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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
ALA sonodynamic therapy / INSIGHTEC, SonALAsense, Ivy Brain Tumor Center
NCT05123534: A Phase 2 Study of Sonodynamic Therapy Using SONALA-001 and Exablate 4000 Type 2.0 in Patients With DIPG	Recruiting	2	40	US	SONALA-001 (ALA) and MR-Guided Focused Ultrasound device (MRgFUS), Exablate Type 2.0	SonALAsense, Inc.	Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma	08/24	08/25
NCT05370508: A Study of Sonodynamic Therapy Using SONALA-001 and Exablate 4000 Type 2.0 in Subjects With Recurrent GBM	Active, not recruiting	1/2	8	US	SONALA-001 (ALA) and MR-Guided Focused Ultrasound device (MRgFUS), Exablate Type 2.0	SonALAsense, Inc.	Recurrent GBM	04/26	11/26
NCT04559685: Study of Sonodynamic Therapy in Participants With Recurrent High-Grade Glioma	Recruiting	1	30	US	SONALA-001(ALA) and MR-Guided Focused Ultrasound device (MRgFUS), MR-Guided Focused Ultrasound device (MRgFUS)	Nader Sanai, Barrow Neurological Institute, Ivy Brain Tumor Center, SonALAsense, Inc., InSightec	High Grade Glioma	12/24	03/25