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138 Diseases |  |
94 Trials |
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94 Trials |  |
2090 News |  |
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- | Vesanoid (tretinoin) / Roche
New P2 trial: A Pilot Study of 5-AZA and ATRA for Prostate Cancer With PSA-only Recurrence After Local Treatment (clinicaltrials.gov) - Jun 27, 2018
P2, N=20, Recruiting, Sponsor: Icahn School of Medicine at Mount Sinai
- || leuprolide acetate for depot suspension / Generic mfg.
Enrollment change, Trial completion date, Trial primary completion date: CRONOS II: Evaluation of Diet and Exercise in Prostate Cancer Patients (clinicaltrials.gov) - Jun 21, 2018
P=N/A, N=1300, Recruiting, Sponsor: AbbVie
N=860 --> 1300 | Trial completion date: Jul 2021 --> Aug 2022 | Trial primary completion date: Jul 2021 --> Aug 2022
- || Trial completion: Exisulind and Intermittent Androgen Suppression (ADT) in Biochemical Relapsed Prostate Cancer (clinicaltrials.gov) - Jun 3, 2018
P2, N=32, Completed, Sponsor: University of Washington
N=860 --> 1300 | Trial completion date: Jul 2021 --> Aug 2022 | Trial primary completion date: Jul 2021 --> Aug 2022 Active, not recruiting --> Completed
- | leuprolide acetate for depot suspension / Generic mfg.
New P3 trial: GRAET: GnRH Agonist at Embryo Transfer: IVF Outcomes (clinicaltrials.gov) - Jun 2, 2018
P3, N=442, Not yet recruiting, Sponsor: Maimonides Medical Center
- || Kepivance (palifermin) / SOBI, Amgen, Firmagon (degarelix) / Astellas, Ferring
Trial completion date, Trial primary completion date: Palifermin With Leuprolide Acetate for the Promotion of Immune Recovery Following Total Body Irradiation Based T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation (clinicaltrials.gov) - Jun 1, 2018
P2, N=93, Recruiting, Sponsor: Memorial Sloan Kettering Cancer Center
Active, not recruiting --> Completed Trial completion date: Dec 2018 --> Dec 2019 | Trial primary completion date: Dec 2018 --> Dec 2019
- | leuprolide acetate for depot suspension / Generic mfg., docetaxel / Generic mfg.
Enrollment closed, Enrollment change, Trial completion date, Trial primary completion date: A Registry for Patients Treated on the Clinical Trial TAX 3503 (clinicaltrials.gov) - Jun 1, 2018
P3, N=52, Active, not recruiting, Sponsor: Memorial Sloan Kettering Cancer Center
Trial completion date: Dec 2018 --> Dec 2019 | Trial primary completion date: Dec 2018 --> Dec 2019 Enrolling by invitation --> Active, not recruiting | N=19 --> 52 | Trial completion date: Mar 2018 --> Mar 2019 | Trial primary completion date: Mar 2018 --> Mar 2019
- | valacyclovir / Generic mfg.
New P2 trial, Combination therapy, Surgery, Gene therapy: Phase II High Risk Prostate Cancer Trial Using Gene & Androgen Deprivation Therapies, Radiotherapy, & Surgery (clinicaltrials.gov) - May 31, 2018
P2, N=60, Not yet recruiting, Sponsor: The Methodist Hospital System
- | Xtandi (enzalutamide capsule) / Pfizer, Astellas
Enrollment closed, Enrollment change: Trial of Radiotherapy With Leuprolide and Enzalutamide in High Risk Prostate Cancer (clinicaltrials.gov) - May 4, 2018
P2, N=11, Active, not recruiting, Sponsor: Hao Nguyen
Enrolling by invitation --> Active, not recruiting | N=19 --> 52 | Trial completion date: Mar 2018 --> Mar 2019 | Trial primary completion date: Mar 2018 --> Mar 2019 Recruiting --> Active, not recruiting | N=53 --> 11
- || Erleada (apalutamide) / J&J
Trial completion date, Trial primary completion date: Apalutamide Plus Intermittent Hormone Therapy Versus Intermittent Hormone Therapy Alone in Prostate Cancer (clinicaltrials.gov) - Apr 30, 2018
P2, N=66, Not yet recruiting, Sponsor: Robert J Amato
Recruiting --> Active, not recruiting | N=53 --> 11 Trial completion date: Dec 2022 --> Dec 2023 | Trial primary completion date: Dec 2021 --> Jul 2022
- | letrozole / Generic mfg.
