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Journal: Optimization of Chitosan-Decorated Solid Lipid Nanoparticles for Improved Flurbiprofen Transdermal Delivery. (Pubmed Central) - Jun 12, 2023 Also, the total permeation of chitosan-coated SLNs (F7-F9) was significantly higher than that of the noncoated formulation (F5). Overall, this study has successfully designed a suitable carrier system of chitosan-coated SLNs that provide insight into the current conventional therapeutic approaches and suggest new directions for the advancements in transdermal drug delivery systems for improved permeation of flurbiprofen.
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Journal: Flurbiprofen-loaded ethanolic liposome particles for biomedical applications. (Pubmed Central) - Jun 5, 2020 In stability study, optimized formulation showed maximum stability at 4 °C. These results suggest that transdermal system mediated application of flurbiprofen loaded ethanolic liposome can be considered as an effective way to afford consistent and predictable release of flurbiprofen which could provide beneficial effects in the management of various inflammatory diseases.
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Preclinical, Journal: Flurbiprofen loaded ethosomes - transdermal delivery of anti-inflammatory effect in rat model. (Pubmed Central) - Dec 20, 2019 These results suggest that transdermal system mediated application of flurbiprofen loaded ethanolic liposome can be considered as an effective way to afford consistent and predictable release of flurbiprofen which could provide beneficial effects in the management of various inflammatory diseases. The overall study concluded that this ethosomal approach offers a new delivery system for sustained and targeted delivery for flurbiprofen.
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