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LML134
/
Novartis
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LML134
/
Novartis
Clinical, Journal:
The discovery of LML134, a histamine H3 receptor inverse agonist for the clinical treatment of excessive sleep disorders.
(Pubmed Central) - Apr 10, 2020
No abstract available
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LML134
/
Novartis
Trial termination:
A Study to Assess the Wakefulness Promoting Effect, Safety, Tolerability, and Pharmacokinetics (PK) of LML134 in Shift Work Disorder
(clinicaltrials.gov) - Feb 16, 2019
P2
, N=24, Terminated,
Sponsor: Novartis Pharmaceuticals
No abstract available Completed --> Terminated; CLML134X2201 was terminated due to business reasons and not to safety findings
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LML134
/
Novartis
Trial completion, Enrollment change:
A Study to Assess the Wakefulness Promoting Effect, Safety, Tolerability, and Pharmacokinetics (PK) of LML134 in Shift Work Disorder
(clinicaltrials.gov) - Oct 2, 2018
P2
, N=24, Completed,
Sponsor: Novartis Pharmaceuticals
Completed --> Terminated; CLML134X2201 was terminated due to business reasons and not to safety findings Recruiting --> Completed | N=46 --> 24
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LML134
/
Novartis
Trial completion date, Trial primary completion date:
A Study to Assess the Wakefulness Promoting Effect, Safety, Tolerability, and Pharmacokinetics (PK) of LML134 in Shift Work Disorder
(clinicaltrials.gov) - Aug 23, 2018
P2
, N=46, Recruiting,
Sponsor: Novartis Pharmaceuticals
Recruiting --> Completed | N=46 --> 24 Trial completion date: Nov 2019 --> Sep 2018 | Trial primary completion date: Nov 2019 --> Sep 2018
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LML134
/
Novartis
Trial completion date, Trial primary completion date:
A Study to Assess the Wakefulness Promoting Effect, Safety, Tolerability, and Pharmacokinetics (PK) of LML134 in Shift Work Disorder
(clinicaltrials.gov) - Jun 14, 2018
P2
, N=46, Recruiting,
Sponsor: Novartis Pharmaceuticals
Trial completion date: Nov 2019 --> Sep 2018 | Trial primary completion date: Nov 2019 --> Sep 2018 Trial completion date: Jun 2018 --> Nov 2019 | Trial primary completion date: Jun 2018 --> Nov 2019
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LML134
/
Novartis
Enrollment open:
A Study to Assess the Wakefulness Promoting Effect, Safety, Tolerability, and Pharmacokinetics (PK) of LML134 in Shift Work Disorder
(clinicaltrials.gov) - Jul 24, 2017
P2
, N=46, Recruiting,
Sponsor: Novartis Pharmaceuticals
Trial completion date: Jun 2018 --> Nov 2019 | Trial primary completion date: Jun 2018 --> Nov 2019 Not yet recruiting --> Recruiting
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LML134
/
Novartis
New P2 trial:
A Study to Assess the Wakefulness Promoting Effect, Safety, Tolerability, and Pharmacokinetics (PK) of LML134 in Shift Work Disorder
(clinicaltrials.gov) - May 4, 2017
P2
, N=46, Not yet recruiting,
Sponsor: Novartis Pharmaceuticals
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LML134
/
Novartis
Trial completion:
First-in-human Study to Assess the Safety and Pharmacokinetics of LML134 in Healthy Volunteers
(clinicaltrials.gov) - Apr 26, 2016
P1
, N=133, Completed,
Sponsor: Novartis Pharmaceuticals
Not yet recruiting --> Recruiting Recruiting --> Completed
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LML134
/
Novartis
Enrollment open:
First-in-human Study to Assess the Safety and Pharmacokinetics of LML134 in Healthy Volunteers
(clinicaltrials.gov) - Jun 1, 2015
P1
, N=152, Recruiting,
Sponsor: Novartis Pharmaceuticals
Recruiting --> Completed Not yet recruiting --> Recruiting
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LML134
/
Novartis
Trial primary completion date:
First-in-human Study to Assess the Safety and Pharmacokinetics of LML134 in Healthy Volunteers
(clinicaltrials.gov) - Feb 11, 2015
P1
, N=152, Not yet recruiting,
Sponsor: Novartis Pharmaceuticals
Not yet recruiting --> Recruiting Trial primary completion date: Sep 2015 --> Dec 2015
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LML134
/
Novartis
New P1 trial:
First-in-human Study to Assess the Safety and Pharmacokinetics of LML134 in Healthy Volunteers
(clinicaltrials.gov) - Jan 8, 2015
P1
, N=152, Not yet recruiting,
Sponsor: Novartis Pharmaceuticals