risperidone / Generic mfg. 
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  • ||||||||||  Choreoballism due to Bisphosphonate-Induced Antiphospholipid Syndrome: A Case Report (Poster Hall (Exhibit Hall A)) -  Aug 9, 2024 - Abstract #MDSCongress2024MDS_Congress_1511;    
    There is only one other report of a movement disorder following bisphosphonate administration which was ultimately attributed to hypocalcemia [4]. Increasing awareness can inform providers to recognize these rare reactions.
  • ||||||||||  Austedo (deutetrabenazine) / Teva
    Treatment of Severe Tardive Syndrome with Pallidotomy: A Case Report (Poster Hall (Exhibit Hall A)) -  Aug 9, 2024 - Abstract #MDSCongress2024MDS_Congress_1281;    
    This case provides evidence for the safety and utility of MRI-guided LITT pallidotomy in treatment of refractory tardive syndrome. This procedure should be considered for those patients with a contradiction for implantation of DBS hardware.
  • ||||||||||  risperidone / Generic mfg.
    Tardive Dystonia Following Risperidone Treatment : A Case Report and Therapeutic Approach (Poster Hall (Exhibit Hall A)) -  Aug 9, 2024 - Abstract #MDSCongress2024MDS_Congress_655;    
    This case highlights the importance of recognizing SGAs like risperidone, as a systemic contributor of the development of focal dystonia, particularly tardive dystonia, due to its impact on the dopamine system. Early detection and appropriate management, including the use of botulinum toxin therapy and antipsychotic modifications, can lead to significant improvement in patient outcomes.
  • ||||||||||  Comorbidity of schizophrenia and Parkinson's disease: a clinical case report (Poster Hall (Exhibit Hall A)) -  Aug 9, 2024 - Abstract #MDSCongress2024MDS_Congress_615;    
    Because of the overlap in clinical manifestations between Parkinson's disease and schizophrenia, differential diagnosis of these diseases is often extremely difficult. Modern literature suggests that these disorders are etiologically and pathogenetically united, as this clinical example illustrates.
  • ||||||||||  fluoxetine / Generic mfg.
    Preclinical, Journal:  Fluoxetine Rescues Excessive Myelin Formation and Psychological Behaviors in a Murine PTSD Model. (Pubmed Central) -  Aug 7, 2024   
    Further mechanistic experiments revealed that fluoxetine could directly interfere with oligodendroglial differentiation by upregulating Wnt signaling. Our data demonstrated the correlation between PTSD and abnormal myelination, suggesting that the oligodendroglial lineage could be a target for PTSD treatment.
  • ||||||||||  risperidone / Generic mfg.
    Journal:  Detection of new metabolites of risperidone in the solid tissues and body fluids obtained from two cadavers by high resolution tandem mass spectrometry. (Pubmed Central) -  Aug 4, 2024   
    For example, the peak ratios of c-Ris against the parent Ris in the kidney and blood were as high as 3.9 and 3.6 in cadaver 1; and 7.0 and 7.9 in cadaver 2, respectively. In addition to the previously reported six metabolites, five new metabolites such as dehydrogenated-Ris, 7-keto-Ris and three benzisoxazole ring-cleaved metabolites were disclosed in the present work, and the pathways for the totally eleven metabolites detected in human solid tissues and body fluids have also been proposed, because such pathways were neither reported nor discussed previously.
  • ||||||||||  risperidone / Generic mfg.
    TARDIVE DYSKINESIA OF THE VOCAL CORDS: AN UNCOMMON CAUSE OF TACHYPNEA (Convention Center Exhibit Hall: Poster Area 2) -  Jul 31, 2024 - Abstract #CHEST2024CHEST_5277;    
    CASE PRESENTATION: A 65-year-old female with a history of chronic obstructive pulmonary disease, major depressive disorder with psychotic features on risperidone, tardive dyskinesia (TD) secondary to medication, and dysphagia presented to her local emergency department (ED) for worsening shortness of breath...If patients with TD present with stridor, dyspnea on exertion, interrupted speech, or other concerning respiratory symptoms, vocal cord dysfunction from TD should be considered, although it is a diagnosis of exclusion. The treatment for vocal cord dysfunction due to TD is botulinum toxin injections every 3-6 months.
  • ||||||||||  risperidone / Generic mfg.
    Journal:  A hybrid model for predicting response to risperidone after first episode of psychosis. (Pubmed Central) -  Jul 29, 2024   
    The hybrid model, which included duration of untreated psychosis, Clinical Global Impression-Severity scale scores, age, cannabis use, and 406 SNVs, showed the best performance (balanced accuracy: 72.9% [CI 0.62-0.84] - RF algorithm). A hybrid model, including clinical and genetic predictors, can provide enhanced predictions of response to antipsychotic treatment.
  • ||||||||||  ketamine / Generic mfg.
    Preclinical, Journal:  The antipsychotic potential of Salix Mucronata on ketamine-induced rats. (Pubmed Central) -  Jul 23, 2024   
    Dopamine and acetylcholine concentration levels were high in groups which received risperidone and S. mucronata. These findings highlight that the antipsychotic potential of S. mucronata is similar to risperidone.
  • ||||||||||  lithium carbonate ER / Generic mfg., iloperidone / Generic mfg.
