875: MEMOIR: a clinical trial of memantine and Graded Motor Imagery for Complex Regional Pain Syndrome

Recruiting
3
160
 
Neuroscience Research Australia, National Health and Medical Research Council
Complex Regional Pain Syndrome
 
 
2013-002055-15: CONTROLLED MULTICENTER STUDY ON THE MOOD-STABILIZING EFFECT OF MEMANTINE IN BIPOLAR I DISORDERS STUDIO MULTICENTRICO CONTROLLATO SULL'EFFETTO PROFILATTICO DELLA MEMANTINA NEL DISTURBO BIPOLARE DI TIPO I

Ongoing
3
106
Europe
Coated tablet, EBIXA, LAMOTRIGINE DOC -GENERIC
UNIVERSITY OF SASSARI, UNIVERSITY OF SASSARI
BIPOLAR I MOOD DISORDERS DISTURBO DELL'UMORE DI TIPO I, MANIC-DEPRESSIVE ILLNESS MALATTIA MANIACO-DEPRESSIVA, Psychiatry and Psychology [F] - Mental Disorders [F03]
 
 
2005-005859-18: EFFECT OF MEMANTINE TREATMENT ON BRAIN FUNCTION AND MORPHOLOGICAL STRUCTURE IN PATIENTS WITH MODERATE TO SEVERE PATIENTS WITH ALZHEIMER S DISEASE A STRUCTURAL MR AND FMRI STUDY

Ongoing
3
30
Europe
EBIXA*56CPR RIV 10MG, EBIXA*56CPR RIV 10MG
FONDAZIONE SANTA LUCIA
Moderate to severe Alzheimer s disease
 
 
2006-000860-10: An Open-Label Study Investigating the Specific Effects of Memantine in Institutionalised Patients with Alzheimer’s Disease

 
3
40
Europe
Ebixa, Lu 00-800, Ebixa 10 mg film-coated tablets, Ebixa 10 mg film-coated tablets
H. Lundbeck A/S
Effects of memantine treatment in institutionalised patients with Alzheimer\'s Disease.
 
09/06
2007-004297-40: Pharmacological treatment of nystagmus: A randomised double masked placebo controlled crossover study using gabapentin and memantine.

Ongoing
3
180
Europe
Memantine, Gabapentin, N/A, Neurontin, N/A, Neurontin
University Hospitals of Leicester NHS Trust
Nystagmus
 
 
2009-016751-22: A double blind, placebo controlled study of memantine in patients with obsessive-compulsive disorder.

Ongoing
3
50
Europe
memantine, Ebixa, Ebixa
AMC, divisie Psychiatrie
Obsessive-compulsive disorder (OCD)
 
 
2019-002778-30: Double-blind, randomised, multicenter study to evaluate the efficacy and safety of memantine in adolescents with Bipolar Disorder Studio multicentrico randomizzato in doppio cieco per valutare l'efficacia e la sicurezza della memantina negli adolescenti con Disturbo Bipolare

Not yet recruiting
3
68
Europe
MEMANTINA ACCORD, [NA], Film-coated tablet, MEMANTINA ACCORD - 10 MG - COMPRESSA RIVESTITA CON FILM - USO ORALE - BLISTER (PVC/PE/PVDC/ALLUMINIO) - 56 COMPRESSE
IRCCS, OSPEDALE PEDIATRICO BAMBINO GESÙ DI ROMA, Ministero della Salute
Bipolar Disorder Disturbo Bipolare, Bipolar Disorder in adolescents Disturbo bipolare negli adolescenti, Psychiatry and Psychology [F] - Mental Disorders [F03]
 
 
NCT03858270: Inhibition of α-synuclein Cell-cell Transmission by NMDAR Blocker, Memantine

Recruiting
3
50
US
Memantine, Namenda, Placebo
Wayne State University
Parkinson Disease
04/22
07/23
2021-002179-21: A phase 3 study to evaluate the safety and efficacy of masitinib as add-on therapy in patients with mild to moderate Alzheimer's disease treated with standard of care: cholinesterase inhibitors, memantine

