alprazolam / Generic mfg. 
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  • ||||||||||  alprazolam / Generic mfg., methamphetamine / Generic mfg.
    Journal:  Risk-Based Newborn Drug Testing in a Setting With a Low Prevalence of Maternal Drug Use. (Pubmed Central) -  Apr 19, 2020   
    Performing universal newborn drug testing in the study population would have identified an additional 6 newborns who were exposed prenatally to tetrahydrocannabinol out of 600 who were additionally tested. In areas with a low prevalence of maternal drug use, universal testing may not be cost-effective.
  • ||||||||||  alprazolam / Generic mfg.
    Clinical, Journal:  Benzodiazepine Use Among Resident Doctors In Tertiary Care Hospital. (Pubmed Central) -  Apr 16, 2020   
    Because of the knowledge about medicines and tendency to self-treat, doctors are prone to BZD abuse. Doctors working in psychiatry are more likely to use BZD with Alprazolam the BZD of choice.
  • ||||||||||  citalopram / Generic mfg., venlafaxine / Generic mfg.
    Biomarker, Clinical, Journal:  Presence of pharmaceutical compounds, levels of biochemical biomarkers in seafood tissues and risk assessment for human health: Results from a case study in North-Western Spain. (Pubmed Central) -  Apr 10, 2020   
    A battery of biochemical biomarkers of effects (acetylcholinesterase, glutathione S-transferase; catalase, glutathione peroxidase and glutathione reductase enzymes activities and reduced/oxidized glutathione and malondialdehyde levels) was applied to samples of the study species with the aim of characterizing their basal levels and evaluating their suitability as a tool in the monitoring chronic exposure to environmental contaminants such as those analyzed in this study. According to the measured biomarkers, pod razor and cockles have the potential to be good bioindicator species, based on the observed among-site differences detected on acetylcholinesterase, glutathione S-transferase, catalase, glutathione peroxidase activities; reduced/oxidized glutathione and malondialdehyde levels.
  • ||||||||||  fluoxetine / Generic mfg.
    Not That Sweet Honeymoon: A Case of Proinsulinoma. (ENDOExpo) -  Apr 1, 2020 - Abstract #ENDO2020ENDO_3846;    
    Conclusion PI are predominantly benign neuroendocrine tumors that have the potential to cause symptomatic hypoglycemia. The patient's clinical manifestations were confused with an anxious syndrome and erotophobia, and these cases illustrate that the diagnosis of organic hypoglycemia can be challenging.
  • ||||||||||  Botox (onabotulinumtoxin A) / GSK, Allergan
    Review, Journal:  MDS evidence-based review of treatments for essential tremor. (Pubmed Central) -  Mar 29, 2020   
    MRI-guided focused ultrasound thalamotomy was, for the first time, assessed and was considered to be possibly useful. There is a need to improve study design in essential tremor and overcome the limitation of small sample sizes, cross-over studies, short-term follow-up studies, and use of nonvalidated clinical scales.
  • ||||||||||  clonazepam / Generic mfg., lorazepam / Generic mfg., alprazolam / Generic mfg.
    REM-Behavior Sleep Disorder Due to Post-Traumatic Stress Disorder: A Case Report in a Civilian Patient (PENNSYLVANIA CONVENTION CENTER, Hall D-E (200 Level), Area H) -  Mar 15, 2020 - Abstract #ATS2020ATS_10332;    
    In this patient, no other etiologies for his RBD were apparent over the 10 years of his illness, or 5+ years of medical evaluation.Clonazepam and high-dose melatonin were prescribed without relief of symptoms. He was ultimately referred for eye movement desensitization and reprocessing (EMDR) therapy, with results pending.
  • ||||||||||  ketamine / Generic mfg., alprazolam / Generic mfg., dizocilpine (MK801) / Merck (MSD)
    Preclinical, Journal:  Increased sensitivity to psychostimulants and GABAergic drugs in Lsamp-deficient mice. (Pubmed Central) -  Mar 12, 2020   
    More thorougly, sensitivity to GABA modulators (diazepam, alprazolam, ethanol, pentobarbital, TP003, and SL651498) was assessed...No gross differences in sensitivity to NMDA receptor modulators were observed. Thus, as the lack of Lsamp gene leads to widespread imbalances in major neurotransmitter systems in the brain accompanied by remarkable changes in behavioural phenotype as well, Lsamp-deficient mice are a promising model for mimicking psychiatric disorders.
  • ||||||||||  flumazenil / Generic mfg., alprazolam / Generic mfg.
    Preclinical, Journal:  GABA/benzodiazepine receptors in the dorsal periaqueductal gray mediate the panicolytic but not the anxiolytic effect of alprazolam in rats. (Pubmed Central) -  Mar 10, 2020   
    There is also evidence that this midbrain area is critically involved in mediation of the panicolytic effect of antidepressants, which with high potency benzodiazepines (e.g. alprazolam and clonazepam) are first line treatment for PD...We here investigated the consequences of blocking GABA or benzodiazepine receptors within the dPAG, with bicuculline (5 pmol) and flumazenil (80 nmol), respectively, on the panicolytic and anxiolytic effects of alprazolam (4 mg/kg)...Altogether, our findings show the involvement of GABA/benzodiazepine receptors of the dPAG in the panicolytic, but not the anxiolytic effect caused by alprazolam. They also implicate the dPAG as the fulcrum of the effects of different classes of clinically effective antipanic drugs.
