lomefloxacin / Generic mfg. 
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  • ||||||||||  roxithromycin / Generic mfg., lomefloxacin / Generic mfg., ibuprofen / Generic mfg.
    Journal:  Non-targeted Screening and Ecological Risk Assessment of Emerging Contaminants in Beijiang Drinking Water Source of the Pearl River Delta (Pubmed Central) -  Dec 4, 2024   
    for ATZ and Lomefloxacin ?LOM?, while for 4-NP, it was determined to be high only at sampling site 2 ?S2?...The concentration level of ATZ exhibited significant seasonal variation due to its agricultural origin, so it is recommended to strengthen control during spring. Overall, this research provides critical insights into a comprehensive understanding of the presence and impact of ECs in this specific region.
  • ||||||||||  lomefloxacin / Generic mfg., tetracycline / Generic mfg.
    Journal:  Toxicological mechanisms and molecular impacts of tire particles and antibiotics on zebrafish. (Pubmed Central) -  Nov 14, 2024   
    Therefore, the joint toxicity of styrene-butadiene rubber TMPs (SBR-TMPs) and 32 antibiotics (macrolides, fluoroquinolones, ?-lactams, sulfonamides, tetracyclines, nitroimidazoles, highly toxic antibiotics, high-content antibiotics, and common antibiotics) in zebrafish was investigated using a full factorial design, molecular docking, and molecular dynamics simulation...Results indicated that low-order effects of antibiotics (e.g., enoxacin-lomefloxacin and ofloxacin-enoxacin-lomefloxacin) had relatively notable toxicity...Zebrafish hepatotoxicity was also affected by the ability of SBR-TMPs to adsorb antibiotics, the relation between antibiotics, the affinity of antibiotics docking to zebrafish cytochrome P450 enzymes, electronegativity, atomic mass, and the hydrophobicity of the antibiotic molecules. This study aimed to eliminate the joint toxicity of TMPs and antibiotics and provide more environmentally friendly instructions for using different chemicals.
  • ||||||||||  Preclinical, Journal:  Aldose reductase with quinolone antibiotics interaction: In vitro and in silico approach of its relationship with diabetic complications. (Pubmed Central) -  Nov 13, 2024   
    This study aimed to eliminate the joint toxicity of TMPs and antibiotics and provide more environmentally friendly instructions for using different chemicals. In this study, we evaluated the inhibitory potential of five quinolone antibiotics-gatifloxacin, lomefloxacin, nalidixic acid, norfloxacin, and sparfloxacin-as ARIs relevant to various physiological and pathological conditions...Our findings reveal that these quinolones moderately inhibit AR at micromolar concentrations, with inhibition constants (KIs) ranging from 1.03
  • ||||||||||  lomefloxacin / Generic mfg.
    Journal:  Quantum dot-based fluorescence-linked immunosorbent assay for the rapid detection of lomefloxacin in animal-derived foods. (Pubmed Central) -  Apr 29, 2024   
    The recoveries of dc-FLISA and ic-FLISA in animal-derived foods (milk, fish, chicken, and honey), ranged from 95.8% to 105.2% and from 96.3% to 103.4%, respectively, with the coefficients of variation less than 8%. These results suggest that the dc-FLISA and ic-FLISA methods, which are based on QD labelling, are highly sensitive and cost-effective, and can be effectively used to detect LMF in animal-derived foods.
  • ||||||||||  lomefloxacin / Generic mfg.
    Journal:  Physicochemical properties as a function of lomefloxacin biological activity. (Pubmed Central) -  Apr 24, 2024   
    These results suggest that the dc-FLISA and ic-FLISA methods, which are based on QD labelling, are highly sensitive and cost-effective, and can be effectively used to detect LMF in animal-derived foods. The parameters used for calculation were depending on the quantum chemical was employed in deriving from computational study of properties and can used to predict the activities of certain analogs of Lomefloxacins as antibacterial compounds.
  • ||||||||||  lomefloxacin / Generic mfg.
