| mupirocin / Generic mfg. |
2015-002223-25: Eradication of methicillin-susceptible Staphylococcus aureus nasal carriage in patients undergoing dialysis: can fusidic acid be used as an alternative to mupirocin? |
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| Ongoing | 4 | 140 | Europe | Fucidin 2% (sodium fusidate), Bactroban 2% (mupirocin), Nasal ointment, FUCIDIN 2%, ointment, BACTROBAN 2% Nasal ointment | Ghent University Hospital, AZ Sint Lucas | persistent nasal Staphylococcus aureus carriage, Staphylococcus aureus carriage, Diseases [C] - Bacterial Infections and Mycoses [C01] | | | | |
2010-022701-17: Reduction of surgical-site infection in hip and knee replacement: the influence of perioperative nasal ointment with antibiotics and soap with alcohol solotion in decreasing the amount of infections. |
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| Ongoing | 4 | 12000 | Europe | mupirocin, hibiscrub, Nasal ointment, Cutaneous foam, Mupirocine neuszalf 2% 20mg/ml, Chloorhexidinedigluconaat Zeep oplossing 40mg/ml | Isala, Isala | osteoarthritis of hip and knee, prevention of surgical site infections after arthroplasty, patients with osteoarthritis from the hip or knee, whom underwent hip or knee replacment. lookin at the infectionrate one years after surgery and the influence of decolonization of s. aureus bacteria, Diseases [C] - Bacterial Infections and Mycoses [C01] | | | | |
2006-006928-18: Randomised trial of Prontosan wound gel for prevention of exit site infection in peritoneal dialysis patients |
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| Ongoing | 4 | | Europe | Mupirocin ointment, not known, Bactroban, Bactroban | Barts and The London NHS Trust | Peritoneal dialysis patients and their peritoneal dialysis catheter exit site care. | | | | |
2018-002119-81: Interaction between S. aureus and other bacteria in the nose Wisselwerking tussen S. aureus en andere bacteriën in de neus |
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| Ongoing | 4 | 175 | Europe | Nasal ointment, Cutaneous solution, Bactroban 2% Neuszalf 20 mg/g, Hibiscrub | Erasmus MC, ZonMW | S. aureus carriage S. aureus dragerschap, S. aureus carriage S. aureus dragerschap, Body processes [G] - Microbiological Phenomena [G06] | | | | |
2018-002913-37: Clinical study comparing the action and the safety of two approved drugs for nasal application,containing the same active substance - mupirocin. Клинично изпитване, сравняващо действието и безопасността на две разрешени за употреба лекарства за приложение в носа, съдържащи една и съща активна съставка - мупироцин. |
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| Not yet recruiting | 4 | 260 | Europe | Nasal ointment, MupiroNasal 20mg/g, nasal ointment, Bactroban 2%, nasal ointment | Antibiotic-Razgrad AD, Antibiotic-Razgrad AD | For elimination/eradication of nasal carriage of staphylococci, including methicillin-resistant Staphylococcus aureus (MRSA) За елиминиране/ликвидиране на назално носителство на стафилококи, включително метицилин-резистентен Staphylococcus aureus (MRSA), Asymptomatic presence of Staphylococcus aureus bacteria in the nose in clinically healthy people. Безсимптомно наличие на бактерии Staphylococcus aureus в носа при клинично здрави лица., Diseases [C] - Bacterial Infections and Mycoses [C01] | | | | |
ChiCTR1800017248: A combination of mupirocin and acidic fibroblast growth factor for nipple fissure and nipple pain in breastfeeding women: a randomised controlled trial |
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| Not yet recruiting | 4 | 120 | | mupirocin plus aFGF ;mupirocin plus aFGF placebo | Tianjin Central Hospital of Gynecology Obstetrics; Level of the institution：, Tianjin Education Commission 'Innovative Team Training Program' (No. TD13-5047) | nipple fissure and nipple pain in breastfeeding women | | | | |
| Recruiting | 4 | 850 | Europe | Decolonization, No decolonization | Centre Hospitalier Universitaire de Saint Etienne, Ministry of Health, France | Hemodialysis Patients | 10/24 | 10/24 | | |
| Active, not recruiting | 4 | 835 | US | Chlorhexidine, Hibiclens, Mupirocin, Bactroban, Household cleaning | Washington University School of Medicine | Skin and Subcutaneous Tissue Bacterial Infections, Staphylococcus Aureus, MRSA - Methicillin Resistant Staphylococcus Aureus Infection | 09/24 | 12/24 | | |
NCT03140423: Mupirocin-Iodophor ICU Decolonization Swap Out Trial |
