| Dapivirine Vaginal Ring (dapivirine) / International Partnership for Microbicides, J&J |
NCT02010593: Safety and Pharmacokinetics of Dapivirine Vaginal Ring in Post-menopausal Women |
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| Completed | 2a | 96 | US | Dapivirine Vaginal Ring, TMC-120, Placebo Vaginal Ring | International Partnership for Microbicides, Inc., National Institute of Allergy and Infectious Diseases (NIAID) | Human Immunodeficiency Virus | 04/15 | 04/15 | | |
NCT02028338: Study of Dapivirine Vaginal Ring (VR) in Adolescents |
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| Completed | 2a | 96 | US | placebo ring, dapivirine ring | International Partnership for Microbicides, Inc., Microbicide Trials Network, National Institutes of Health (NIH) | Human Immunodeficiency Virus | 07/16 | 06/18 | | |
NCT03074786: Reversing the Epidemic in Africa With Choices in HIV Prevention (REACH) |
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| Withdrawn | 2a | 0 | RoW | Dapivirine, Vaginal Ring, Truvada, Emtricitabine/tenofovir | International Partnership for Microbicides, Inc., Gilead Sciences | HIV-1-infection | 12/18 | 12/20 | | |
REACH, NCT03593655: Evaluating the Safety of and Adherence to a Vaginal Matrix Ring Containing Dapivirine and Oral Emtricitabine/Tenofovir Disoproxil Fumarate in an Adolescent and Young Adult Female Population |
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| Completed | 2a | 247 | RoW | Dapivirine vaginal ring, FTC/TDF, Emtricitabine/Tenofovir Disoproxil Fumarate; Truvada | National Institute of Allergy and Infectious Diseases (NIAID) | HIV Infections | 09/21 | 09/21 | | |
NCT01071174: A Safety Study of Dapivirine Vaginal Ring in Africa |
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| Completed | 1/2 | 280 | RoW | Dapivirine, Placebo | International Partnership for Microbicides, Inc. | HIV Infections | 05/11 | 07/11 | | |
NCT05041699: PK, Safety Study of 90-Day Use of Vaginal Rings Containing Dapivirine and Levonorgestrel |
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| Recruiting | 1/2 | 40 | US | IPM Ring-105, IPM Ring-106 | International Partnership for Microbicides, Inc., Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH) | Pharmacokinetics, Safety Issues, Bleeding | 08/24 | 12/24 | | |
