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0 Diseases |  |
20 Trials |
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20 Trials |  |
1189 News |  |
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- ||||| gepotidacin (GSK2140944) / GSK
Enrollment change, Trial completion date, Trial primary completion date: EAGLE-3: Comparative Study to Evaluate Efficacy and Safety of Gepotidacin to Nitrofurantoin in Treatment of Uncomplicated Urinary Tract Infection (UTI) (clinicaltrials.gov) - Nov 13, 2020
P3, N=2020, Recruiting, Sponsor: GlaxoSmithKline
N=1200 --> 2020 | Trial completion date: Dec 2021 --> Jan 2023 | Trial primary completion date: Dec 2021 --> Jan 2023
- | nitrofurantoin / Generic mfg.
Trial completion date, Trial primary completion date, Surgery: Cranberry Tablets Versus Nitrofurantoin Prophylaxis for Urinary Tract Infection Prevention After Urogynecologic Surgery (clinicaltrials.gov) - Oct 28, 2020
P=N/A, N=142, Recruiting, Sponsor: Brigham and Women's Hospital
N=1200 --> 2020 | Trial completion date: Dec 2021 --> Jan 2023 | Trial primary completion date: Dec 2021 --> Jan 2023 Trial completion date: Jul 2020 --> Jul 2022 | Trial primary completion date: Jul 2020 --> Jul 2021
- | Enrollment closed: PREDICT: Antibiotic Prophylaxis and Renal Damage In Congenital Abnormalities of the Kidney and Urinary Tract (clinicaltrials.gov) - Aug 11, 2020
P3, N=292, Active, not recruiting, Sponsor: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Trial completion date: Jul 2020 --> Jul 2022 | Trial primary completion date: Jul 2020 --> Jul 2021 Recruiting --> Active, not recruiting
- | Invanz (ertapenem) / Merck (MSD)
Enrollment open: Prophylactic Antibiotics for Urinary Tract Infections After Robot-Assisted Radical Cystectomy (clinicaltrials.gov) - Aug 10, 2020
P4, N=100, Recruiting, Sponsor: Roswell Park Cancer Institute
Recruiting --> Active, not recruiting Not yet recruiting --> Recruiting
- | ciprofloxacin oral / Generic mfg., nitrofurantoin / Generic mfg.
Trial completion, Enrollment change: Establish the Relationship Between Shift in Prescribing Pattern and Associated Shift in Sensitivity Pattern of Causative Microbes in UTI Patients in a Closed Community (clinicaltrials.gov) - Aug 8, 2020
P4, N=62, Completed, Sponsor: Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Not yet recruiting --> Recruiting Recruiting --> Completed | N=180 --> 62
- | Invanz (ertapenem) / Merck (MSD)
New P4 trial: Prophylactic Antibiotics for Urinary Tract Infections After Robot-Assisted Radical Cystectomy (clinicaltrials.gov) - Aug 6, 2020
P4, N=100, Not yet recruiting, Sponsor: Roswell Park Cancer Institute
- |||||| gepotidacin (GSK2140944) / GSK
Enrollment open: EAGLE-3: Comparative Study to Evaluate Efficacy and Safety of Gepotidacin to Nitrofurantoin in Treatment of Uncomplicated Urinary Tract Infection (UTI) (clinicaltrials.gov) - May 4, 2020
P3, N=1200, Recruiting, Sponsor: GlaxoSmithKline
Recruiting --> Completed | N=180 --> 62 Not yet recruiting --> Recruiting
- |||| gepotidacin (GSK2140944) / GSK
Trial completion date, Trial primary completion date: EAGLE-3: Comparative Study to Evaluate Efficacy and Safety of Gepotidacin to Nitrofurantoin in Treatment of Uncomplicated Urinary Tract Infection (UTI) (clinicaltrials.gov) - Apr 12, 2020
P3, N=1200, Not yet recruiting, Sponsor: GlaxoSmithKline
Not yet recruiting --> Recruiting Trial completion date: Apr 2021 --> Dec 2021 | Trial primary completion date: Apr 2021 --> Dec 2021
- | Trial completion date, Trial primary completion date: PNLABXPART2: Endourology Disease Group Excellence (EDGE) Consortium: Antibiotics (Abx) for Percutaneous Nephrolithotomy (PCNL) Part 2 (clinicaltrials.gov) - Mar 24, 2020
P=N/A, N=330, Recruiting, Sponsor: University of California, San Diego
Trial completion date: Apr 2021 --> Dec 2021 | Trial primary completion date: Apr 2021 --> Dec 2021 Trial completion date: Jan 2020 --> Jan 2025 | Trial primary completion date: Jan 2020 --> Jan 2025
