MaaT013 / MaaT Pharma 
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  • ||||||||||  MaaT013 / MaaT Pharma
    Enrollment open, Trial completion date, Trial primary completion date:  ARES: MaaT013 as Salvage Therapy in Ruxolitinib Refractory GI-aGVHD Patients (clinicaltrials.gov) -  Jun 24, 2022   
    P3,  N=75, Recruiting, 
    A Phase 3 trial is currently ongoing to confirm these results in ruxolitinib-refractory patients (NCT04769895). Not yet recruiting --> Recruiting | Trial completion date: Mar 2024 --> Sep 2024 | Trial primary completion date: May 2023 --> Sep 2023
  • ||||||||||  MaaT013 / MaaT Pharma
    Enrollment open, Trial completion date, Trial primary completion date:  ORION: Prospective Interventional Study Exploring the Microbiota Recolonization in SR-GvHD Patients Receiving MaaT013 (clinicaltrials.gov) -  Jun 24, 2022   
    P=N/A,  N=40, Recruiting, 
    Not yet recruiting --> Recruiting | Trial completion date: Mar 2024 --> Sep 2024 | Trial primary completion date: May 2023 --> Sep 2023 Not yet recruiting --> Recruiting | Trial completion date: Jan 2023 --> Mar 2024 | Trial primary completion date: Aug 2022 --> Aug 2023
  • ||||||||||  MaaT013 / MaaT Pharma
    Enrollment closed, Trial completion date, Trial primary completion date:  HERACLES: Treatment of Steroid Refractory Gastro-intestinal Acute GVHD afteR AllogeneiC HSCT With fEcal Microbiota tranSfer (clinicaltrials.gov) -  May 21, 2020   
    P2,  N=32, Active, not recruiting, 
    The overall response rate was 82% with the off-the-shelf MaaT013 product, shown to be safe and effective in these immunocompromised patients with severe conditions, warranting further exploration of the full ecosystem microbiota restoration approach. Recruiting --> Active, not recruiting | Trial completion date: Sep 2020 --> Dec 2020 | Trial primary completion date: Sep 2019 --> Jan 2020