- |||||||||| doxycycline / generics
Journal: Effect of zinc on the collagen degradation in acid-etched dentin. (Pubmed Central) - Mar 22, 2019
...The demineralized ground dentin was incubated in six different media: artificial saliva (AS); 5Â mg/ml doxycycline in AS; 3.33, 6.82, 13.63, and 27.26Â mg/ml of zinc chloride (Zn) in AS...However, in subgroups with exogenous MMP, the inhibitory effect of zinc on collagen degradation did not depend on zinc concentration. All Zn groups for the four concentrations tested exhibited statistically significant inhibitory effect on collagen degradation.
- |||||||||| ciprofloxacin / generics, vancomycin / generics, doxycycline / generics
Journal: Poultry as a vector for emerging multidrug resistant Enterococcus spp.: First report of vancomycin (van) and the chloramphenicol-florfenicol (cat-fex-cfr) resistance genes from pigeon and duck faeces. (Pubmed Central) - Mar 21, 2019
Interestengly, fexA 11.9% (15/106), fexB 8.7% (11/106), vanA 18.9% (20/106), vanB 25.5% (27/106), and vanC 33% (35/106) genes were also determined in our study. The present study highlights the emergence of a linezolid sensitive-vancomycin resistant enterococci, which lacks the cfr gene reporting also for the first time the detection of van, fex and cat -genes in Enterococcus species recovered from chickens, ducks and pigeons in Egypt suggesting that poultry species could be potential vectors for transmission of multidrug resistant enterococci posing a public health risk.
- |||||||||| doxycycline / Generic mfg., adapalene/benzoyl peroxide / Generic mfg.
Trial completion: The Use of Oracea and Epiduo Forte in Severe Acne Patients (clinicaltrials.gov) - Mar 20, 2019
P4, N=22, Completed,
The present study highlights the emergence of a linezolid sensitive-vancomycin resistant enterococci, which lacks the cfr gene reporting also for the first time the detection of van, fex and cat -genes in Enterococcus species recovered from chickens, ducks and pigeons in Egypt suggesting that poultry species could be potential vectors for transmission of multidrug resistant enterococci posing a public health risk. Active, not recruiting --> Completed
- |||||||||| doxycycline / Generic mfg.
Trial completion date, Trial primary completion date: Intra-articular Doxycycline: A Novel Treatment of Adhesive Capsulitis (clinicaltrials.gov) - Feb 26, 2019
P4, N=40, Recruiting,
Initiation date: Jun 2018 --> Nov 2018 Trial completion date: Jun 2019 --> Jun 2021 | Trial primary completion date: Jan 2019 --> Jan 2020
- |||||||||| ceftriaxone / Generic mfg., doxycycline / Generic mfg.
Enrollment change, Trial completion date, Trial primary completion date: Study of Lyme Neuroborreliosis (clinicaltrials.gov) - Jan 16, 2019
P4, N=210, Completed,
Not yet recruiting --> Recruiting N=150 --> 210 | Trial completion date: May 2016 --> Dec 2018 | Trial primary completion date: May 2016 --> Dec 2017
- |||||||||| doxycycline / Generic mfg.
Trial completion, Trial completion date: Topical NanoDox® for Atopic Dermatitis (clinicaltrials.gov) - Dec 28, 2018
P2, N=15, Completed,
N=150 --> 210 | Trial completion date: May 2016 --> Dec 2018 | Trial primary completion date: May 2016 --> Dec 2017 Recruiting --> Completed | Trial completion date: Dec 2019 --> Nov 2018
- |||||||||| metformin / Generic mfg., doxycycline / Generic mfg.
Enrollment closed, Enrollment change, Trial primary completion date, Surgery: Metformin Hydrochloride and Doxycycline in Treating Patients With Head and Neck Squamous Cell Carcinoma That Can Be Removed by Surgery (clinicaltrials.gov) - Dec 24, 2018
P2, N=7, Active, not recruiting,
Recruiting --> Completed | Trial completion date: Dec 2019 --> Nov 2018 Recruiting --> Active, not recruiting | N=72 --> 7 | Trial primary completion date: Aug 2019 --> Dec 2018
- |||||||||| doxycycline / Generic mfg.
