 |
0 Diseases |  |
25 Trials |
|
25 Trials |  |
2418 News |  |
| «12...1819202122232425262728...4142» |
- | albendazole / Generic mfg.
Journal: Hapten Synthesis and Monoclonal Antibody Preparation for Simultaneous Detection of Albendazole and Its Metabolites in Animal-Origin Food. (Pubmed Central) - Dec 27, 2021
For insight into the recognition profiles of the Mab, we used computational chemistry method to parameterize cross-reactive molecules in aspects of conformation, electrostatic fields, and hydrophobicity, revealing that the hydrophobicity and conformation of characteristic group of molecules might be the key factors that together influence antibody recognition with analytes. Furthermore, the practicability of the developed ic-ELISA was verified by detecting ABZs in spiked milk, beef, and liver samples with recoveries of 60% to 108.8% and coefficient of variation (CV) of 1.0% to 15.9%.
- | albendazole / Generic mfg.
Preclinical, Journal, IO biomarker: Albendazole-loaded cubosomes interrupt the ERK1/2-HIF-1α-p300/CREB axis in mice intoxicated with diethylnitrosamine: A new paradigm in drug repurposing for the inhibition of hepatocellular carcinoma progression. (Pubmed Central) - Dec 25, 2021
These effects found to be mediated via interrupting ERK1/2-HIF-1α-p300/CREB interactions. Therefore, our findings revealed that disrupting ERK1/2-HIF-1α-p300/CREB interplay might create a novel therapeutic target for the management of HCC.
- | albendazole / Generic mfg.
Journal: Evaluation of the scolicidal activities of eugenol essential oil and its nanoemulsion against protoscoleces of hydatid cysts. (Pubmed Central) - Dec 25, 2021
This study suggested the potent scolicidal activities of Eug and Eug-NE as promising alternative scolicidal agents. Future studies are recommended to explore the mechanism of action and treatment response in vivo and clinical settings.
- | albendazole / Generic mfg.
Journal: Nanocrystal-based 3D-printed tablets: Semi-solid extrusion using Melting solidification printing process (MESO-PP) for Oral Administration of poorly soluble drugs. (Pubmed Central) - Dec 25, 2021
This method allowed the incorporation of albendazole (ABZ) nanocrystals in a concentration of up to 50% w/w, something not achieved in conventional tablets...Thus, these findings exhibit relevant pharmaceutical potential for developing stable, fast-release, oral, solid dosage forms of poorly soluble drugs combining 3D printing and nanocrystals. Additionally, this technique could be applied for printing objects using different types of nanocrystals embedded in low melting temperature polymers.
- || ivermectin oral / Generic mfg., albendazole / Generic mfg.
Clinical, Journal, Head-to-Head: Community control strategies for scabies: A cluster randomised noninferiority trial. (Pubmed Central) - Dec 23, 2021
P=N/A
One-dose was noninferior to 2-dose ivermectin-based MDA, as was a screen and treat approach, for community control of scabies. Further trials comparing these approaches in varied settings are warranted to inform global scabies control strategies.
- | moxidectin / Generic mfg., albendazole / Generic mfg.
Trial completion: Efficacy and Safety of MOX/ALB Co-administration (clinicaltrials.gov) - Dec 22, 2021
P3, N=255, Completed, Sponsor: Jennifer Keiser
Further trials comparing these approaches in varied settings are warranted to inform global scabies control strategies. Active, not recruiting --> Completed
- | ciprofloxacin oral / Generic mfg., albendazole / Generic mfg., gentamicin sulfate / Generic mfg.
Journal: Biomediated synthesis, characterization, and biological applications of nickel oxide nanoparticles derived from Toona ciliata, Ficus carica and Pinus roxburghii. (Pubmed Central) - Dec 22, 2021
The anthelmintic activity against Pheretima posthuma of nanomaterials obtained from Pinus roxburghii was found to be greater than that derived from Toona ciliata and Ficus carica using the standard drug Albendazole. This method takes the advantage of the sustainable and economic approach for the synthesis of metal oxide nanoparticles.
- | Preclinical, Journal: In vitro and in vivo efficacy of thiacloprid against Echinococcus multilocularis. (Pubmed Central) - Dec 21, 2021
This method takes the advantage of the sustainable and economic approach for the synthesis of metal oxide nanoparticles. The results demonstrated that thiacloprid had parasiticidal activity against E. multilocularis in vitro and in vivo, and could be used as a novel lead compound for the treatment of AE.
- | albendazole / Generic mfg.