New P2 trial: NeoChAI: Neo-adjuvant Chemotherapy With Letrozole in Patients With Estrogen Receptor Positive/HER-2 Negative Breast Cancer (clinicaltrials.gov) - Apr 12, 2018
P2, N=114, Recruiting, Sponsor: National Cancer Center, Korea
- | goserelin acetate / Generic mfg., leuprolide acetate for depot suspension / Generic mfg., bicalutamide / Generic mfg.
Trial completion date, Trial primary completion date: CCRO025: Stereotactic Boost and Long-Term Androgen Deprivation for Adenocarcinoma of the Prostate (clinicaltrials.gov) - Apr 11, 2018
P=N/A, N=29, Recruiting, Sponsor: University of California, Davis
Trial completion date: Dec 2022 --> Dec 2023 | Trial primary completion date: Dec 2021 --> Jul 2022 Trial completion date: Mar 2018 --> Oct 2018 | Trial primary completion date: Mar 2018 --> Oct 2018
- | leuprolide acetate for depot suspension / Generic mfg.
Phase classification: A Treatment Study for Premenstrual Syndrome (PMS) (clinicaltrials.gov) - Apr 4, 2018
P, N=100, Recruiting, Sponsor: National Institute of Mental Health (NIMH)
Trial completion date: Mar 2018 --> Oct 2018 | Trial primary completion date: Mar 2018 --> Oct 2018 Phase classification: P=N/A --> P
- | leuprolide acetate for depot suspension / Generic mfg.
Phase classification: The Effects of Reproductive Hormones on Mood and Behavior (clinicaltrials.gov) - Mar 30, 2018
P, N=150, Recruiting, Sponsor: National Institute of Mental Health (NIMH)
Phase classification: P=N/A --> P Phase classification: P=N/A --> P
- | Xtandi (enzalutamide capsule) / Pfizer, Astellas, Erleada (apalutamide) / J&J
Phase classification, Trial completion date, Trial primary completion date: Micro RNAs to Predict Response to Androgen Deprivation Therapy (clinicaltrials.gov) - Mar 27, 2018
P, N=60, Recruiting, Sponsor: Medical College of Wisconsin
Phase classification: P=N/A --> P Phase classification: P=N/A --> P | Trial completion date: Dec 2020 --> Feb 2022 | Trial primary completion date: Feb 2018 --> Feb 2021
- | Erleada (apalutamide) / J&J
Enrollment open: A Salvage Trial of AR Inhibition With ADT and Apalutamide With Radiation Therapy Followed by Docetaxel in Men With PSA Recurrent Prostate Cancer After Radical Prostatectomy (STARTAR) (clinicaltrials.gov) - Mar 22, 2018
P2, N=42, Recruiting, Sponsor: Tian Zhang, MD
Phase classification: P=N/A --> P | Trial completion date: Dec 2020 --> Feb 2022 | Trial primary completion date: Feb 2018 --> Feb 2021 Not yet recruiting --> Recruiting
- | Erleada (apalutamide) / J&J
Enrollment open, Metastases: SOLAR: Systemic and Tumor-Directed Therapy for Oligometastatic Prostate Cancer (clinicaltrials.gov) - Mar 13, 2018
P2, N=28, Recruiting, Sponsor: VA Office of Research and Development
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- || leuprolide acetate for depot suspension / Generic mfg.
Trial completion date, Trial primary completion date: CRONOS II: Evaluation of Diet and Exercise in Prostate Cancer Patients (clinicaltrials.gov) - Mar 8, 2018
P=N/A, N=860, Recruiting, Sponsor: AbbVie
Not yet recruiting --> Recruiting Trial completion date: Nov 2020 --> Jul 2021 | Trial primary completion date: Nov 2020 --> Jul 2021
- || leuprolide acetate for depot suspension / Generic mfg.