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| Completed | 4 | 353323 | US | Arm 1. Routine Care (Mupirocin/CHG), Arm 2. Iodophor/CHG Decolonization | Harvard Pilgrim Health Care, Hospital Corporation of America, University of California, Irvine, University of Massachusetts, Amherst, Rush University, Centers for Disease Control and Prevention | Staphylococcus Aureus | 11/23 | 11/23 | | |
| Recruiting | 4 | 100 | US | Mupirocin + Nozin + chlorhexidine gluconate, Bactroban + Nozin + Hibiclens, Education + Household supplies | Johns Hopkins Bloomberg School of Public Health, National Institute of General Medical Sciences (NIGMS) | Staphylococcus Aureus Infection | 01/25 | 01/26 | | |
NCT06397781: Effect of S. Aureus Skin Decolonization on Disease Severity in Atopic Dermatitis Patients |
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| Not yet recruiting | 4 | 100 | US | Skin Cleanser Combination No.1 | Boston Children's Hospital | Atopic Dermatitis | 12/28 | 12/28 | | |
| Recruiting | 4 | 2700 | US | 4% Chlorhexidine Gluconate, 2% Mupirocin, Soap Without Antiseptic Properties (Placebo), Placebo Nasal Ointment | University of California, Irvine, University of California, Davis, University of California, San Francisco, University of Massachusetts, Amherst, Hoag Memorial Hospital Presbyterian | Surgical Site Infection | 12/27 | 12/28 | | |
2008-001204-23: Estudio comparativo de mupirocina versus acido fusidico tópico en la erradicación de portadores nasales de Staphylococcus aureus en pacientes con insuficiencia renal crónica en hemodiálisis por cateter permanente |
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| Ongoing | 3 | 80 | Europe | FUCIDINE POMADA, BACTROBAN NASAL, POMADA, FUCIDINE POMADA, BACTROBAN NASAL, pomada, FUCIDINE POMADA, BACTROBAN NASAL, pomada | Dra. Beatriz Sanchez Sobrino | Pacientes con insuficiencia renal crónica estadio 5 en Hemodialisis que se encuentren realizando la técnica mediante un acceso vascular tipo catéter central permanente tunelizado portadores nasales de Pacientes con insuficiencia renal crónica estadio 5 en Hemodialisis que se encuentren realizando la técnica mediante un acceso vascular tipo catéter central permanente tunelizado portadores nasales de Staphylococcus aureus. | | | | |
2009-017398-39: Randomised double-blind, vehicle controlled dosing frequency study of HT61 1% gel applied to the anterior nares plus chlorhexidine body and hair washes in subjects with nasal carriage of Staphylococcus aureus and comparison with mupirocin |
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| Ongoing | 3 | 56 | Europe | HT61 1% gel, Bactroban Nasal Ointment, Cepton, HY50A, Bactroban Nasal, Bactroban Nasal | Helperby Thearapeutics Ltd | Nasal carriage of Staphylococcus aures (including MRSA) | | | | |
NCT05893810: Bacterial Decolonization to Prevent Radiation-induced Oral Mucositis |
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| Recruiting | 3 | 176 | RoW | Mupirocin Ointment | Jiangxi Provincial Cancer Hospital | Nasopharyngeal Carcinoma, Radiation-induced Oral Mucositis, Bacterial Colonization, Quality of Life | 04/24 | 12/24 | | |
| Recruiting | 3 | 80 | Europe | Clindamycin, Placebo | Hvidovre University Hospital | MRSA, MRSA Colonization | 09/32 | 09/32 | | |
ACTRN12611000994987: Effect of Mupirocin in patients with refractory chronic rhinosinusitis - A prospective, randomised double-blinded controlled trial |
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| Recruiting | 2/3 | 40 | | | The Queen Elizabeth Hospital, Department of Otolaryngology Head & Neck Surgery | Chronic Rhinosinusitis | | | | |
NCT05874219: Mupirocin 2% Ointment Vs Spray Antibiotics on Temporary Hemodialysis Catheter |
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| Completed | 2/3 | 150 | RoW | Local antibiotic spray Neomycin sulphate 165,000 IU + Bacitracin zinc 12,500 IU, BIVATRACIN, Mupirocin 2% ointment | Future University in Egypt | Hemodialysis Complication, Hemodialysis Catheter Infection | 05/23 | 05/23 | | |
2005-002698-65: A randomised clinical trial comparing safety and efficacy of topical preparations for the eradication of methicillin resistant staphylococcus aureus (MRSA) compared with a novel preparation based on a specific blend of essential oils in surgical oncology patients. |