Journal: Anthelmintic activity of methanol extract of Dennettia tripetala G. Baker (Annonaceae) fruits against Haemonchus contortus in red Sokoto goats. (Pubmed Central) - Dec 21, 2021
Groups 4 and 5 were treated with albendazole (7.5 mg/kg) once and distilled water (5 ml) respectively and served as treated and untreated controls...The total plasma protein (TPP) and FAMACHA scoring values were significantly improved (P < 0.05) in the treated groups. These results indicate that methanol extract and fractions of D. tripetala fruits possess beneficial anthelmintic activity against H. contortus and may be a suitable alternative anthelmintic candidate for the control of haemonchosis in goats.
- || albendazole / Generic mfg.
Review, Journal: Literature Review of Gongylonema pulchrum: A Rare Nematode. (Pubmed Central) - Dec 21, 2021
A better understanding of the etiopathogenesis of Gongylonema infections will facilitate the diagnosis and treatment of this infection. Keywords: Gongylonema pulchrum, caprophage insects, psychosis, albendazole.
- | albendazole / Generic mfg., levamisole / Generic mfg.
Preclinical, Journal: First Report of Multiple Drug-resistant Gastrointestinal Nematodes of Sheep in Arbat District, Sulaymaniyah, Iraq Detected By in Vivo and in Vitro Methods. (Pubmed Central) - Dec 20, 2021
The mean IC of albendazole, ivermectin, and levamisole were 0.073 ng/mL, 7.97 ng/mL, and 1.43 ng/mL, respectively. This study is the first Iraqi report of AR confirmed by both in vivo FECRT and in vitro LDA methods.
- | mebendazole / Generic mfg., albendazole / Generic mfg.
Journal: Molecular modelling and de novo fragment-based design of potential inhibitors of beta-tubulin gene of Necator americanus from natural products. (Pubmed Central) - Dec 17, 2021
The identified compounds can serve as treasure troves from which future potent anthelmintics can be designed. The current study strives to assuage the hookworm disease burden, especially making available molecules with the potential to circumvent the chemoresistance.
- | albendazole / Generic mfg.
Journal: Chronic administration of cryptolepine nanoparticle formulation alleviates seizures in a neurocysticercosis model. (Pubmed Central) - Dec 16, 2021
Treatment with SLN-CRYP significantly shrunk cysticerci and resolved ventricular expansion and deviation similar to albendazole on examination of encephala...SLN-CRYP significantly reduced brain homogenate levels of IL-10 (p = 0.0016) and IFN-γ (p < 0.0001). Our study shows that the chronic administration of the nanoparticle formulation of cryptolepine is effective in alleviating seizures associated with neurocysticercosis in a mouse model.
- | moxidectin / Generic mfg., albendazole / Generic mfg.
Journal: Effects of long-acting, broad spectra anthelmintic treatments on the rumen microbial community compositions of grazing sheep. (Pubmed Central) - Dec 16, 2021
In contrast, the LAI treatment increased the relative abundances of members of the Veillonellaceae and resulted in minor changes to the bacterial and fungal communities by day 77. Overall, the anthelmintic treatments resulted in few, but highly significant, changes to the rumen microbiota composition.
- | albendazole / Generic mfg., lansoprazole / Generic mfg.
Preclinical, Journal: Potential Antidiabetic Activity of Benzimidazole Derivative Albendazole and Lansoprazole Drugs in Different Doses in Experimental Type 2 Diabetic Rats. (Pubmed Central) - Dec 16, 2021
The lansoprazole and albendazole treatments can be a potential drug or combined with antidiabetic drugs in T2D treatment by AMPK, PPAR, incretin-like effect and other antidiabetic mechanisms. It may be beneficial to create an effective treatment strategy by developing more specific substances with benzimidazole scaffold.
- | albendazole / Generic mfg., nitazoxanide / Generic mfg.
Journal: MDR1 protein (ABC-C1) Over Expression in Giardia Intestinalis Incubated with Albendazole and Nitazoxanide. (Pubmed Central) - Dec 16, 2021
It may be beneficial to create an effective treatment strategy by developing more specific substances with benzimidazole scaffold. These findings in Giardia intestinalis, support the possible role of ABC-C1 in drug efflux.
- || niclosamide / Generic mfg.
Review, Journal: Progress in Redirecting Antiparasitic Drugs for Cancer Treatment. (Pubmed Central) - Dec 16, 2021
Moreover, we also paid attention to what limits the clinical application of these agents. For some of these agents like ARTs and niclosamide, drug modification, novel delivery system invention, or drug combination are strongly recommended for future exploration.
