| amitriptyline / Generic mfg. |
ACTRN12623001158651: The influence of amitriptyline on human thermoregulation in young healthy adults |
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| Not yet recruiting | 4 | 12 | | | The University of Sydney, The University of Sydney (Discretionary Research Account held by Dr. Ollie Jay) | Heat related thermal strain, Heat related cardiovascular strain, Heat related changes in thermal perceptions (i.e., comfort and sensation) | | | | |
ACTRN12615000413527: Optimizing post operative outcomes in Total Knee Arthroplasty (TKR) through improved pain and fatigue management: a randomized placebo controlled trial. |
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| Recruiting | 4 | 104 | | | ORIQL , Orthopaedic Research Institute of Queensland (ORIQL) | Knee Osteoarthritis, Post Operative Management of Total Knee Arthroplasty | | | | |
| Completed | 4 | 125 | US | Amitriptyline | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Amputation, Traumatic, Pain, Postoperative Pain | 07/01 | | | |
NCT00000428: Combining N-of-1 Trials to Assess Fibromyalgia Treatments |
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| Completed | 4 | 58 | US | Amitriptyline, Elavil, Amitriptyline plus Fluoxitine, elavil plus prozac | Tufts Medical Center, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | Fibromyalgia | 03/04 | 03/04 | | |
NCT00189059: Effects of Amitriptyline for the Treatment of Pain on Driving Performance and Cognition. |
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| Terminated | 4 | 24 | Europe | amitriptyline | UMC Utrecht, Utrecht University | Chronic Neuropathic Pain | | 05/05 | | |
NCT00266643: Tolerability of Switching to Duloxetine for the Management of Diabetic Nerve Pain |
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| Completed | 4 | 205 | US | duloxetine hydrochloride | Eli Lilly and Company | Diabetic Neuropathy, Painful | | 04/07 | | |
| Completed | 4 | 100 | US | Amitriptyline | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Spinal Cord Injuries, Pain | 05/07 | 05/07 | | |
NCT00564525: Study of Medication for Functional Abdominal Pain in Children |
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| Completed | 4 | 95 | US | Amitriptyline, Other names include: Elavil, Trepiline and Laroxyl., Placebo | Ann & Robert H Lurie Children's Hospital of Chicago, American College of Gastroenterology | Functional Gastrointestinal Disorders | | 06/07 | | |
2006-005533-38: 'Studies in patients with chronic cough; montelukast and amitriptyline studies’. |
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| | 4 | 182 | Europe | | there is no sponsor. | Chronic cough ( cough lasting > 8 weeks). | | | | |
| Completed | 4 | 90 | Europe | amitriptyline, Tryptizol, quetiapine, Seroquel XR | Universidad de Granada, AstraZeneca, Hospital Clinico Universitario San Cecilio | Fibromyalgia | 03/10 | 10/10 | | |
ChiCTR-TTRCC-12001967: The effects of low dose amitriptyline on gastrointestinal function and its side effects in healthy volunteers: A prospective, randomized,double-blind ,placebo-controlled cross-over trial |
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| Completed | 4 | 28 | | Amitriptyline at 12.5mg p.o. three times each day for continous 7 days,followed by 14-day washout interval,then with placebo at 12.5mg p.o. three times each day for continuous 7 day ;Placebo at 12.5mg p.o. three times each day for continuous 7 days, followed by 14-day washout interval,then with Amitriptyline at 12.5mg p.o. three times each day for continous 7 days | Guangzhou First Municipal People's Hospital, Guangzhou Nan Sha Center Hospital Affiliated to Guangzhou Medical College; Guangzhou First Municipal People's Hospital, Guangzhou Nan Sha Center Hospital Affiliated to Guangzhou Medical College, Self-funding | Healthy volunteers | | | | |
ChiCTR-TRC-12001968: Epidemiology survey and the effects of low-dose Amitriptyline on Intractable Functional Dyspepsia: A prospective, randomized, controlled study |
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| Completed | 4 | 60 | | to be treated with both routine drugs and amitriptyline (12.5-37.5mg) during 4 weeks. ;To be treated with routine drugs for 4 weeks | Guangzhou First Municipal People's Hospital, Guangzhou Nan Sha Center Hospital; Guangzhou Nan Sha Center Hospital, Self-funding | Intractable functional dyspepsia | | | | |
ChiCTR-TRC-12001969: Incidence of refractory irritable bowel syndrome and the effects of low dose amitriptyline in the patients: A prospective, randomized-controlled trial |
