nitrofurantoin / Generic mfg. 
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  • ||||||||||  nitrofurantoin / Generic mfg.
    Journal:  Detection of nitrofurans residues in honey using surface-enhanced Raman spectroscopy. (Pubmed Central) -  Jul 24, 2022   
    Considering the overuse of nitrofurans in honeybee breeding, SERS combined with spectral preprocessing was used to detect nitrofurantoin in honey...The original spectra were corrected by multiple linear regression based on the fitting baseline. This study aims to develop a rapid onsite detection method for toxic hazardous substance residues in food.
  • ||||||||||  Journal:  Retail Chicken Carcasses as a Reservoir of Multidrug-Resistant Salmonella. (Pubmed Central) -  Jul 20, 2022   
    Additionally, 43.3% of the isolates were MDR and associated with frozen chicken (OR = 16.88, 95% CI: 2.55-111.47, p = 0.002). The findings indicate that while the prevalence of Salmonella in retail chicken in Qatar is moderate, a large proportion of them are MDR.
  • ||||||||||  Lantus (insulin glargine) / Sanofi
    Journal:  Development of Diagnostic Capabilities for Complications of Bacterial Infection in Diabetic Patients. (Pubmed Central) -  Jul 15, 2022   
    It was followed by Staphylococcus hominis (11%), Pseudomonas aeruginosa (9%), Enterococcus faecalis (9%), Enterococcus fiseum (7%), Escherichia coli (7%), Staphylococcus aureus (7%), Staphylococcus lantus (5%) and Klebsiella pneumoniae (5%)...Most of the organisms were susceptible to tigecycline, gentamycin, and nitrofurantoin, rating (88%), (84%) and (78%), respectively...Tigecycline had a wide sensitivity spectrum and was effective against most of the bacteria. Thus, it can be used as an empirical antibiotic.
  • ||||||||||  nitrofurantoin / Generic mfg.
    Journal:  Associated epidemiologic factors with recurring infection of the lower urinary tract in pregnant women (Pubmed Central) -  Jul 12, 2022   
    Of a total of 90 electronic records of pregnant women, a recurrence of lower urinary tract infections was found in 41 patients (45.6%). The prevalence of recurring lower urinary tract infections during pregnancy in our population is alarming in whom no association was found with the presence of the epidemiologic factors studied in the present investigation; however, a tendency of recurrence urinary tract infections was identified in women that are not working, superior level of education, 2 pregnancies or less, patients under 20 years of age and in those who were treated with nitrofurantoin for a period of time less than 7 days.
  • ||||||||||  Journal:  Corynebacterium pseudotuberculosis Infections in Alpacas (Vicugna pacos). (Pubmed Central) -  Jul 11, 2022   
    In this context, it should be emphasized that evaluation of these investigations and the epidemiological data suggest an incubation period of one to two months. Antibiotic susceptibility testing of 13 C. pseudotuberculosis isolates based on the determination of minimal inhibitory concentrations using the broth microdilution method revealed uniform susceptibility to aminopenicillins, cephalosporines, macrolides, enrofloxacin, florfenicol, tetracycline, sulfonamid/trimethoprime, tiamulin, gentamicin, neomycin, spectinomycin, and vancomycin, but resistance to colistin, nitrofurantoin, and oxacillin.
  • ||||||||||  nitrofurantoin / Generic mfg.
    Journal:  Acute lung toxicity by nitrofurantoin. (Pubmed Central) -  Jul 2, 2022   
    This phenomenon (AMR) has critical repercussions on the final consumer health; therefore, it represents a crucial One-Health issue. No abstract available
  • ||||||||||  Journal:  Occurrence and Genomic Characterization of Clone ST1193 Clonotype 14-64 in Uncomplicated Urinary Tract Infections Caused by Escherichia coli in Spain. (Pubmed Central) -  Jul 2, 2022   
    Multidrug resistance to at least one antibiotic of ≥ 3 antimicrobial categories were exhibited by 30% of the isolates, with the highest rates of resistance against ampicillin/amoxicillin (48%), trimethoprim (35%), norfloxacin (28%), amoxicillin-clavulanic acid (26%), and trimethoprim-sulfamethoxazole (24%)...According to our results, fosfomycin and nitrofurantoin should be considered as empirical treatment of choice for uUTI by E. coli (resistance rates 4% and 2%, respectively)...IMPORTANCE Analyzing the clonal structure and antimicrobial resistance of E. coli isolates implicated in uncomplicated urinary tract infections, one of the most frequent visits managed in primary health care, is of interest for clinicians to detect changes in the dynamics of emerging uropathogenic clones associated with the spread of fluoroquinolone resistance. It can also provide consensus concerning optimal control and antibiotic prescribing.
