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37 Trials |
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37 Trials |  |
1094 News |  |
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- Trial primary completion date: SMAC AF: Atrial Substrate Modification With Aggressive Blood Pressure Lowering to Prevent AF (clinicaltrials.gov) - Oct 7, 2015
P4, N=184, Recruiting, Sponsor: Nova Scotia Health Authority
Trial primary completion date: Jun 2015 --> Nov 2015
- |||| Entresto (sacubitril/valsartan) / Novartis, ROVI Pharmaceuticals Laboratories
Trial completion: Study of the Safety and Efficacy of LCZ696 on Arterial Stiffness in Elderly Patients With Hypertension (clinicaltrials.gov) - Oct 7, 2015
P2, N=454, Completed, Sponsor: Novartis Pharmaceuticals
Trial primary completion date: Jun 2015 --> Nov 2015 Active, not recruiting --> Completed
- chlorthalidone / Generic mfg., hydrochlorothiazide / Generic mfg.
Trial initiation date: DCP: Diuretic Comparison Project (clinicaltrials.gov) - Jun 11, 2015
P=N/A, N=13500, Not yet recruiting, Sponsor: Department of Veterans Affairs
Active, not recruiting --> Completed Initiation date: Jun 2015 --> Sep 2015
- || Kanarb (fimasartan) - Boryung Group, R / Pharm
New P3 trial: FIRME-1: Efficacy and Safety of Fimasartan Alone or Combined With HCTZ in Mexican Patients With Essential Hypertension (clinicaltrials.gov) - Jun 9, 2015
P3, N=272, Completed, Sponsor: Stendhal Americas, S.A.
- hydrochlorothiazide / Generic mfg., lisinopril / Generic mfg.
Enrollment change: 1HAT: Hypertensive Ambulatory Trial to Compare the Efficacy of HCTZ and Lisinopril (clinicaltrials.gov) - May 20, 2015
P=N/A, N=2, Completed, Sponsor: Scripps Translational Science Institute
Initiation date: Jun 2015 --> Sep 2015 N=10 --> 2
- Tekturna (aliskiren) / PDL
Enrollment change, Trial withdrawal: Aliskiren vs Hydrochlorothiazide in Hypertensive Type II Diabetic Patients on Resistance Arteries (clinicaltrials.gov) - May 19, 2015
P2, N=0, Withdrawn, Sponsor: Sir Mortimer B. Davis - Jewish General Hospital
N=10 --> 2 N=40 --> 0 | Suspended --> Withdrawn
- acetazolamide / Generic mfg., hydrochlorothiazide / Generic mfg., furosemide / Generic mfg.
New P4 trial: Role of Acetazolamide and Hydrochlorothiazide Followed by Furosemide in Treating Nephrotic Edema (clinicaltrials.gov) - Apr 30, 2015
P4, N=20, Completed, Sponsor: Shiraz University of Medical Sciences
- chlorthalidone / Generic mfg., hydrochlorothiazide / Generic mfg.
Enrollment change, Trial withdrawal, Trial primary completion date: Chlorthalidone Compared to Hydrochlorothiazide on Endothelial Function (clinicaltrials.gov) - Apr 15, 2015
P4, N=0, Withdrawn, Sponsor: Creighton University
N=40 --> 0 | Suspended --> Withdrawn N=30 --> 0 | Recruiting --> Withdrawn | Trial primary completion date: Jul 2015 --> Feb 2015
- Trial primary completion date: Treatment of Supine Hypertension in Autonomic Failure (clinicaltrials.gov) - Apr 14, 2015
P1/2, N=160, Recruiting, Sponsor: Vanderbilt University
N=30 --> 0 | Recruiting --> Withdrawn | Trial primary completion date: Jul 2015 --> Feb 2015 Trial primary completion date: Sep 2015 --> Sep 2016
- hydrochlorothiazide / Generic mfg., lisinopril / Generic mfg.
New trial: Series of N-of-1 Crossover Trials of Antihypertensive Therapy in Adolescents With Essential Hypertension (clinicaltrials.gov) - Apr 9, 2015
P=N/A, N=50, Enrolling by invitation, Sponsor: The University of Texas Health Science Center, Houston
- ||||| valsartan / Generic mfg.
