budesonide / Generic mfg. 
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  • ||||||||||  budesonide / Generic mfg., enoxaparin sodium / Generic mfg.
    PROTEIN LOSING ENTEROPATHY (PLE) EXACERBATION AFTER HEART TRANSPLANT IN A FONTAN: THINK OUTSIDE THE BOX (HEART)! (Poster Hall_Hall F) -  Jan 4, 2023 - Abstract #ACCWCC2023ACC_WCC_1821;    
    Heart transplantation reverses most of the physiologic abnormalities of the Fontan circulation and we often see resolution of PLE within 1 year of transplantation. Our case highlights that worsening PLE after heart transplant in a Fontan patient should alert the caregivers to assess for venous anastomotic site stenosis and that addressing it leads to complete resolution
  • ||||||||||  budesonide / Generic mfg., loperamide / Generic mfg.
    Journal:  Fecal calprotectin - a valuable predictor of microscopic colitis. (Pubmed Central) -  Jan 3, 2023   
    Measures to improve quality of life, should be of prime concern. In-depth research is required to better understand MC and to find better treatment options which can be used on a long-term basis, instead of anti-motility drugs which are able to control the acute episodes, but when discontinued result in an increased tendency to have relapses.
  • ||||||||||  budesonide / Generic mfg.
    Journal:  New insights into the mucosal immune pathogenesis of IgA nephropathy from the perspective of COVID-19 vaccination. (Pubmed Central) -  Jan 3, 2023   
    Budesonide treatment of IgAN is thought to inhibit intestinal immune response by binding to glucocorticoid receptors in the intestinal mucosa or submucosa, however, it is unclear whether there is a therapeutic effect in respiratory mucosa-derived IgA nephropathy. The present review firstly described the relationship between the gut and respiratory mucosa, and the differences in antigen-presenting cell activation pathways and B-cell homing from the perspective of COVID-19 vaccines.
  • ||||||||||  budesonide / Generic mfg.
    Journal:  Treatment of laryngeal pathology associated with gastroesophageal reflux disease (Pubmed Central) -  Dec 30, 2022   
    The present review firstly described the relationship between the gut and respiratory mucosa, and the differences in antigen-presenting cell activation pathways and B-cell homing from the perspective of COVID-19 vaccines. Indications for the appointment of inhaled anti-inflammatory therapy in patients with reflux-associated pathology of the larynx are the presence of complaints of hoarseness, dryness, tickling, lump in the throat and chronic cough, endolaryngoscopic signs of exacerbation of chronic inflammation of the mucous membrane of the posterior larynx.
  • ||||||||||  Skyrizi (risankizumab) / AbbVie, Boehringer Ingelheim
    Journal:  Risankizumab (Skyrizi) - An IL-23 antagonist for Crohn's disease. (Pubmed Central) -  Dec 22, 2022   
    FCBD:std and diclofenac exhibit synergistic anti-inflammatory effects on macrophages and lung epithelial cells, yet this combined activity needs to be examined in pre-clinical studies and clinical trials. No abstract available
  • ||||||||||  prednisone / Generic mfg., budesonide / Generic mfg.
    Assessment of Corticosteroid Use as a Marker of Quality-of-Care in the Management of Inflammatory Bowel Disease () -  Dec 9, 2022 - Abstract #AIBD2022AIBD_301;    
    Sixty-six percent of patients have received corticosteroids during the course of their disease (range 1-9 times) for a median of 12 weeks (2-48 weeks), prednisone being the most frequently used corticosteroid (53%). Seventy-seven percent of patients have received treatment for >3 months or in supratherapeutic doses (more than 1 mg/Kg, range 40-60 mg of prednisone).
  • ||||||||||  budesonide / Generic mfg.
    Journal:  Caffeic Acid-Conjugated Budesonide-Loaded Nanomicelle Attenuates Inflammation in Experimental Colitis. (Pubmed Central) -  Dec 7, 2022   
    The treatment with BUD-loaded micelles alleviates the colitis severity as analyzed in histopathology and efficiently, overcoming the disease severity via downregulation of various related cytokines (MPO, NO, and TNF-α) and inflammatory enzymes such as COX-2 and iNOS. Results of the study suggest that BUD-loaded nano-sized micelles effectively attenuate the disease conditions in colitis.
  • ||||||||||  mycophenolate mofetil / Generic mfg.
    Retrospective data, Journal:  Mycophenolate mofetil as second line treatment in autoimmune hepatitis - A retrospective single center analysis. (Pubmed Central) -  Dec 2, 2022   
    Most patients with autoimmune hepatitis respond to standard treatment with steroids and azathioprine...Patients treated with MMF because of intolerance to first line treatment show a good disease control under MMF in the majority of cases. Efficacy is considerably lower in the patients switched to MMF because of an insufficient response to first line treatment.