Not yet recruiting
3
600
Europe
Masitinib, AB1010, Film-coated tablet
AB Science, ABScience, AB Science, ABScience
Alzheimer's disease, Diseases [C] - Nervous System Diseases [C10]
 
 
MemaROCD, NCT05015595: Memantine for Refractory OCD Patients

Not yet recruiting
3
20
NA
Memantine Oral Tablet, Placebo
University of Roma La Sapienza
Obsessive-Compulsive Disorder
10/22
12/22
NCT03550391: Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

Recruiting
3
206
Canada, US
Memantine, Hippocampal-avoidant (HA-WBRT) Radiotherapy, Stereotactic Radiosurgery (SRS)
Canadian Cancer Trials Group, Alliance for Clinical Trials in Oncology, NRG Oncology
Brain Metastases
06/27
12/27
NCT06337994: Memantine Hydrochloride for Treatment of Cognitive Dysfunction Due to Traumatic Brain Injury

Recruiting
3
100
RoW
Memantine Hydrochloride
Assiut University
Treatment of Posttraumatic Cognitive Dysfunction
06/24
12/24
MEMENTO, NCT06275035: Evaluation of Memantine in the Preservation of Memory and Neurocognition Following CSI

Recruiting
3
101
RoW
Memantine Oral Tablet, Memantine
Tata Memorial Centre
Neurocognitive Dysfunction
01/26
01/31
NCT03553875: Memantine for the Treatment of Social Deficits in Youth With Disorders of Impaired Social Interactions

Recruiting
3
100
US
Memantine Hydrochloride, Placebo
Massachusetts General Hospital
Autism, Autism Spectrum Disorder, Nonverbal Learning Disability
06/24
06/24
NRG-BN009, NCT04588246: Testing the Addition of Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in People With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery

Recruiting
3
350
US
Memantine, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration, Stereotactic Radiosurgery, Stereotactic External Beam Irradiation, stereotactic external-beam radiation therapy, Stereotactic Radiation Therapy, Stereotactic Radiotherapy, stereotaxic radiation therapy, stereotaxic radiosurgery, Whole-Brain Radiotherapy, WBRT, whole-brain radiation therapy
NRG Oncology, National Cancer Institute (NCI)
Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma, Metastatic Digestive System Carcinoma, Metastatic Lung Non-Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Brain, Metastatic Melanoma, Metastatic Renal Cell Carcinoma, Prognostic Stage IV Breast Cancer AJCC v8, Recurrent Brain Neoplasm, Stage IV Lung Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8
01/25
01/30
NRG-CC009, NCT04804644: Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

Recruiting
3
200
Canada, US
Memantine Hydrochloride, Ebixia, Namenda, Neurocognitive Assessment, Stereotactic Radiosurgery, Stereotactic External Beam Irradiation, stereotactic external-beam radiation therapy, Stereotactic Radiation Therapy, Stereotactic Radiotherapy, stereotaxic radiation therapy, stereotaxic radiosurgery, Whole-Brain Radiotherapy, WBRT, whole-brain radiation therapy
NRG Oncology, National Cancer Institute (NCI)
Metastatic Lung Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Brain, Recurrent Lung Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8
07/28
07/30
NCT04939597: A Study to See if Memantine Protects the Brain During Radiation Therapy Treatment for Primary Central Nervous System Tumors

Recruiting
3
192
US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Cognitive Assessment, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Memantine Hydrochloride, Ebixia, Namenda, Placebo Administration, Questionnaire Administration
Children's Oncology Group
Central Nervous System Carcinoma
09/27
09/27
ACTRN12607000181404: Efficacy of Memantine [N- Methyl- D- Aspartate (NMDA) receptor antagonist] versus placebo in acute non arteritic anterior ischemic optic neuropathy (NAION)