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| Completed | 4 | 50 | | Conventional therapy plus Amitriptyline 12.5-37.5mg/day,p.o. for 4 weeks ;Conventional therapy for 4 weeks | Guangzhou First Municipal People's Hospital, Guangzhou Nan Sha Center Hospital Affiliated to Guangzhou Medical College; Guangzhou First Municipal People's Hospital, Guangzhou Nan Sha Center Hospital Affiliated to Guangzhou Medical College, Self-funding | Refractory irritable bowel syndrome | | | | |
NCT00862095: Medical Therapies for Chronic Post-Traumatic Headaches |
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| Terminated | 4 | 64 | US | Placebo, Propranolol, Inderal, Amitriptyline, Elavil, Topiramate, Topamax | Madigan Army Medical Center, U.S. Army Medical Research and Development Command | Headache | 04/13 | 04/13 | | |
| Completed | 4 | 212 | RoW | Amitryptiline, Tryptizol, Laroxyl, Placebo, No brand name | St Joseph University, Beirut, Lebanon | Neck Pain | 06/14 | 06/14 | | |
NCT01869907: Effect of Minocycline on Pain Caused by Nerve Damage |
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| Completed | 4 | 60 | Europe | Minocycline, placebo, Amitriptyline | Ziekenhuis Oost-Limburg | Neuropathic Pain Caused by Lumbar Radicular Pain | 08/14 | 08/14 | | |
ChiCTR-TRC-14005097: Effects of Antidepressants paroxetine and amitriptyline in refractory globus sensation Patients: A prospective, randomized-controlled trial |
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| Recruiting | 4 | 90 | | Paroxetine 20mg/day, p.o. for 4 weeks ;amitriptyline 25mg/qn,p.o. for 4 weeks ;Conventional therapy for 4 weeks | Guangzhou First Municipal People's Hospital, Guangzhou Nan Sha Center Hospital Affiliated to Guangzhou Medical University; Level of the institution：, Self-funding | refractory globus sensation | | | | |
| Unknown status | 4 | 80 | Europe | Paroxetine, Sertraline, Citalopram, Venlafaxine, Amitriptyline, Escitalopram, Amitriptylinoxide, Nortriptyline, Trimipramine | HolsboerMaschmeyer NeuroChemie GmbH, Max-Planck-Institute of Psychiatry | Major Depression | 12/14 | 12/14 | | |
JFR, NCT02593734: Integrating Psychotropic Medication Into the Care of People With Mental Disorders in a Prayer Camp in Ghana |
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| Completed | 4 | 139 | RoW | olanzapine, Zyprexa, risperidone, Risperdal, amitryptaline, Elavil, fluoxetine, Prozac | University of Ghana Medical School | Schizophrenia, Mood Disorders,, Anxiety Disorder | 07/15 | 07/15 | | |
NCT02190526: Effects of Mesalamine and Amitriptyline on Irritable Bowel Syndrome |
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| Withdrawn | 4 | 0 | RoW | Mesalazine(asacol 800 mg), Amitriptyline, placebo like asacol, placebo like amitriptyline | Tehran University of Medical Sciences, Tillotts Pharma AG | Diarrhea- Predominant Irritable Bowel Syndrome, Quality of Life | 12/15 | 12/15 | | |
ChiCTR-IPR-15006796: The effects of low dose amitriptyline on upper esophageal sphincter (UES) resting pressure in healthy volunteers: A prospective, randomized,double-blind ,placebo-controlled trial |
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| Not yet recruiting | 4 | 40 | | amitriptyline 25mg/qn,p.o. for 7 days ;placebo 25mg/qn,p.o. for 7 days | Guangzhou First Municipal People's Hospital, Guangzhou Nansha Central Hospital Affiliated to Guangzhou Medical University; Guangzhou First Municipal People's Hospital, Guangzhou Nansha Central Hospital Affiliated to Guangzhou Medical University, self-funded | Healthy volunteers | | | | |
| Ongoing | 4 | 50 | Europe | Paroxetine, Amitriptyline, Clomipramine, Imipramine, Nortriptyline, escitalopram, Citalopram, Fluoxetine, Fluvoxamine, Sertraline, Duloxetine, venlafaxine, EU/1/04/296/002, Seroxat, Tryptizol, Anafranil, Imipramine, Nortrilen, Lexapro, Cipramil, prozac, Fevarin, Zoloft, Cymbalta, Efexor, Seroxat, Tryptizol, Anafranil, Imipramine, Nortrilen, Lexapro, Cipramil, prozac, Fevarin, Zoloft, Cymbalta, Efexor | Isala Klinieken | Pregnant women with psychiatric morbidity and an strong indication for using antidepressants | | | | |
NCT02339662: Prospective, Cross Over Gabapentin vs Amitriptyline Study on Patients Suffering From Masticatory Muscle Pain |
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| Unknown status | 4 | 50 | RoW | Gabapentin, Amitriptyline, alterolet | Doron Aframian | Myofacial Pain | 01/16 | 01/17 | | |
ChiCTR-IPR-15006797: The classification of upper esophageal sphincter (UES) resting pressure and the efficacy of antidepressants for globus pharyngeus |