- |||||||||| gepotidacin (GSK2140944) / GSK
New P3 trial: EAGLE-3: Comparative Study to Evaluate Efficacy and Safety of Gepotidacin to Nitrofurantoin in Treatment of Uncomplicated Urinary Tract Infection (UTI) (clinicaltrials.gov) - Dec 4, 2019
P3, N=1200, Not yet recruiting, Sponsor: GlaxoSmithKline
- | Enrollment change, Trial completion date, Trial primary completion date: PREDICT: Antibiotic Prophylaxis and Renal Damage In Congenital Abnormalities of the Kidney and Urinary Tract (clinicaltrials.gov) - Nov 15, 2019
P3, N=290, Recruiting, Sponsor: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Trial completion date: Jan 2020 --> Jan 2025 | Trial primary completion date: Jan 2020 --> Jan 2025 N=436 --> 290 | Trial completion date: Dec 2021 --> Dec 2022 | Trial primary completion date: Dec 2018 --> Dec 2021
- |||||| gepotidacin (GSK2140944) / GSK
Enrollment open: EAGLE-2: A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI) (clinicaltrials.gov) - Oct 29, 2019
P3, N=1200, Recruiting, Sponsor: GlaxoSmithKline
N=436 --> 290 | Trial completion date: Dec 2021 --> Dec 2022 | Trial primary completion date: Dec 2018 --> Dec 2021 Not yet recruiting --> Recruiting
- | levofloxacin / Generic mfg., cefuroxime / Generic mfg., nitrofurantoin / Generic mfg.
Trial completion date, Trial primary completion date: The Preventive Infection Role of One Week Antibiotics Before Minimally Invasive Upper Tract Lithotomy (clinicaltrials.gov) - Oct 1, 2019
P1, N=150, Recruiting, Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Not yet recruiting --> Recruiting Trial completion date: Dec 2018 --> Dec 2019 | Trial primary completion date: Dec 2018 --> Dec 2019
- | Trial completion, Enrollment change: Examination of the Efficacy of Preventive Antibiotic Treatment During the Puerperium Among Pregnant Women With Recurrent Urinary Tract Infections (clinicaltrials.gov) - Sep 20, 2019
P=N/A, N=227, Completed, Sponsor: HaEmek Medical Center, Israel
Trial completion date: Dec 2018 --> Dec 2019 | Trial primary completion date: Dec 2018 --> Dec 2019 Recruiting --> Completed | N=100 --> 227
- | Nuzyra (omadacycline) / Paratek
Trial completion: Oral Omadacycline vs. Oral Nitrofurantoin for the Treatment of Cystitis (clinicaltrials.gov) - Jul 18, 2019
P2, N=225, Completed, Sponsor: Paratek Pharmaceuticals Inc
Recruiting --> Completed | N=100 --> 227 Active, not recruiting --> Completed
- | gepotidacin (GSK2140944) / GSK
New P3 trial: EAGLE-2: A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI) (clinicaltrials.gov) - Jul 15, 2019
P3, N=1200, Not yet recruiting, Sponsor: GlaxoSmithKline
- | nitrofurantoin / Generic mfg.
Trial completion, Trial primary completion date, Surgery: NAUTICA: Nitrofurantoin Administration for the Prevention of Short-Term Catheter Associated Urinary Tract Infection After Pelvic Surgery (clinicaltrials.gov) - Jul 5, 2019
P4, N=164, Completed, Sponsor: Atrium Health
Active, not recruiting --> Completed Recruiting --> Completed | Trial primary completion date: Jan 2019 --> May 2019
- | Trial completion date, Trial primary completion date: PNLABXPART2: Endourology Disease Group Excellence (EDGE) Consortium: Antibiotics (Abx) for Percutaneous Nephrolithotomy (PCNL) Part 2 (clinicaltrials.gov) - Jun 26, 2019
P=N/A, N=330, Recruiting, Sponsor: University of California, San Diego
Recruiting --> Completed | Trial primary completion date: Jan 2019 --> May 2019 Trial completion date: Jan 2019 --> Jan 2020 | Trial primary completion date: Jan 2019 --> Jan 2020
- | Trial completion, Trial completion date, Surgery: A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Kidney Stone Surgery (Percutaneous Nephrolithotomy [PCNL]) (clinicaltrials.gov) - Jun 25, 2019
P4, N=83, Completed, Sponsor: University of California, San Diego
Trial completion date: Jan 2019 --> Jan 2020 | Trial primary completion date: Jan 2019 --> Jan 2020 Active, not recruiting --> Completed | Trial completion date: Dec 2017 --> Jun 2019
- | gentamicin sulfate / Generic mfg., nitrofurantoin / Generic mfg.
