prednisolone / Generic mfg. 
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 153 Diseases   74 Trials   74 Trials   10107 News 


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  • ||||||||||  Cytovene (ganciclovir) / Roche
    Clinical, Retrospective data, Journal:  The Effect of Topical Ganciclovir and Corticosteroid on Cytomegalovirus Corneal Endotheliitis in Korean Patients. (Pubmed Central) -  Jan 9, 2020   
    The developed SMEDDS are a feasible option to conventional eye drops for its capability to improve bioavailability via its longer precorneal residence time and its capacity to sustain the release of the drug. Long-term maintenance therapy with topical GCV and corticosteroids are effective and maintain corneal endothelial function in Korean patients with CMV endotheliitis.
  • ||||||||||  prednisolone / Generic mfg., methotrexate / Generic mfg., mycophenolate mofetil / Generic mfg.
    Clinical, Review, Journal:  Challenges in the diagnosis and treatment of disabling pansclerotic morphea of childhood: case-based review. (Pubmed Central) -  Jan 8, 2020   
    There was subjective improvement with prednisolone and mycophenolate mofetil (MMF)...Methotrexate and corticosteroids have been the most commonly utilized...Eventually, most children require multi-modal and high-dose immunosuppressive therapies to reduce the inflammation inflicted by the disease. Long-term antibiotics and nutritional support are important in the ongoing care of these patients.
  • ||||||||||  prednisolone / Generic mfg.
    Clinical, Journal:  A Case of Perineuritis Successfully Treated with Early Aggressive Immunotherapy. (Pubmed Central) -  Jan 8, 2020   
    A sural nerve biopsy revealed perineuritis, consisting of inflammatory cell infiltration and swelling of the perineurium. Oral prednisolone, plasma exchange and intravenous immunoglobulin treatment were all effective, leading to significant improvement of the symptoms.
  • ||||||||||  prednisolone / Generic mfg., prednisone / Generic mfg., Keytruda (pembrolizumab) / Merck (MSD)
    Clinical, Journal, Checkpoint inhibition:  Tenosynovitis Induced by an Immune Checkpoint Inhibitor: A Case Report and Literature Review. (Pubmed Central) -  Jan 8, 2020   
    Prednisolone immediately relieved the symptoms, and the tumor was still shrinking on day 21 after eight cycles of pembrolizumab. ICI-induced tenosynovitis was managed while continuing ICI usage, suggesting that 0.5 mg/kg/day prednisone might be effective for tenosynovitis without ICI cessation.
  • ||||||||||  prednisolone / Generic mfg.
    Trial initiation date:  Intraorbital Injection Versus Oral Steroid in Anterior Idiopathic Orbital Inflammation (clinicaltrials.gov) -  Jan 7, 2020   
    P3,  N=120, Not yet recruiting, 
    ICI-induced tenosynovitis was managed while continuing ICI usage, suggesting that 0.5 mg/kg/day prednisone might be effective for tenosynovitis without ICI cessation. Initiation date: Nov 2019 --> Mar 2020
  • ||||||||||  tacrolimus / Generic mfg., Humira (adalimumab) / Eisai, AbbVie
    Journal:  Vogt-Koyanagi-Harada disease. (Pubmed Central) -  Jan 5, 2020   
    Clinicians should consider Vogt-Koyanagi-Harada disease in patients presenting with headache with acute profound visual loss. A prompt diagnosis and immunosuppressive therapy can lead to complete resolution.
  • ||||||||||  methylprednisolone oral / Generic mfg.
    managing PUK with cataract () -  Jan 5, 2020 - Abstract #AIOC2020AIOC_2268;    
    first stage banana graft followed by phacoemulsification with foldable IOLgiving good visual recovery. prior to banana graft medical management by iv methyl prednisolone pulse doses and immunosuppressive therapy was givwn
  • ||||||||||  Avelox (moxifloxacin) / Bayer
    All that glitters is not gold ! () -  Jan 5, 2020 - Abstract #AIOC2020AIOC_907;    
    prior to banana graft medical management by iv methyl prednisolone pulse doses and immunosuppressive therapy was givwn Timing of IOFB removal is decided according to FB characteristic and associated trauma.Patient gained good visual outcome.Co-existent PC tears need to be anticipated and dealt with when found.
  • ||||||||||  prednisolone / Generic mfg.
    Out of the blues: "Bilateral serous macular detachment" () -  Jan 5, 2020 - Abstract #AIOC2020AIOC_893;    
    Bilateral serous macular detachment is a rare entity and needs early treatment. Meticulous evaluation of the differentials, close monitoring are needed for successful treatment outcome.