Trial primary completion date, Head-to-Head: Six Versus Two Weeks Treatment With Doxycycline in Lyme Neuroborreliosis (clinicaltrials.gov) - Dec 20, 2018
P3, N=250, Enrolling by invitation,
Recruiting --> Active, not recruiting | N=72 --> 7 | Trial primary completion date: Aug 2019 --> Dec 2018 Trial primary completion date: Sep 2019 --> Dec 2019
- |||||||||| doxycycline / Generic mfg.
Trial completion date, Trial primary completion date: Lipidome and Microbiome Profile of the Eye in Rosacea (clinicaltrials.gov) - Nov 26, 2018
P1, N=30, Recruiting,
Terminated --> Withdrawn Trial completion date: Nov 2018 --> Sep 2019 | Trial primary completion date: Nov 2018 --> Sep 2019
- |||||||||| Rituxan (rituximab) / Biogen, Zenyaku Kogyo, Roche
Journal: Perspective From the 5th International Pemphigus and Pemphigoid Foundation Scientific Conference. (Pubmed Central) - Nov 24, 2018
Scientific sessions covered recent, ongoing, and future clinical trials in pemphigus and bullous pemphigoid, disease activity and quality of life instruments, and the IPPF Natural History Study. Furthermore, the meeting provided an opportunity to hear firsthand from patients, investigators, and industry about their experience enrolling for clinical trials.
- |||||||||| doxycycline / Generic mfg., adapalene/benzoyl peroxide / Generic mfg.
Enrollment closed, Trial completion date, Trial primary completion date: The Use of Oracea and Epiduo Forte in Severe Acne Patients (clinicaltrials.gov) - Nov 2, 2018
P4, N=22, Active, not recruiting,
Furthermore, the meeting provided an opportunity to hear firsthand from patients, investigators, and industry about their experience enrolling for clinical trials. Recruiting --> Active, not recruiting | Trial completion date: Sep 2018 --> Jan 2019 | Trial primary completion date: Sep 2018 --> Dec 2018
- |||||||||| cephalexin / Generic mfg., trimethoprim/sulfamethoxazole / Generic mfg., doxycycline / Generic mfg.
Trial completion date, Trial primary completion date: Effects of Treatments on Atopic Dermatitis (clinicaltrials.gov) - Oct 29, 2018
P2, N=130, Recruiting,
Recruiting --> Active, not recruiting | Trial completion date: Sep 2018 --> Jan 2019 | Trial primary completion date: Sep 2018 --> Dec 2018 Trial completion date: Jun 2019 --> Jun 2020 | Trial primary completion date: Jun 2019 --> Jun 2020
- |||||||||| doxycycline / Generic mfg.
Trial completion date, Trial primary completion date: KL2TR001438: Doxycycline to Upgrade Organ Response in Light Chain (AL) Amyloidosis Trial (clinicaltrials.gov) - Oct 17, 2018
P2, N=31, Active, not recruiting,
Trial completion date: Dec 2018 --> Dec 2020 | Trial primary completion date: Dec 2018 --> Dec 2020 Trial completion date: Sep 2019 --> Sep 2020 | Trial primary completion date: Sep 2018 --> Sep 2019
- |||||||||| doxycycline / Generic mfg., granisetron oral / Generic mfg., paracetamol / Generic mfg.
Trial completion date, Trial primary completion date: TBE-LB2014: Tick-borne Encephalitis and Positive Borrelial Antibodies (clinicaltrials.gov) - Oct 16, 2018
P=N/A, N=100, Recruiting,
Trial completion date: Sep 2019 --> Sep 2020 | Trial primary completion date: Sep 2018 --> Sep 2019 Trial completion date: Sep 2019 --> Sep 2020 | Trial primary completion date: Sep 2018 --> Sep 2020
- |||||||||| doxycycline / Generic mfg.
Trial initiation date: Doxycycline to Protect Heart Muscle After Heart Attacks (clinicaltrials.gov) - Oct 16, 2018
P2, N=170, Not yet recruiting,
Trial completion date: Sep 2019 --> Sep 2020 | Trial primary completion date: Sep 2018 --> Sep 2020 Initiation date: Jul 2018 --> Dec 2018
- |||||||||| doxycycline / Generic mfg.
Trial completion, Trial completion date: Evaluation of Local Doxycycline in Smokers With Chronic Periodontitis (clinicaltrials.gov) - Oct 11, 2018
P2, N=40, Completed,
Trial completion date: Oct 2018 --> Oct 2019 | Trial primary completion date: Oct 2018 --> Oct 2019 Active, not recruiting --> Completed | Trial completion date: Mar 2018 --> Mar 2017
- |||||||||| doxycycline / Generic mfg.