Enrollment closed: Special Drug Use Surveillance of Leuprorelin for Injection Kit 22.5 mg in "Premenopausal Breast Cancer" (clinicaltrials.gov) - Mar 6, 2018
P=N/A, N=312, Active, not recruiting, Sponsor: Takeda
Trial completion date: Nov 2020 --> Jul 2021 | Trial primary completion date: Nov 2020 --> Jul 2021 Recruiting --> Active, not recruiting
- | docetaxel / Generic mfg.
Trial completion date, Metastases: Docetaxel, Radiation Therapy, and Hormone Therapy in Treating Patients With Locally Advanced Prostate Cancer (clinicaltrials.gov) - Mar 3, 2018
P1, N=20, Active, not recruiting, Sponsor: Medical University of South Carolina
Recruiting --> Active, not recruiting Trial completion date: Dec 2017 --> Dec 2018
- || leuprolide acetate for depot suspension / Generic mfg.
Trial completion date, Trial primary completion date: A Study to Assess the Safety and Efficacy of Enantone (Leuprorelin) in Central Precocious Puberty (CPP) Among Chinese Participants (clinicaltrials.gov) - Feb 28, 2018
P=N/A, N=300, Recruiting, Sponsor: Takeda
Trial completion date: Dec 2017 --> Dec 2018 Trial primary completion date: Feb 2018 --> Sep 2018 | Trial completion date: Feb 2018 --> Sep 2018
- | Menopur (menotropin) / Ferring, Follistim AQ Cartridge (follitropin beta) / Organon, Bravelle (urofollitropin) / Ferring
Enrollment change: Maximal Stimulation and Delayed Fertilization for Diminished Ovarian Reserve: a Randomized Pilot Study (clinicaltrials.gov) - Feb 23, 2018
P4, N=23, Completed, Sponsor: Carolinas Healthcare System
Trial primary completion date: Feb 2018 --> Sep 2018 | Trial completion date: Feb 2018 --> Sep 2018 N=100 --> 23
- | Xtandi (enzalutamide capsule) / Pfizer, Astellas
Enrollment closed, Metastases: LHRH Analogue Therapy With Enzalutamide or Bicalutamide in Treating Patients With Hormone Sensitive Prostate Cancer (clinicaltrials.gov) - Feb 13, 2018
P2, N=92, Active, not recruiting, Sponsor: Barbara Ann Karmanos Cancer Institute
N=100 --> 23 Recruiting --> Active, not recruiting
- | Menopur (menotropin) / Ferring, Orgalutran (ganirelix acetate) / Organon, Follistim AQ Cartridge (follitropin beta) / Organon
Trial completion, Trial primary completion date: Efficacy of Recombinant FSH/GnRH Antagonist Protocol With and Without LH Adjunct for Egg Bank Donation (clinicaltrials.gov) - Feb 13, 2018
P4, N=39, Completed, Sponsor: Michigan Reproductive Medicine
Recruiting --> Active, not recruiting Recruiting --> Completed | Trial primary completion date: Apr 2018 --> Feb 2017
- || Erleada (apalutamide) / J&J
Trial completion date, Trial primary completion date: c15-164: AASUR in High Risk Prostate Cancer (clinicaltrials.gov) - Feb 13, 2018
P2, N=58, Recruiting, Sponsor: Memorial Sloan Kettering Cancer Center
Recruiting --> Completed | Trial primary completion date: Apr 2018 --> Feb 2017 Trial primary completion date: May 2018 --> May 2019 | Trial completion date: May 2018 --> May 2019
- | leuprolide acetate for depot suspension / Generic mfg.
