| amitriptyline / Generic mfg. |
ACTRN12623001158651: The influence of amitriptyline on human thermoregulation in young healthy adults |
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| Not yet recruiting | 4 | 12 | | | The University of Sydney, The University of Sydney (Discretionary Research Account held by Dr. Ollie Jay) | Heat related thermal strain, Heat related cardiovascular strain, Heat related changes in thermal perceptions (i.e., comfort and sensation) | | | | |
ACTRN12615000413527: Optimizing post operative outcomes in Total Knee Arthroplasty (TKR) through improved pain and fatigue management: a randomized placebo controlled trial. |
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| Recruiting | 4 | 104 | | | ORIQL , Orthopaedic Research Institute of Queensland (ORIQL) | Knee Osteoarthritis, Post Operative Management of Total Knee Arthroplasty | | | | |
ChiCTR-TTRCC-12001967: The effects of low dose amitriptyline on gastrointestinal function and its side effects in healthy volunteers: A prospective, randomized,double-blind ,placebo-controlled cross-over trial |
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| Completed | 4 | 28 | | Amitriptyline at 12.5mg p.o. three times each day for continous 7 days,followed by 14-day washout interval,then with placebo at 12.5mg p.o. three times each day for continuous 7 day ;Placebo at 12.5mg p.o. three times each day for continuous 7 days, followed by 14-day washout interval,then with Amitriptyline at 12.5mg p.o. three times each day for continous 7 days | Guangzhou First Municipal People's Hospital, Guangzhou Nan Sha Center Hospital Affiliated to Guangzhou Medical College; Guangzhou First Municipal People's Hospital, Guangzhou Nan Sha Center Hospital Affiliated to Guangzhou Medical College, Self-funding | Healthy volunteers | | | | |
ChiCTR-TRC-12001968: Epidemiology survey and the effects of low-dose Amitriptyline on Intractable Functional Dyspepsia: A prospective, randomized, controlled study |
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| Completed | 4 | 60 | | to be treated with both routine drugs and amitriptyline (12.5-37.5mg) during 4 weeks. ;To be treated with routine drugs for 4 weeks | Guangzhou First Municipal People's Hospital, Guangzhou Nan Sha Center Hospital; Guangzhou Nan Sha Center Hospital, Self-funding | Intractable functional dyspepsia | | | | |
ChiCTR-TRC-12001969: Incidence of refractory irritable bowel syndrome and the effects of low dose amitriptyline in the patients: A prospective, randomized-controlled trial |
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| Completed | 4 | 50 | | Conventional therapy plus Amitriptyline 12.5-37.5mg/day,p.o. for 4 weeks ;Conventional therapy for 4 weeks | Guangzhou First Municipal People's Hospital, Guangzhou Nan Sha Center Hospital Affiliated to Guangzhou Medical College; Guangzhou First Municipal People's Hospital, Guangzhou Nan Sha Center Hospital Affiliated to Guangzhou Medical College, Self-funding | Refractory irritable bowel syndrome | | | | |
ChiCTR-TRC-14005097: Effects of Antidepressants paroxetine and amitriptyline in refractory globus sensation Patients: A prospective, randomized-controlled trial |
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| Recruiting | 4 | 90 | | Paroxetine 20mg/day, p.o. for 4 weeks ;amitriptyline 25mg/qn,p.o. for 4 weeks ;Conventional therapy for 4 weeks | Guangzhou First Municipal People's Hospital, Guangzhou Nan Sha Center Hospital Affiliated to Guangzhou Medical University; Level of the institution：, Self-funding | refractory globus sensation | | | | |
ChiCTR-IPR-15006796: The effects of low dose amitriptyline on upper esophageal sphincter (UES) resting pressure in healthy volunteers: A prospective, randomized,double-blind ,placebo-controlled trial |
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| Not yet recruiting | 4 | 40 | | amitriptyline 25mg/qn,p.o. for 7 days ;placebo 25mg/qn,p.o. for 7 days | Guangzhou First Municipal People's Hospital, Guangzhou Nansha Central Hospital Affiliated to Guangzhou Medical University; Guangzhou First Municipal People's Hospital, Guangzhou Nansha Central Hospital Affiliated to Guangzhou Medical University, self-funded | Healthy volunteers | | | | |
