- |||||||||| sirolimus / Generic mfg.
Journal: Genomic discovery of an evolutionarily programmed modality for small-molecule targeting of an intractable protein surface. (Pubmed Central) - Aug 18, 2020 The flat-targeting modality demonstrated here has the potential to expand the druggable target range of small-molecule therapeutics. As CEP250 was recently found to be an interaction partner with the Nsp13 protein of the SARS-CoV-2 virus that causes COVID-19 disease, it is possible that WDB002 or an analog may exert useful antiviral activity through its ability to form high-affinity ternary complexes containing CEP250 and FKBP12.
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