Enrollment change, Trial completion date, Trial withdrawal, Trial primary completion date: INSTANT: INtravesical Antimicrobial Agents v STANDard Oral Antibiotics for the Treatment of Acute UTI in Women With rUTI (clinicaltrials.gov) - Jun 6, 2019
P4, N=0, Withdrawn, Sponsor: Mayo Clinic
Active, not recruiting --> Completed | Trial completion date: Dec 2017 --> Jun 2019 N=40 --> 0 | Trial completion date: Jul 2019 --> Jul 2018 | Recruiting --> Withdrawn | Trial primary completion date: Jul 2019 --> Jul 2018
- ||| Nuzyra (omadacycline) / Paratek
Enrollment closed: Oral Omadacycline vs. Oral Nitrofurantoin for the Treatment of Cystitis (clinicaltrials.gov) - May 10, 2019
P2, N=225, Active, not recruiting, Sponsor: Paratek Pharmaceuticals Inc
N=40 --> 0 | Trial completion date: Jul 2019 --> Jul 2018 | Recruiting --> Withdrawn | Trial primary completion date: Jul 2019 --> Jul 2018 Recruiting --> Active, not recruiting
- || Nuzyra (omadacycline) / Paratek
Trial completion date, Trial primary completion date: Oral Omadacycline vs. Oral Nitrofurantoin for the Treatment of Cystitis (clinicaltrials.gov) - Apr 2, 2019
P2, N=200, Recruiting, Sponsor: Paratek Pharmaceuticals Inc
Recruiting --> Active, not recruiting Trial completion date: Mar 2019 --> Jul 2019 | Trial primary completion date: Mar 2019 --> Jun 2019
- | ciprofloxacin oral / Generic mfg., nitrofurantoin / Generic mfg.
New P4 trial: Establish the Relationship Between Shift in Prescribing Pattern and Associated Shift in Sensitivity Pattern of Causative Microbes in UTI Patients in a Closed Community (clinicaltrials.gov) - Oct 23, 2018
P4, N=180, Recruiting, Sponsor: Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
- | nitrofurantoin / Generic mfg.
Enrollment open, Surgery: Cranberry Tablets Versus Nitrofurantoin Prophylaxis for Urinary Tract Infection Prevention After Urogynecologic Surgery (clinicaltrials.gov) - Sep 20, 2018
P=N/A, N=142, Recruiting, Sponsor: Brigham and Women's Hospital
Trial completion date: Mar 2019 --> Jul 2019 | Trial primary completion date: Mar 2019 --> Jun 2019 Not yet recruiting --> Recruiting
- | nitrofurantoin / Generic mfg.
Trial completion, Surgery: Nitrofurantoin Prophylaxis During Catheter-managed Acute Urinary Retention After Pelvic Reconstructive Surgery (clinicaltrials.gov) - Jun 19, 2018
P4, N=154, Completed, Sponsor: Charelle Carter-Brooks
Not yet recruiting --> Recruiting Recruiting --> Completed
- | nitrofurantoin / Generic mfg.
New trial, Surgery: Cranberry Tablets Versus Nitrofurantoin Prophylaxis for Urinary Tract Infection Prevention After Urogynecologic Surgery (clinicaltrials.gov) - May 18, 2018
P=N/A, N=142, Not yet recruiting, Sponsor: Brigham and Women's Hospital
- | cephalexin / Generic mfg., nitrofurantoin / Generic mfg.
Enrollment change, Trial completion date, Trial termination, Trial primary completion date: Treatment of Asymptomatic Bacteriuria in Pregnancy (clinicaltrials.gov) - Apr 18, 2018
P=N/A, N=13, Terminated, Sponsor: Saint Joseph Mercy Health System
Recruiting --> Completed N=101 --> 13 | Trial completion date: Mar 2019 --> Jan 2018 | Recruiting --> Terminated | Trial primary completion date: Jun 2018 --> Jan 2018; Inability to enroll patients at anticipated rate.
