Dapivirine Vaginal Ring (dapivirine) / International Partnership for Microbicides, J&J |
NCT03965923: Randomized, Open Label Safety Trial of Dapivirine Vaginal Ring and Oral TRUVADA® Use in Pregnancy |
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| Active, not recruiting | 3b | 859 | RoW | Dapivirine (DPV) Vaginal Ring (VR), Truvada Tablet, Emtricitabine/Tenofovir Disoproxil Fumarate, FTC/TDF | National Institute of Allergy and Infectious Diseases (NIAID) | HIV Infections | 06/24 | 06/24 | | |
LAPIS, NCT06250504: Long-Acting HIV Pre-Exposure Prophylaxis Integrated With Sexual and Reproductive Health - cRCT |
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| Recruiting | 3 | 2000 | RoW | APRETUDE (cabotegravir) 600 mg\3 mL, DAPIRING (Dapivirine) 25mg Vaginal Ring, tenofovir disoproxil and emtricitabine, Tenofovir Disoproxil, Lamuvidine and Dolutegravir | Africa Health Research Institute | HIV Infections | 07/25 | 03/26 | | |
NCT05041699: PK, Safety Study of 90-Day Use of Vaginal Rings Containing Dapivirine and Levonorgestrel |
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| Active, not recruiting | 1/2 | 40 | US | IPM Ring-105, IPM Ring-106 | International Partnership for Microbicides, Inc., Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH) | Pharmacokinetics, Safety Issues, Bleeding | 10/24 | 12/24 | | |
NCT02658227: Pharmacokinetic Study of the Dapivirine Vaginal Ring in Lactating Women |
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| Recruiting | 1 | 16 | US | Dapivirine, Dapivirine Vaginal Ring | International Partnership for Microbicides, Inc. | HIV Infections | 08/17 | 08/17 | | |
NCT05416021: Relative Bioavailability Trial of Dapivirine Ring-004 and Ring-008 |
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| Completed | 1 | 124 | RoW | dapivirine | International Partnership for Microbicides, Inc. | HIV Infections | 04/24 | 07/24 | | |