- | albendazole / Generic mfg.
Journal: Albendazole induces the terminal differentiation of acute myeloid leukaemia cells to monocytes by stimulating the Krüppel-like factor 4-dihydropyrimidinase-like 2A (KLF4-DPYSL2A) axis. (Pubmed Central) - Dec 16, 2021
With the goal to identify novel compounds that can effectively and safely induce the terminal differentiation of non-acute promyelocytic leukaemia (APL) AML cells, we performed a chemical screening and identified albendazole (ABZ), a widely used anti-helminthic drug, as a promising lead compound that can differentiate non-APL AML cells by stimulating the Krüppel-like factor 4-dihydropyrimidinase-like 2A (KLF4-DPYSL2A) differentiation axis to the monocytes. Our in vitro and in vivo findings demonstrate that ABZ is an attractive candidate drug as a novel differentiation chemotherapy for patients with non-APL AML.
- || albendazole / Generic mfg., praziquantel / Generic mfg.
Clinical, Journal: Evaluation of mass drug administration for schistosomiasis and soil-transmitted helminths in school-aged children in Bankass, Mali. (Pubmed Central) - Dec 16, 2021
The data showed satisfactory coverage >90%, in contrast with lower rates initially reported by the district health information system. These results raise concerns about the reliability of programmatic data and highlight the importance of population-based surveys for the evaluation of control interventions.
- || ivermectin oral / Generic mfg.
Clinical, Journal: Gastrointestinal parasitic infections of buffaloes (Bubalus bubalis) in Sarawak Borneo: Prevalence, risk factors, and farming practices. (Pubmed Central) - Dec 16, 2021
Most farmers practised deworming, and ivermectin was the most commonly used anthelminthic (60.4%); only 1.9% of farmers used albendazole...Although farmers report they are aware of parasitic diseases, further education is still required. This could include how they can successfully implement on-farm changes to reduce the prevalence of GI parasites in their herds.
- | albendazole / Generic mfg.
Journal: Assessing factors influencing communities' acceptability of mass drug administration for the elimination of lymphatic filariasis in Guyana. (Pubmed Central) - Dec 16, 2021
Results from this study set a baseline level for key indicators and acceptability, from which the acceptability of IDA can be measured. Regional variations across indicators suggest that localized approaches should be considered for social mobilization and MDA delivery to capture these contextual differences.
- | albendazole / Generic mfg.
Journal: Toxocariasis affecting brain stem and skull base. (Pubmed Central) - Dec 14, 2021
With the appropriate personal history, toxocariasis should be included in the differential diagnosis of infiltrating lesions of the skull base with a negative study of tumor histology. Albendazole treatment has been shown to control and cure the disease.
- || albendazole / Generic mfg.
Clinical, Journal: Myositis Caused by Trachipleistophora hominis in a Person With Human Immunodeficiency Virus: The First Case in Thailand. (Pubmed Central) - Dec 10, 2021
He gradually improved, and was discharged home 6 weeks after hospitalization. To the best of our knowledge, this is the first report of microsporidial myositis caused by Trachipleistophora hominis in a person with HIV in Thailand.
- | mebendazole / Generic mfg., albendazole / Generic mfg.
Trial completion date, Trial primary completion date: StarwormsWP2: Monitoring Drug Efficacy and Anthelmintic Resistance in Soil-transmitted Helminth Programs (clinicaltrials.gov) - Dec 8, 2021
P=N/A, N=8000, Recruiting, Sponsor: University Ghent
To the best of our knowledge, this is the first report of microsporidial myositis caused by Trachipleistophora hominis in a person with HIV in Thailand. Trial completion date: Feb 2021 --> Dec 2022 | Trial primary completion date: Jan 2021 --> Dec 2022
- || albendazole / Generic mfg., praziquantel / Generic mfg.
Review, Journal: DRUG ASSOCIATIONS AS ALTERNATIVE AND COMPLEMENTARY THERAPY FOR NEGLECTED TROPICAL DISEASES. (Pubmed Central) - Dec 1, 2021
It was also possible to verify that the FDCs promote a simplification of the therapeutic regimen, which promotes better patient compliance and enables a reduction in the development of parasitic resistance, requiring further studies aimed at resistant strains, since the combined APIs usually act by different mechanisms or at different target sites. In addition to eliminating the process of developing a new drug based on the identification and validation of active compounds, which is a complex, long process and requires a strong long-term investment, other advantages that FDCs have are related to productive gain and gain from the industrial plant, which can favor and encourage the R&D of new FDCs not only for NTDs but also for other diseases that require the use of more than one drug.
