- |||||||||| Cidine (cinitapride) / Almirall, Acofide (acotiamide) / Zeria Pharma, Astellas, Ganaton (itopride) / Abbott
Clinical, Retrospective data, Review, Journal: Prokinetics for the treatment of functional dyspepsia: an updated systematic review and network meta-analysis. (Pubmed Central) - Nov 4, 2023 Metoclopramide and cinitapride may have a better efficacy than other prokinetics in the treatment of FD, and cinitapride may have a lower risk of total adverse events. Further studies using uniform definitions or validated tools to measure the total efficacy rate are needed.
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Journal: CYP2C8*3 and *4 define CYP2C8 phenotype: An approach with the substrate cinitapride. (Pubmed Central) - Nov 16, 2022 In this study, we properly characterized RMs, NMs, and IMs; however, additional studies are required to properly characterize UMs and PMs. These findings should be relevant with respect to cinitapride, but also to numerous CYP2C8 substrates such as imatinib, loperamide, montelukast, ibuprofen, paclitaxel, pioglitazone, repaglinide, or rosiglitazone.
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Journal: Luetic gastritis: an uncommon cause of gastritis. (Pubmed Central) - Jun 30, 2021 This was associated with general symptoms including myalgia, fatigue, epigastric pain, nausea and vomiting. The patient had been taking omeprazole and cinitapride with little improvement.
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Review, Journal: Sleep related painful erection: an algorithm for evaluation and management. (Pubmed Central) - Dec 19, 2019 Based on the limited number of treatment trials and reported cases, the low level of evidence and the lack of randomized clinical trials, no treatment consensus for SRPE can be reached. We suggested a useful tool for clinicians: an algorithm for the management of SRPE to facilitate their access to the literature without exhaustive return to case reports and series upon each case faced.
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Preclinical, Journal: Stability and in vitro release kinetic studies of cinitapride (1mg) mouth dissolving tablets. (Pubmed Central) - Dec 6, 2019 Accelerated stability testing data showed excellent results of drug assay (>99%) along with physical characteristics indicating the absence of drug degradation as well excipient interaction. The estimated shelf life period of various optimized trial formulations was found in between 33 to 41 months.
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Journal: Effects of superdisintegrants in oral dissolving formulation of cinitapride tablets. (Pubmed Central) - Aug 30, 2019 The assay and content uniformity of FC2 were estimated to be 100.02±0.36 and 99.66±1.70 percent correspondingly. On the basis of the findings it was concluded that MDT could be successfully developed by incorporating appropriate concentration of superdisintegrant and their combinations.
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Journal: Development and validation of stability indicating assay method for cinitapride in bulk & tablets. (Pubmed Central) - Jul 11, 2019 However; drug estimation was not influenced in presence of degradation moieties formed during acid, base, oxidation, thermal and photolytic breakdown. Overall, the investigated technique is robust and specific that would be successfully used to quantify the cinitapride hydrogen tartarate in pharmaceutical dosage and bulk form in future.
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