risperidone / Generic mfg. 
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  • ||||||||||  risperidone / Generic mfg., olanzapine / Generic mfg., amantadine / Generic mfg.
    Journal:  A Case Series of Delusional Infestation in (Pubmed Central) -  Jun 21, 2024   
    The second experienced gradual resolution of DI with risperidone in the setting of iron repletion and amantadine discontinuation, although her other psychotic symptoms remained. These cases shed light on an uncommon condition and may help guide understanding of the most effective treatment for it.
  • ||||||||||  clozapine / Generic mfg.
    Journal:  Functional coupling between MC4R and Kir7.1 contributes to clozapine-induced hyperphagia. (Pubmed Central) -  Jun 19, 2024   
    Deletion of Kir7.1 in Mc4r-Cre neurons prevents clozapine-induced weight gain, while treatment with a selective Kir7.1 blocker mitigates overeating in clozapine-fed mice. Our findings unveil a molecular pathway underlying the effect of APDs on feeding behavior and suggest its potential as a therapeutic target.
  • ||||||||||  memantine / Generic mfg., perospirone / Generic mfg.
    Journal:  Delirium due to Trousseau syndrome treated with memantine and perospirone: A case report. (Pubmed Central) -  Jun 13, 2024   
    We report the first case of Trousseau syndrome delirium treated by memantine used with perospirone. Although further studies are needed, memantine and perospirone might be candidates for the management of psychiatric symptoms associated with Trousseau syndrome.
  • ||||||||||  risperidone / Generic mfg.
    Journal:  Association between psychotropics use and occurrence of falls in hospitalized patients: A matched case-control study. (Pubmed Central) -  Jun 13, 2024   
    The multivariable conditional logistic regression model showed a significant association between the use of risperidone (odds ratio [OR]?=?3.730; 95% confidence interval [CI]?=?1.229-11.325) and flunitrazepam (OR?=?4.120; 95% CI?=?1.105-15.364) and an increased OR of falls among hospitalized patients. The use of risperidone and flunitrazepam were identified as risk factors for falls among hospitalized patients.
  • ||||||||||  lithium carbonate ER / Generic mfg.
    Journal:  Pharmacological Mechanism of Herbal Interventions for Bipolar Disorder. (Pubmed Central) -  Jun 7, 2024   
    Though different treatments are available, like lithium, risperidone, valproic acid, etc., which are widely used, they come with certain limitations, including narrow therapeutic index, hypothyroidism, weight gain, extrapyramidal symptoms, etc. The interest in herbal- based treatments for bipolar disorder arises from the desire for alternative, potentially more natural, and holistic approaches with fewer side effects. The current review focuses on the potential effects of herbal drugs and their derivatives to alleviate the symptoms of bipolar disorder.
  • ||||||||||  Biomarker, Journal:  Pharmacogenetic Testing or Therapeutic Drug Monitoring: A Quantitative Framework. (Pubmed Central) -  Jun 6, 2024   
    However, genotype prevalence and the relative influence of genotypes on the PK, as well as the ability of TDM to accurately estimate AUC with a limited number of samples, had an impact. The results could be used to support clinical decision making when considering other factors, such as the probability for severe side effects.
  • ||||||||||  risperidone / Generic mfg., olanzapine / Generic mfg., quetiapine / Generic mfg.
    Journal:  Atypical Antipsychotic Prescribing in Australian Children and Adolescents: A Survey of Medical Practitioners. (Pubmed Central) -  May 31, 2024   
    Children and adolescents were prescribed a number of atypical antipsychotics for a variety of indications, with variable perceived confidence and a relatively heavy reliance on "own or peer experience" as opposed to good quality evidence. Challenges exist for both prescribers and policymakers, and further "head-to-head" studies are needed in this age group to ensure that a balance is maintained between therapeutic benefit and safety.
  • ||||||||||  risperidone / Generic mfg.
    Journal:  Feasibility and Safety of Oral Risperidone to Treat Prehospital Agitation. (Pubmed Central) -  May 29, 2024   
    Risperidone ODT was found to be a safe and effective medication to treat mild agitation in a large urban and suburban EMS system. The need for additional medications to treat agitation was rare and there were no documented injuries to either patients or paramedics.
