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Journal: Development and Validation of Diagnostic KASP Markers for Brown Planthopper Resistance in Rice. (Pubmed Central) - Jul 30, 2022 These identified genotypes could be useful as donors for transferring BPH resistance into popular varieties with marker-assisted selection using these diagnostic SNPs. The resistant lines and the significant SNPs unearthed from our study can be useful in developing BPH-resistant varieties after validating them in biparental populations with the potential usefulness of SNPs as causal markers.
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Journal: Genetic insights into the paternal admixture history of Chinese Mongolians via high-resolution customized Y-SNP SNaPshot panels. (Pubmed Central) - Nov 29, 2021 Genetic clustering analyses indicated that the studied Mongolians showed close genetic affinities with other Altaic-speaking populations and Sinitic-speaking Hui people. The Y-SNP haplotype/haplogroup-based genetic legacy not only revealed that the stratification among geographically/linguistically/ethnically different Chinese populations was highly consistent with the geographical division and language classification, but also demonstrated that patrilineal genetic materials could provide fine-scale genetic structures among geographically different Mongolian people, suggesting that our developed high-resolution Y-SNP SNaPshot panels have the potential for forensic pedigree searches and biogeographical ancestry inference.
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Journal: Title: Developmental validation of Y-SNP pedigree tagging system: A panel via quick ARMS PCR. (Pubmed Central) - Mar 23, 2021 The panel precisely defines the 11 haplogroups (E-M96, D-JST021355, N-M231, C-M130, O-P186, I-M170, IJ-M429, K-M9, QR-M45, G-M201, and IJK-M522) and 13 sub-haplogroups (D1a1a1-N1, D1a2a-P47, C2-M217, N1a1-M46, O1a-M119, O1b-M268, O1b2-M176, O2-M122, O2a1-KL1, O2a2-P201, O2a2b-P164, O2a2a1a2-M7 and O2a2b1a1-M117)...In this study, we try to discriminate the suspect's pedigree on the level of Y-SNP haplogroups. These results show that Y-SNP Pedigree Tagging System is a robust and reliable amplification kit which can be used for male haplogroup determination.
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Enrollment change, Trial completion date, Trial termination, Trial primary completion date: ABI-M201 in Adult Subjects With Mildly-to-Moderately Active Ulcerative Colitis (clinicaltrials.gov) - Mar 19, 2021 P1b, N=15, Terminated, These results show that Y-SNP Pedigree Tagging System is a robust and reliable amplification kit which can be used for male haplogroup determination. N=44 --> 15 | Trial completion date: Mar 2023 --> Jan 2021 | Recruiting --> Terminated | Trial primary completion date: Aug 2022 --> Jan 2021; Sponsor Decision
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Trial completion date, Trial primary completion date: ABI-M201 in Adult Subjects With Mildly-to-Moderately Active Ulcerative Colitis (clinicaltrials.gov) - Oct 7, 2020 P1b, N=44, Recruiting, N=44 --> 15 | Trial completion date: Mar 2023 --> Jan 2021 | Recruiting --> Terminated | Trial primary completion date: Aug 2022 --> Jan 2021; Sponsor Decision Trial completion date: Dec 2021 --> Mar 2023 | Trial primary completion date: Jun 2021 --> Aug 2022
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