Enrollment change, Trial completion date, Trial initiation date, Trial withdrawal, Trial primary completion date: Treatment of Uterine Fibroids With Magnetic Resonance Guided High Intensity Focused Ultrasound (clinicaltrials.gov) - Feb 6, 2018
P3, N=0, Withdrawn, Sponsor: Thunder Bay Regional Research Institute
Trial primary completion date: May 2018 --> May 2019 | Trial completion date: May 2018 --> May 2019 N=30 --> 0 | Initiation date: Mar 2017 --> Jan 2018 | Not yet recruiting --> Withdrawn | Trial primary completion date: Mar 2019 --> Jan 2018 | Trial completion date: Mar 2020 --> Jan 2018
- | New P4 trial: Aromatase Plus GnRH Analogue Versus GnRH Analog Alone in Adenomyosis (clinicaltrials.gov) - Feb 5, 2018
P4, N=150, Recruiting, Sponsor: Centre for Endocrinology and Reproductive Medicine, Italy
- | cabazitaxel / Generic mfg.
Trial primary completion date: ACDC-RP: Anti-Androgens and Cabazitaxel in Defining Complete Response in Prostatectomy (ACDC Trial) (clinicaltrials.gov) - Feb 1, 2018
P2, N=76, Recruiting, Sponsor: University Health Network, Toronto
N=30 --> 0 | Initiation date: Mar 2017 --> Jan 2018 | Not yet recruiting --> Withdrawn | Trial primary completion date: Mar 2019 --> Jan 2018 | Trial completion date: Mar 2020 --> Jan 2018 Trial primary completion date: Oct 2018 --> Aug 2019
- | Erleada (apalutamide) / J&J
Trial initiation date, Trial primary completion date: A Salvage Trial of AR Inhibition With ADT and Apalutamide With Radiation Therapy Followed by Docetaxel in Men With PSA Recurrent Prostate Cancer After Radical Prostatectomy (STARTAR) (clinicaltrials.gov) - Jan 24, 2018
P2, N=42, Not yet recruiting, Sponsor: Tian Zhang, MD
Trial primary completion date: Oct 2018 --> Aug 2019 Initiation date: Dec 2017 --> Mar 2018 | Trial primary completion date: Dec 2023 --> Mar 2024
- | leuprolide acetate for depot suspension / Generic mfg.
Phase classification, Trial initiation date, Trial primary completion date: Effect of Short Term Ovarian Suppression on Androgen Overproduction in Overweight Girls With Androgen Excess (clinicaltrials.gov) - Jan 23, 2018
P1, N=20, Not yet recruiting, Sponsor: University of Virginia
Initiation date: Dec 2017 --> Mar 2018 | Trial primary completion date: Dec 2023 --> Mar 2024 Phase classification: P=N/A --> P1 | Initiation date: Jun 2017 --> Jun 2018 | Trial primary completion date: Jun 2018 --> Jun 2019
- | Erleada (apalutamide) / J&J
Trial primary completion date: Apalutamide and Leuprolide in Intermediate and High-risk Prostate Cancer (clinicaltrials.gov) - Jan 23, 2018
P2, N=57, Recruiting, Sponsor: Case Comprehensive Cancer Center
Phase classification: P=N/A --> P1 | Initiation date: Jun 2017 --> Jun 2018 | Trial primary completion date: Jun 2018 --> Jun 2019 Trial primary completion date: Oct 2017 --> Dec 2018
- | Ibrance (palbociclib) / Pfizer
Enrollment change, Trial primary completion date, Combination therapy, Metastases: A Study of Palbociclib With Exemestane Plus GnRH Versus Capecitabine in Premenopausal Women With HR+ MBC (clinicaltrials.gov) - Jan 17, 2018
P2, N=182, Recruiting, Sponsor: Samsung Medical Center
Trial primary completion date: Oct 2017 --> Dec 2018 N=122 --> 182 | Trial primary completion date: Sep 2019 --> Jun 2021
- | leuprolide acetate for depot suspension / Generic mfg.
Trial completion, Phase classification, Enrollment change, Trial primary completion date: Impact of Hot Flashes on Sleep and Mood Disturbance (clinicaltrials.gov) - Dec 26, 2017
P4, N=29, Completed, Sponsor: Massachusetts General Hospital
N=122 --> 182 | Trial primary completion date: Sep 2019 --> Jun 2021 Active, not recruiting --> Completed | Phase classification: PN/A --> P4 | N=50 --> 29 | Trial primary completion date: Jun 2014 --> Dec 2011
- | leuprolide acetate for depot suspension / Generic mfg.
