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20 Diseases |  |
17 Trials |
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17 Trials |  |
3666 News |  |
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- || Stelara (ustekinumab) / J&J, Entyvio (vedolizumab) / Takeda
Clinical, Review, Journal: A Personalized Approach to Managing Patients With an Ileal Pouch-Anal Anastomosis. (Pubmed Central) - Feb 19, 2020
Primary sclerosing cholangitis-associated CARP can be treated with budesonide or oral vancomycin...Vedolizumab and ustekinumab are the preferred first- and second-line biologics for autoimmune CARP owing to their efficacy, better side effect profile, and low immunogenicity and need for concomitant immunomodulatory therapy...Incidence varies based on a patient's risk. Since incidence is low, a risk-stratified approach is recommended.
- | budesonide / Generic mfg., budesonide/salbutamol (PT027) / AstraZeneca, Avillion
Journal: An occupational exposure limit (OEL) approach to protect home healthcare workers exposed to common nebulized drugs. (Pubmed Central) - Feb 16, 2020
We developed risk-based exposure limits for workers in the form of occupational exposure limits (OEL) values for exposure to nebulized forms of the three most common drugs administered by this albuterol, ipratropium, and budesonide...These OELs were derived based on human effect data and adjusted for pharmacokinetic variability and areas of uncertainty relevant to the underlying data (human and non-human) available for each drug. The resulting OEL values provide an input to the occupational risk assessment process to allow for comparisons to HHCW exposure that will guide risk management and exposure control decisions.
- ||| Asacol (5ASA) doesn’t work in Crohns. Only for Ulcerative colitis. Also for UC Rx infliximab adalimumab golimumab ustekinumab vedolizumab and small molecules ex sulfasalazine steroids incl budesonide Azathioorine tofacitinib. @rheumnow @RWCSmtg #RWCS2020 (Twitter) - Feb 15, 2020
- | budesonide / Generic mfg.
Journal: Surfactant plus budesonide decreases lung and systemic inflammation in mechanically ventilated preterm sheep. (Pubmed Central) - Feb 14, 2020
The resulting OEL values provide an input to the occupational risk assessment process to allow for comparisons to HHCW exposure that will guide risk management and exposure control decisions. In ventilated preterm lambs, most of the budesonide left the lung within 24 h. The addition of budesonide to surfactant improved physiology, decreased markers of lung injury, and decreased systemic responses in liver and brain.
- duloxetine delayed release / Generic mfg.
Smoking Cessation and Duloxetine Toxicity: A Case Report () - Feb 11, 2020 - Abstract #ISPRM2020ISPRM_1573;
Patient was stabilized and continued his home medications including amiodarone, digoxin, carvedilol, spironolactone, sacubitril/valsartan, aspirin, clopidogrel, warfarin, tiotropium, budesonide, finasteride, and duloxetine...After LVAD placement, he continued to have myoclonus despite increased levetiracetam and clonazepam...Although computerized surveillance systems alert clinicians of interactions when an offending drug is introduced, they do not alert when a drug is discontinued. It is crucial to remember to not rely solely on these systems, as the lack of proper medication reconciliation can lead to devastating outcomes.
- | budesonide / Generic mfg., Aerospan (flunisolide HFA) / Allergan, Mylan
Journal: Molecular Dissection of an Inhibitor Targeting the Hiv Integrase Dependent Pre-Integration Complex Nuclear Import. (Pubmed Central) - Feb 9, 2020
Significantly, Budesonide or its analogue Flunisolide, were able to effect a significant reduction in the presence of specific nuclear forms of the HIV DNA (2-LTR circles), suggesting that the inhibitors work though blocking IN, and potentially PIC, nuclear import. The work presented here represents a platform for further development of these specific inhibitors of HIV replication with therapeutic and prophylactic potential.
- || budesonide / Generic mfg.