- || albendazole / Generic mfg.
Clinical, Journal, Monotherapy: The combination of carvacrol and albendazole enhanced the efficacy of monotherapy in experimental alveolar echinococcosis. (Pubmed Central) - Dec 1, 2021
In conclusion, carvacrol and albendazole combination enhanced the efficacy of monotherapy. This strategy would allow to improve the efficacy of the treatment without increasing the doses of albendazole or lengthen the treatment period, reducing the occurrence of adverse effects.
- || albendazole / Generic mfg., praziquantel / Generic mfg., cimetidine / Generic mfg.
Clinical, Journal: Orbital cysticercosis: clinical features and management outcomes. (Pubmed Central) - Nov 29, 2021
A high index of suspicion and a thorough knowledge of the clinical and radiological features are necessary for the proper diagnosis and management of orbital cysticercosis. Medical management with oral albendazole combined with oral steroids leads to desired outcome in the majority.
- || albendazole / Generic mfg.
Preclinical, Review, Journal: Human filariasis-contributions of the Litomosoides sigmodontis and Acanthocheilonema viteae animal model. (Pubmed Central) - Nov 29, 2021
Thus, efforts to control and eliminate filarial diseases were already launched by the WHO in the 1970s, especially against lymphatic filariasis and onchocerciasis, and are mainly based on mass drug administration (MDA) of microfilaricidal drugs (ivermectin, diethylcarbamazine, albendazole) to filarial endemic areas accompanied with vector control strategies with the goal to reduce the transmission...Mouse models provide an important platform for anti-filarial drug research in a preclinical setting. This review presents an overview about the Litomosoides sigmodontis and Acanthocheilonema viteae filarial mouse models and their role in immunological research as well as preclinical studies about novel anti-filarial drugs and treatment strategies.
- | albendazole / Generic mfg.
Preclinical, Journal: Innate and adaptive immune responses following PD-L1 blockade in treating chronic murine alveolar echinococcosis. (Pubmed Central) - Nov 29, 2021
Findings showed that the parasite load was significantly reduced in response to PD-L1 blockade, and this blockade a) contributed to T cell activity by increasing CD4 /CD8 effector T cells, and decreasing Tregs; b) had the capacity to re-store DCs and Kupffer cells/Macrophages; c) suppressed NKT and NK cells; and thus d) lead to an improved control of E. multilocularis infection in mice. This study suggests that the PD-L1 pathway plays an important role by regulating adaptive and innate immune cells against E. multilocularis infection, with significant modulation of tissue inflammation.
- | albendazole / Generic mfg., atovaquone / Generic mfg.
Preclinical, Journal, Combination therapy: In vivo efficacy of combination therapy with albendazole and atovaquone against primary hydatid cysts in mice. (Pubmed Central) - Nov 29, 2021
Furthermore, compared with ABZ alone, the combination treatment significantly reduced the growth of the primary cyst in the liver of mice infected orally with parasite eggs (P = .011). ATV enhances the effect of ABZ in the treatment of AE in mice.
- | albendazole / Generic mfg.
Preclinical, Journal: In vivo exposure of Albendazole sulphoxide by Haemonchus contortus and correlation between plasma and target tissue or gastrointestinal content dispositions in goats. (Pubmed Central) - Nov 29, 2021
The parent drug and its metabolite were recovered in both male and female H. contortus. This study indicates that in goats the plasma concentration profiles of RBZ are strongly correlated with those achieved in different target tissues or fluids, which in turn, reflect the amount of drug taken up by parasites.
- | albendazole / Generic mfg.
Journal: Hepatic Alveolar Echinococcosis. (Pubmed Central) - Nov 29, 2021
Surgical resection, if feasible, is the gold standard for treatment, and more patients are currently eligible for this option because of an earlier diagnosis. The prognosis has considerably improved but remains poor in countries where access to care is less favorable.
- | albendazole / Generic mfg.
Journal: Investigation of anthelmintic activity of the acetone extract and constituents of Typha capensis against animal parasitic Haemonchus contortus and free-living Caenorhabditis elegans. (Pubmed Central) - Nov 29, 2021
Typha capensis acetone extract had the strongest egg hatching inhibitory effect with an EC of 184.94 μg/mL, and this extract also halted larval development of H. contortus with an EC of 83.30 μg/mL compared to the positive control (albendazole) with an EC of 2.66 μg/mL...Identification of bioactive compounds from the T. capensis crude extract supports development of this extract as a complementary or alternative treatment against haemonchosis. However, further research is necessary to confirm the anthelmintic efficacy of the plant, including in vivo studies.