| Ongoing | 4 | 50 | Europe | Paroxetine, Amitriptyline, Clomipramine, Imipramine, Nortriptyline, escitalopram, Citalopram, Fluoxetine, Fluvoxamine, Sertraline, Duloxetine, venlafaxine, EU/1/04/296/002, Seroxat, Tryptizol, Anafranil, Imipramine, Nortrilen, Lexapro, Cipramil, prozac, Fevarin, Zoloft, Cymbalta, Efexor, Seroxat, Tryptizol, Anafranil, Imipramine, Nortrilen, Lexapro, Cipramil, prozac, Fevarin, Zoloft, Cymbalta, Efexor | Isala Klinieken | Pregnant women with psychiatric morbidity and an strong indication for using antidepressants | | | | |
ChiCTR-IPR-15006797: The classification of upper esophageal sphincter (UES) resting pressure and the efficacy of antidepressants for globus pharyngeus |
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| Not yet recruiting | 4 | 60 | | Paroxetine 20mg/qn,p.o. for 6 weeks ;amitriptyline 25mg/qn,p.o. for 6 weeks ;Conventional therapy for 6 weeks | Guangzhou First Municipal People's Hospital, Guangzhou Nansha Central Hospital Affiliated to Guangzhou Medical University; Guangzhou First Municipal People's Hospital, Guangzhou Nansha Central Hospital Affiliated to Guangzhou Medical University, self-funded | globus pharyngeus | | | | |
2016-003325-41: PREemptive Pharmacogenomic testing for Preventing Adverse drug REactions (PREPARE) |
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| Ongoing | 4 | 450 | Europe | Syrup, Tablet, Capsule, hard, Powder for injection, Capsule, Solution for injection, Concentrate for solution for infusion, Powder for solution for infusion, Codeine, Acenocoumarol, Amitriptyline, Aripiprazole, Atomoxetine, Atorvastatine, Azathioprine, Capecitabine, Carbamazepine, Citalopram, Clomipramine, Clopidogrel, Clozapine, Efavirenz, Escitalopram, Flecainide, Flucloxacillin, Fluorouracil, Haloperidol, Irinotecan, Mercaptopurine, Metoprolol, Oxycodone, Paroxetine, Phenprocoumon, Phenytoin, ORAP 1 mg Tabletten, Propafenone, Sertraline, Simvastatin, Tacrolimus, Tamoxifen, Tegafur, Tioguanine, Tramadol, Venlafaxine, Voriconazole, Zuclopenthixol, Ethinylestradiol, ORAP 4 mg Tabletten | Leiden University Medical Center, Leiden University Medical Center | Adverse drug reactions, Side-effects, Not possible to specify | | | | |
NCT05759845: Topiramate, Amitriptyline Monotherapy and Combination Therapy in Migraine Prophylaxis |
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| Enrolling by invitation | 4 | 150 | RoW | Topiramate 25Mg Tab, Amitriptyline 25 Mg Oral Tablet, topiramate 25mg plus amitriptyline 25mg | Dr. Reaz Mahmud | Migraine | 02/23 | 05/23 | | |
NCT05867550: To Compare the Efficacy of Drugs in Combination for Treating Irritable Bowel Syndrome Associated With Diarrhea |
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| Completed | 4 | 162 | RoW | Rifaximin 550 MG, Rifaxa 550MG, Nimixa 550 MG, Xifaxa 550MG, Zerifax 550MG, Nixaf 550 MG, Mebeverine 135 MG, Colofac 135 MG, Spasler Neo 135 MG, Mebever 135 MG, Psyllium Husk, Ispaghol, Amitriptyline Hydrochloride 25 MG, Tryptanol 25 MG | Bahria University | Irritable Bowel Syndrome With Diarrhea | 03/23 | 06/23 | | |
ChiCTR2100054831: Clinical efficacy and safety of duloxetine hydrochloride and amitriptyline combined with pregabalin in patients with herpes zoster neuralgia |
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| Recruiting | 4 | 80 | | Duloxetine combined with pregabalin ;Amitriptyline combined with pregabalin | Nanjing Drum Tower Hospital, School of Medicine, Nanjing University; Nanjing Drum Tower Hospital, School of Medicine, Nanjing University, Nanjing Drum Tower Hospital, School of Medicine, Nanjing University | Herpes zoster neuralgia | | | | |
IC3D, NCT04777006: Integrating a Stepped Care Model of Screening and Treatment for Depression Into Malawi's National HIV Care Delivery Platform |