Clinical, Review, Journal: Inhaled corticosteroids in children with persistent asthma: effects of different drugs and delivery devices on growth. (Pubmed Central) - Feb 9, 2020
However, the evidence from this systematic review of head-to-head trials is not certain enough to inform the selection of inhaled corticosteroid or inhalation device for the treatment of children with persistent asthma. Further studies are needed, and pragmatic trials and real-life observational studies seem more attractive and feasible.
- Jakafi oral (ruxolitinib) / Novartis, Incyte
[VIRTUAL] LOW-DOSE OF RUXOLITINIB: AN EFFECTIVE THERAPY FOR REFRACTORY BOS PATIENTS (ePoster Area) - Feb 8, 2020 - Abstract #EBMT2020EBMT_1237;
Physicians should pay attention to symptoms and monitor PFT. Combination therapy with low-dose of Ruxolitinib has obvious curative effects on refractory BOS patients.
- || budesonide / Generic mfg.
Clinical, Journal, Real-World Evidence: Effectiveness and Patient Satisfaction with Budesonide/Formoterol Easyhaler Among Patients with Asthma or COPD Switching from Previous Treatment: a Real-World Study of Patient-Reported Outcomes. (Pubmed Central) - Feb 8, 2020
Patients with asthma or COPD who switched to B/F Easyhaler from their previous inhaler due to lack of disease control achieved significant improvements in symptoms and disease control, HRQoL, and lung function within 12 weeks of real-world use with significant increase in patient satisfaction also observed. Such comparative information may reassure clinicians and patients that may be viewed as an appropriate and potentially beneficial treatment option.
- || budesonide / Generic mfg.
I am a little worried since he had gotten so anemic. Budesonide taper reasonable with regular monitoring of CBC, if he drops again then VDZ or UST (Twitter) - Jan 31, 2020
- || budesonide / Generic mfg.
I kind of like the do nothing idea, even if he had some brewing inflam ongoing for 5y clearly it was mild and not progressing. He’s 82 so pros/cons of therapies should be considered. How about 1-2m course of Budesonide, follow response with FCP to try to get him off iron? (Twitter) - Jan 31, 2020
- | budesonide / Generic mfg.
Journal: Budesonide Suppositories are Effective and Safe for Treating Acute Ulcerative Proctitis. (Pubmed Central) - Jan 30, 2020
P2
Budesonide suppositories offer an alternative therapy to mesalamine for topical treatment of proctitis. Clinicaltrialsregister.eu no: 2012-003362-41.
- |||| budesonide / Generic mfg.
Trial completion date, Trial primary completion date: To Evaluate the Efficacy and Safety of FE 999315 in Japanese Subjects With Mild to Moderate Active Ulcerative Colitis (clinicaltrials.gov) - Jan 30, 2020
P3, N=273, Recruiting, Sponsor: Ferring Pharmaceuticals
Clinicaltrialsregister.eu no: 2012-003362-41. Trial completion date: Jan 2020 --> May 2020 | Trial primary completion date: Jan 2020 --> May 2020
- || Breztri Aerosphere (budesonide/formoterol fumarate/glycopyrronium) / AstraZeneca, Bevespi Aerosphere (formoterol/glycopyrrolate) / AstraZeneca
Clinical, Journal: Bone and ocular safety of budesonide/glycopyrrolate/formoterol fumarate metered dose inhaler in COPD: a 52-week randomized study. (Pubmed Central) - Jan 29, 2020
P3
Changes from baseline in all three treatment groups over 52 weeks were small and not clinically meaningful. All treatments were well tolerated with no new or unexpected safety findings.
- || Veramyst (fluticasone furoate nasal spray) / GSK
Retrospective data, Review, Journal: Epistaxis Risk Associated with Intranasal Corticosteroid Sprays: A Systematic Review and Meta-analysis. (Pubmed Central) - Jan 29, 2020
All treatments were well tolerated with no new or unexpected safety findings. While a differential effect on epistaxis among INCS agents is not clearly demonstrated, this meta-analysis does confirm an increased risk of epistaxis for patients using INCSs as compared with placebo for treatment of allergic rhinitis.