- ||||| Nuzyra (omadacycline) / Paratek
New P2 trial: Oral Omadacycline vs. Oral Nitrofurantoin for the Treatment of Cystitis (clinicaltrials.gov) - Feb 13, 2018
P2, N=200, Recruiting, Sponsor: Paratek Pharmaceuticals Inc
- | Enrollment closed, Surgery: A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Kidney Stone Surgery (Percutaneous Nephrolithotomy [PCNL]) (clinicaltrials.gov) - Oct 27, 2017
P4, N=83, Active, not recruiting, Sponsor: University of California, San Diego
N=101 --> 13 | Trial completion date: Mar 2019 --> Jan 2018 | Recruiting --> Terminated | Trial primary completion date: Jun 2018 --> Jan 2018; Inability to enroll patients at anticipated rate. Recruiting --> Active, not recruiting
- | gentamicin sulfate / Generic mfg., nitrofurantoin / Generic mfg.
New P4 trial: INSTANT: INtravesical Antimicrobial Agents v STANDard Oral Antibiotics for the Treatment of Acute UTI in Women With rUTI (clinicaltrials.gov) - Oct 3, 2017
P4, N=40, Recruiting, Sponsor: Mayo Clinic
- | nitrofurantoin / Generic mfg.
Trial primary completion date, Surgery: Nitrofurantoin Prophylaxis During Catheter-managed Acute Urinary Retention After Pelvic Reconstructive Surgery (clinicaltrials.gov) - Sep 28, 2017
P4, N=154, Recruiting, Sponsor: Charelle Carter-Brooks
Recruiting --> Active, not recruiting Trial primary completion date: Aug 2017 --> Mar 2018
- | nitrofurantoin / Generic mfg.
New P4 trial, Surgery: NAUTICA: Nitrofurantoin Administration for the Prevention of Short-Term Catheter Associated Urinary Tract Infection After Pelvic Surgery (clinicaltrials.gov) - Sep 19, 2017
P4, N=180, Recruiting, Sponsor: Carolinas Healthcare System
- | Trial primary completion date: PREDICT: Antibiotic Prophylaxis and Renal Damage In Congenital Abnormalities of the Kidney and Urinary Tract (clinicaltrials.gov) - Jun 29, 2017
P3, N=436, Recruiting, Sponsor: Azienda Ospedaliera Universitaria di Bologna Policlinico S. Orsola Malpighi
Trial primary completion date: Aug 2017 --> Mar 2018 Trial primary completion date: Jun 2017 --> Dec 2018
- | nitrofurantoin / Generic mfg., fosfomycin tromethamine / Generic mfg.
Enrollment closed, Trial primary completion date: AIDA-WP2: Study Comparing Nitrofurantoin to Fosfomycin for Acute Urinary Tract Infection in Women (clinicaltrials.gov) - May 2, 2017
P4, N=600, Active, not recruiting, Sponsor: University Hospital, Geneva
Trial primary completion date: Jun 2017 --> Dec 2018 Recruiting --> Active, not recruiting | Trial primary completion date: Oct 2016 --> May 2017
- | cephalexin / Generic mfg., nitrofurantoin / Generic mfg.
Trial completion: AnTIC: Antibiotic Prophylaxis for Clean Intermittent Catheterisation (clinicaltrials.gov) - Mar 29, 2017
P4, N=404, Completed, Sponsor: Newcastle-upon-Tyne Hospitals NHS Trust
Recruiting --> Active, not recruiting | Trial primary completion date: Oct 2016 --> May 2017 Recruiting --> Completed
- | linezolid oral / Generic mfg.
Clinical data, Enrollment open: PRESTO:Osteo: Patients Response to Early Switch To Oral:Osteomyelitis Study (clinicaltrials.gov) - Mar 24, 2017
P, N=456, Recruiting, Sponsor: Julio Ramirez
Recruiting --> Completed Not yet recruiting --> Recruiting
- Enrollment open, Trial primary completion date: Examination of the Efficacy of Preventive Antibiotic Treatment During the Puerperium Among Pregnant Women With Recurrent Urinary Tract Infections (clinicaltrials.gov) - Nov 1, 2016
P=N/A, N=100, Recruiting, Sponsor: HaEmek Medical Center, Israel
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting | Trial primary completion date: Jan 2013 --> May 2017
- nitrofurantoin / Generic mfg.