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| Active, not recruiting | 4 | 487 | RoW | Problem Management Plus, PM+, Antidepressant Therapy, Fluoxetine, Amitriptyline | RAND, National Institute of Mental Health (NIMH), Partners in Health, Brigham and Women's Hospital, Malawi Ministry of Health, Blantyre College of Medicine, University of Birmingham | Depressive Disorder | 11/23 | 06/25 | | |
ACTRN12619000158167: Combined speech pathology and amitriptyline treatment for vocal cord dysfunction. |
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| Recruiting | 3 | 50 | | | LaTrobe University, The Alfred | Vocal Cord Dysfunction | | | | |
ACTRN12612000655842: Is amitriptyline cream effective in the management of vestibulodynia - a condition which refers to pain at the opening of the vagina? |
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| Recruiting | 3 | 50 | | | Dr Ross Pagano, The Royal Womens Hospital | Vestibulodynia | | | | |
2014-003581-25: Therapy of lungs of CF-patients with Amitriptyline - a randomised, double-blind, placebo-controlled cohort trial Anti-inflammatorische pulmonale Therapie von CF-Patienten mittels Amitriptylin und Placebo - Placebokontrollierte, prospektive, randomisierte, doppel-blinde Kohorten-Studie |
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| Ongoing | 3 | 102 | Europe | Amitriptyline, Capsule, Amitriptylin-CT | University Hospital Tuebingen, BMBF | Amitriptyline reduces ceramide concentrations in bronchial epithelial cells and reduces cell death and reduces the deposition of DNA on the respiratory epithelium. This reduction promotes the elimination of P. aeruginosa bacteria from the lung. As a result, treatment normalizes inflammation in CF lungs. Amitriptyline thus reduces systemic and local inflammation. Because of these effects, amitriptyline increases lung function in CF patients., Amitriptyline reduces cell death in epithelial cells of the lung, reduces inflammation and increases lung function., Diseases [C] - Respiratory Tract Diseases [C08] | | | | |
2016-003146-89: Optimal pathway for treating neuropathic pain in diabetes mellitus. |
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| Ongoing | 3 | 392 | Europe | Amitriptyline 25mg, Duloxetine, Pregabalin, Capsule, Gastro-resistant capsule, hard, , Amitriptyline 25mg, Duloxetine, Pregabalin 75mg | Sheffield Teaching Hospitals NHS Foundation Trust | Diabetic peripheral neuropathic pain., Painful nerve damage as a result of diabetes., Diseases [C] - Nervous System Diseases [C10] | | | | |
2017-003766-27: The DREAMING study: Efficacy of low dose amitriptyline and mirtazapine for insomnia disorder |
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| Ongoing | 3 | 156 | Europe | amitriptyline, mirtazapine, Film-coated tablet, amitriptyline, mirtazapine | VU University Medical Centre, ZonMw | Insonnia disorder, Sleeping disorder, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2019-001520-35: Treating Insomnia with Medical comorbidity: Low dose Amitriptyline vs cognitive behavioral therapy Een lage dosering amitriptyline en cognitieve gedragstherapie bij langdurige slapeloosheid voor patiënten met een medische aandoening |
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| Ongoing | 3 | 190 | Europe | amitriptyline, Tablet, AMITRIPTYLINE HCl 10 – 25 MG TEVA | Hospital Gelderse Vallei, Amsterdam Univesity Medical Centre | Insomniadisorder Insomniastoornis, Insomnia, sleeplesness Chronische slapeloosheid, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2019-000324-17: Amitriptyline at Low-dose and Titrated for Irritable Bowel Syndrome as Second-line Treatment (The ATLANTIS study): A Double-blind Placebo-controlled Trial |
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| Ongoing | 3 | 518 | Europe | Amitriptyline HCl 10mg Teva film-coated tablets, Film-coated tablet, Amitriptyline HCl 10mg Teva film-coated tablets | University of Leeds, NIHR - Health Technology Assessment (HTA) Programme | Irritable Bowel Syndrome (IBS), Irritable Bowel Syndrome (IBS), Diseases [C] - Digestive System Diseases [C06] | | | | |