Enrollment closed: Safety and Tolerability of Valsartan in Children 6 to 17 Years of Age (clinicaltrials.gov) - Apr 8, 2015
P3, N=150, Active, not recruiting, Sponsor: Novartis Pharmaceuticals
Trial primary completion date: Sep 2015 --> Sep 2016 Recruiting --> Active, not recruiting
- |||||| hydrochlorothiazide / Generic mfg.
Enrollment open: A Phase III Long-term Study of TAK-536TCH in Participants With Essential Hypertension (clinicaltrials.gov) - Apr 1, 2015
P3, N=330, Recruiting, Sponsor: Takeda
Recruiting --> Active, not recruiting Not yet recruiting --> Recruiting
- | hydrochlorothiazide / Generic mfg.
Trial completion, Enrollment change, Combination therapy: A Pilot Study of Plasma Renin Activity Guided vs Generic Combination Therapy for Hypertension (clinicaltrials.gov) - Mar 27, 2015
P=N/A, N=17, Completed, Sponsor: University of North Carolina, Chapel Hill
Not yet recruiting --> Recruiting Active, not recruiting --> Completed | N=24 --> 17
- Trial primary completion date: SMAC AF: Atrial Substrate Modification With Aggressive Blood Pressure Lowering to Prevent AF (clinicaltrials.gov) - Jan 28, 2015
P4, N=184, Recruiting, Sponsor: Capital District Health Authority, Canada
Active, not recruiting --> Completed | N=24 --> 17 Trial primary completion date: Dec 2014 --> Jun 2015
- ||| hydrochlorothiazide / Generic mfg., lisinopril / Generic mfg.
Combination therapy: The Effects on Blood Pressure Control, Pulse Wave Velocity, as Well as Safety and Tolerability of Felodipine Sustained Release in Chinese Patients. (clinicaltrials.gov) - Jan 13, 2015
P=N/A, N=529, Completed, Sponsor: AstraZeneca
- hydrochlorothiazide / Generic mfg., furosemide / Generic mfg.
Trial primary completion date: Clinical Trial to Compare Effectiveness of Diuretics in Hemodialysis Patients With Residual Renal Function (clinicaltrials.gov) - Dec 5, 2014
P4, N=36, Recruiting, Sponsor: Corporacion Parc Tauli
Trial primary completion date: Dec 2014 --> Jun 2015 Trial primary completion date: Nov 2014 --> Mar 2015
- hydrochlorothiazide / Generic mfg.
Enrollment change, Trial termination, Trial primary completion date: Mechanisms of Ramipril Reduction in the Onset of Type 2 Diabetes (clinicaltrials.gov) - Dec 5, 2014
P=N/A, N=24, Terminated, Sponsor: University of Maryland
Trial primary completion date: Nov 2014 --> Mar 2015 N=48 --> 24 | Recruiting --> Terminated | Trial primary completion date: Dec 2015 --> Aug 2014; Lack of funding
- Trial primary completion date: UFLC: Effect of Renin-angiotensin-system Blockade on Urinary Free Light Chains in Patients With Type 2 Diabetes Mellitus (clinicaltrials.gov) - Nov 20, 2014
P4, N=30, Recruiting, Sponsor: Tulane University Health Sciences Center
N=48 --> 24 | Recruiting --> Terminated | Trial primary completion date: Dec 2015 --> Aug 2014; Lack of funding Trial primary completion date: Dec 2014 --> Dec 2015
- hydrochlorothiazide / Generic mfg.
Enrollment open, Trial primary completion date: CLOROTIC: Safety and Efficacy of the Combination of Loop With Thiazide-type Diuretics in Patients With Decompensated Heart Failure (clinicaltrials.gov) - Oct 30, 2014
P4, N=400, Recruiting, Sponsor: Spanish Society of Internal Medicine
Trial primary completion date: Dec 2014 --> Dec 2015 Not yet recruiting --> Recruiting | Trial primary completion date: Jun 2015 --> Oct 2015
- |||||||||| hydrochlorothiazide / Generic mfg.
