prednisolone / Generic mfg. 
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 153 Diseases   74 Trials   74 Trials   10107 News 


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  • ||||||||||  tacrolimus / Generic mfg.
    Tacrolimus, a boon for elderly-onset ulcerative colitis! () -  Dec 12, 2020 - Abstract #IDDF2020IDDF_197;    
    Conclusions Tacrolimus provides some signs of effectiveness for treating elderly-onset UC. However, more thorough research is needed to assess the effectiveness and safety of this therapy in this vulnerable population.
  • ||||||||||  [VIRTUAL] A RARE CASE OF SELLAR PATHOLOGY: COINCIDING IGG4-RELATED HYPOPHYSITIS AND PITUITARY ADENOMA () -  Dec 2, 2020 - Abstract #ENEA2020ENEA_63;    
    Prednisolone was initiated (four-week course; 30 mg with gradual tapering to 5 mg daily) leading to full recovery of his right visual field and acuity, shrinkage of the sellar and pancre- atic lesions and lymph nodes, and decrease in serum IgG and IgG4 levels...Although hypophysitis is the most common manifestation of IgG4-related disease in the sellar region, in our patient, dural involvement was also present. This case also high-lights the importance of broad differential diagnosis when ap- proaching pituitary abnormalities on imaging.
  • ||||||||||  doxorubicin hydrochloride / Generic mfg., cyclophosphamide intravenous / Generic mfg.
    [VIRTUAL] Uncovering a Mimic: Laboratory Testing in Adult T Cell Leukemia/Lymphoma () -  Dec 2, 2020 - Abstract #ASDP2020ASDP_446;    
    It appears that ATLL tumor cell phenotypes slightly change as disease progresses. Broad differentiation diagnosis and comprehensive assessment are crucial for patient management.
  • ||||||||||  tacrolimus / Generic mfg.
    [VIRTUAL] An Unusual Case of Granulomatous Inflammation () -  Dec 2, 2020 - Abstract #ASDP2020ASDP_269;    
    His medical history was significant for a renal transplantation 2 years prior due to type 2 diabetes, necessitating immunosuppression with oral azathioprine, tacrolimus and prednisolone...The patient was treated with 200mg/day of oral voriconazole for 6-months with significant clinical improvement of all lesions...This pathogen typically causes soft tissue infections in immunosuppressed hosts as noted in all twelve reported cases, including ours. This case highlights the need to recognise emergent and unusual pathogenic fungi in immunosuppressed patients and supports the role of DNA sequencing for accurate fungal identification.
  • ||||||||||  prednisolone / Generic mfg.
    Clinical, Journal:  Case Report: Acute Vision Loss in a Young Returning Traveler with Dengue Fever. (Pubmed Central) -  Dec 1, 2020   
    Vision improved, and the patient showed full recovery at 9 months after the onset. This case highlights the importance of awareness and adequate management for ocular involvement in patients with dengue fever, including travelers.
  • ||||||||||  prednisolone / Generic mfg., albendazole / Generic mfg.
    Journal:  Ocular Sparganosis: The First Report of Spirometra ranarum in Thailand. (Pubmed Central) -  Dec 1, 2020   
    The result from the sequencing of the PCR-amplified cox1 fragments in this study showed 99.0% sequence homology to Spirometra ranarum. This is the first report of S. ranarum in Thailand.
  • ||||||||||  prednisolone / Generic mfg.
    Journal:  A life-threatening complication due to pulmonary haemorrhage following hump-nosed viper bite. (Pubmed Central) -  Nov 28, 2020   
    This case highlights the importance of suspecting pulmonary haemorrhage in a patient who develops desaturation and alveolar shadow following hump-nosed viper bite even in the absence of other bleeding manifestation. Early and timely treatment with systemic steroid can be lifesaving in such patients.
  • ||||||||||  prednisolone / Generic mfg.