    Journal:  Iloperidone (Fanapt) - a new indication for bipolar disorder. (Pubmed Central) -  Jul 15, 2024   
    In addition, the present results support the potential of crocins as an adjunctive drug for the therapy of schizophrenia. No abstract available
  • ||||||||||  Review, Journal:  The Effect of Neuropsychiatric Drugs on the Oxidation-Reduction Balance in Therapy. (Pubmed Central) -  Jul 13, 2024   
    They are starting with those proving their protective effect and ending with those confirming disturbances in the oxidation-reduction balance. The presented publication reviews the state of knowledge on the role of oxidative stress in the most frequently used therapies for neuropsychiatric diseases using first- and second-generation antipsychotic drugs, i.e., haloperidol, clozapine, risperidone, olanzapine, quetiapine, or aripiprazole, mood stabilizers: lithium, carbamazepine, valproic acid, oxcarbazepine, and antidepressants: citalopram, sertraline, and venlafaxine, along with a brief pharmacological characteristic, preclinical and clinical studies effects.
  • ||||||||||  risperidone / Generic mfg., olanzapine / Generic mfg.
    Journal:  Rare presentation of Kl (Pubmed Central) -  Jul 8, 2024   
    Numerous neurological conditions can cause KBS. Symptomatic treatment is the mainstream treatment currently for KBS.[3] While different differential diagnoses are present, neurologists, psychiatrists, neurosurgeons, and radiologists should collaborate and be vigilant for the diagnosis of KBS, especially with the presence of one of its etiologies.
  • ||||||||||  Review, Journal:  Pharmacological treatment of posttraumatic stress disorder (Pubmed Central) -  Jul 3, 2024   
    Venlafaxine, in particular, has shown good effectiveness in studies, whereas risperidone has shown lower effectiveness in augmentation...Treatment of trauma-related nightmares can be attempted with doxazosin or clonidine. In contrast, there are limited empirical data available for sleep disorders associated with PTSD, but the pharmacological treatment of insomnia can provide some guidance.
  • ||||||||||  Biomarker, Journal:  Pharmacogenetic Testing or Therapeutic Drug Monitoring: A Quantitative Framework. (Pubmed Central) -  Jul 3, 2024   
    However, genotype prevalence and the relative influence of genotypes on the PK, as well as the ability of TDM to accurately estimate AUC with a limited number of samples, had an impact. The results could be used to support clinical decision making when considering other factors, such as the probability for severe side effects.
  • ||||||||||  aripiprazole / Generic mfg., risperidone / Generic mfg., olanzapine / Generic mfg.
    Journal:  Effects of atypical antipsychotics on serum asprosin level and other metabolic parameters in patients with schizophrenia. (Pubmed Central) -  Jun 28, 2024   
    Our cross-sectional study highlights the association between elevated asprosin levels, weight gain, and metabolic disorders in patients treated with olanzapine and risperidone. Given the bidirectional nature of the relationship between serum asprosin levels and these metabolic disturbances, further research is warranted to elucidate potential causative pathways.
  • ||||||||||  risperidone / Generic mfg.
    Journal:  Risperidone-Loaded Nasal Thermosensitive Polymeric Micelles: Quality by Design-Based Formulation Study. (Pubmed Central) -  Jun 27, 2024   
    The model formulations showed a rapid, burst-like drug release profile in vitro, accompanied by a quick and high permeation rate at nasal conditions. Overall, the Quality by Design-based risk assessment process led to the development of an advanced drug delivery system capable of administering risperidone through the nasal cavity.
  • ||||||||||  clozapine / Generic mfg.
    Journal:  Investigating in VigiBase (Pubmed Central) -  Jun 26, 2024   
    During the first week, pneumonia was associated with: 1) very high titration doses, 2) very small doses in Parkinson's disease and 3) Japan vs other countries. In clozapine-treated patients: 1) at least 30% of pneumonia cases may be aspiration pneumonia, 2) stopping some co-medications may decrease the risk of aspiration pneumonia, 3) average lethality in pneumonia was 45% but may be around 75% in geriatric patients in long-term treatment, and 4) safer titrations may sometimes require 5-mg tablets.
  • ||||||||||  Seizalam (midazolam intramuscular) / Pfizer
    Perioperative Considerations and Management of Neurodiverse Patients (126A) -  Jun 25, 2024 - Abstract #ASA2024ASA_1585;    
    He takes risperidone every morning for behavior, which helps keep him calm most of the morning...Additionally, he had an intramuscular injection following the midazolam which he had to be restrained for...When would you bring back the guardians? After the patient wakes up or prior to?
  • ||||||||||  Seizalam (midazolam intramuscular) / Pfizer
    Perioperative Considerations and Management of Neurodiverse Patients (126A) -  Jun 25, 2024 - Abstract #ASA2024ASA_1066;    
    He takes risperidone every morning for behavior, which helps keep him calm most of the morning...Additionally, he had an intramuscular injection following the midazolam which he had to be restrained for...When would you bring back the guardians? After the patient wakes up or prior to?
  • ||||||||||  lithium carbonate ER / Generic mfg.
    Journal, Gold standard:  Lithium, the gold standard drug for bipolar disorder: analysis of current clinical studies. (Pubmed Central) -  Jun 25, 2024   
    Lithium was superior to aripiprazole, valproic acid, and quetiapine in terms of improving manic symptoms...Only the add-on therapy with sertraline led to a higher rate of study discontinuations than lithium-monotherapy...However, risperidone and quetiapine were superior to lithium in some aspects, which is why these drugs should be considered as an alternative treatment option for children. Collectively, current clinical studies highlight the relevance of lithium in the treatment of bipolar disorder.