  • ||||||||||  methylprednisolone oral / Generic mfg.
    Bilateral optic atrophy due to Neuromyelitis Optica Spectrum Disorder(NMOSD) () -  Jan 5, 2020 - Abstract #AIOC2020AIOC_833;    
    Case Report A 30 yr old female presented with painful diminution of vision in LE.O/E:BCVA in RE- PL+ & LE-6/18,RE-non reactive pupil & LE was ill sustained,color vision was non recordable in RE & impaired in LE.On fundoscopy RE- total optic atrophy(OA) & LE temporal disc pallor.Patient gave H/O recurrent episodes in BE since 6 yrs,she was diagnosed to have NMOSD based on MRI findings & positive Anti NMO antibody.Diagnosis of RE OA & LE partial OA with acute retrobulbar neuritis was made.She was started on IV Methylprednisolone 1g,5 doses & tapering doses of oral prednisolone.She was referred to neurophysician. Conclusion B/L recurrent retrobulbar neuritis leading to optic atrophy is a common manifestation of NMOSD.
  • ||||||||||  prednisolone / Generic mfg., azathioprine orodispersible / Generic mfg.
    A rare case report of orbital pseudotumour in SLE () -  Jan 5, 2020 - Abstract #AIOC2020AIOC_799;    
    Orbital pseudotumours are disorders characterized by orbital inflammation without any identifiable local or systemic cause. A 40 year old female came with proptosis of the R/E since 5 days ,with marked conjunctival chemosis and hyperemia,with restricted EOM,gradual diminution of vision and watering since 5 days.Swelling gradually regressed,but involved L/E within 5 days,with marked swelling of the eyelids,painful,with restricted EOM.V/A was PL+ in R/E and HM+ in the L/E.There was corneal dystrophy in B/E.CT SCAN ORBITS-diffuse eccentric thickenings of right orbital globe,marked scleral affection with periscleral thickening,suggestive of scleritis of orbital pseudotumour.ANA IFA:+(1:80 dilution),ANA BLOT-antidsDNA+/-,antissA/R060+,antiRibP0+/-,ANA hep 2+,ESR-105 mm/hr TREATMENT:The case responded to oral prednisolone in the dose of 1mg/kg bw tapered over 3 months along with oral azathioprine 50 mg once daily for 30 days .The patient has no episode of recurrence till now.
  • ||||||||||  Decadron (dexamethasone) / Merck (MSD), methylprednisolone oral / Generic mfg.
    OCULAR MASQUERADE SYNDROME - A RARE CASE REPORT () -  Jan 5, 2020 - Abstract #AIOC2020AIOC_518;    
    MRI repeated in view of masquerade syndrome showed altered intensity lesion involving right orbital apex likely metastatic deposits.Patient diagnosed with testicular synovial sarcoma and referred to radiotherapy department for further management. Along with radiotherapy dexamethasone started for ocular involvement.
  • ||||||||||  prednisolone / Generic mfg.
    Journal:  Propylthiouracil-induced anti-neutrophil cytoplasmic antibody-associated vasculitis mimicking Kawasaki disease. (Pubmed Central) -  Jan 4, 2020   
    She met the diagnostic criteria for KD and received intravenous immunoglobulin (IVIG) combined with prednisolone, with rapid resolution of clinical and laboratory parameters...A high titre of myeloperoxidase ANCA was detected in the patient's serum on admission, and the titre decreased during the convalescent stage. This case demonstrates that children with PTU-associated AAV may present with clinical features mimicking KD, and that IVIG along with corticosteroid therapy may be effective in treating patients with drug-induced severe systemic AAV.
  • ||||||||||  cyclophosphamide intravenous / Generic mfg.
    Retrospective data, Journal:  A retrospective study of the CHOP, CHOPE, and CHOPE/G regimens as the first-line treatment of peripheral T-cell lymphomas. (Pubmed Central) -  Jan 2, 2020   
    More difluprednate-treated eyes were quiet following 21 days of treatment, and difluprednate-treated patients were much less likely to be withdrawn from the study because of treatment failure. Compared with CHOP alone, CHOPE regimen improved the efficacy and survival; while the addition of gemcitabine in the front-line therapy resulted in more adverse events without benefit of survival.
  • ||||||||||  doxorubicin hydrochloride / Generic mfg., cyclophosphamide intravenous / Generic mfg., Rituxan (rituximab) / Roche, Biogen
    Clinical, Journal:  Association between Comorbidity and Relative Dose Intensity in Patients with Diffuse Large B-Cell Lymphoma. (Pubmed Central) -  Jan 2, 2020   
    Our results demonstrated that the presence of comorbidity was associated with insufficient RDI and poor treatment outcome in DLBCL patients treated with R-CHOP. To optimize the RDI maintenance to achieve better outcomes for DLBCL patients, further investigation of comorbidities is required.