- || methylprednisolone oral / Generic mfg., Rituxan (rituximab) / Roche, Biogen
Clinical, Journal: Successful Treatment of Veno-occlusive Disease, Transplantation-Associated Thrombotic Microangiopathy, and Acute Graft-vs-Host Disease in a Patient with Relapsed Epstein-Barr Hemophagocytic Lymphohistiocytosis After Haploidentical Hematopoietic Stem Cell Transplantation: A Case Report. (Pubmed Central) - Jan 28, 2020
Epstein-Barr virus related-HLH patients have severe clinical features and currently poor prognosis. Allogenic hematopoietic stem cell transplantation may be the best way to treat this disease; however, the management of related complications is vital in the improvement of long-term survival.
- budesonide / Generic mfg.
UTILITY OF MAJOR BASIC PROTEIN, EOTAXIN-3, AND MAST CELL TRYPTASE STAINING FOR PREDICTION OF RESPONSE TO TOPICAL STEROID TREATMENT IN EOSINOPHILIC ESOPHAGITIS: ANALYSIS OF A RANDOMIZED, DOUBLE-BLIND, DOUBLE-DUMMY CLINICAL TRIAL () - Jan 28, 2020 - Abstract #DDW2020DDW_2985;
P4
While there are some trends, and while elevated mast cell TRP levels may be associated with non-response compared with complete response (no eosinophils), the magnitude and predictive utility is modest. Novel methods for predicting steroid response are still required.
- budesonide / Generic mfg., Carafate (sucralfate) / Allergan
TREATMENT OF LYMPHOCYTIC ESOPHAGITIS IN A LARGE TERTIARY ACADEMIC INSTITUTION () - Jan 28, 2020 - Abstract #DDW2020DDW_2972;
Baseline characteristics are described in Table 1. Thirty (68%) of patients were treated with a proton pump inhibitor (PPI), 5 (11%) with PPI and sucralfate, 3 (7%) with PPI and Budesonide, 2 (5%) with Budesonide, and 4 (9%) with ranitidine.
- budesonide / Generic mfg.
STRONG ASSOCIATION BETWEEN DYSPHAGIA FREQUENCY WITH DAILY OR WEEKLY RECALL IN ADULTS WITH EOSINOPHILIC ESOPHAGITIS: ANALYSIS OF TWO SYMPTOM-BASED PATIENT-REPORTED OUTCOME MEASURES USED IN A COMPARATIVE EFFICACY RANDOMIZED TRIAL () - Jan 28, 2020 - Abstract #DDW2020DDW_2971;
Esophageal dilation eliminated the positive correlation between dysphagia and esophageal eosinophil count. This suggests that weekly recall can be used in prospective studies of EoE, but that dilation status needs to be carefully addressed in study design and analysis.
- budesonide oral (TAK-721) / Takeda
PREDICTORS OF RESPONSE TO CORTICOSTEROID THERAPY IN PATIENTS WITH EOSINOPHILIC ESOPHAGITIS: RESULTS FROM A PHASE 3, RANDOMIZED, PLACEBO-CONTROLLED TRIAL OF BUDESONIDE ORAL SUSPENSION () - Jan 28, 2020 - Abstract #DDW2020DDW_2962;
P3
Less severe dysphagia at baseline, as measured by the DSQ, may be associated with an increased likelihood of having a histologic or symptom response to BOS. Further analyses examining clinical features and biomarkers may provide additional insights into factors that predict response to corticosteroids; these findings may help inform the optimal management of patients with EoE.
- budesonide / Generic mfg.