Trial completion date: Doxycycline for COPD in HIV-Infected Patients (clinicaltrials.gov) - Oct 11, 2018
P=N/A, N=61, Active, not recruiting,
Active, not recruiting --> Completed | Trial completion date: Mar 2018 --> Mar 2017 Trial completion date: Jun 2018 --> Dec 2019
- |||||||||| doxycycline / Generic mfg.
Enrollment closed, Trial completion date, Trial primary completion date: Clinical Study to Evaluate Treatment With ORACEA® for Geographic Atrophy (TOGA) (clinicaltrials.gov) - Oct 11, 2018
P2/3, N=286, Active, not recruiting,
Trial completion date: Jun 2018 --> Dec 2019 Recruiting --> Active, not recruiting | Trial completion date: Dec 2018 --> Dec 2020 | Trial primary completion date: Jul 2018 --> Dec 2020
- |||||||||| Actemra IV (tocilizumab) / Roche, JW Pharma, Valcyte (valganciclovir) / Roche, Mitsubishi Tanabe, Kineret (anakinra) / SOBI
Enrollment open: Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants (clinicaltrials.gov) - Oct 10, 2018
P=N/A, N=500, Recruiting,
Recruiting --> Active, not recruiting | Trial completion date: Dec 2018 --> Dec 2020 | Trial primary completion date: Jul 2018 --> Dec 2020 Not yet recruiting --> Recruiting
- |||||||||| minocycline modified release (DFD-29) / Fortress
Enrollment closed, Trial completion date, Trial primary completion date: A Controlled Study to Assess the Efficacy, Safety and Tolerability of Oral DFD-29 Extended Release Capsules (clinicaltrials.gov) - Sep 21, 2018
P2, N=200, Active, not recruiting,
Trial completion date: Jun 2018 --> Mar 2019 | Trial primary completion date: May 2018 --> Mar 2019 Recruiting --> Active, not recruiting | Trial completion date: Jul 2018 --> Dec 2018 | Trial primary completion date: Jul 2018 --> Dec 2018
- |||||||||| Sivextro (tedizolid) / Merck (MSD), Nabriva Therap
Enrollment open, Trial initiation date: TEDIZOAM: Tedizolid Prolonged Treatment for Prosthetic Joint Infections (clinicaltrials.gov) - Sep 18, 2018
P=N/A, N=35, Recruiting,
Trial completion date: Dec 2019 --> Dec 2020 | Trial primary completion date: Dec 2019 --> Dec 2020 Not yet recruiting --> Recruiting | Initiation date: Jan 2018 --> Aug 2018
- |||||||||| doxycycline / Generic mfg.
Trial completion date, Trial initiation date, Trial primary completion date: Doxycycline- and Furazolidone-containing Quadruple Regimen is Superior of Tailored Therapy (clinicaltrials.gov) - Sep 5, 2018
P4, N=300, Recruiting,
Not yet recruiting --> Recruiting | Initiation date: Jan 2018 --> Aug 2018 Trial completion date: Dec 2017 --> Dec 2019 | Initiation date: May 2016 --> Feb 2016 | Trial primary completion date: Dec 2017 --> Oct 2018
- |||||||||| doxycycline / Generic mfg., azithromycin / Generic mfg.
Trial completion date, Trial primary completion date: Trial of Azithromycin vs. Doxycycline for the Treatment of Rectal Chlamydia in MSM (clinicaltrials.gov) - Aug 13, 2018
P4, N=550, Recruiting,
Trial completion date: Dec 2018 --> Nov 2022 | Trial primary completion date: Aug 2016 --> Nov 2022 Trial completion date: Oct 2018 --> Dec 2019 | Trial primary completion date: Oct 2018 --> Oct 2019
- |||||||||| Zyclara (imiquimod) / Mochida, Viatris, Bausch Health
Trial initiation date, Trial primary completion date: CTCL Directed Therapy (clinicaltrials.gov) - Aug 7, 2018
P1, N=8, Recruiting,
Trial completion date: Oct 2018 --> Dec 2019 | Trial primary completion date: Oct 2018 --> Oct 2019 Trial primary completion date: Jun 2018 --> Dec 2018 | Initiation date: Nov 2017 --> Feb 2018
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