Enrollment open, Trial initiation date, Surgery: Nitrofurantoin Prophylaxis During Catheter-managed Acute Urinary Retention After Pelvic Reconstructive Surgery (clinicaltrials.gov) - Oct 25, 2016
P4, N=154, Recruiting, Sponsor: University of Pittsburgh
Not yet recruiting --> Recruiting | Trial primary completion date: Jan 2013 --> May 2017 Not yet recruiting --> Recruiting | Initiation date: Apr 2016 --> Aug 2016
- cephalexin / Generic mfg., nitrofurantoin / Generic mfg.
New trial: Treatment of Asymptomatic Bacteriuria in Pregnancy (clinicaltrials.gov) - Sep 22, 2016
P=N/A, N=101, Recruiting, Sponsor: Saint Joseph Mercy Health System
- New trial: PNLABXPART2: Endourology Disease Group Excellence (EDGE) Consortium: Antibiotics (Abx) for Percutaneous Nephrolithotomy (PCNL) Part 2 (clinicaltrials.gov) - Jul 12, 2016
P=N/A, N=330, Recruiting, Sponsor: University of California, San Diego
- levofloxacin / Generic mfg., cefuroxime / Generic mfg., nitrofurantoin / Generic mfg.
New trial: The Preventive Infection Role of One Week Antibiotics Before Minimally Invasive Upper Tract Lithotomy (clinicaltrials.gov) - Jun 4, 2016
P0, N=150, Not yet recruiting, Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
- | nitrofurantoin / Generic mfg.
New P4 trial, Surgery: Nitrofurantoin Prophylaxis During Catheter-managed Acute Urinary Retention After Pelvic Reconstructive Surgery (clinicaltrials.gov) - Apr 4, 2016
P4, N=154, Not yet recruiting, Sponsor: University of Pittsburgh
- |||| Enrollment open: Preoperative Antibiotic PNL Study (clinicaltrials.gov) - Mar 22, 2016
P4, N=80, Enrolling by invitation, Sponsor: University of British Columbia
Not yet recruiting --> Recruiting | Initiation date: Apr 2016 --> Aug 2016 Active, not recruiting --> Enrolling by invitation
- |||| Enrollment open, Surgery: A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Kidney Stone Surgery (Percutaneous Nephrolithotomy [PCNL]) (clinicaltrials.gov) - Feb 11, 2016
P4, N=80, Recruiting, Sponsor: University of California, San Diego
Active, not recruiting --> Enrolling by invitation Not yet recruiting --> Recruiting
- nitrofurantoin / Generic mfg.
Enrollment change, Trial termination, Surgery: APPIC: Nitrofurantoin and Urinary Tract Infections (UTIs) (clinicaltrials.gov) - Jan 26, 2016
P=N/A, N=10, Terminated, Sponsor: University of Pittsburgh
Not yet recruiting --> Recruiting N=108 --> 10 | Recruiting --> Terminated; Inadequate patient recruitment
- cephalexin / Generic mfg., nitrofurantoin / Generic mfg.
Trial primary completion date: AnTIC: Antibiotic Prophylaxis for Clean Intermittent Catheterisation (clinicaltrials.gov) - Oct 23, 2015
P4, N=372, Recruiting, Sponsor: Newcastle-upon-Tyne Hospitals NHS Trust
N=108 --> 10 | Recruiting --> Terminated; Inadequate patient recruitment Trial primary completion date: Aug 2016 --> Dec 2016
- ||||| New P4 trial: Preoperative Antibiotic PNL Study (clinicaltrials.gov) - Apr 3, 2015
P4, N=80, Active, not recruiting, Sponsor: University of British Columbia
- ||||| New P4 trial, Surgery: A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Kidney Stone Surgery (Percutaneous Nephrolithotomy [PCNL]) (clinicaltrials.gov) - Mar 10, 2015
P4, N=80, Not yet recruiting, Sponsor: University of California, San Diego
- nitrofurantoin / Generic mfg., fosfomycin tromethamine / Generic mfg.
Enrollment open: AIDA-WP2: Study Comparing Nitrofurantoin to Fosfomycin for Acute Urinary Tract Infection in Women (clinicaltrials.gov) - Aug 5, 2014
P4, N=600, Recruiting, Sponsor: University Hospital, Geneva
Trial primary completion date: Aug 2016 --> Dec 2016 Not yet recruiting --> Recruiting
- | cephalexin / Generic mfg., nitrofurantoin / Generic mfg.
New P4 trial: AnTIC: Antibiotic Prophylaxis for Clean Intermittent Catheterisation (clinicaltrials.gov) - May 19, 2014
P4, N=372, Recruiting, Sponsor: Newcastle-upon-Tyne Hospitals NHS Trust