Trial primary completion date: Pilot Study of Leuprolide to Improve Immune Function After Allogeneic Bone Marrow Transplantation (clinicaltrials.gov) - Dec 11, 2017
P2, N=70, Active, not recruiting, Sponsor: National Cancer Institute (NCI)
Active, not recruiting --> Completed | Phase classification: PN/A --> P4 | N=50 --> 29 | Trial primary completion date: Jun 2014 --> Dec 2011 Trial primary completion date: Dec 2018 --> Nov 2020
- | leuprolide acetate for depot suspension / Generic mfg.
Trial primary completion date: Pilot Study of Leuprolide to Improve Immune Function After Allogeneic Bone Marrow Transplantation (clinicaltrials.gov) - Dec 8, 2017
P2, N=70, Active, not recruiting, Sponsor: National Cancer Institute (NCI)
Trial primary completion date: Dec 2018 --> Nov 2020 Trial primary completion date: Dec 2017 --> Dec 2018
- | leuprolide acetate for depot suspension / Generic mfg.
Trial completion, Enrollment change: Females, Aging, Metabolism, and Exercise (clinicaltrials.gov) - Dec 2, 2017
P=N/A, N=42, Completed, Sponsor: University of Colorado, Denver
Trial primary completion date: Dec 2017 --> Dec 2018 Active, not recruiting --> Completed | N=132 --> 42
- | progesterone / Generic mfg., leuprolide acetate for depot suspension / Generic mfg., estradiol valerate / Generic mfg.
Trial completion, Enrollment change, Trial initiation date, Trial primary completion date: Endometrial Receptivity Profile in Patients With Endometrial Proliferation Defects (clinicaltrials.gov) - Dec 2, 2017
P=N/A, N=1, Completed, Sponsor: Reproductive Medicine Associates of New Jersey
Active, not recruiting --> Completed | N=132 --> 42 Enrolling by invitation --> Completed | N=20 --> 1 | Initiation date: Nov 2014 --> Jul 2015 | Trial primary completion date: Dec 2017 --> Sep 2015
- ||| leuprolide acetate for depot suspension / Generic mfg.
Trial completion: Special Drug Use Surveillance of Leuplin PRO for Injection Kit 22.5 mg for "Prostate Cancer" (clinicaltrials.gov) - Nov 30, 2017
P=N/A, N=300, Completed, Sponsor: Takeda
Enrolling by invitation --> Completed | N=20 --> 1 | Initiation date: Nov 2014 --> Jul 2015 | Trial primary completion date: Dec 2017 --> Sep 2015 Active, not recruiting --> Completed
- | Climara (estradiol) / Bausch Health, Bayer
Trial completion, Enrollment change, Trial primary completion date: Vascular Mechanisms for the Effects of Loss of Ovarian Hormone Function on Cognition in Women (clinicaltrials.gov) - Nov 29, 2017
P=N/A, N=25, Completed, Sponsor: University of Colorado, Denver
Active, not recruiting --> Completed Recruiting --> Completed | N=34 --> 25 | Trial primary completion date: Dec 2018 --> Sep 2017
- ||||| Kisqali (ribociclib) / Novartis
Trial initiation date, Combination therapy, Metastases: CompLEEment-1: Study to Assess the Safety and Efficacy of Ribociclib (LEE011) in Combination With Letrozole for the Treatment of Men and Pre/Postmenopausal Women With HR+ HER2- aBC (clinicaltrials.gov) - Nov 14, 2017
P3, N=3775, Recruiting, Sponsor: Novartis Pharmaceuticals
Recruiting --> Completed | N=34 --> 25 | Trial primary completion date: Dec 2018 --> Sep 2017 Initiation date: Jul 2015 --> Jul 2016
- | Trial primary completion date: Neoadjuvant Chemo-endocrine Therapy Versus Chemotherapy Alone in ER-positive, HER2-negative Breast Cancer (clinicaltrials.gov) - Nov 13, 2017
P3, N=249, Completed, Sponsor: Fudan University
Initiation date: Jul 2015 --> Jul 2016 Trial primary completion date: Oct 2017 --> Feb 2017
- | Trial completion, Trial primary completion date: Neoadjuvant Chemo-endocrine Therapy Versus Chemotherapy Alone in ER-positive, HER2-negative Breast Cancer (clinicaltrials.gov) - Oct 31, 2017
P3, N=249, Completed, Sponsor: Fudan University
Trial primary completion date: Oct 2017 --> Feb 2017 Active, not recruiting --> Completed | Trial primary completion date: Dec 2016 --> Oct 2017
- | Enrollment closed, Trial primary completion date: Regulation of Cervical Mucus Secretion (clinicaltrials.gov) - Oct 27, 2017
P4, N=10, Active, not recruiting, Sponsor: Oregon Health and Science University
Active, not recruiting --> Completed | Trial primary completion date: Dec 2016 --> Oct 2017 Recruiting --> Active, not recruiting | Trial primary completion date: Apr 2017 --> Aug 2017
- | leuprolide acetate for depot suspension / Generic mfg.