| Active, not recruiting | 3 | 102 | RoW | Amitriptyline, Placebo oral capsule, Tramadol | University of Sao Paulo, Cristália Produtos Químicos Farmacêuticos Ltda. | Pain, Neuropathic, Leprosy, Leprosy Neuropathy, Amitriptyline | 05/21 | 08/22 | | |
NCT05658874: A Multidisciplinary, Multimodal Bundled Care Approach to Chronic Pelvic Pain |
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| Recruiting | 3 | 80 | US | Multimodal Bundle Drugs, Overactive Bladder Medication( Trospium/Oxybutynin/Detrol vs. Mirabegron), Operative Cystoscopy, Behavioral health consultation/therapy, Pelvic floor physical therapy, Usual Urogynecologic care, Bladder Instillation, Vaginal estrogen, Methenamine, Amitriptyline/Gabapentin | Jocelyn Fitzgerald | Interstitial Cystitis | 01/25 | 01/25 | | |
NCT04725383: Amitriptyline for Repetitive Behaviors in Autism Spectrum Disorders |
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| Recruiting | 3 | 30 | US | amitriptyline, Elavil | University of Missouri, Kansas City | Autism Spectrum Disorder, Repetitive Compulsive Behavior | 06/25 | 12/25 | | |
2019-003220-21: Management of diarrhoea in ulcerative colitis: multi-arm multi stage trial of low FODMAP diet, amitriptyline, ondansetron, or loperamide: MODULATE. |
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| Not yet recruiting | 2/3 | 491 | Europe | Amitriptyline, Ondansetron, Loperamide, Film-coated tablet, , Amitriptyline | University of Leeds, NIHR - Health Technology Assessment (HTA) Programme | Diarrhoea in patients with stable ulcerative colitis., Diarrhoea in patients with stable ulcerative colitis ., Diseases [C] - Digestive System Diseases [C06] | | | | |
NCT04777838: Myofascial Pain Patients' Response to the Administration of Low Doses of Amitriptyline and Citalopram Compared With the Use of Bite Splint |
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| Not yet recruiting | 2/3 | 80 | Europe | Citalopram 10 MG, Amitriptyline, Bite Splint | University of Coimbra, Instituto de Investigación Biomédica de Salamanca | Muscle Type Temporomandibular Disorders, Myofascial Pain of the Masticatory Muscles | 05/21 | 05/21 | | |
NCT04689958: The Benefits of Vitamin D 5000 IU as Add on Therapy in the Management of Painful Diabetic Neuropathy Patient |
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| Recruiting | 2/3 | 60 | RoW | Standard therapy, Vitamin D 5,000IU Oral Tablet | Duta Wacana Christian University, PT SOHO Global Health Tbk | Painful Diabetic Neuropathy | 11/21 | 11/21 | | |
SOHOBION, NCT04689971: The Benefits of Vitamin B Combination as Add on Therapy in the Management of Painful Diabetic Neuropathy Patient |
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| Recruiting | 2/3 | 60 | RoW | Standard therapy, Vitamin B combination, Vitamin B complex | Duta Wacana Christian University, PT SOHO Global Health Tbk | Painful Diabetic Neuropathy | 11/21 | 11/21 | | |
NCT04689984: The Benefits of Astaxanthin as Add on Therapy in the Management of Painful Diabetic Neuropathy Patient |
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| Recruiting | 2/3 | 60 | RoW | Standard therapy, Astaxanthin | Duta Wacana Christian University, PT SOHO Global Health Tbk | Painful Diabetic Neuropathy | 11/21 | 11/21 | | |
2006-002259-33: Protocol for a Phase II-studyAnti-inflammatory pulmonal therapy of CF-patients with Amitriptyline and Placebo - a randomised, double-blinded, placebo-controlled, cross over study - |
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| Ongoing | 2 | 18 | Europe | Amitriptyline, Amitriptylin-ct Tabletten Wirkstoffstärke 75 mg, Amitriptylin-ct Tabletten Wirkstoffstärke 25 mg, Amitriptylin-ct Tabletten Wirkstoffstärke 75 mg, Amitriptylin-ct Tabletten Wirkstoffstärke 25 mg | Paediatrisches Sekretariat fuer Klinische Studien | CF-patients develop a chronic pulmonary infection with Pseudomonas aeruginosa (P. aeruginosa). At present it is unknown why CF-patients are highly sensitive to P. aeruginosa infections and, most important, no curative treatment for cystic fibrosis is available. This Study should provide a novel anti-inflammatory treatment for cystic fibrosis, which reduces pulmonary complications, progression of the disease and may possibly increase the life-expectance of the patients. | | | | |