- || albendazole / Generic mfg.
Clinical, Journal: Clinical tolerance and efficacy of anti-parasitic treatment with albendazole in patients with alveolar echinococcosis: long-term follow-up observation in 117 patients. (Pubmed Central) - Nov 29, 2021
The effectiveness of the anti-parasitic treatment was manifested in the inhibition of tumor development in 88% of patients in group R and 60% in group N. Follow-up of group R patients from 3 to 14 years did not reveal new lesions of the liver and other organs. The chance of a complete cure depends on the early detection of a parasitic tumor and can reach 50%.
- | albendazole / Generic mfg.
Preclinical, Journal: Anthelmintic activity of pomegranate peel extract (Punica granatum) and synthetic anthelmintics against gastrointestinal nematodes in cattle, sheep, goats, and buffalos: in vivo study. (Pubmed Central) - Nov 29, 2021
The animals under experiment were divided into four groups: the first group (negative control) was not given any drugs, the second group was given ivermectin (0.5 ml/25 kg bwt) (positive control 1), the third group was given albendazole (2.5 mg active principle/kg bwt) (positive control 2), and the fourth group was given PPE (200 mg/kg bwt)...While in the fourth group, there was a decrease in FEC by 97%. In conclusion, PPE could be used as a safe, cheap, and effective natural anthelmintic against PGE.
- | albendazole / Generic mfg.
Journal: Cysticidal effect of a pure naphthoquinone on Taenia crassiceps cysticerci. (Pubmed Central) - Nov 29, 2021
The drug of choice to treat this disease is albendazole; however, the bioavailability and efficacy of the drug are variable...In conclusion, naphthoquinone 4a has in vitro cysticidal activity on T. crassiceps cysticerci depending on the duration of the treatment and the concentration of the compound. Therefore, it is a promising drug candidate to be used in T. crassiceps and possibly T. solium infections.
- | albendazole / Generic mfg.
Preclinical, Journal: In vitro evaluation of albendazole-loaded nanostructured lipid carriers on Echinococcus granulosus microcysts and their prophylactic efficacy on experimental secondary hydatidosis. (Pubmed Central) - Nov 29, 2021
The cysts treated with ABZ-NLCs showed marked ultrastructural changes in the germinal layer. This study demonstrated that both in vitro and in vivo treatments with ABZ-NLCs are significantly more efficient than treatment with free ABZ against E. granulosus protoscoleces, metacestodes, and prevention of cyst development in mice.
- | albendazole / Generic mfg.
Preclinical, Journal: Assessing the Efficacy of Albendazole against Fasciola hepatica in Naturally Infected Cattle by In Vivo and In Vitro Methods. (Pubmed Central) - Nov 29, 2021
Ovicidal activity at a concentration of 0.5 μM in the 12-h version suggested a reduced efficacy of ABZ (65.40%). An EHT prepared using pooled faecal samples was a prospective method for the detection of efficacy and ABZ resistance in F. hepatica.
- | albendazole / Generic mfg.
Preclinical, Journal: Elimination of Giardia duodenalis BIV in vivo using natural extracts in microbiome and dietary supplements. (Pubmed Central) - Nov 25, 2021
These natural compounds were administered in a dose of 100 mg/day and were compared to G. duodenalis-infected mice treated with albendazole (ALB; 50 mg/Kg/day) and metronidazole (MET; 500 mg/Kg/day), the conventional therapies used to this day...MBX and BIO alone or associated eliminated G. duodenalis without apparent adverse effects and animals of these groups showed better clinical performance in relation to those with high parasitic load. MET, ALB and CPR only decreased the number of cysts, indicating limitations and therapeutic failure.
- || albendazole / Generic mfg.
Clinical, Journal: Echinococcosis in both heart and lungs, the first case reported in Albania. (Pubmed Central) - Nov 24, 2021
The therapy was continued until the lung intervention and for 12 weeks post-operatively. The patient had an uneventful recovery and after about 4 years.
- | albendazole / Generic mfg.
Retrospective data, Journal: Long-term follow-up of liver alveolar echinococcosis using echinococcosis multilocularis ultrasound classification. (Pubmed Central) - Nov 21, 2021
The sonomorphology of hepatic AE lesions may change over time. The hemangioma-like and pseudocystic patterns are affected.
