escitalopram / Generic mfg. 
Welcome,         Profile    Billing    Logout  
 0 Diseases   144 Trials   144 Trials   2302 News 


12345678910111213...5051»
  • ||||||||||  aripiprazole / Generic mfg., escitalopram / Generic mfg., clozapine / Generic mfg.
    Review, Journal:  Dual Atypical Antipsychotics in Treatment-Resistant Schizophrenia: A Correctional Case Report and Review of Literature. (Pubmed Central) -  Jun 21, 2024   
    In this article, we present a putative case where we believe that a combination regimen of paliperidone palmitate, oral aripiprazole, and escitalopram led to a notable mitigation of both positive and negative symptoms of psychosis in the case of an incarcerated patient with TRS, as well as an improvement in functional stability, which was conducive to housing in a less restrictive setting. A brief review of the published literature follows the report.
  • ||||||||||  Review, Journal:  Selective Serotonin Reuptake Inhibitors and Symptoms of Depression in Patients on Chronic Hemodialysis: A Systematic Review. (Pubmed Central) -  Jun 19, 2024   
    In one study, citalopram and psychological interventions were both effective in reducing the symptoms of depression and anxiety and, in another study, sertraline was modestly more effective than CBT at 12 weeks in reducing the symptoms of depression...SSRI administration, at the dosage used in the studies included in the present systematic review, seems safe in most hemodialysis patients. However, the paucity of studies and the limited number of patients included in the trials may suggest that further randomized, controlled studies are needed to determine if SSRIs may be used routinely in daily clinical practice in such a population.
  • ||||||||||  Clopixol (zuclopenthixol) / Lundbeck
    Journal:  Genetic diversity of cytochrome P450 in patients receiving psychiatric care in Greece: a step towards clinical implementation. (Pubmed Central) -  Jun 17, 2024   
    However, the paucity of studies and the limited number of patients included in the trials may suggest that further randomized, controlled studies are needed to determine if SSRIs may be used routinely in daily clinical practice in such a population. Dosage adjustment need was estimated for 10.2% of venlafaxine, 10.0% of paroxetine, 6.4% of sertraline, 30.8% of citalopram, 52.1% of escitalopram, 18.2% of fluvoxamine, 54.1% of tricyclic antidepressants, 16.7% of zuclopenthixol, 10.6% of haloperidol
  • ||||||||||  escitalopram / Generic mfg.
    Biomarker, Journal, Machine learning:  Mining key circadian biomarkers for major depressive disorder by integrating bioinformatics and machine learning. (Pubmed Central) -  Jun 14, 2024   
    This study revealed discovered 4 key circadian rhythm genes closely associated with MDD, which may serve as diagnostic biomarkers and therapeutic targets. The findings highlight the important roles of circadian disruptions in the pathogenesis of MDD, providing new insights for precision diagnosis and targeted treatment of MDD.
  • ||||||||||  Journal:  Evening chronotypes with depression report poorer outcomes of SSRIs: A survey-based study of self-ratings. (Pubmed Central) -  Jun 12, 2024   
    Vortioxetine presents as a promising therapeutic alternative that is worth considering for patients with escitalopram-induced jitteriness/anxiety syndrome. The idea that variation in circadian factors influences response to antidepressants was supported and encourages exploration of circadian mechanisms of depressive disorders and antidepressant treatments.
  • ||||||||||  escitalopram / Generic mfg.
    Journal:  Modulation of serotonin transporter expression by escitalopram under inflammation. (Pubmed Central) -  Jun 9, 2024   
    We show escitalopram's chemical efficacy is diminished under inflammation. Our model thus offers mechanisms for how chronic escitalopram affects brain serotonin, emphasizing the importance of optimized dose and time for future antidepressant discoveries.
  • ||||||||||  escitalopram / Generic mfg.
    Journal:  Large Individual Differences in Functional Connectivity in the Context of Major Depression and Antidepressant Pharmacotherapy. (Pubmed Central) -  Jun 8, 2024   
    Functional MRI data from 107 participants (63 female, 44 male) were collected at baseline, 2, and 8?weeks during which patients received pharmacotherapy (escitalopram, N?=?68) and controls (N?=?39) received no intervention...Only ?5% could be attributed to group differences. Our results suggest that examining individual differences, and their potential clinical relevance, alongside group differences may bring us closer to improving clinical outcomes for major depression.
  • ||||||||||  escitalopram / Generic mfg.
    Journal:  Individual differences in the boldness of female zebrafish are associated with alterations in serotonin function. (Pubmed Central) -  Jun 6, 2024   
    We found that escitalopram had opposing effects on thigmotaxis in bold and shy female animals: the drug caused bold fish to spend more time near the center of the tank and shy fish spent more time near the periphery. Taken together, our findings indicate that variation in serotonergic function has sex-specific contributions to individual differences in risk taking behavior.
  • ||||||||||  escitalopram / Generic mfg.
    Journal:  Elucidation of escitalopram oxalate and related antidepressants as putative inhibitors of PTP4A3/PRL-3 protein in hepatocellular carcinoma: A multi-computational investigation. (Pubmed Central) -  May 26, 2024   
    Therefore, in the current communication, an in-silico drug repurposing approach has been employed to target the function of PTP4A3/PRL-3 protein in HCC using antidepressants: Fluoxetine hydrochloride, Citalopram, Amitriptyline, Imipramine, and Escitalopram oxalate as the desired ligands...Escitalopram oxalate exhibited a comparatively significant docking score (-7.4?kcal/mol) compared to the control JMS-053 (-6.8?kcal/mol) against the PRL-3 protein...The docked complexes were subjected to MD studies (100?ns) showing stable interactions. Considering all the findings, it can be concluded that Escitalopram oxalate and related therapeutics can act as potential pharmacological candidates for targeting the activity of PTP4A3/PRL-3 in HCC.