  • ||||||||||  alprazolam / Generic mfg.
    [VIRTUAL] RISK ESTIMATION BY BOOSTED DOUBLY ROBUST METHOD () -  Mar 8, 2020 - Abstract #ISPOR2020ISPOR_452;    
    As an example, we examined the established association between diazepam, a long-acting benzodiazepine, and alprazolam, a short-acting benzodiazepine, and risk of injury using BDR and conventional adjustment methods including no adjustment, Poisson regression, propensity scoring using logistic regression (LPS), and high dimensional propensity scoring (HDPS)... BDR improves balance in the pre-treatment covariates, reduces bias and reduces variance and deserves consideration in outcomes research studies.
  • ||||||||||  alprazolam / Generic mfg.
    Clinical, Journal:  Femoral blood concentrations of flualprazolam in 33 postmortem cases. (Pubmed Central) -  Feb 21, 2020   
    Flualprazolam is a novel designer benzodiazepine, structurally related to alprazolam, flubromazolam and triazolam...Combining the resources of two countries in which all post-mortem toxicology is centralised provided a more comprehensive insight into the toxicology of flualprazolam. Research on novel psychoactive substances, such as flualprazolam, is required in order to be able to provide scientific evidence on the risks of these new substances for drug administration and potential users.
  • ||||||||||  alprazolam / Generic mfg.
    Review, Journal:  A structural perspective on GABA receptor pharmacology. (Pubmed Central) -  Feb 20, 2020   
    This effort culminated with the high-resolution structural analysis of an intact, full-length human heteropentameric receptor, α1β3γ2, in a lipid bilayer and in complex with small molecule ligands including the commonly used benzodiazepines diazepam (Valium) and alprazolam (Xanax). These structures reveal multiple aspects of receptor activation and provide a path for rational design of subunit-specific GABA receptor modulators.
  • ||||||||||  [VIRTUAL] Capgras Syndrome (All Screens in Poster Area) -  Feb 20, 2020 - Abstract #EPA2020EPA_2048;    
    Finally she is hospitalized for a week starting treatment with risperidone 3mg... According to the literature reviewed, several etiological theories are proposed: a possible disconnection between the limbic regions (responsible for emotions) and the occipito-temporal cortex (facial recognition); lesions in right frontoparietal areas; or failures in information processing.
  • ||||||||||  alprazolam / Generic mfg., methamphetamine / Generic mfg.
    [VIRTUAL] Suspicion of chemical submission in a hospital emergency department: a case report (All Screens in Poster Area) -  Feb 20, 2020 - Abstract #EPA2020EPA_1912;    
    Occasionally, it may be confused with any psychotic disorder. To avoid this, it is necessary to verify the story with a toxicological analysis and, if in doubt, conduct an interconsultation to psychiatry department.
  • ||||||||||  quetiapine / Generic mfg.
    [VIRTUAL] Burning mouth syndrome associated to Quetiapine treatment. (All Screens in Poster Area) -  Feb 20, 2020 - Abstract #EPA2020EPA_1515;    
    It is a multifactorial pathology. In many cases, correcting or eliminating these etiologic agents does not improve or stop the initial symptoms, but sometimes, it does.
  • ||||||||||  sertraline / Generic mfg., quetiapine / Generic mfg.
    [VIRTUAL] A case of hysteric psychosis symptomed with childish behaviors (All Screens in Poster Area) -  Feb 20, 2020 - Abstract #EPA2020EPA_1388;    
    In this case, it is interesting that the regression progresses to crawling. The diagnosis of adult baby syndrome is becoming increasingly worthy of discussion.
  • ||||||||||  quetiapine / Generic mfg.
    [VIRTUAL] What your eyes don't see: a case report of Charles Bonnet syndrome (All Screens in Poster Area) -  Feb 20, 2020 - Abstract #EPA2020EPA_1176;    
    He was treated with quetiapine 50mg id and alprazolam 0.25 mg 1/2 id, which was suspended few weeks later due to intolerance. It is important to know and be aware of these situations, which can be easily confused with delirium or dementia.
  • ||||||||||  clonazepam / Generic mfg., alprazolam / Generic mfg.
    Journal, Interview:  Psychosomatic medicine around the world. Interview (Pubmed Central) -  Feb 14, 2020   
    Taking into account the risks of adverse effects, interactions and the inclusion of some of these drugs among those that should not be prescribed among older adults, the high prescription rate of some of these drugs is alarming. It is necessary to develop strategies among general practitioners, specialists and also among the general population in order to reduce the prescription of psychotropic drugs.
  • ||||||||||  alprazolam / Generic mfg.
    Analysis of designer benzodiazepine flualprazolam and its in vitro metabolites using GC-MS (Exhibit Hall A, Pennsylvania Convention Center) -  Feb 13, 2020 - Abstract #ACSSp2020ACS_Sp_3666;    
    Flualprazolam, an analogue of the 1,4-benzodiazepine alprazolam, is of notable interest due to the scarcity of published literature on its physiology and metabolism...Phase I metabolism is replicated through the use of pooled human liver microsomes (pHLM), and a method was developed for analysis by GC-MS, instead of the more common HPLC. The method developed for the in vitro experiments and proposed primary phase I metabolites of flualprazolam are presented.