    Clinical, Journal:  Effectivness of Nebulized Budesonide for COPD Exacerbation Management in Emergency Department; a Randomized Clinical Trial. (Pubmed Central) -  Nov 28, 2020   
    This study aimed to compare the effectiveness of nebulized budesonide (NB) versus oral prednisolone (OP) in increasing peak expiratory flow rate (PEFR) of COPD patients in emergency department (ED)...Vital signs and VBG results showed no significant differences between the two groups during the studied time interval. NB, compared to OP, could more effectively increase PEFR and ameliorate disease severity of patients with COPD exacerbation at 12 and 24 hours after treatment in ED.
  • ||||||||||  prednisolone / Generic mfg.
    Clinical, Journal:  Prevalence and clinical associations with premature ovarian insufficiency, early menopause, and low ovarian reserve in systemic sclerosis. (Pubmed Central) -  Nov 28, 2020   
    The factors associated with early menopause were long disease duration (p = 0.02), high cumulative dose of CYC (p = 0.03), and high cumulative dose of prednisolone (p = 0.02)...Key Points • POI is revealed in patients with SSc particularly in who received high cumulative dose of cyclophosphamide, while early menopause and low ovarian reserve were major reproductive problem among SSc. • Prescriptions for CYC for female SSc-both for young patients of reproductive age and premenopausal middle-aged women-should be concerned of the long-term effects on gonadal function.
  • ||||||||||  prednisolone / Generic mfg., hydrocortisone / Generic mfg.
    Clinical, Journal:  Avascular necrosis of the femoral head due to low-dose corticosteroid used in a patient with panhypopituitarism: A case report and literature review. (Pubmed Central) -  Nov 28, 2020   
    In this article, we report a 34-year-old male patient with hypopituitarism who developed bilateral AVN while receiving a mild physiological replacement oral prednisolone dose for only three years for secondary adrenal insufficiency of hypopituitarism after transsphenoidal surgery...The case report intends to highlight the occurrence of AVN of the femur even with a very low dose of corticosteroid used for the treatment of panhypopituitarism. Avascular necrosis should be considered in the differential diagnosis in patients with hip pain, even in low-dose steroid use because early diagnosis is essential to prevent progression, collapse, and eventually the need for hip replacement in AVN.
  • ||||||||||  Humira (adalimumab) / Eisai, AbbVie
    Journal:  COVID-19 pandemic and biological therapy in rheumatologic disorders: how to deal with? (Pubmed Central) -  Nov 28, 2020   
    The use of biologic agents and DMARDs in rheumatic patients is a serious challenge in the COVID-19 pandemic. In conclusion, during the COVID-19 pandemic, due to the key roles of cytokines in the promotion of the disease, the rheumatic patients may benefit from continuing their previous treatment, which may have protective effects.
  • ||||||||||  prednisolone / Generic mfg., vigabatrin / Generic mfg.
    [VIRTUAL] Use of gamma-delta modulation index to predict and measure response to treatment for infantile spasms () -  Nov 28, 2020 - Abstract #AES2020AES_628;    
    Further study is needed to validate these findings and evaluate this novel EEG metric against other clinical and computational EEG measures. Funding: This study was accomplished with support from the Susan S. Spencer Clinical Research Training Scholarship from the American Academy of Neurology, the Pediatric Victory Foundation, the Sudha Neelakantan & Venky Harinarayan Charitable Fund, the Elsie and Isaac Fogelman Endowment, the Mohammed F. Alibrahim Endowment, the Hughes Family Foundation, the John C. Hench Foundation, the University of California Los Angeles Children’s Discovery and Innovation Institute, and UCB Biopharma.
  • ||||||||||  prednisolone / Generic mfg.
    [VIRTUAL] The COVID-19 pandemic - Research Priorities for Children with Epilepsy () -  Nov 28, 2020 - Abstract #AES2020AES_318;    
    In addition, there may be unique opportunities to use observational techniques to study the comparative effectiveness of medications in cases where the pandemic has led to changes in clinical practice. Post-study review suggests health equity particularly resonated with participants as a key outcome for future research.