New P3 trial: A Phase III Long-term Study of TAK-536TCH in Participants With Essential Hypertension (clinicaltrials.gov) - Oct 30, 2014
P3, N=330, Not yet recruiting, Sponsor: Takeda
- Kanarb (fimasartan) - Boryung Group, R / Pharm
Enrollment open, Combination therapy: A Clinical Trial to Evaluate Efficacy, Tolerability, and Pharmacokinetic-Pharmacodynamic Relationship of Fimasartan/Hydrochlorothiazide (clinicaltrials.gov) - Oct 17, 2014
P2, N=0, Recruiting, Sponsor: Boryung Pharmaceutical Co., Ltd
Not yet recruiting --> Recruiting | Trial primary completion date: Jun 2015 --> Oct 2015 Not yet recruiting --> Recruiting
- Kanarb (fimasartan) - Boryung Group, R / Pharm
New P2 trial, Combination therapy: A Clinical Trial to Evaluate Efficacy, Tolerability, and Pharmacokinetic-Pharmacodynamic Relationship of Fimasartan/Hydrochlorothiazide (clinicaltrials.gov) - Aug 21, 2014
P2, N=0, Not yet recruiting, Sponsor: Boryung Pharmaceutical Co., Ltd
- | hydrochlorothiazide / Generic mfg., captopril / Generic mfg.
New P4 trial: Treatment of Hypertension in Tibetan Adult Population (clinicaltrials.gov) - Aug 15, 2014
P4, N=800, Not yet recruiting, Sponsor: West China Hospital
- chlorthalidone / Generic mfg., hydrochlorothiazide / Generic mfg.
Trial primary completion date: Chlorthalidone Compared to Hydrochlorothiazide on Endothelial Function (clinicaltrials.gov) - Aug 12, 2014
P4, N=30, Recruiting, Sponsor: Creighton University
Not yet recruiting --> Recruiting Trial primary completion date: Jul 2014 --> Jul 2015
- | hydrochlorothiazide / Generic mfg., enalapril / Generic mfg.
New P4 trial: THYME: Treatment of HYpertension: Morning Versus Evening (clinicaltrials.gov) - Aug 12, 2014
P4, N=120, Not yet recruiting, Sponsor: Erasmus Medical Center
- ||| Trial completion: Bioequivalence Study of Telmisartan Between T80/A5/H12.5 mg FDC Tablet and T80/A5 mg Tab and H12.5 mg Tab Concomitant Use (clinicaltrials.gov) - Aug 8, 2014
P1, N=72, Completed, Sponsor: Boehringer Ingelheim
Trial primary completion date: Jul 2014 --> Jul 2015 Not yet recruiting --> Completed
- ||| Entresto (sacubitril/valsartan) / Novartis, ROVI Pharmaceuticals Laboratories
Enrollment closed: Study of the Safety and Efficacy of LCZ696 on Arterial Stiffness in Elderly Patients With Hypertension (clinicaltrials.gov) - Aug 5, 2014
P2, N=439, Active, not recruiting, Sponsor: Novartis Pharmaceuticals
Not yet recruiting --> Completed Recruiting --> Active, not recruiting
- hydrochlorothiazide / Generic mfg., furosemide / Generic mfg.
Trial primary completion date: Clinical Trial to Compare Effectiveness of Diuretics in Hemodialysis Patients With Residual Renal Function (clinicaltrials.gov) - Aug 1, 2014
P4, N=36, Recruiting, Sponsor: Corporacion Parc Tauli
Recruiting --> Active, not recruiting Trial primary completion date: Jul 2014 --> Nov 2014
- | candesartan cilexetil / Generic mfg., hydrochlorothiazide / Generic mfg.
Trial completion: A Relative Bioavailability Study of a Fixed Dose Combination (FDC) Tablets of GSK587323 (clinicaltrials.gov) - Jul 1, 2014
P1, N=16, Completed, Sponsor: GlaxoSmithKline
Trial primary completion date: Jul 2014 --> Nov 2014 Active, not recruiting --> Completed
- hydrochlorothiazide / Generic mfg.