New P4 trial: Leuprorelin Acetate DPS (Leuplin DPS) Treatment Quarterly in Patients With Central Precocious Puberty (clinicaltrials.gov) - Oct 20, 2017
P4, N=68, Recruiting, Sponsor: Jin Soon Hwang
- | Estrace topical (estradiol) / AbbVie, Estrace (estradiol) / AbbVie
Enrollment change: Neurophysiology of Postpartum Depression in an Experimental Model of Pregnancy and Parturition (clinicaltrials.gov) - Oct 17, 2017
P=N/A, N=36, Completed, Sponsor: University of North Carolina, Chapel Hill
Recruiting --> Active, not recruiting | Trial primary completion date: Apr 2017 --> Aug 2017 N=30 --> 36
- | Erleada (apalutamide) / J&J
New P2 trial: A Salvage Trial of AR Inhibition With ADT and Apalutamide With Radiation Therapy Followed by Docetaxel in Men With PSA Recurrent Prostate Cancer After Radical Prostatectomy (STARTAR) (clinicaltrials.gov) - Oct 17, 2017
P2, N=42, Not yet recruiting, Sponsor: Tian Zhang, MD
- | Keytruda (pembrolizumab) / Merck (MSD), nelitolimod (SD-101) / TriSalus Life Sci, UT MD Anderson Cancer Center
Trial suspension, Trial primary completion date, Combination therapy, PD(L)-1 Biomarker, Metastases: Pembrolizumab +/- SD-101 in Hormone-Na (clinicaltrials.gov) - Oct 16, 2017
P2, N=42, Suspended, Sponsor: Lawrence Fong
N=30 --> 36 Recruiting --> Suspended | Trial primary completion date: Apr 2019 --> Apr 2020
- | goserelin acetate / Generic mfg., leuprolide acetate for depot suspension / Generic mfg., bicalutamide / Generic mfg.
Enrollment closed, Surgery: RADICALS-HD: RADICALS - Radiotherapy and Androgen Deprivation In Combination After Local Surgery (clinicaltrials.gov) - Oct 13, 2017
P3, N=4236, Active, not recruiting, Sponsor: Medical Research Council
Recruiting --> Suspended | Trial primary completion date: Apr 2019 --> Apr 2020 Recruiting --> Active, not recruiting
- ||||||| leuprolide acetate for depot suspension / Generic mfg., zoledronic acid / Generic mfg.
Trial completion: TROG 03.04 - RADAR: RADAR Trial - Randomised Androgen Deprivation and Radiotherapy (clinicaltrials.gov) - Oct 12, 2017
P3, N=1071, Completed, Sponsor: Trans-Tasman Radiation Oncology Group (TROG)
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- | leuprolide acetate for depot suspension / Generic mfg.
Trial completion: Generation of Positive Biological Samples to Leuprolide Acetate for Doping Control (clinicaltrials.gov) - Oct 5, 2017
P1, N=5, Completed, Sponsor: Parc de Salut Mar
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | Erleada (apalutamide) / J&J
New P2 trial, Metastases: SOLAR: Systemic and Tumor-Directed Therapy for Oligometastatic Prostate Cancer (clinicaltrials.gov) - Sep 28, 2017
P2, N=28, Not yet recruiting, Sponsor: VA Office of Research and Development