  • ||||||||||  cyclophosphamide intravenous / Generic mfg.
    Clinical, Journal:  Two Cases of Pneumocystis Pneumonia during Adjuvant Chemotherapy for Breast Cancer (Pubmed Central) -  Jan 2, 2020   
    Case 2: After receiving 4 cycles of postoperative ddEC, a 27-year-old woman developed PCP after 1 cycle of docetaxel(DTX)administration...The onset of PCP is presumed to be related to the steroid dose administered and the number of lymphocytes. Therefore, determining effective indicators in patients at a high risk of PCP onset is important.
  • ||||||||||  prednisolone / Generic mfg.
    Journal:  Prednisolone Does Not Regulate Factor VIII Expression in Mice Receiving AAV5-hFVIII-SQ: Valoctocogene Roxaparvovec. (Pubmed Central) -  Jan 1, 2020   
    Liver hFVIII-SQ DNA, RNA, and plasma hFVIII-SQ protein and activity increased in a dose-dependent manner, with or without prednisolone. In summary, chronic prednisolone treatment in mice treated with AAV5-hFVIII-SQ did not modulate levels of liver hFVIII-SQ DNA, RNA, or the percentage and distribution of hFVIII-SQ-positive hepatocytes, nor did it regulate levels of plasma hFVIII-SQ protein or activity, or affect levels of plasma AST or ALT.
  • ||||||||||  prednisolone / Generic mfg., methotrexate / Generic mfg., Azulfidine (sulfasalazine) / Generic mfg.
    Journal:  Normal mortality of the COBRA early rheumatoid arthritis trial cohort after 23 years of follow-up. (Pubmed Central) -  Jan 1, 2020   
    This prospective trial cohort study of early RA is one of the first to show similar mortality compared with the general population after 23 years of follow-up. It confirms that early, intensive treatment of RA has long-term benefits and suggests that treating to target is especially important for patients with poor prognosis.
  • ||||||||||  prednisolone / Generic mfg.
    Clinical, Journal:  Prognostic Value of Neutrophil-lymphocyte Ratio in Patients with Severe Alcoholic Hepatitis. (Pubmed Central) -  Dec 31, 2019   
    Background Prednisolone is considered the cornerstone treatment for severe alcoholic hepatitis (AH)...Combining these two models to create a "modified" Lille score adds increased performance characteristics to the prediction of outcomes/mortality. The "modified" Lille score presented in this study can be used to further cut down the number of non-responders who are often forced to undergo costly and potentially harmful treatment courses.
  • ||||||||||  tacrolimus topical / Generic mfg.
    Clinical, Review, Journal:  Topical Tacrolimus as an adjunct to Conventional Therapy for Stromal Herpetic Keratitis: a Randomized Clinical Trial. (Pubmed Central) -  Dec 26, 2019   
    The case group had a lower mean logarithm of the minimum angle of resolution (LogMAR) for BCVA, lower grading scores, and steeper decreasing trends for corneal haziness, edema, neovascularization, and epitheliopathy compared to the control group after the second week (P 0.05), while IOP remained unchanged between groups (P 0.05). The addition of 0.05% topical tacrolimus enhances visual acuity and reduces corneal inflammation, neovascularization, and scarring; thus, it can used as an appropriate adjunct treatment for patients with HSK.
  • ||||||||||  prednisolone / Generic mfg.
    Journal:  Gangrenous ischaemic colitis following lung wedge resection. (Pubmed Central) -  Dec 26, 2019   
    A 77-year-old man, who was taking prednisolone 7.5 mg, underwent wedge resection for nodules in the right lower lobe of the lung...Although gangrenous ischaemic colitis is not a complication specific to general thoracic surgery, it can be fatal. Because of the high risk of developing gangrenous ischaemic colitis in elderly patients and the increase in concomitant diseases, thoracic surgeons should always be mindful of the condition.
  • ||||||||||  prednisolone / Generic mfg.
    Journal:  Heroin Use Is Associated with AA-Type Kidney Amyloidosis in the Pacific Northwest. (Pubmed Central) -  Dec 24, 2019   
    Injection heroin use is strongly associated with kidney AA amyloidosis in the Pacific Northwest. Unique aspects of heroin use, in particular geographic regions or frequent associated soft-tissue infections, may be an important cause of this progressive kidney disease.