Trial primary completion date: CLOROTIC: Safety and Efficacy of the Combination of Loop With Thiazide-type Diuretics in Patients With Decompensated Heart Failure (clinicaltrials.gov) - Jun 26, 2014
P4, N=400, Not yet recruiting, Sponsor: Spanish Society of Internal Medicine
Active, not recruiting --> Completed Trial primary completion date: Dec 2013 --> Jun 2015
- hydrochlorothiazide / Generic mfg.
Trial initiation date, Trial primary completion date: CLOROTIC: Safety and Efficacy of the Combination of Loop With Thiazide-type Diuretics in Patients With Decompensated Heart Failure (clinicaltrials.gov) - Jun 26, 2014
P4, N=400, Not yet recruiting, Sponsor: Spanish Society of Internal Medicine
Trial primary completion date: Dec 2013 --> Jun 2015 Initiation date: Jan 2013 --> Sep 2014 | Trial primary completion date: Dec 2013 --> Jun 2015
- hydrochlorothiazide / Generic mfg.
Enrollment change, Combination therapy: Indapamide Versus Hydrochlorothiazide in Elderly Hypertensive Patients With Renal Insufficiency (clinicaltrials.gov) - Jun 26, 2014
P4, N=240, Completed, Sponsor: West China Hospital
Initiation date: Jan 2013 --> Sep 2014 | Trial primary completion date: Dec 2013 --> Jun 2015 N=200 --> 240
- hydrochlorothiazide / Generic mfg.
Trial completion, Enrollment change, Combination therapy: Indapamide Versus Hydrochlorothiazide in Elderly Hypertensive Patients With Renal Insufficiency (clinicaltrials.gov) - Jun 26, 2014
P4, N=240, Completed, Sponsor: West China Hospital
N=200 --> 240 Not yet recruiting --> Completed | N=200 --> 240
- candesartan cilexetil / Generic mfg., hydrochlorothiazide / Generic mfg.
Enrollment closed: A Relative Bioavailability Study of a Fixed Dose Combination (FDC) Tablets of GSK587323 (clinicaltrials.gov) - May 28, 2014
P1, N=18, Active, not recruiting, Sponsor: GlaxoSmithKline
Not yet recruiting --> Completed | N=200 --> 240 Recruiting --> Active, not recruiting
- hydrochlorothiazide / Generic mfg.
Trial primary completion date: Mechanisms of Ramipril Reduction in the Onset of Type 2 Diabetes (clinicaltrials.gov) - May 26, 2014
P=N/A, N=48, Recruiting, Sponsor: University of Maryland
Recruiting --> Active, not recruiting Trial primary completion date: Dec 2014 --> Dec 2015
- hydrochlorothiazide / Generic mfg.
Trial completion date: Mechanisms of Ramipril Reduction in the Onset of Type 2 Diabetes (clinicaltrials.gov) - May 26, 2014
P=N/A, N=48, Recruiting, Sponsor: University of Maryland
Trial primary completion date: Dec 2014 --> Dec 2015 Trial completion date: Dec 2014 --> Dec 2015
- Trial primary completion date: Treatment of Supine Hypertension in Autonomic Failure (clinicaltrials.gov) - May 1, 2014
P1/2, N=160, Recruiting, Sponsor: Vanderbilt University
Trial completion date: Dec 2014 --> Dec 2015 Trial primary completion date: Sep 2014 --> Sep 2015
- Trial completion date: Treatment of Supine Hypertension in Autonomic Failure (clinicaltrials.gov) - May 1, 2014
P1/2, N=160, Recruiting, Sponsor: Vanderbilt University
Trial primary completion date: Sep 2014 --> Sep 2015 Trial completion date: Sep 2014 --> Sep 2016
- candesartan cilexetil / Generic mfg., hydrochlorothiazide / Generic mfg.
Enrollment open: A Relative Bioavailability Study of a Fixed Dose Combination (FDC) Tablets of GSK587323 (clinicaltrials.gov) - Apr 30, 2014
P1, N=18, Recruiting, Sponsor: GlaxoSmithKline
Trial completion date: Sep 2014 --> Sep 2016 Not yet recruiting --> Recruiting
- ||| New P1 trial: Bioequivalence Study of Telmisartan Between T80/A5/H12.5 mg FDC Tablet and T80/A5 mg Tab and H12.5 mg Tab Concomitant Use (clinicaltrials.gov) - Apr 21, 2014
P1, N=72, Not yet recruiting, Sponsor: Boehringer Ingelheim
- hydrochlorothiazide / Generic mfg.
