fentanyl citrate / Generic mfg. 
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  • ||||||||||  Observational data, Journal:  Use and misuse of psychoactive medicines: a descriptive cross-sectional study in a densely populated region of Portugal. (Pubmed Central) -  Jul 31, 2024   
    Chronic use of PMed was observed in 25%, especially with sertraline and buprenorphine for opioid use disorder (long-term treatment), and lorazepam (short-term treatment)...Risk of abuse was low for BZDR, whilst four opioids had meaningful doctor shopping indicators - fentanyl, opioid use disorder buprenorphine, morphine and hydromorphone...Prevalence of OA use is low, although with higher risk of misuse than BZDR. Concomitant use of several PMed is frequent.
  • ||||||||||  fentanyl citrate / Generic mfg., morphine sulphate / Generic mfg.
    Pharmaceutical Automated Reporting: An Opioid Stewardship Tool (Exhibit Hall) -  Jul 31, 2024 - Abstract #PAINWeek2024PAINWeek_207;    
    9%) patients with at least one opioid-related risk factor and 6590 (62. 4%) triggering multiple risk factors simultaneously.
  • ||||||||||  fentanyl citrate / Generic mfg., morphine sulphate / Generic mfg.
    Effects of morphine to fentanyl interchange in post-anesthesia care unit order sets (Exhibit Hall) -  Jul 31, 2024 - Abstract #PAINWeek2024PAINWeek_169;    
    Patients were screened for inclusion in reverse chronological order until 150 patients were included in both groups. Baseline characteristics were similar except more patients in the pre-intervention group received both fentanyl and morphine in the operating room.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Preclinical, Journal:  Increased risky choice during forced abstinence from fentanyl on the cued rat gambling task. (Pubmed Central) -  Jul 30, 2024   
    These findings complement those from human subjects, in whom preference for uncertain outcomes increased before relapse. These data highlight an abstinence-induced change in cognition that is unique to opiates as compared to psychostimulants, and which may critically contribute to the maintenance of addiction and relapse.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Journal:  Opioid-related deaths in Northern Ontario in the early COVID-19 pandemic period. (Pubmed Central) -  Jul 30, 2024   
    These data highlight an abstinence-induced change in cognition that is unique to opiates as compared to psychostimulants, and which may critically contribute to the maintenance of addiction and relapse. Differences between the circumstances of death in Northern ON and
  • ||||||||||  Retrospective data, Review, Journal:  Efficacy and Safety of Analgesics and Sedatives during Radiofrequency Catheter Ablation of Atrial Fibrillation: A Network Meta-Analysis. (Pubmed Central) -  Jul 30, 2024   
    In terms of safety, propofol (OR 16.46; 95% CI [1.54 to 175.95]) and midazolam plus fentanyl or its derivatives (OR 7.02; 95% CI [1.33 to 36.99]) significantly increased the incidence of respiratory depression compared with dexmedetomidine plus fentanyl or its derivatives...It is necessary to explore the regimen that can consider both the effectiveness and safety during radiofrequency catheter ablation for atrial fibrillation (AF). This study was registered with PROSPERO, number: CRD42023403661.
  • ||||||||||  fentanyl citrate / Generic mfg., methadone / Generic mfg.
    Journal:  Impact of COVID-19 on Drug Positivity Rates in the Emergency Departments in Boston and Surrounding Areas. (Pubmed Central) -  Jul 30, 2024   
    Our study showed that the COVID-19 pandemic significantly affected drug and alcohol positivity rates in patients presenting to the ED in greater Boston area. We encourage other institutions to perform similar analyses to help determine local drug use patterns and appropriate composition of UDS panels.
  • ||||||||||  fentanyl citrate / Generic mfg., dexamethasone injection / Generic mfg.