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| Ongoing | 2 | 110 | Europe | protocol, EOB_71, Aquasept skin cleanser, Bactroban nasal ointment, corsodyl mouthwash, Bodywash_71, Nasal gel_71, Inhalation_71, | Christie Hospital NHS Trust | Colonisation with methicillin resistant Staphylococcus Aureus (MRSA) | | | | |
| Recruiting | 2 | 42 | US | Trimethoprim Sulfamethoxazole (TMP/SMX), Septra, Bactrim, Minocycline, Cleeravue-M, Dynacin, Minocin, Solodyn, Vectrin, Mupirocin, Bactroban, Centany, Chlorhexidine Gluconate, Dyna-Hex, Environmental Decontamination, Sani-Cloth wipes | University of North Carolina, Chapel Hill, University of Washington, Cook Children's Medical Center, Indiana University, University of Michigan, University of Texas Southwestern Medical Center, St. Louis Children's Hospital | Cystic Fibrosis | 08/25 | 12/25 | | |
NCT05505214: Topical Steroids & Bacterial Decolonization for Radiation Dermatitis |
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| Withdrawn | 2 | 216 | US | Bacterial decolonization, Mometasone furoate 0.1% cream, Bacterial decolonization and Mometasone furoate 0.1% cream | Montefiore Medical Center | Radiation Dermatitis | 09/25 | 09/25 | | |
ACTRN12623000011684: A double-blinded randomised control human clinical trial evaluating the safety and effectiveness of colloidal silver sinonasal rinse versus standard of care on post-operative symptomatic outcomes in the treatment of Chronic Rhinosinusitis in adults. |
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| Recruiting | 1/2 | 44 | | | Central Adelaide Local Health Network, The University of Adelaide, The Queen Elizabeth Hospital | chronic rhinosinusitis | | | | |
ACTRN12623000253606: The Australasian Malignant PLeural Effusion (AMPLE)-4 Trial: Topical Antibiotic Prophylaxis for Infections of Indwelling Pleural Catheters in Patients with Malignant Pleural Effusions |
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| Recruiting | 1/2 | 418 | | | Institute for Respiratory Health, WA Cancer Council | Malignant pleural effusion | | | | |
NCT04438174: Processed Amniotic Fluid (pAF) for the Treatment of Chronic Wounds |
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| Terminated | 1/2 | 1 | US | Processed Amniotic Fluid, Processed Amniotic Fluids (pAF), Human Amniotic Fluids (hAF), Standard of Care Wound Treatment Regimen | University of Utah | Wounds and Injuries | 03/23 | 03/23 | | |
ACTRN12624000076572: Clindamycin and bacterial load reduction as prophylaxis for surgical site infection after below-knee flap and graft procedures: a trial protocol. |
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| Recruiting | 1 | 155 | | | James Cook University, James Cook University | Skin Cancer, Surgical site infection | | | | |
| Completed | 1 | 40 | RoW | Monolaurin, Treatment Group, Mupirocin ointment, Control | Victoriano Luna Medical Center | Bacterial Infections | 06/23 | 07/23 | | |
| Recruiting | 1 | 40 | Europe | Mupirocin (50 mg), Bactroban, Mupirocin (500 mg), blood samples after Single dose part, nasal swab after Single dose part, intranasal concentrations, Collection of urine after Single dose part, nasal swab during Repeated dose part, Collection of urine during Repeated dose part, nasal swab after Repeated dose part | Centre Hospitalier Universitaire de Saint Etienne | Healthy, Staphylococcus Aureus Infection | 11/24 | 03/25 | | |
ACTRN12624000877583: NSW Government-Sponsored Clinical Trial: Management of Dermatology Conditions by Community Pharmacists |
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| Recruiting | N/A | 22857 | | | The University of Newcastle , NSW Government | Herpes Zoster, Acute Exacerbations of Mild Plaque Psoriasis, Mild to Moderate Atopic Dermatitis, Impetigo | | | | |
ChiCTR-IPR-17012671: The comparative study of Chlorhexidine Gluconate and Mupirocin as decolonization agent of Staphylococcus aureus in nasal vestibular among health care workers of intensive care unit |
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| Recruiting | N/A | 60 | | Decolonization using 0.2% Chlorhexidine Gluconate ointment ;Decolonization using 2% Mupirocin ointment | Department of Critical Care Medicine, Qilu Hospital of Shandong University; Qilu Hospital of Shandong University, National natural science foundation of China (81501786) | Staphylococcus aureus colonization in nasal vestibular among health care workers of intensive care unit | | | | |
NCT05839158: Evaluation of the Effect of HFMT in Promoting Donor-site Wound Healing |