    Journal:  Encapsulate Co3O4 within ultrathin graphene sheets to enhance peroxymonosulfate activation by tuning surface electronic structures. (Pubmed Central) -  Mar 23, 2024   
    This study synthesized a heterojunction material of graphene sheets encapsulating Co3O4 (GCO-500) through the pyrolysis of cobalt MOF and applied it to activate PMS for the removal of lomefloxacin...In the meanwhile, organic pollutant was enriched in graphene layers with high adsorption energy (-13.08?eV), which greatly enhanced the degradation efficiency of pharmaceuticals. This study provides an effective catalyst for PMS activation and sheds light on the fundamental electronic-level understanding of cobalt-based and carbon heterojunction catalysts in PMS activation.
  • ||||||||||  Journal:  Relation of Streptococcus Pyogenes tonsillitis isolate to antimicrobial agents and its infection treatment. (Pubmed Central) -  Mar 7, 2024   
    The Streptococcus pyogenes BS1 demonstrated intermediate susceptibility to the cephalosporin cephalexin, fluoroquinolone lomefloxacin and glycopeptide vancomycin...The antimicrobial applications of "Stomatidin", "Chlorophyllipt" and phages of "Pyofag" in the patient were less effective compared to the result of antibiotic benzathine phenoxymethylpenicillin treatment. Complete recovery of the patient was achieved with use of this antibiotic and Calendula flower extract as an local anti-inflammatory agent.
  • ||||||||||  lomefloxacin / Generic mfg.
    Retrospective data, Review, Journal:  Prevalence of Brucella melitensis and Brucella abortus Fluoroquinolones Resistant Isolates: A Systematic Review and Meta-Analysis. (Pubmed Central) -  Oct 20, 2023   
    The resistance rates to ofloxacin, sparfloxacin, fleroxacin, pefloxacin, and lomefloxacin were 2%, 1.6%, and 4.6%, respectively...Owing to first-line medication resistance, recurrence, and toxicity, it is essential to standardize the Brucella antimicrobial susceptibility test method for a more precise screening of resistance status. Fluoroquinolones are less resistant to fluoroquinolone-based treatments in modern clinical practice as alternatives to standard therapy for patients with brucellosis relapse after treatment with another regimen and in patients who have developed toxicity from older agents.
  • ||||||||||  lomefloxacin / Generic mfg.
    Journal:  Phosphorus-modified copper ferrite (P-CuFeO) nanoparticles for photocatalytic ozonation of lomefloxacin. (Pubmed Central) -  Sep 11, 2023   
    The findings of this study demonstrate that the introduction of phosphorus modification into the copper ferrite photocatalyst led to an augmentation of both the specific surface area and the total pore volume. Furthermore, the incorporation of phosphorus served to promote the efficient separation of electron-hole pairs by effectively trapping electrons in the conduction band, hence enhancing the degradation efficiency.
  • ||||||||||  Journal:  Comprehensive profiling of serotypes, antimicrobial resistance and virulence of Salmonella isolates from food animals in China, 2015-2021. (Pubmed Central) -  Apr 21, 2023   
    Antibiotic susceptibility testing showing that the majority of the Salmonella isolates were resistant to neomycin (99.7%), tetracycline (98.1%), ampicillin (97.4%), sulfadiazine/trimethoprim (97.1%), nalidixic acid (89.1%), doxycycline (83.1%), ceftria xone (70.3%), spectinomycin (67.7%), florfenicol (60.0%), cefotaxime (52.0%) and lomefloxacin (59.8%)...However, the rate of resistance to fosfomycin were observed from higher to lower by S. Derby, S. Enteritidis, and S. Typhimurium...12 out of 17 virulence genes selected in this study were commonly presented in the chromosomes of tested isolate, with a detection rate of over 80%, including misL, spiA, stn, pagC, iroN, fim, msgA, sopB, prgH, sitC, ttrC, spaN. This study provided a systematical updating on surveillance on prevalence of Salmonella from food animals in China, shedding the light on continued vigilance for Salmonella in food animals.