  • ||||||||||  Rituxan (rituximab) / Biogen, Zenyaku Kogyo, Roche, Lemtrada (alemtuzumab) / Sanofi
    [VIRTUAL] A case of adult Still’s disease in an alemtuzumab-treated multiple sclerosis patient () -  Nov 28, 2020 - Abstract #DGN2020DGN_438;    
    The current case highlights AOSD as another rare and potentially life-threatening secondary autoinflammatory/autoimmune event following alemtuzumab treatment. Thorough clinical follow-up and early intense interdisciplinary communication and intervention are necessary in suspicious cases after treatment with alemtuzumab.
  • ||||||||||  prednisolone / Generic mfg.
    Biomarker, Journal:  mRNAs in urinary nano-extracellular vesicles as potential biomarkers for non-invasive kidney biopsy. (Pubmed Central) -  Nov 27, 2020   
    Treatment with prednisolone mitigated these changes in gene expression as well as proteinuria...These results suggest that changes in mRNA levels of urinary NVs reflect the disease status of kidney tissues and their functional alterations. Collectively, mRNA analysis of urinary NVs may be used as a liquid biopsy tool for improved classification and performance of risk prediction to determine the severity of kidney diseases.
  • ||||||||||  prednisolone / Generic mfg.
    Journal:  Steroids as rescue therapy for vitamin A-induced acute liver failure. (Pubmed Central) -  Nov 26, 2020   
    One of the chief components of these drugs is beta-carotene, and vitamin A. Vitamin A is a proven hepatotoxic agent which can lead to liver injury ranging from acute hepatitis to cirrhosis. Here, we present a case of chronic pancreatitis who continued antioxidant therapy unsupervised for 7 years and developed vitamin A-induced acute liver failure, which was treated with prednisolone.
  • ||||||||||  Rituxan (rituximab) / Biogen, Zenyaku Kogyo, Roche
    Clinical, Retrospective data, Journal, Real-World Evidence:  Dose-adjusted EPOCH with or without rituximab for aggressive lymphoma patients: real world data. (Pubmed Central) -  Nov 26, 2020   
    In newly diagnosed diffuse large B-cell lymphoma-not otherwise specified patients (n = 46), the CR rate was 80% (95% CI 64-91%) and the 2-year OS rate was 81% (95% CI 66-90%). In the present study, DA-EPOCH -/+ R exhibited excellent efficacy and feasibility for aggressive lymphoma.
  • ||||||||||  everolimus / Generic mfg., tacrolimus / Generic mfg.
    Clinical, Journal:  Arteriovenous graft in kidney transplant patients: Lookout for the rare but fearsome angiosarcoma. (Pubmed Central) -  Nov 25, 2020   
    We present the case of a 55-year-old female with history of kidney transplantation, immunosuppressed with tacrolimus, prednisolone, and mofetil mycophenolate...Histology was compatible with a high grade angiosarcoma that invaded the margins, and immunosuppression was switched to everolimus...Although rare, angiosarcoma is an important entity that should be considered in the differential diagnosis of soft tissue masses arising from a vascular access, especially in immunocompromised patients. Aggressive treatment should be offered whenever possible.
  • ||||||||||  Rituxan (rituximab) / Biogen, Zenyaku Kogyo, Roche
    Journal:  Type B insulin resistance syndrome (Pubmed Central) -  Nov 25, 2020   
    Mixed and transient results were seen with rituximab, mycophenolic acid and bortezomib but glycemic control has remained suboptimal. Lack of compliance and recurrent infections may have contributed to this.
  • ||||||||||  Trial completion date:  DETECT: Descemet Endothelial Thickness Comparison Trial (clinicaltrials.gov) -  Nov 25, 2020   
    P4,  N=38, Active, not recruiting, 
    Lack of compliance and recurrent infections may have contributed to this. Trial completion date: May 2020 --> May 2023