  • ||||||||||  Journal:  Genomic Analysis of Two MDR Isolates of Salmonella enterica Serovar Infantis from a Spanish Hospital Bearing the bla Gene with or without fosA3 in pESI-like Plasmids. (Pubmed Central) -  Jun 25, 2022   
    Antimicrobial susceptibility testing demonstrated that they were resistant to eight classes of antimicrobial agents: penicillins, cephalosporins, phenicols, aminoglycosides, tetracyclines, inhibitors of folate synthesis, (fluoro)quinolones and nitrofurans, and one of them was also resistant to fosfomycin...The two isolates had a D87Y amino acid substitution in the GyrA protein, and truncated variants of the nitroreductase genes nfsA and nsfB, accounting for chromosomally encoded resistances to nalidixic acid and nitrofurantoin, respectively...They were also genetically similar to bla-positive ± fosA3 isolates obtained from humans and along the poultry production chain in the USA, South America, as well as from humans in several European countries, usually associated with a travel history to America. However, this is the first time that the S. Infantis bla ± fosA3 MDR clone has been reported in Spain.
  • ||||||||||  Journal:  Quantifying community-wide antimicrobials usage via wastewater-based epidemiology. (Pubmed Central) -  Jun 24, 2022   
    Acetyl-sulfonamides, trimethoprim, hydroxy-metronidazole, clarithromycin, ciprofloxacin, ofloxacin, tetracycline, and oxytetracycline generally performed well in the estimation of drug intake, relative to prescription records. The low prevalence of quinolone and trimethoprim metabolites, and the low stability of nitrofurantoin, limited the ability to evaluate these metabolites and their respective CFs.
  • ||||||||||  Journal:  Twelve-year trend of Escherichia coli antibiotic resistance in the Islamabad population. (Pubmed Central) -  Jun 24, 2022   
    There was a decrease in susceptibility rates of E. coli to Amoxicillin-Clavulanic Acid 47%, Trimethoprim-Sulfamethoxazole (TMP-SMX) 27%, Fluoroquinolones 24% & Cephalosporins 38%...However, significantly high degree of sensitivity rates to Fosfomycin (92%), Aminoglycosides (90%) & Nitrofurantoin (80%) were recorded...Cephalosporins, Amoxicillin/Cluvalanic acid, TMP-SMX, and Fluoroquinolones show a declining sensitivity pattern. UTIs can be prevented well by lifestyle changes, taking vitamins, trace elements, and carbohydrates.
  • ||||||||||  ciprofloxacin oral / Generic mfg., fosfomycin tromethamine / Generic mfg.
    Journal:  Efficacy of Single Dose of Fosfomycin Versus a Five-Day Course of Ciprofloxacin in Patients With Uncomplicated Urinary Tract Infection. (Pubmed Central) -  Jun 18, 2022   
    In group A, there were 15 (65.21%) patients with efficacy achieved, and among eight (34.78%) patients, efficacy was not achieved while in group B, there were 15 (65.21%) patients in which efficacy was achieved, and among eight (34.78%) patients, efficacy was not achieved. There was no significant association between efficacy and study groups as the p-value was not significant (p=0.87).  The conclusion of the study was that in the treatment of simple urinary infections, a single dose of fosfomycin had equal efficacy and tolerability as a five-day course of ciprofloxacin.
  • ||||||||||  nitrofurantoin / Generic mfg.