2006-005555-15: increased efficacy of lidocaine when amitriptyline is added for local anaesthesia |
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| Ongoing | 2 | 50 | Europe | Xylanaest, Redomex, Xylanest, Redomex, Xylanest, Redomex | Univ.-Prof. Dr. Doris Balogh | The objective of the present study is to investigate whether a combination of ultra-low-dose amitriptyline with the conventional local anesthetic lidocaine enhances the anesthetic effect of the latter via pharmacologic synergy. | | | | |
2020-003965-21: Phase II Randomized Controlled Study Aiming to Evaluate the Interest of Qutenza in Patients With ORL Cancer in Remission and With Sequellae Neuropathic Pain. Phase II randomisée comparative visant à évaluer l’intérêt du Qutenza dans la prise en charge de patients en rémission de cancer ORL et présentant des douleurs neuropathiques séquellaires. |
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| Not yet recruiting | 2 | 130 | Europe | Cutaneous patch, Oral solution, Qutenza®, Laroxyl® | INSTITUT CLAUDIUS REGAUD, DGOS | Head and neck cancer Cancer ORL, Head and neck cancer Cancer ORL, Diseases [C] - Cancer [C04] | | | | |
| Completed | 2 | 160 | | | Monash University, National Health and Medical Research Council | Painful knee osteoarthritis | | | | |
NCT06158230: Comparison of Efficacy Between Combination of Amitriptyline-propranolol and Pizotifen for Migraine Prophylaxis. |
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| Active, not recruiting | 2 | 140 | RoW | Pizotifen, Amitriptyline-propranolol | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | Migraine | 11/23 | 01/24 | | |
MACS-2, NCT05120934: Efficacy of Two Doses of Duloxetine & Amitriptyline in Interstitial Lung Disease-related Cough |
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| Recruiting | 2 | 25 | US | Amitriptyline 25 MG, Amitriptyline 50 MG, Duloxetine 30 MG, Duloxetine 60 MG, Placebo 30 MG, Placebo 60 MG | Mayo Clinic | Interstitial Lung Disease | 12/25 | 12/25 | | |
MACS-1, NCT05110144: Efficacy of Two Doses of Duloxetine and Amitriptyline in Subjects With Refractory Chronic Cough |
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| Recruiting | 2 | 50 | US | Duloxetine 30 MG, Duloxetine 60 MG, Amitriptyline 25 MG, Amitriptyline 50 MG, Placebo 30 MG, Placebo 60 MG | Mayo Clinic | Refractory Chronic Cough | 12/25 | 12/25 | | |
NCT05646693: Effect of Combined Antioxidant Therapy on Oxidative Stress Markers and Inflammatory Cytokines in Patients With Tinnitus |
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| Recruiting | 2 | 58 | RoW | Drusen Mega®, Multivitamins, Sertraline, Sertraline Hydrochloride, Placebo, Magnesium Oxide | University of Guadalajara, Institute of Experimental and Clinical Therapeutics, Hospital Civil de Guadalajara | Tinnitus, Subjective, Tinnitus, Bilateral, Antioxidant Therapy, Psychiatric Drugs, Oxidative Stress, Inflammatory Cytokines, SSRI | 12/23 | 12/24 | | |
| Active, not recruiting | 2 | 27 | Europe | Mesotherapy with mesocaine, thiocolchicoside, amitriptyline, magnesium pidolate | Polyclinique de l'Europe | Inflammatory Bowel Diseases | 12/25 | 01/26 | | |
NCT03472092: Mind and Body Approaches to Pain Reduction in Youth With Migraine |
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| Recruiting | 2 | 215 | US | Cognitive Behavioral Therapy (CBT), CBT, coping skills, mind body relaxation, Placebo, Placebo Oral Capsule, Amitriptyline, Elavil, Biofeedback-Assisted Relaxation Training (BART), Cognitive Reappraisal Training (CR) | Children's Hospital Medical Center, Cincinnati, National Institute of Neurological Disorders and Stroke (NINDS), National Center for Complementary and Integrative Health (NCCIH) | Headache, Migraine, Migraine, Migraine Disorders, Headache | 03/25 | 06/25 | | |
NCT06091553: Comparison of the Efficacy and Safety of Duloxetine Augmented With Gabapentin and Duloxetine Augmented With Amitriptyline vs Duloxetine Alone in Chemotherapy -Induced Neuropathy |