- | ivermectin oral / Generic mfg., albendazole / Generic mfg., tetracycline / Generic mfg.
Journal: Veterinary Drug Prescribing Practices at Selected District Veterinary Clinics of Rift Valley Areas of Ethiopia. (Pubmed Central) - Nov 21, 2021
Among the total drugs, oxytetracycline, ivermectin, penstrep, sulfa drugs, and albendazole were the most leading prescribed drugs with a frequency of 43.0%, 17.6%, 10.2%, 6.5%, and 1.3%, respectively...In conclusion, this study revealed problems in antibiotics and anthelmintics use, description of routes of administration and length of treatment, and shortage of laboratory diagnostic facilities. Therefore, veterinary drugs, particularly antibiotics and anthelmintics, should be used appropriately to safeguard the public from residual drug impacts and resistance development.
- || albendazole / Generic mfg.
Clinical, Journal: The Proportion of Infectious Disease Cases, Its Associated Factors, and the Appropriateness of Antimicrobial Prescription Among Rohingya Refugee Pediatric Patients in IMARET Mobile Clinics. (Pubmed Central) - Nov 21, 2021
Only 7.4% were appropriately prescribed antimicrobials. Age (p = 0.005) and BMI (p = 0.006) were significantly associated with infections.
- || albendazole / Generic mfg.
Clinical, Journal: A strong effect of individual compliance with mass drug administration for lymphatic filariasis on sustained clearance of soil-transmitted helminth infections. (Pubmed Central) - Nov 21, 2021
Age (p = 0.005) and BMI (p = 0.006) were significantly associated with infections. Our results illustrate the importance of MDA compliance at the level of the individual with respect to the STH benefit provided by semiannual ALB MDA, which is used for the elimination of LF in Central Africa.
- | albendazole / Generic mfg.
Journal: Lymphatic filariasis elimination in the Dominican Republic: History, progress, and remaining steps. (Pubmed Central) - Nov 21, 2021
Beginning in 2002, PELF sequentially implemented mass drug administration (MDA) in these foci using albendazole and diethylcarbamazine (DEC)...This success has been achieved against a shifting landscape of limited domestic funding, competing domestic public health priorities, and sporadic external donor support. Remaining steps include the need to scale-up morbidity management and disability prevention services for LF and to continue PTS until LF transmission is interrupted across Hispaniola.
- | albendazole / Generic mfg.
Journal: Factors associated with soil-transmitted helminths infection in Benin: Findings from the DeWorm3 study. (Pubmed Central) - Nov 21, 2021
P3
are the most prevalent STH in Comé, with a persistent reservoir in adults that is not addressed by current control measures based on school MDA. Expanding MDA to target adults and PSAC is necessary to substantially impact population prevalence, particularly for hookworm.
- | albendazole / Generic mfg.
Journal: Accuracy of an experimental whole-blood test for detecting reactivation of echinococcal cysts. (Pubmed Central) - Nov 21, 2021
On the contrary, the levels of IL-1ra, IL-6, IL-8, G-CSF, IFN-γ, IP-10, MCP-1, MIP-1α, FGF significantly decreased in active CE during follow-up. Additional studies are needed to understand whether these findings might have a clinical significance for patients' follow-up.
- | Xifaxan (rifaximin) / Alfa Wassermann, Bausch Health, Norgine, ASKA Pharma
Journal: Explicating the molecular level drug-polymer interactions at the interface of supersaturated solution of the model drug: Albendazole. (Pubmed Central) - Nov 21, 2021
Further, modification in the solid state of ABZ revealed influence of polymers on its precipitation behaviour. We conclude that PVA and PVP K30 act as nucleation and crystal growth inhibitor, respectively in the precipitation inhibition of ABZ.
- | albendazole / Generic mfg.
New P2/3 trial, Head-to-Head: ALIVE: Evaluation of Effectiveness of ALBENDAZOLIVERMECTIN Coformulation vs ALBENDAZOLE for Treatment of Intestinal Worms (clinicaltrials.gov) - Nov 18, 2021
P2/3, N=1223, Not yet recruiting, Sponsor: Barcelona Institute for Global Health
- | albendazole / Generic mfg.
Journal, IO biomarker: My experience on taeniasis and neurocysticercosis. (Pubmed Central) - Nov 17, 2021
The above studies suggest that taeniasis and NCC are alarmingly high in the pig farming community of North India. Taeniasis in human and cysticercosis in swine due to T. asiatica call for further studies on this parasite.