Active, not recruiting
2/3
44
 
Tehran University of Medical sciences, Ophthalmology department/ school of medicine/ Medical Sciences/ Tehran University
Non arteritic anterior ischemic optic neuropathy (NAION)
 
 
ACTRN12609000111279: The effects of memantine versus placebo on visual functions after scleral buckling for regmatogenous retinal detachment (RRD)

Active, not recruiting
2/3
60
 
Tehran University of Medical sciences, Ophthalmology department/ school of medicine/ Medical Sciences/ Tehran University
patients with rhegmatogenus retinal detachment undergoing scleral buckeling surgery
 
 
ACTRN12611000350921: The effects of memantine versus placebo on visual functions of patient with optic neuritis

Active, not recruiting
2/3
60
 
Tehran University of Medical sciences, Tehran University, Ophthalmology department/ School of medicine/ Medical Sciences
isolated optic neuritis, optic neuritis
 
 

Not yet recruiting
2/3
750
Europe
Memantine, Trazodone, Oral solution, Oral liquid, Trazodone Hydrochloride 100mg/5ml Oral Solution
University of Edinburgh, NHS Lothian, Euan MacDonald Centre, University of Edinburgh, MND Scotland, My Name'5 Doddie Foundation,
Motor Neurone Disease, Motor Neurone Disease, Diseases [C] - Nervous System Diseases [C10]
 
 
NCT04035798: add-on Low Dose Memantine in Middle-to-old Aged Bipolar II Disorder Patients

Recruiting
2/3
120
RoW
Memantine or placebo
National Cheng-Kung University Hospital, Ministry of Science and Technology, Taiwan
Bipolar II Disorder
07/21
07/22
NCT04737967: The Potential Protective Role of Venlafaxine Versus Memantine in Paclitaxel Induced Peripheral Neuropathy

Recruiting
2/3
60
RoW
Venlafaxine, Memantine
Mendel AI, Cairo University
Oncology Pain, Chemotherapy-induced Peripheral Neuropathy
08/21
10/21
NCT04857983: Memantine Augmentation of Targeted Cognitive Training in Schizophrenia

Recruiting
2/3
69
US
Memantine, targeted cognitive training (TCT), Placebo
University of California, San Diego
Schizophrenia, Schizoaffective Disorder
09/24
12/24
NCT05796752: Behavioral Treatment and Memantine in Body Focused Repetitive Behaviors

Recruiting
2/3
28
US
Memantine, Namenda, ComB Behavioral Therapy
University of Chicago
Skin-Picking, Trichotillomania (Hair-Pulling Disorder)
06/24
06/24
NCT04687566: Dextromethorphan, Memantine Monotherapy, or Combined Use of Dextromethorphan and Memantine in Amphetamine Addiction

Recruiting
2/3
120
RoW
Dextromethorphan, Memantine, Dextromethorphan and memantine, Placebo
National Cheng-Kung University Hospital, Ministry of Science and Technology, Taiwan
Amphetamine Addiction, Pharmacotherapy
07/24
07/24
NCT06007846: A Prospective Study of Memantine in Patients With Cirrhosis and Liver Cancer

Recruiting
2/3
12
US
Namenda, Memantine
Inova Health Care Services
Hepatocellular Carcinoma, Cirrhosis
08/24
08/25
NCT03342443: Effect of Memantine on Radiotherapy-related Cognitive Impairment

Recruiting
2/3
240
RoW
Memantine, Arm I, Placebo, Arm II
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Cognitive Impairment
10/24
12/24
MND-SMART, NCT04302870: Motor Neurone Disease - Systematic Multi-Arm Adaptive Randomised Trial

Recruiting
2/3
800
Europe
Memantine Hydrochloride Oral Solution, Trazodone Hydrochloride oral solution, Placebo oral solution, Amantadine Hydrochloride Oral Solution
University of Edinburgh, University College, London, University of Warwick, NHS Lothian
Motor Neuron Disease, Amyotrophic Lateral Sclerosis
09/26
12/26

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