  • ||||||||||  lomefloxacin / Generic mfg.
    Journal, Heterogeneity:  Degradation of lomefloxacin by MoS/MIL-53(Fe, Cu) catalyst in heterogeneous electro-Fenton process. (Pubmed Central) -  Apr 5, 2023   
    This study provided a systematical updating on surveillance on prevalence of Salmonella from food animals in China, shedding the light on continued vigilance for Salmonella in food animals. Furthermore, the hetero-EF system could achieve the total removal of moxifloxacin and tetracycline within 6
  • ||||||||||  ciprofloxacin oral / Generic mfg., norfloxacin / Generic mfg., lomefloxacin / Generic mfg.
    Journal:  Simultaneous adsorptive removal of three fluoroquinolones using humic acid modified hydrogel beads. (Pubmed Central) -  Feb 27, 2023   
    This study elaborates the simultaneous removal of three different fluoroquinolones (FQs), i.e., Norfloxacin (NOR), Lomefloxacin (LOM), and Enrofloxacin (ENR) from water using hydrogel beads of humic acid coated biochar (HA-BC) and chitosan. Adsorbent was desorbed and regenerated for consecutive removal, and it showed good adsorption in the 4 cycle, i.e., 47
  • ||||||||||  lomefloxacin / Generic mfg.
    Journal:  Insight into catalytic activation of bisulfite for lomefloxacin degradation by simple composite of calcinated red mud. (Pubmed Central) -  Nov 22, 2022   
    In addition, the potential LOM degradation pathway was analyzed via UPLC-MS technology and density functional theory (DFT) calculation, and the toxicity of the treated LOM solution was tested by the culture of mung bean sprouts. This study not only provided a feasible strategy for the valuable use of RM to activate NaHSO but also offered a cost-effective catalyst for the efficient removal of pollutants in wastewater.
  • ||||||||||  almitrine - Public Assistance / Paris Hospitals
    Preclinical, Journal:  Drug Repurposing Based on Protozoan Proteome: In Vitro Evaluation of In Silico Screened Compounds against Toxoplasma gondii. (Pubmed Central) -  Aug 27, 2022   
    Almitrine demonstrated a Selectivity Index (provided by the ratio between the Half Cytotoxic Concentration against human foreskin fibroblasts and the Half Effective Concentration against T. gondii tachyzoites) that was higher than 47, whilst being considered a lead compound against T. gondii. Almitrine showed interactions with the Na/K ATPase transporter for Homo sapiens and Mus musculus, indicating a possible mechanism of action of this compound.
  • ||||||||||  ciprofloxacin oral / Generic mfg., norfloxacin / Generic mfg., lomefloxacin / Generic mfg.
    Journal:  Simultaneous Determination of Nine Quinolones in Pure Milk Using PFSPE-HPLC-MS/MS with PS-PAN Nanofibers as a Sorbent. (Pubmed Central) -  Jul 11, 2022   
    The nine quinolones in the complex matrix were directly extracted using 4.0 mg of PS-PAN composite nanofibers as a sorbent and completely eluted in 100 μL elution solvent. Therefore, the developed PFSPE-HPLC-MS/MS is a sensitive and cost-effective technique that can effectively detect and control nine quinolones in dairy products.
  • ||||||||||  norfloxacin / Generic mfg., lomefloxacin / Generic mfg., sulphadiazine / Generic mfg.
    Journal:  Ca(OH)-mediated activation of peroxymonosulfate for the degradation of bisphenol S. (Pubmed Central) -  May 3, 2022   
    The degradation of BPS was lower in domestic wastewater compared to other naturals waters and ultrapure; nevertheless, up to 75.86%, 77.94% and 81.48% of BPS was degraded in domestic wastewater, Yaohu Lake water and Poyang Lake water, respectively. Finally, phenolic chemicals and antibiotics, including bisphenol A, norfloxacin, lomefloxacin hydrochloride, and sulfadiazine could also be efficiently removed via the Ca(OH)/PMS system.