DYSPHAGIA IN EOSINOPHILIC ESOPHAGITIS IMPROVES WITH TOPICAL STEROID TREATMENT INDEPENDENT OF IMPROVEMENT IN ENDOSCOPIC AND HISTOLOGIC MEASURES OF MUCOSAL INFLAMMATION: ANALYSIS OF A RANDOMIZED COMPARATIVE EFFECTIVENESS CLINICAL TRIAL. () - Jan 28, 2020 - Abstract #DDW2020DDW_2938;
In a randomized, comparative clinical trial comparing fluticasone metered dose inhaler to budesonide slurry for 8-weeks treatment of newly diagnosed EoE, dysphagia symptoms, endoscopic appearance, and overall peak eosinophil count all significantly improved, but improvement in symptoms was independent of improvement of endoscopic and histologic measures of mucosal inflammation. This suggests that all three outcomes – symptoms, endoscopy, and histology are needed to adequately capture patient experience and diseases severity.
- budesonide / Generic mfg.
DETERMINATION OF AN ENDOSCOPIC RESPONSE THRESHOLD FOR THE EOSINOPHILIC ESOPHAGITIS ENDOSCOPIC REFERENCE SCORE: ANALYSIS OF A RANDOMIZED COMPARATIVE CLINICAL TRIAL OF TOPICAL STEROIDS. () - Jan 28, 2020 - Abstract #DDW2020DDW_2937;
With this empiric approach, an EREFS of two or lower was associated with well-controlled disease activity and could be considered the threshold for endoscopic response to topical steroid therapy. EREFS of three or four could be considered partial response, and ERES of five or above could be considered non-response.
- budesonide / Generic mfg.
COMPOUNDED FLUTICASONE SLURRY IS AN EFFECTIVE THERAPY AND REDUCES SYMPTOMS IN EOSINOPHILIC ESOPHAGITIS () - Jan 28, 2020 - Abstract #DDW2020DDW_2934;
Compounded fluticasone provided a significant reduction in symptoms, with greater than half reporting global improvement, and eosinophilia, with more than a third achieving histologic response, in an EoE population that was largely treatment refractory. This formulation may provide an alternative therapy in the armamentarium for EoE treatments.
- budesonide / Generic mfg.
OUTCOMES OF LOWER DOSING OF BUDESONIDE FOR MAINTENANCE THERAPY IN MICROSCOPIC COLITIS () - Jan 28, 2020 - Abstract #DDW2020DDW_2928;
More patients in the lower dose group were on NSAID/aspirin therapy at diagnosis, suggesting that cessation of NSAIDs/aspirin in most of these patients led to decreased budesonide requirement long term. Adjunct therapies including bile acid sequestrants and anti-diarrheal agents can also aid in long term steroid-sparing.
- PATIENT REPORTED OUTCOMES: THE ICHOM STANDARD SET FOR IBD IN REAL LIFE PRACTICE HELPS QUANTIFY DEFICITS IN CURRENT CARE () - Jan 28, 2020 - Abstract #DDW2020DDW_2670;
(adalimumab 13%, golimumab <1%, infliximab 9%, tofacitinib 1%, ustekinumab 1%, vedolizumab 16%)...Conclusion Outcomes reported by patients illustrate the scale of the therapeutic deficit in current care. The ICHOM Standard Set acts as a benchmark for comparing outcomes between institutions
- budesonide / Generic mfg., methotrexate / Generic mfg., azathioprine orodispersible / Generic mfg.