    Preclinical, Journal:  Understanding the Ocular Hypertension Model in Mice Induced by Dexamethasone-21-Acetate - Implications for Glaucoma Research. (Pubmed Central) -  Jul 26, 2024   
    This study aimed to assess the effectiveness of monocular and bilateral injections of Dexamethasone-21-acetate (Dex-21-Ac) into the murine fornix twice a week as a glucocorticoid-induced ocular hypertension model and investigated potential systemic side effects...Hepatic steatosis was observed in all Dex-21-Ac-treated animals, and some suffered from residual neuromuscular blockade under fentanyl anesthesia...Considering liver damage and associated influence on metabolization, hepatically eliminated injection anesthetics may lead to overdosing and are not recommended. They should be replaced by inhalation anesthesia.
  • ||||||||||  fentanyl citrate / Generic mfg., diphenhydramine / Generic mfg., methamphetamine / Generic mfg.
    Journal:  Drug Trends in the Teenage Postmortem Population From 2017 to 2021. (Pubmed Central) -  Jul 23, 2024   
    Methamphetamine- and cocaine-positive cases also increased 126% and 54%, with a net percent positivity of +0.6% and -0.5%, respectively...In addition to commonly misused drugs, trends for other substances that are prevalent in social media and therefore may disproportionally impact teens, MDMA/MDA, mitragynine, and diphenhydramine, were also assessed. A discussion of drug-related social media trends is presented to provide additional context for the data and trends reported herein, ultimately creating a framework through which social influences on teenage drug use can be better understood.
  • ||||||||||  Journal:  Postoperative opioid-free analgesia in dogs undergoing tibial plateau leveling osteotomy: a feasibility study. (Pubmed Central) -  Jul 22, 2024   
    After premedication with intravenous (IV) medetomidine (0.005-0.007?mg/kg) and midazolam (0.2?mg/kg), the dogs were anesthetized using ketamine (2?mg/kg) and propofol and maintained with isoflurane and ketamine CRI (0.6?mg/kg/h)...Meloxicam (0.2?mg/kg IV) was administered intraoperatively, after osteotomy...Total opioid-free postoperative analgesia was achieved in all dogs, with adequate recoveries. Although opioid-free anesthesia was feasible in 55% of the population, a single dose of fentanyl was necessary in 45% of the dogs during arthrotomy.
  • ||||||||||  Review, Journal:  Neuropsychiatric Effects Associated with Opioid-Based Management for Palliative Care Patients. (Pubmed Central) -  Jul 20, 2024   
    It is necessary, even lifesaving, to be cognizant of potential neuropsychiatric effects that opioids can have on an individual, especially for those under palliative care. By having an increased understanding and awareness of potential opioid neuropsychiatric effects, patient quality of life can be improved, healthcare system costs can be decreased, and patient outcomes can be met and exceeded.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Clinical, Review, Journal, Adverse events:  Perioperative analgesic efficacy and adverse events of fentanyl in dentistry: A systematic review. (Pubmed Central) -  Jul 20, 2024   
    While fentanyl demonstrated satisfactory perioperative analgesic efficacy, there were other alternatives that displayed better or comparable outcomes. Due to the risks and potential for misuse of fentanyl, these alternatives must be considered although adverse events were also reported.
  • ||||||||||  methamphetamine / Generic mfg.
    Journal:  A case of severe opioid and methamphetamine use disorder in a 14 year old. (Pubmed Central) -  Jul 20, 2024   
    Adjunctive treatment with CM may improve retention in MOUD and have the benefit of treating StUD. There is a need for further research to explore innovative, community-based treatment for youth with OUD.
  • ||||||||||  fentanyl citrate / Generic mfg., methamphetamine / Generic mfg.
    Journal:  A multi-analyte assay of opioids in API and drug products using HPLC and HRMS. (Pubmed Central) -  Jul 18, 2024   
    For all samples tested in the study, their identities were confirmed, and assays met specifications. Overall, there was no evidence of illegal substitution or adulteration in any of the ingredients and products tested from the legitimate commercial marketed US supply chain.
  • ||||||||||  fentanyl citrate / Generic mfg., diphenhydramine / Generic mfg., midazolam hydrochloride / Generic mfg.
