dilmapimod (SB-681323) / GSK 
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 39 Diseases   0 Trials   0 Trials   6 News 
  • ||||||||||  dilmapimod (SB-681323) / GSK, Mektovi (binimetinib) / Ono Pharma, Pierre Fabre, Pfizer, talmapimod (SCIO-469) / J&J
    Journal, Immunomodulating:  Bioinformatic approach for repurposing immunomodulatory drugs for lepromatous leprosy. (Pubmed Central) -  Dec 27, 2023   
    Consistently, glucosamine, binimetinib, talmapimod, dilmapimod, andrographolide, and VX-702 might have a possible beneficial effect coupled with LL treatment. Based on our drug repurposing analysis, immunomodulatory drugs might have a promising potential to be explored further as therapeutic options or to alleviate symptoms in LL patients.
  • ||||||||||  dilmapimod (SB-681323) / GSK
    Trial completion:  SB-681323 IV for Subjects at Risk of Acute Lung Injury or ARDS (clinicaltrials.gov) -  Apr 10, 2013   
    P2,  N=90, Completed, 
    Based on our drug repurposing analysis, immunomodulatory drugs might have a promising potential to be explored further as therapeutic options or to alleviate symptoms in LL patients. Recruiting --> Completed
  • ||||||||||  dilmapimod (SB-681323) / GSK
    Enrollment change:  SB-681323-Methotrexate Interaction Study (clinicaltrials.gov) -  Jan 12, 2012   
    P1,  N=18, Completed, 
    Recruiting --> Completed N=15 --> 18