    Nitrofurantoin-induced ARDS in immunosuppressed patient: a case report (Poster eBoard 5) -  Jun 17, 2022 - Abstract #Euroanaesthesia2022Euroanaesthesia_1253;    
    Treatment with steroids was initiated and her immunosuppressive therapy was adapted. Nitrofurantoin pulmonary drug side-effects are rare but can result in life-threating conditions and prolonged hospitalisations. Pulmonary pathologies associated with nitrofurantoin toxicity include cryptogenic organizing pneumonia, diffuse alveolar haemorrhage and acute, sub-acute or chronic interstitial lung disease.The gold-treatment remains withdrawal of the drug.
  • ||||||||||  Journal:  Antibiotic resistance pattern and pathological features of avian pathogenic Escherichia coli O78:K80 in chickens. (Pubmed Central) -  Jun 15, 2022   
    Histopathological examination depicted hepatocellular degeneration, myocardial necrosis, interstitial nephritis, intestinal hemorrhages and lymphopenia in the spleen. This study is the first evidence to assess the antibiotic resistance profile linked with virulence genes and clinicopathological potential of APEC O78:K80 in chickens in Pakistan, which could be a useful and rapid approach to prevent and control the disease by developing the control strategies.
  • ||||||||||  ampicillin / Generic mfg., tigecycline / Generic mfg., nitrofurantoin / Generic mfg.
    Journal:  Antibiotic Susceptibility Patterns of ESβL Producers Isolated from the Mobile Phones. (Pubmed Central) -  Jun 8, 2022   
    Gram positive has highest incidence of sensitivity towards tigecycline (100%) and lowest in cefoxitin (20%)...Interestingly, some soil microbes were also isolated and unfortunately found to have some antibiotic resistance like Raoultella ornithinolytica and Sphingomonas paucimobilis. The results revealed that mobiles were contaminated with multidrug-resistant (MDR) pathogens, and this study also showed that few of the saprophytic soil strains have antibiotic resistance, which can be an alarming situation that needs to be addressed.
  • ||||||||||  ceftriaxone / Generic mfg., tetracycline / Generic mfg., nitrofurantoin / Generic mfg.
    Whole-Genome Surveillance of Serratia Marcescens in a Hospital System Reveals Potential High Risk Clades in a Diverse Population (Exhibit and Poster Hall) -  Jun 4, 2022 - Abstract #ASMMicrobe2022ASM_Microbe_3633;    
    Whole-genome scrutiny of S. marcescens associated with hospital BSIs ruled-out a putative outbreak and revealed a highly variable population. Closely related isolates did not exhibit phenotype resistance to relevant antibiotics, suggesting that clonal expansion from antibiotic intervention remains limited in this population.
  • ||||||||||  ciprofloxacin oral / Generic mfg., nitrofurantoin / Generic mfg., fosfomycin tromethamine / Generic mfg.
    Combinatory Effects of Isothiocyanate and Antibiotics Against K. Pneumoniae, E.coli and P. Mirabilis (Exhibit and Poster Hall) -  Jun 4, 2022 - Abstract #ASMMicrobe2022ASM_Microbe_2772;    
    Inconclusion we hereby show that ITC combined with either fosfomycin or imepinem antibiotics has both additive and efficacy increase in P.mirabilis, E.coli and K.pnuemoniae strains at considerable low concentrations of 0.0025-0.02 μg/mL % ITC. The combination of ITC and antibiotics promises a better alternate to fight multi-drug resistance strains as more data-based evidence comes to our knowledge.
  • ||||||||||  Invanz (ertapenem) / Merck (MSD)
    Journal:  Direct Urine Resistance Detection Using VITEK 2. (Pubmed Central) -  May 30, 2022   
    Cefepime, imipenem, and tobramycin had no major errors (ME)...The antibiotic with the most minor errors (mE) was ceftazidime...The direct AST from the urine samples proposed here was shorter by one day, without significant loss of sensibility regarding the standard diagnosis. Therefore, we hypothesize that this method is more realistic and better suited to human antibiotic concentrations.