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| Not yet recruiting | 4 | 60 | | Paroxetine 20mg/qn,p.o. for 6 weeks ;amitriptyline 25mg/qn,p.o. for 6 weeks ;Conventional therapy for 6 weeks | Guangzhou First Municipal People's Hospital, Guangzhou Nansha Central Hospital Affiliated to Guangzhou Medical University; Guangzhou First Municipal People's Hospital, Guangzhou Nansha Central Hospital Affiliated to Guangzhou Medical University, self-funded | globus pharyngeus | | | | |
2016-003325-41: PREemptive Pharmacogenomic testing for Preventing Adverse drug REactions (PREPARE) |
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| Ongoing | 4 | 450 | Europe | Syrup, Tablet, Capsule, hard, Powder for injection, Capsule, Solution for injection, Concentrate for solution for infusion, Powder for solution for infusion, Codeine, Acenocoumarol, Amitriptyline, Aripiprazole, Atomoxetine, Atorvastatine, Azathioprine, Capecitabine, Carbamazepine, Citalopram, Clomipramine, Clopidogrel, Clozapine, Efavirenz, Escitalopram, Flecainide, Flucloxacillin, Fluorouracil, Haloperidol, Irinotecan, Mercaptopurine, Metoprolol, Oxycodone, Paroxetine, Phenprocoumon, Phenytoin, ORAP 1 mg Tabletten, Propafenone, Sertraline, Simvastatin, Tacrolimus, Tamoxifen, Tegafur, Tioguanine, Tramadol, Venlafaxine, Voriconazole, Zuclopenthixol, Ethinylestradiol, ORAP 4 mg Tabletten | Leiden University Medical Center, Leiden University Medical Center | Adverse drug reactions, Side-effects, Not possible to specify | | | | |
NCT02256956: Genetic Determinants of Amitriptyline Efficiency for Pain Treatment - Part II |
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| Completed | 4 | 48 | Europe | Amitriptyline, Tryptizol, Tolterodine | University Hospital Inselspital, Berne, University of Washington, Aalborg University, Ludwig-Maximilians - University of Munich | Chronic Pain | 05/18 | 01/19 | | |
NCT02256943: Genetic Determinants of Amitriptyline Efficiency for Pain Treatment |
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| Completed | 4 | 48 | Europe | Amitriptyline, Tryptizol, Tolterodine | University Hospital Inselspital, Berne, University of Washington, Ludwig-Maximilians - University of Munich, Aalborg University | Chronic Pain | 05/18 | 01/19 | | |
ECCP, NCT04523935: Excessive Crying in Children With Cerebral Palsy and Communication Deficits |
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| Completed | 4 | 131 | NA | Placebo, Fruit sugar, levulose., Baclofen, Diazepam, Clonazepam, Trihexyphenidyl, Tetrabenazine, Gabapentin, Topiramate, Lamotrigine, Amitriptyline., Baclofen(Liofen®),Diazepam,(Valium®),Clonazepam,(Klonopin®),Trihexyphenidyl(Artane®),Tetrabenazine(Xenazine®),Gabapentin(Neurontin®),Topiramate(Topamax®),Lamotrigine(Lamictal®),Amitriptyline(Elavil®) | Sathbhavana Brain Clinic | Cerebral Palsy, Excessive Crying, Pain | 08/20 | 08/20 | | |
NCT05759845: Topiramate, Amitriptyline Monotherapy and Combination Therapy in Migraine Prophylaxis |
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| Enrolling by invitation | 4 | 150 | RoW | Topiramate 25Mg Tab, Amitriptyline 25 Mg Oral Tablet, topiramate 25mg plus amitriptyline 25mg | Dr. Reaz Mahmud | Migraine | 02/23 | 05/23 | | |
NCT05867550: To Compare the Efficacy of Drugs in Combination for Treating Irritable Bowel Syndrome Associated With Diarrhea |
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| Completed | 4 | 162 | RoW | Rifaximin 550 MG, Rifaxa 550MG, Nimixa 550 MG, Xifaxa 550MG, Zerifax 550MG, Nixaf 550 MG, Mebeverine 135 MG, Colofac 135 MG, Spasler Neo 135 MG, Mebever 135 MG, Psyllium Husk, Ispaghol, Amitriptyline Hydrochloride 25 MG, Tryptanol 25 MG | Bahria University | Irritable Bowel Syndrome With Diarrhea | 03/23 | 06/23 | | |
ChiCTR2100054831: Clinical efficacy and safety of duloxetine hydrochloride and amitriptyline combined with pregabalin in patients with herpes zoster neuralgia |
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| Recruiting | 4 | 80 | | Duloxetine combined with pregabalin ;Amitriptyline combined with pregabalin | Nanjing Drum Tower Hospital, School of Medicine, Nanjing University; Nanjing Drum Tower Hospital, School of Medicine, Nanjing University, Nanjing Drum Tower Hospital, School of Medicine, Nanjing University | Herpes zoster neuralgia | | | | |
IC3D, NCT04777006: Integrating a Stepped Care Model of Screening and Treatment for Depression Into Malawi's National HIV Care Delivery Platform |
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| Active, not recruiting | 4 | 487 | RoW | Problem Management Plus, PM+, Antidepressant Therapy, Fluoxetine, Amitriptyline | RAND, National Institute of Mental Health (NIMH), Partners in Health, Brigham and Women's Hospital, Malawi Ministry of Health, Blantyre College of Medicine, University of Birmingham | Depressive Disorder | 11/23 | 06/25 | | |