Enrollment closed, Combination therapy: A Pilot Study of Plasma Renin Activity Guided vs Generic Combination Therapy for Hypertension (clinicaltrials.gov) - Apr 6, 2014
P=N/A, N=24, Active, not recruiting, Sponsor: University of North Carolina, Chapel Hill
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- | chlorthalidone / Generic mfg., hydrochlorothiazide / Generic mfg.
New P4 trial: Chlorthalidone and HCTZ Impacts on Platelet Activation (clinicaltrials.gov) - Mar 30, 2014
P4, N=30, Recruiting, Sponsor: Creighton University
- hydrochlorothiazide / Generic mfg., lisinopril / Generic mfg.
Trial completion: 1HAT: Hypertensive Ambulatory Trial to Compare the Efficacy of HCTZ and Lisinopril (clinicaltrials.gov) - Mar 30, 2014
P=N/A, N=10, Completed, Sponsor: Scripps Translational Science Institute
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- | candesartan cilexetil / Generic mfg., hydrochlorothiazide / Generic mfg.
New P1 trial: A Relative Bioavailability Study of a Fixed Dose Combination (FDC) Tablets of GSK587323 (clinicaltrials.gov) - Mar 20, 2014
P1, N=18, Not yet recruiting, Sponsor: GlaxoSmithKline
- |||||||||| hydrochlorothiazide / Generic mfg.
New P2/3 trial, Monotherapy: Study to Evaluate the Efficacy and Safety of Combined Administration of TAK-536CCB and Hydrochlorothiazide in Patients With Grade I or II Essential Hypertension. (clinicaltrials.gov) - Feb 24, 2014
P2/3, N=353, Completed, Sponsor: Takeda
- |||| CoAprovel (irbesartan hydrochlorothiazide) / Sanofi
Trial completion: Irbesartan in the Treatment of Hypertensive Patients With Metabolic Syndrome (clinicaltrials.gov) - Feb 22, 2014
P4, N=400, Completed, Sponsor: Bristol-Myers Squibb
Active, not recruiting --> Completed No longer recruiting --> Completed
- ||||||| CoAprovel (irbesartan hydrochlorothiazide) / Sanofi
Trial completion, Combination therapy: Irbesartan/Hydrochlorothiazide (HCTZ) Combination Therapy for Patients With Moderate Hypertension (clinicaltrials.gov) - Feb 22, 2014
P3, N=496, Completed, Sponsor: Bristol-Myers Squibb
No longer recruiting --> Completed No longer recruiting --> Completed
- ||||||| CoAprovel (irbesartan hydrochlorothiazide) / Sanofi
Trial completion, Combination therapy: Irbesartan/Hydrochlorothiazide (HCTZ) Combination Therapy as First Line Treatment for Severe Hypertension (clinicaltrials.gov) - Feb 22, 2014
P3, N=645, Completed, Sponsor: Bristol-Myers Squibb
No longer recruiting --> Completed No longer recruiting --> Completed
- | candesartan cilexetil / Generic mfg., hydrochlorothiazide / Generic mfg.
Trial completion: GERA: Genetic Epidemiology of Responses to Antihypertensives (clinicaltrials.gov) - Feb 19, 2014
P=N/A, N=1200, Completed, Sponsor: Mayo Clinic
No longer recruiting --> Completed No longer recruiting --> Completed
- hydrochlorothiazide / Generic mfg., losartan potassium / Generic mfg., perindopril arginine / Generic mfg.
Trial initiation date: ACES-P: ACE Inhibitors Combined With Exercise for Seniors - Pilot Study (clinicaltrials.gov) - Feb 9, 2014
P2, N=72, Recruiting, Sponsor: University of Florida
No longer recruiting --> Completed Initiation date: Oct 2013 --> Jan 2014