  • ||||||||||  budesonide / Generic mfg.
    Review, Journal:  Esophageal lichen planus: Current knowledge, challenges and future perspectives. (Pubmed Central) -  Nov 22, 2022   
    Timely diagnosis and therapy might prevent potential sequelae such as esophageal stenosis or development of invasive squamous cell carcinoma. Further studies are needed to gain more knowledge about the pathogenesis and treatment options.
  • ||||||||||  budesonide / Generic mfg., azathioprine / Generic mfg.
    Biomarker, Review, Journal:  Non-Invasive Biomarkers for the Diagnosis and Management of Autoimmune Hepatitis. (Pubmed Central) -  Nov 16, 2022   
    We also discuss biomarkers relevant to AIH from other immune diseases. We conclude with proposed future directions in which biomarker implementation into clinical practice could lead to advances in personalized therapeutic management of AIH.
  • ||||||||||  budesonide / Generic mfg.
    Journal:  Stabilization of cell-cell adhesions prevents symmetry breaking and locks in pluripotency in 3D gastruloids. (Pubmed Central) -  Nov 15, 2022   
    This correlates with reduced phenotypic and molecular cell heterogeneity, persistence of E-CADHERIN at the cell-cell interface, and cell aggregate compaction. Our findings reveal that cell-cell adhesion properties control symmetry breaking and cell fate transition in 3D gastruloids and suggest a potential adverse effect of budesonide on embryo development.
  • ||||||||||  budesonide / Generic mfg.
    Review, Journal:  Corticosteroids in Inflammatory Bowel Disease: Are they still a therapeutic option? (Pubmed Central) -  Nov 15, 2022   
    This review article is not intended to be just a classic review of the indications for corticosteroids. Here we explain the scenarios in which, in our opinion, steroids would not be an appropriate option for our patients, as well as the most frequent mistakes we make in our daily practice when using them.
  • ||||||||||  budesonide / Generic mfg.
    Enrollment open:  Budesonide Prophylaxis for Engraftment Syndrome After Hematopoietic Cell Transplantation (clinicaltrials.gov) -  Nov 14, 2022   
    P3,  N=110, Recruiting, 
    Here we explain the scenarios in which, in our opinion, steroids would not be an appropriate option for our patients, as well as the most frequent mistakes we make in our daily practice when using them. Not yet recruiting --> Recruiting
  • ||||||||||  vancomycin / Generic mfg., budesonide / Generic mfg.
    Review, Journal:  Microscopic colitis, a forgotten condition: a clinical case and review of the literature. (Pubmed Central) -  Nov 1, 2022   
    No abstract available This case study shows how actual diagnosis may be delayed not only due to having to perform differential diagnosis with chronic inflammatory diseases, but also because certainty can only come from histological evidence, which takes time to obtain, especially when the disease's multifactorial nature is considered (smoking, NSAID abuse, oral proton pump inhibitors, inappropriate antibiotic use, and Clostridium difficilis infection).
  • ||||||||||  budesonide / Generic mfg., carbimazole / Generic mfg., azathioprine / Generic mfg.
    Journal:  Autoimmune hepatitis in monozygotic twins - a case report. (Pubmed Central) -  Nov 1, 2022   
    This case study shows how actual diagnosis may be delayed not only due to having to perform differential diagnosis with chronic inflammatory diseases, but also because certainty can only come from histological evidence, which takes time to obtain, especially when the disease's multifactorial nature is considered (smoking, NSAID abuse, oral proton pump inhibitors, inappropriate antibiotic use, and Clostridium difficilis infection). This case report supports the hypothesis that a genetic factor might be of great importance in the aetiology of autoimmune hepatitis.
  • ||||||||||  prednisone / Generic mfg., budesonide / Generic mfg.
    Clinical guideline, Review:  AGA Clinical Practice Update on Management of Refractory Celiac Disease: Expert Review. (Pubmed Central) -  Oct 26, 2022   
    Identify local experts with expertise in celiac disease to assist with management. BEST PRACTICE ADVICE 10: Patients with refractory celiac disease without response to steroids may benefit from referral to a center with expertise for management or evaluation for inclusion in clinical trials.
  • ||||||||||  budesonide / Generic mfg.
    Trial initiation date:  Budesonide Prophylaxis for Engraftment Syndrome After Hematopoietic Cell Transplantation (clinicaltrials.gov) -  Oct 25, 2022   
    P3,  N=110, Not yet recruiting, 
    BEST PRACTICE ADVICE 10: Patients with refractory celiac disease without response to steroids may benefit from referral to a center with expertise for management or evaluation for inclusion in clinical trials. Initiation date: Sep 2022 --> Dec 2022