  • ||||||||||  clomipramine / Generic mfg., risperidone / Generic mfg., escitalopram / Generic mfg.
    Journal:  The anti-inflammatory effects of antidepressants on colitis. (Pubmed Central) -  May 13, 2024   
    Clomipramine showed the best anti-inflammatory effect compared to Escitalopram and Risperidone. Therefore, clomipramine showed the best relieving effect on inflammation of ulcerative colitis in rats.
  • ||||||||||  Prolia (denosumab) / Amgen
    Denosumab-Induced Severe Hypocalcemia with Recurrent Side Effects (Poster Hall, Exhibit Hall A, Level 2) -  May 6, 2024 - Abstract #ATC2024ATC_1652;    
    Denosumab-induced hypocalcemia is rare, but due to its severe effects on neuromuscular and cardiac function, patients should be counseled on the symptoms of hypocalcemia to ensure prompt medical evaluation. Ultimately, treatment for post-LTx osteoporosis should be individualized with consideration of specific medical history as well as routine monitoring of calcium levels when prescribed denosumab.
  • ||||||||||  aspirin / Generic mfg., escitalopram / Generic mfg., apixaban / Generic mfg.
    Journal:  Top 4 Research Studies of the month for Italian Primary Care Physicians: April 2024. (Pubmed Central) -  May 6, 2024   
    Trialists found that there was approximately 1 fewer ischemic stroke and 1 more major bleed for every 250 persons treated with apixaban instead of aspirin, but in people treated with apixaban major bleeding was also significantly more likely...3) In an intriguing but somewhat limited network meta-analysis, probiotics were equally or more effective than treatment with any antidepressant except escitalopram...Instead, they are associated with concerning risks of harm, most notably cerebral hemorrhage identified on imaging studies. The balance of risk versus benefit demonstrated thus far doesn't justify the use of these costly (over US$ 20,000 annually) drugs.
  • ||||||||||  Journal:  A case of Pitt-Hopkins syndrome: psychopharmacological approach for anxiety, insomnia, and agitation. (Pubmed Central) -  May 3, 2024   
    After admission to our hospital, aripiprazole and hydroxyzine were prescribed for anxiety and ASD-related irritability...Hydroxyzine was stopped, and quetiapine was given to eliminate sleep disturbance...For the anxiety symptoms, escitalopram was prescribed...Patients with genetic syndromes may have various psychiatric complaints. Psychopharmacological interventions should be administered carefully for the side effects.
  • ||||||||||  escitalopram / Generic mfg.
    Journal:  Prescription and Dispensation of QT-Prolonging Medications in Individuals Receiving Hemodialysis. (Pubmed Central) -  Apr 30, 2024   
    Approximately 80% (from 78.6% for odansetron to 93.9% for escitalopram) of study drug new-use prescriptions occurred outside of an acute care event...Prescriptions for potentially interacting medications often originated from different prescribers. Strategies aimed at minimizing high-risk medication-prescribing practices in the population undergoing dialysis are needed.
  • ||||||||||  Retrospective data, Review:  Chinese herbal medicines for the treatment of depression: a systematic review and network meta-analysis. (Pubmed Central) -  Apr 18, 2024   
    Interestingly, commonly used synthetic drugs such as Fluoxetine, Escitalopram, Amitriptyline, Sertraline, Flupentixol and Melitracen, and Venlafaxine, not only appeared to be less effective than specific Chinese herbal medicines (Gan Mai Da Zao Decoction, Chaihu Jia Longgu Muli Decoction, Chai Hu Shu Gan San, Danzhi-Xiaoyao-San, and Xingnao Jieyu Decoction), but they were also related to substantially higher risk of adverse events...However, it underscores the necessity for larger, methodologically robust trials to further validate and refine these preliminary findings. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/, identifier CRD42023452109.
  • ||||||||||  escitalopram / Generic mfg.
    CLAUDIN-5 and Blood-Brain Barrier Integrity in Prefrontal Cortex in Suicide (Griffin Hall) -  Apr 14, 2024 - Abstract #SOBP2024SOBP_747;    
    High CLAUDIN-5 and ALBUMIN levels could serve as biomarkers for suicide risk. Future in vitro assessments should evaluate novel therapeutics promoting CLAUDIN-5 expression for suicide prevention.
  • ||||||||||  agomelatine / Generic mfg.
    Open Trial Agomelatine Treatment in Elderly MDD Patients With SSRI-Induced Hyponatremia (Griffin Hall) -  Apr 14, 2024 - Abstract #SOBP2024SOBP_50;    
    Our open trial study suggests that agomelatine may be a safe and effective treatment option for elderly patients suffering from major depressive disorder and SSRI-induced hyponatremia. Further research involving larger patient samples is required to validate our findings.
  • ||||||||||  paroxetine / Generic mfg., fluoxetine / Generic mfg., escitalopram / Generic mfg.
    Retrospective data, Journal:  Evaluating the Use of Selective Serotonin Reuptake Inhibitors (SSRIs) and Male Infertility: A Critical Retrospective Study. (Pubmed Central) -  Apr 13, 2024   
    Regarding the sperm analysis and the use of SSRIs, the impact of SSRIs use showed no significant differences in sperm liquefaction (p = 0.1), motility (p = 0.17), viscosity (p = 0.16), or count (p = 0.069) with escitalopram, fluoxetine, or paroxetine use; Our study showed no significant difference in the sperm analysis between the SSRI and non-SSRI cohorts. However, the relationship between SSRI use and sperm count warrants further investigation and consideration in clinical practice.