  • ||||||||||  lithium carbonate ER / Generic mfg.
    Journal:  Mortality risk and mood stabilizers in bipolar disorder: a propensity-score-weighted population-based cohort study in 2002-2018. (Pubmed Central) -  May 23, 2024   
    Our data showed that olanzapine and risperidone were associated with higher mortality risk than lithium, and further supported the clinical guidelines recommending lithium as the first-line mood-stabilizer for BD. Future research is required to further clarify comparative mortality risk associated with individual SGA agents to facilitate risk-benefit evaluation of alternative mood-stabilizers to minimize avoidable premature mortality in BD.
  • ||||||||||  Invega Sustenna (paliperidone palmitate extended-release 1-month injection) / J&J, Invega Trinza (paliperidone palmitate extended-release 3-month injection) / J&J
    Trial completion:  CASPAR: A Study to Assess the Treatment of Schizophrenia With Paliperidone Palmitate in Rwandan Healthcare Settings (clinicaltrials.gov) -  May 22, 2024   
    P4,  N=93, Completed, 
    Future research is required to further clarify comparative mortality risk associated with individual SGA agents to facilitate risk-benefit evaluation of alternative mood-stabilizers to minimize avoidable premature mortality in BD. Active, not recruiting --> Completed
  • ||||||||||  Journal:  Antipsychotic medications and sleep problems in patients with schizophrenia. (Pubmed Central) -  May 19, 2024   
    Prevalence of sleep problems is markedly related to the antipsychotic medication the patient uses. These findings underline the importance of considering and assessing sleep problems when treating schizophrenia patients with antipsychotics.
  • ||||||||||  Review, Journal:  Evidence for Therapeutic Drug Monitoring of Atypical Antipsychotics. (Pubmed Central) -  May 18, 2024   
    Non-response to therapeutic doses, uncertain adherence to medication, suboptimal tolerability, or pharmacokinetic drug-drug interactions are typical indications for TDM of SGAs. This review aims to summarize an overview of the current knowledge and evidence of the possibilities to tailor the dosage of selected SGAs using TDM, including the necessary pharmacokinetic parameters for personalised pharmacotherapy.
  • ||||||||||  risperidone / Generic mfg., sulpiride / Generic mfg., clozapine / Generic mfg.
    Journal:  CD73 polymorphisms are associated with schizophrenia. (Pubmed Central) -  May 17, 2024   
    Additionally, our results indicate that patients with GG genotype of rs9444348 had significantly higher likelihood of using clozapine instead of sulpiride (p?=?0.048). Overall, our data strongly suggest that genetic variations in CD73 are significantly associated with schizophrenia risk and may serve as valuable resources for identifying therapeutic targets.
  • ||||||||||  clomipramine / Generic mfg., risperidone / Generic mfg., escitalopram / Generic mfg.
    Journal:  The anti-inflammatory effects of antidepressants on colitis. (Pubmed Central) -  May 13, 2024   
    Clomipramine showed the best anti-inflammatory effect compared to Escitalopram and Risperidone. Therefore, clomipramine showed the best relieving effect on inflammation of ulcerative colitis in rats.
  • ||||||||||  Journal:  Efficacy of antipsychotics in delusional infestation. (Pubmed Central) -  May 10, 2024   
    Amisulpride and risperidone were associated with a higher treatment response than quetiapine, aripiprazole and olanzapine. Amisulpride and risperidone should therefore be considered the first-line treatment options in DI patients.