CHARACTERISTICS OF SKIN LESIONS ASSOCIATED WITH ANTI-TUMOR NECROSIS FACTOR THERAPY OR OTHER BIOLOGIC AGENTS IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE: A PROSPECTIVE COHORT STUDY () - Jan 28, 2020 - Abstract #DDW2020DDW_2540;
Atopic dermatitis, acneiform dermatoses and psoriasiform eczema are the most common presentations. While early referral to a dermatologist is recommended, most lesions can be managed by topical treatment and discontinuation of biologic is rarely required
- budesonide oral (TAK-721) / Takeda
BUDESONIDE ORAL SUSPENSION (BOS) IMPROVES ENDOSCOPIC ACTIVITY IN ADOLESCENTS AND ADULTS WITH EOSINOPHILIC ESOPHAGITIS: RESULTS AND CORRELATION ANALYSIS FROM A PHASE 3, RANDOMIZED, PLACEBO-CONTROLLED TRIAL () - Jan 28, 2020 - Abstract #DDW2020DDW_2258;
P3
This trial met its predefined co-primary, key secondary and secondary endpoints. BOS treatment led to significant improvements from baseline to week 12 versus placebo in EREFS and histologic and symptom responses.
- | Xeljanz (tofacitinib) / Pfizer
Journal: Gastroenterology and hepatology in 2019 (Pubmed Central) - Jan 28, 2020
Aspirin appears to prevent fibrotic lesions in NALFD...The role of carvedilol is confirmed in the TT of portal hypertension...Tofacitinib is an effective molecule in ulcerative colitis but precautions are needed. Budesonide tablet is validated for the TT of eosinophilic esophagitis.
- || valacyclovir / Generic mfg., budesonide / Generic mfg., Nimi-Rapitab (nimesulide) / Shreya Life Sciences
Clinical, Journal: PROSPECTIVE MONITORING OF DRUG USE: DRUG-INDUCED LIVER INJURY IN A PRIMARY HEALTHCARE CENTER. (Pubmed Central) - Jan 24, 2020
Drug-induced liver injury is rare in primary healthcare units. It also allowed estimating the incidence of hepatotoxicity induced by allopathic medicines which are standardized by public healthcare authorities.
- || budesonide / Generic mfg., budesonide/salbutamol (PT027) / AstraZeneca, Avillion
Clinical, Journal: Riesgo de caries dental en pacientes pediátricos asmáticos en tratamiento con la terapia inhalatoria de salbutamol y budesonida, Perú. (Pubmed Central) - Jan 24, 2020
Por lo tanto, el riesgo de caries dental en el grupo de casos fue alto en 50% (n=46) y en el grupo control fue moderado en 72,8% (n=67); p=0,001. Conclusión: El riesgo de caries dental en los pacientes asmáticos en tratamiento inhalatorio con salbutamol y budesonida es significativamente superior al de los pacientes sanos.
- | budesonide / Generic mfg.
Preclinical, Journal: Effect of asiaticoside on hyperoxia-induced bronchopulmonary dysplasia in neonatal rats and related mechanism (Pubmed Central) - Jan 24, 2020
Conclusión: El riesgo de caries dental en los pacientes asmáticos en tratamiento inhalatorio con salbutamol y budesonida es significativamente superior al de los pacientes sanos. Asiaticoside can alleviate inflammation injury induced by hyperoxia in neonatal rats and improve the symptoms of bronchopulmonary dysplasia in a dose-dependent manner, possibly by down-regulating the expression of miR-155 and up-regulating the expression of SOCS1.
- budesonide / Generic mfg.
Evaluation of the Response to Oral Budesonide by the New Histology Scoring System Developed for Eosinophilic Esophagitis Patients (LACC West Exhibit Hall A, Poster Board Number: 215) - Jan 24, 2020 - Abstract #USCAP2020USCAP_875;
BZH, SEA, and EI in proximal esophagus respond to BUD earlier and potentially can be used as predictors of response to treatment in EoE patients. Presence of LPF, BZH, and DIS in treated individuals with 0 eosinophils/hpf could justify continuous clinical symptoms in some treated patients with 0 eosinophils.
- budesonide / Generic mfg.
