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  • ||||||||||  fentanyl citrate / generics, chlorpromazine / generics
    Clinical, Journal:  Risk factors for intensive care unit delirium after cardiac operation (Pubmed Central) -  Jul 26, 2019   
    Among them, the educational level, CPB time, duration of mechanical ventilation, and midazolam are intervention factors. In clinical treatment, not only the risk factors should be identified, but also intervention should be taken to prevent the occurrence of delirium.
  • ||||||||||  fentanyl citrate / generics
    Clinical, Journal, Combination therapy:  Comparison of the Sedation Quality of Etomidate, Propofol, and Midazolam in Combination with Fentanyl During Phacoemulsification Cataract Surgery: A Double-Blind, Randomized, Controlled, Clinical Trial. (Pubmed Central) -  Jul 26, 2019   
    The median recovery time was significantly higher in the midazolam group than the propofol group (P = 0.04); intergroup comparisons indicated that the patients' mean score of satisfaction in the propofol group was significantly higher than that of the etomidate group (P = 0.006). The current study findings indicated that though the quality of sedation during phacoemulsification cataract surgery was acceptable in the three agents and the results had no significantly differences among the groups, and considering other factors including recovery time, hemodynamic evaluation, sedation-related complications, and patients' satisfication scores, it is suggested that propofol was superior to the other two agents.
  • ||||||||||  fentanyl citrate / generics
    Journal:  Nurses' knowledge and practices regarding pain management in newborns. (Pubmed Central) -  Jul 26, 2019   
    The dose of 7.5 mg hyperbaric bupivacaine 0.5% and 25 mcg of fentanyl can be used as a prevention measure against hypotension due to spinal anesthesia cesarean delivery. Nurses considered neonatal pain a real event; however, they do not perform pain assessment or treatment of newborns in a systematized way.It is necessary to implement knowledge translation strategiesin order to improve pain management in newborns.
  • ||||||||||  fentanyl citrate / generics
    Journal:  The US Opioid Epidemic and Its Impact on US General Practice Veterinarians. (Pubmed Central) -  Jul 25, 2019   
    ...The most difficult drugs to obtain were hydromorphone, morphine, injectable fentanyl, and oxymorphone...Conclusions and Clinical Relevance: Veterinarians' ability to provide opioids for their patients has been impacted by the opioid shortage, with a greater impact on full mu opioid agonists as compared to drugs like butorphanol, buprenorphine, and tramadol. The results confirm the important role of opioid analgesics in the delivery of modern veterinary medicine and highlight the importance of medical health professionals being able to access these critical medications.
  • ||||||||||  fentanyl citrate / generics
    Journal:  Intravenous dexmedetomidine augments the oculocardiac reflex. (Pubmed Central) -  Jul 24, 2019   
    Mycophenolic acid and tacrolimus also did not show significant sequestration in the circuit, which was unexpected given their lipophilicity and protein-binding characteristics, but may provide insight into unexplored pharmacokinetics of particular medications in ECMO circuits. Similar to the effect of fentanyl, intravenous fast-push dexmedetomidine augmented the bradycardia associated with extraocular muscle traction.
  • ||||||||||  fentanyl citrate / generics
    Journal:  "Characterization of the antinociceptive effects of intrathecal DALDA peptides following bolus intrathecal delivery". (Pubmed Central) -  Jul 21, 2019   
    ...In separate studies, the effects of approximately equiactive doses of IT DMT DALDA (10 pmol), morphine (30 nmol) and fentanyl (1 nmol) were examined on formalin-induced flinching at different pretreatment intervals (15 min - 24 h)...The asymmetric cross-tolerance between equiactive doses may reflect the relative intrinsic activity of morphine and DMT-DALDA. Implications These results suggest that the DALDA peptides with their potency and duration of action after intrathecal delivery suggest their potential utility for their further development as a spinal therapeutic to manage pain.
  • ||||||||||  fentanyl citrate / generics
    Journal:  Free trade and opioid overdose death in the United States. (Pubmed Central) -  Jul 18, 2019   
    We find that the loss of 1000 trade-related jobs was associated with a 2.7 percent increase in opioid-related deaths. When fentanyl was present in the heroin supply, the same number of job losses was associated with a 11.3 percent increase in opioid-related deaths.
  • ||||||||||  fentanyl citrate / generics
    Journal:  Effects of continuous positive airway pressure on respiratory function in sedated foals. (Pubmed Central) -  Jul 17, 2019   
    Findings of the study suggest that CPAP might represent a method for improved respiratory support compared to O insufflation due to increased respiratory efficiency. Care must be taken in extrapolation of these findings from foals with pharmacologically induced respiratory compromise to foals with clinical respiratory disease, and further investigation is required to better characterize the cause and impact of marginal hypercapnia observed in these studies.
  • ||||||||||  fentanyl citrate / generics
    Review, Journal:  Novel synthetic opioids - toxicological aspects and analysis. (Pubmed Central) -  Jul 16, 2019   
    ...Clinicians dealing with fentanyl intoxication cases should consider that it could, in fact, be a fentanyl analogue...To address this public health problem, better international collaboration, effective legislation, effective investigation, control of suspicious "research chemicals" online forums and continuous community alertness are required. This article aims to review diverse reported fatalities associated with new synthetic opioids describing them in terms of pharmacology, metabolism, posology, available forms, as well as their toxic effects, highlighting the sample procedures and analytical techniques available for their detection and quantification in biological matrices.
  • ||||||||||  tramadol / Fortress
    Journal:  Potential intravenous drug interactions in intensive care. (Pubmed Central) -  Jul 13, 2019   
    This article aims to review diverse reported fatalities associated with new synthetic opioids describing them in terms of pharmacology, metabolism, posology, available forms, as well as their toxic effects, highlighting the sample procedures and analytical techniques available for their detection and quantification in biological matrices. A previous mapping of prescriptions enables the characterization of the drug therapy, contributing to prevent potential drug interactions and their clinical consequences.