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| Completed | N/A | 100 | RoW | HFMT cell suspension, Mupirocin ointment | Nanfang Hospital, Southern Medical University | Wound Heal | 12/22 | 12/22 | | |
NCT06291181: Studying the Distribution of Accessory Gene Regulator (Agr) Quorum Sensing System and the Prevalence of Linezolid and Mupirocin Resistance in Biofilm Producer/Non Producer Staphylococcus Aureus in Sohag University Hospitals |
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| Completed | N/A | 265 | RoW | antibiotic sensitivity test | Sohag University | Staphylococcus Aureus | 06/23 | 06/23 | | |
NCT05251584: Effects of Topical Gentamicin on the Prevention of Peritoneal Dialysis Related Infection |
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| Recruiting | N/A | 60 | RoW | Mupirocin, BACIDAL, Gentamicin, GENTREX | Phramongkutklao College of Medicine and Hospital, Silpakorn University Faculty of Pharmacy | Peritoneal Dialysis-related Infection | 03/23 | 05/23 | | |
ChiCTR2000033786: Effect and mechanism of micro negative pressure therapy on burn wound: a randomized controlled trial. |
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| Recruiting | N/A | 40 | | Dressing by Mupirocin Ointment ;Dressing by MNPDD | The 903rd Hospital of PLA; Level of the institution：, Natural Fund Committee of Zhejiang Provincial | Burn | | | | |
| Completed | N/A | 30 | Europe | No dressing | University Hospital, Caen | Peritoneal Dialysis | 06/23 | 08/23 | | |
ChiCTR2300071023: A multi-center clinical study on the treatment of perianal abscess in infants and toddlers by Gu's Surgical JInhuang Ointment |
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| Recruiting | N/A | 122 | | Apply the JInhuang Ointment externally ;Apply the Mupirocin Ointment externally | Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine; Shanghai Evidence-based Medicine Research Center of Traditional Chinese Medicine, Shanghai Evidence-based Medicine Research Center of Traditional Chinese Medicine: Project of "Construction of TCM Clinical Research Highland" in Shanghai Three-year Action Plan of Traditional Chinese Medicine | perianal abscess of Infants and toddlers | | | | |
NCT06378359: Effectiveness of Screening and Decolonization of S. Aureus to Prevent S. Aureus Surgical Site Infections in Surgery Outpatients |
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| Recruiting | N/A | 250 | US | Screening and decolonization for SA carriers with the 3 drug bundle, No screening for SA, no screening, Nasal povidone-iodine on surgery day plus 2 CHG pre-op showers without screening., Nasal alcohol gel on surgery day plus 2 CHG pre-op showers without screening | University of Minnesota | Staphylococcus Aureus Colonization, Surgical Site Infections, Healthcare Associated Infections | 12/25 | 12/26 | | |
| Recruiting | N/A | 20 | US | Mupirocin, Bactroban, Chlorhexidine baths, CHG cloths | Duke University, Bristol-Myers Squibb | Bacterial Colonization | 10/24 | 06/25 | | |
ChiCTR2400085012: Clinical effects of photodynamic therapy with Ondapench photosensitive antibacterial powder as photosensitiser compared with mupirocin ointment in the treatment of bacterial skin infections |
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| Recruiting | N/A | 20 | | Red light irradiation + Ondapench photosensitive antibacterial powder; Red light irradiation + Mupirocin ointment | Xiangya Hospital of Central South University; Xiangya Hospital of Central South University, Guilin Hui Ang Biochemical Pharmaceutical Co.,Ltd. | Bacterial skin infection | | | | |
ACTRN12613000300774: The effect of supported guideline implementation in a network of renal units on rates of infection in their peritoneal dialysis patients |
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| Not yet recruiting | N/A | 270 | | | Assoc Prof David Mudge, KHA-CARI Guidelines
Kidney Health Australia | Clinical practice variation, Effect of active guideline implementation, Prevention of peritoneal dialysis-related infection
, Identify barriers and enablers to guideline implementation, Kidney disease | | | | |
ACTRN12621000993897: Investigating the ability of topical probiotics to change the bacterial profile of actinic keratosis from a detrimental to healthy composition |
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| Completed | N/A | 40 | | | University of Queensland , NHMRC | Actinic Keratosis, Bacterial population on actinic keratosis | | | | |