A Novel Presentation of Eosinophilic Gastrointestinal Disorders in Post-Intestinal Transplant Recipients: A Pediatric Case Series (LACC West Exhibit Hall A, Poster Board Number: 122) - Jan 24, 2020 - Abstract #USCAP2020USCAP_792;
While there are studies detailing normal eosinophil counts for various gastrointestinal sites, one limitation of our study is the absence of a defined criteria for eosinophil counts in the post-transplant setting. Further study of the incidence, risk factors, potential allograft complications and mechanism merits further evaluation.
- ||||| budesonide / Generic mfg.
Clinical: @DrSamirAShah1 Mesalamine no better than placebo for microscopic colitis; budesonide is effective #IBDSchool @AmCollegeGastro (Twitter) - Jan 24, 2020
- | budesonide / Generic mfg., Combivent (ipratropium/salbutamol) / Boehringer Ingelheim
Journal: Aerosol Characteristics and Physico-Chemical Compatibility of Combivent (Containing Salbutamol and Ipratropium Bromide) Mixed with Three Other Inhalants: Budesonide, Beclomethasone or N-Acetylcysteine. (Pubmed Central) - Jan 24, 2020
This indicates that the mixtures were physically and chemically compatible. The mixing did not influence the particle size, distribution, or delivery compatibility of the mixtures.
- |||| prednisone / Generic mfg., budesonide / Generic mfg.
Here are the data on bone density with systemic steroids compared with budesonide: Bottom line: if you start with prednisone, bone loss occurs early and you lose the benefit of budesonide. So always consider budesonide first if steroids are needed. #CCCongress20 #IBDAtoZ (Twitter) - Jan 23, 2020
- || budesonide / Generic mfg.
Clinical, Journal: Efficacy and predictors of response to inhaled corticosteroid treatment for chronic cough. (Pubmed Central) - Jan 21, 2020
Duration of cough and cough triggered by cold air exposure were the clinical factors associated with ICS response. Extended treatment with ICS may be beneficial in patients with long duration of cough.
- || budesonide / Generic mfg.
Retrospective data, Review, Journal: Histologic Healing Rates of Medical Therapies for Ulcerative Colitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. (Pubmed Central) - Jan 19, 2020
These data provide benchmarks to inform future trial design. Histologic remission is a potential treatment target in clinical practice.
- | New trial: The Effect of Oral Polymeric Diet Enriched With TGF-beta 2 (Modulen) on Clinical Response and Mucosal Healing in Adult Patients With Newly Diagnosed Crohn's Disease (clinicaltrials.gov) - Jan 18, 2020
P=N/A, N=50, Not yet recruiting, Sponsor: Hillel Yaffe Medical Center
- || budesonide / Generic mfg.
Clinical, Journal: Effect of ginger extract on expression of GATA3, T-bet and ROR-γt in peripheral blood mononuclear cells of patients with Allergic Asthma. (Pubmed Central) - Jan 16, 2020
Histologic remission is a potential treatment target in clinical practice. This study showed that the use of ginger extract could control asthma and decrease the severity of this disease by affecting the main cells involving the symptoms of asthma in the airways.
- || budesonide / Generic mfg.
Clinical, Journal, HEOR: Autoimmune hepatitis exerts a profound, negative effect on health related quality of life: a prospective, single centre study. (Pubmed Central) - Jan 10, 2020
HRQoL is significantly impaired in patients with AIH. Depression seems to be a dominant symptom affecting their well-being, not associated with clinical and biochemical features of the disease.
- | simvastatin / Generic mfg., donepezil / Generic mfg.
Journal, HEOR: Microscopic colitis impacts quality of life in older people. (Pubmed Central) - Jan 10, 2020
She was started on oral budesonide with improvement in the abdominal and bowel symptoms...The outcomes were an improved quality of life, reduced functional dependency, reduced carer strain and avoidance of premature transition from her home into a long-term/institutional care setting. We briefly review terminology, basic epidemiology, notable associations, the importance of establishing a diagnosis and some treatment considerations for MC.
- | budesonide / Generic mfg.
