SC-006 / AbbVie 
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  • ||||||||||  SC-006 / AbbVie, SC-002 / AbbVie, tamrintamab pamozirine (SC-003) / AbbVie
    Journal:  Molecular Characterization of Clostridium botulinum Isolates from Sichuan Province, China (1990-2024). (Pubmed Central) -  Aug 6, 2025   
    In addition, analysis of BoNTs subtypes demonstrated that the types of BoNTs causing botulism in Sichuan were mainly types A, B, and E. Among them, some rare subtypes of BoNT reported for the first time in China, such as BoNT/B4, BoNT/E12, and BoNT/A5(B3), and no specific subtypes were predominant in the botulism incidents. This study is critical for disease surveillance and early warning systems, while also providing a basis for food safety regulation, clinical diagnosis, and treatment in the future.
  • ||||||||||  SC-006 / AbbVie, budigalimab (ABBV-181) / AbbVie
    Trial termination, Combination therapy, Metastases:  A Study of SC-006 and in Combination With ABBV-181 in Subjects With Advanced Colorectal Cancer (clinicaltrials.gov) -  Apr 29, 2019   
    P1,  N=29, Terminated, 
    SC-006 dose escalation was limited by thrombocytopenia observed below the predicted efficacious dose, leading to study termination. Completed --> Terminated; Strategic considerations
  • ||||||||||  SC-006 / AbbVie, budigalimab (ABBV-181) / AbbVie
    Trial completion, Trial completion date, Trial primary completion date, Combination therapy, Metastases:  A Study of SC-006 and in Combination With ABBV-181 in Subjects With Advanced Colorectal Cancer (clinicaltrials.gov) -  Apr 9, 2019   
    P1,  N=29, Completed, 
    Completed --> Terminated; Strategic considerations Active, not recruiting --> Completed | Trial completion date: Dec 2020 --> Mar 2019 | Trial primary completion date: Jul 2020 --> Mar 2019
  • ||||||||||  SC-006 / AbbVie, budigalimab (ABBV-181) / AbbVie
    Enrollment closed, Enrollment change, Combination therapy, Metastases:  A Study of SC-006 and in Combination With ABBV-181 in Subjects With Advanced Colorectal Cancer (clinicaltrials.gov) -  Jan 29, 2019   
    P1,  N=29, Active, not recruiting, 
    Active, not recruiting --> Completed | Trial completion date: Dec 2020 --> Mar 2019 | Trial primary completion date: Jul 2020 --> Mar 2019 Recruiting --> Active, not recruiting | N=108 --> 29