  • ||||||||||  Visken (pindolol) / Novartis
    Preclinical, Journal:  Evaluation of multitarget drugs on the expression of cocaine-induced locomotor sensitization in male rats: A comparative study. (Pubmed Central) -  May 10, 2024   
    Amisulpride and risperidone should therefore be considered the first-line treatment options in DI patients. Here we compare the efficacy of mirtazapine (MIR), pindolol (PIN), fluoxetine (FLX), risperidone (RIS), trazodone (TRZ), ziprasidone (ZPR), ondansetron (OND), yohimbine (YOH), or prazosin (PRZ), to reduce long-term cocaine-induced locomotor activity and the expression of cocaine-induced locomotor sensitization in rats...After each administration, locomotor activity for each animal was recorded for 30
  • ||||||||||  Review, Journal:  Effects of antipsychotics on the gastrointestinal microbiota: A systematic review. (Pubmed Central) -  May 5, 2024   
    Twelve articles were considered eligible for the review, which investigated the effects of risperidone (5 studies), quetiapine (3), amilsupride (1), olanzapine (1), and unspecified atypical drugs (2)...In this way, the effects of APs on GM composition and diversity were inconclusive. Despite the uncertain interactions, a more comprehensive understanding on how microbiota is affected by APs may help to optimize treatment, potentially minimizing side effects and improving adherence to treatment.
  • ||||||||||  Journal:  A case of Pitt-Hopkins syndrome: psychopharmacological approach for anxiety, insomnia, and agitation. (Pubmed Central) -  May 3, 2024   
    After admission to our hospital, aripiprazole and hydroxyzine were prescribed for anxiety and ASD-related irritability...Hydroxyzine was stopped, and quetiapine was given to eliminate sleep disturbance...For the anxiety symptoms, escitalopram was prescribed...Patients with genetic syndromes may have various psychiatric complaints. Psychopharmacological interventions should be administered carefully for the side effects.
  • ||||||||||  aripiprazole / Generic mfg., risperidone / Generic mfg., haloperidol / Generic mfg.
    Review, Journal:  The use of antipsychotics in obsessive compulsive disorder. (Pubmed Central) -  Apr 26, 2024   
    Antipsychotic augmentation may be also related to side-effects, particularly in the long term (e.g., alteration in metabolic profile, sedation, extrapyramidal symptoms). The present mini-review sought to provide the most updated evidence on augmentative antipsychotic use in treatment-resistant patients with OCD, providing a road map for clinicians in daily practice and shedding light on avenues for further research.
  • ||||||||||  risperidone / Generic mfg.
    Journal:  Relationship between plasma risperidone concentrations and clinical features in chronic schizophrenic patients in China. (Pubmed Central) -  Apr 25, 2024   
    The present mini-review sought to provide the most updated evidence on augmentative antipsychotic use in treatment-resistant patients with OCD, providing a road map for clinicians in daily practice and shedding light on avenues for further research. Long-term use of RIS should be closely monitored in older patients and females to minimize the risk of high concentrations which could induce side effects.
  • ||||||||||  hydroxyzine hydrochloride / Generic mfg., risperidone / Generic mfg.
    Journal:  Priapism Associated With the Addition of Hydroxyzine to Risperidone: A Case Report. (Pubmed Central) -  Apr 24, 2024   
    Long-term use of RIS should be closely monitored in older patients and females to minimize the risk of high concentrations which could induce side effects. This case report demonstrates the risk of addition of hydroxyzine to antipsychotics which can result in an increased risk of priapism or prolonged episodes.
  • ||||||||||  lithium carbonate ER / Generic mfg.
    Retrospective data, Journal:  Effect of antipsychotics and mood stabilisers on metabolism in (Pubmed Central) -  Apr 15, 2024   
    No abstract available After eliminating possible sensitivity, risperidone ranked 1st in elevating fasting serum glucose (SUCRA
  • ||||||||||  aripiprazole / Generic mfg., risperidone / Generic mfg.
    Cerebellar-Cortical Connectivity and Prediction of Antipsychotic Treatment Response in First-Episode Psychosis (Griffin Hall) -  Apr 14, 2024 - Abstract #SOBP2024SOBP_676;    
    In both samples, patients received baseline resting-state fMRI scans and 12-week randomized antipsychotic monotherapy with either risperidone or aripiprazole. Findings highlight the role of cerebellar cingulo-opercular, default mode, and secondary visual systems in predicting antipsychotic treatment and imply the potential of cerebellar connectivity as a prognostic biomarker in early-stage psychotic disorders.