Journal: NGSEA: Network-Based Gene Set Enrichment Analysis for Interpreting Gene Expression Phenotypes with Functional Gene Sets. (Pubmed Central) - Jan 10, 2020
We, therefore, expect that NGSEA will facilitate both pathway interpretation of gene expression phenotypes and anti-cancer drug repositioning. NGSEA is freely available at www.inetbio.org/ngsea.
- | budesonide / Generic mfg.
Journal: Low-Dose Budesonide/Formoterol Counteracts Airway Inflammation and Improves Lung Function in COPD. (Pubmed Central) - Jan 9, 2020
NGSEA is freely available at www.inetbio.org/ngsea. No abstract available
- | budesonide / Generic mfg.
Preclinical, Journal: Glucocorticoid-driven transcriptomes in human airway epithelial cells: commonalities, differences and functional insight from cell lines and primary cells. (Pubmed Central) - Jan 8, 2020
Furthermore, positive and negative effects on signaling, proliferation, migration and apoptosis were revealed. Since many such gene expression changes occurred in human airways post-ICS inhalation, the effects observed in cell lines and primary HBE cells in vitro may be relevant to ICS in vivo.
- || budesonide / Generic mfg., budesonide ER / Generic mfg.
Clinical, Journal: Budesonide MMX: efficacy and safety profile in the treatment of ulcerative colitis. (Pubmed Central) - Jan 8, 2020
Expert opinion: Budesonide MMX is a novel formulation that uses a Multi-Matrix System (MMX) technology to facilitate the release of high concentrations of active drug into the colon. Budesonide MMX at the dose of 9 mg/day for 8 weeks is effective and safe in inducing clinical and endoscopic remission in patients with mild to moderate UC, who had an inadequate response or were intolerant to either first line conventional therapy with topical and oral 5-aminosalicylic acid.
- || Veramyst (fluticasone furoate nasal spray) / GSK
Clinical, Review, Journal: Long-term use of inhaled glucocorticoids in patients with stable chronic obstructive pulmonary disease and risk of bone fractures: a narrative review of the literature. (Pubmed Central) - Jan 8, 2020
The exact relationship between long-term ICS use and bone fracture incidence in patients with stable COPD remains unclear in light of our review. We have, however, identified several limiting factors in existing studies that may form the basis of future RCTs designed specifically to explore this relationship.
- || budesonide / Generic mfg.
Clinical, Journal: Comparative analysis of medical expenditure with nebulized budesonide versus systemic corticosteroids in hospitalized patients with acute exacerbations of chronic obstructive pulmonary disease in China. (Pubmed Central) - Jan 8, 2020
This post-hoc analysis suggests that nBUD regimens are associated with lower medical expenditure than SCS regimens in hospitalized patients with AECOPD, and may reduce the financial burden of COPD. However, prospective studies evaluating the effectiveness of nBUD therapies are warranted.
- budesonide / Generic mfg., budesonide ER / Generic mfg.
A ‘real-world’ observational multi-centre study comparing the side effects and patient acceptability of budesonide MMX with prednisolone in patients with mild to moderate ulcerative colitis (Hall C - Poster exhibition) - Jan 7, 2020 - Abstract #ECCOIBD2020ECCO_IBD_1778;
In addition, budesonide MMX therapy was acceptable to the majority of patients and accompanying instructions easy to understand. Additional data will be presented.
- Comparative assessment of probiotics and standard therapies for mild to moderate ulcerative colitis: A systematic review and network meta-analysis (Hall C - Poster exhibition) - Jan 7, 2020 - Abstract #ECCOIBD2020ECCO_IBD_1645;
Probiotics were ranked the best tolerated option in terms of discontinuation due to adverse events (SUCRA 0.80).Conclusion Probiotics are well tolerated but they are not effective in inducing remission in active UC. They may be effective when added to mesalamine therapy in preventing relapse of quiescent UC, but large, well-designed RCTs are needed.