    Journal:  Marijuana and Endoscopy: The effects of marijuana on sedation. (Pubmed Central) -  Jul 18, 2024   
    Marijuana use is associated with a significantly higher amount of sedation along with a significantly higher usage of other adjunct sedatives. A patient's marijuana history should be considered when determining the methods of sedation to be used for endoscopy.
  • ||||||||||  fentanyl citrate / Generic mfg., dexmedetomidine / Generic mfg.
    Comparison of Nociception Monitors in Opioid-based Versus Opioid-free Anesthesia for Craniotomy (Exhibition Hall/Poster Area) -  Jul 18, 2024 - Abstract #IASP2024IASP_2619;    
    At skull pin insertion, ANIi and ANIm had a higher degree of change with significantly greater response time in the OFA group. This emphasizes that when OFA is used, ANI might be a superior choice as it appears to be more sensitive.
  • ||||||||||  fentanyl citrate / Generic mfg., morphine sulphate / Generic mfg., midazolam hydrochloride / Generic mfg.
    Systematic review of neurodevelopmental impact of pharmacological interventions for pain in preterm (Exhibition Hall/Poster Area) -  Jul 18, 2024 - Abstract #IASP2024IASP_2486;    
    A lot of improvements have been made on managing acute pain with non-pharmacological interventions, with a very low odd of adverse events. Prolonged pain such as mechanical ventilation, necrotising enterocolitis, surgical operations, require pharmacological interventions.
  • ||||||||||  fentanyl citrate / Generic mfg., ropivacaine / Generic mfg.
    Analgesic efficacy of bilateral ultrasound guided erector spinae plane block in a patient undergoing (Exhibition Hall/Poster Area) -  Jul 18, 2024 - Abstract #IASP2024IASP_2361;    
    The patient in group 1 received ESP block with 0.3 ml/kg of 0.5% ropivacaine under ultrasound guidance before anaesthesia induction at T5 spinous level, while patients in group 2 did not receive any block. Use of bilateral ESP block provides effective analgesia promoting early extubation of patients, and also reduces post-operative opioid consumption and its associated side effect with better patient's satisfaction in relieving acute postoperative pain after cardiac surgery.
  • ||||||||||  fentanyl citrate / Generic mfg., morphine sulphate / Generic mfg., hydromorphone hydrochloride / Generic mfg.
    Targeted Drug Delivery for Treatment of Chronic Abdominal Pain in Patient with Chronic Pancreatitis (Exhibition Hall/Poster Area) -  Jul 18, 2024 - Abstract #IASP2024IASP_2201;    
    This study constitutes the largest study investigating efficacy and safety of TDD in patients with chronic pancreatitis. Targeted drug delivery provides improved pain control with significantly lower opioid dose and is an effective treatment in patients who have failed multiple treatment modalities including medications and surgical interventions for treatment of chronic abdominal pain secondary to chronic pancreatitis.
  • ||||||||||  fentanyl citrate / Generic mfg., morphine sulphate / Generic mfg.
    Multi-targeted Ligands for Pain Relief: Analgesic Properties of Dual Opioid/Neurotensin Peptides (Exhibition Hall/Poster Area) -  Jul 18, 2024 - Abstract #IASP2024IASP_2187;    
    Targeted drug delivery provides improved pain control with significantly lower opioid dose and is an effective treatment in patients who have failed multiple treatment modalities including medications and surgical interventions for treatment of chronic abdominal pain secondary to chronic pancreatitis. The gold standard for the management of moderate to severe pain is to target the
  • ||||||||||  ropivacaine / Generic mfg.
    Evaluation of Optimal epidural infusion dose of ropivacaine in the management of post-operative pain (Exhibition Hall/Poster Area) -  Jul 18, 2024 - Abstract #IASP2024IASP_1679;    
    Severe intolerable pain patients were referred to a tertiary military hospital located within 2 kilometers from the center and were managed with opioid therapy Thoracic epidural administration of ropivacaine-fentanyl solution with 50% hourly epidural infusion dose in form of background infusion provides better pain relief as compared to 25% hourly epidural infusion after major abdominal surgery.