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| Recruiting | 2 | 160 | RoW | Duloxetine alone, Duloxetine augmented with gabapentin, Duloxetine augmented with amitriptyline (as combined therapy) | Beni-Suef University | Neuropathy in Cacer Patien | 09/24 | 12/24 | | |
TEC-ORL, NCT04704453: Study to Evaluate the Interest of Qutenza in Patients With Head and Neck Cancer in Remission and With Sequelae Neuropathic Pain. |
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| Recruiting | 2 | 130 | Europe | Capsaïcin patch (Qutenza®), Amitriptyline (Laroxyl®) | Institut Claudius Regaud | Head and Neck Cancer | 01/26 | 01/26 | | |
ChiCTR2100052595: A Single-Center, Open-Label, Randomized, Single-Dose, Two-Period, Two-Sequence, Crossover Study to Assess the Bioequivalence of Test Formulation Amitriptyline Hydrochloride Tablets with Reference Formulation Amitriptyline Hydrochloride Tablets in Healthy Adult Subjects under Fasting and Fed Conditions |
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| Recruiting | 1 | 50 | | TR ;RT | The First Affiliated Hospital of Zhejiang University School of Medicine; Changzhou SiYao pharmaceutical co., LTD, All funds provided by the project sponsor Changzhou SiYao pharmaceutical Co., Ltd. | depression | | | | |
RCTVM, NCT06417684: Comparison of Amitriptyline to Lifestyle Modification as Intervention for Vestibular Migraine |
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| Enrolling by invitation | 1 | 100 | US | Amitriptyline | Vanderbilt University Medical Center | Vestibular Migraine | 06/26 | 06/26 | | |
ChiCTR-OCH-14004637: Study of the Correlation between Psychiatric Symptoms of Depression and Anxiety and Serum Neuregulin-1 in Patients with Neuropathic Pain |
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| Recruiting | N/A | 60 | | Amitriptyline ;opioids ;Nerve blockers ;Nerve blockers | Jiaxing first Hospital; None, Zhejiang Medical Association | Neuropathic Pain | | | | |
ChiCTR-IOR-16009196: Transcutaneous electrical acupoint stimulation (TEAS) in the treatment of patients with globus pharyngeus |
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| Recruiting | N/A | 120 | | stimulate Tiantu for 30 mins ;stimulate sham-Tiantu for 30 mins ;stimulate Tiantu for 30 mins, twice per day for 4weeks ;amitriptyline 25mg/qn,p.o. for 4 weeks ;stimulate Tiantu for 30 mins, twice per day for 4weeks+amitriptyline 25mg/qn, p.o. for 4 weeks ;stimulate sham- Tiantu for 30 mins, twice per day for 4weeks+amitriptyline 25mg/qn, p.o. for 4 weeks ;stimulate Tiantu for 30 mins, once every other day for 8 weeks ;nothing | Guangzhou First Municipal People's Hospital, Guangzhou Nan Sha Center Hospital Affiliated to Guangzhou Medical university; Guangzhou First Municipal People's Hospital, Guangzhou Nan Sha Center Hospital Affiliated to Guangzhou Medical university, self-funding | globus pharyngeus | | | | |
ChiCTR-IOD-17011080: Dose-effect relationship of amitriptyline in patients with diarrhea-predominant irritable bowel syndrome and the Influence of CYP2D6 Genotype. |
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| Recruiting | N/A | 80 | | placebo for 4 weeks ;amitriptyline 25mg/qn, p.o, for 4 weeks ;amitriptyline 12.5mg/qn, p.o, for 4 weeks ;amitriptyline 6.25mg/qn, p.o, for 4 weeks | Guangzhou First Municipal People's Hospital, Guangzhou Nan Sha Central Hospital; Guangzhou First Municipal People's Hospital, Guangzhou Nan Sha Central Hospital, self-funding | diarrhea-predominant irritable bowel syndrome | | | | |
NCT04750967: Amitriptyline vs GON and SON Blocks in Migraine |
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| Completed | N/A | 57 | RoW | Lidocaine 1% Injectable Solution, Amitriptyline | Dr. Lutfi Kirdar Kartal Training and Research Hospital | Migraine, Headache | 01/22 | 07/23 | | |
NCT05952713: Comparative Responses to 15 Different Antidepressants in Major Depressive Disorder |
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| Completed | N/A | 73336 | Europe | Antidepressant, sertraline, citalopram, fluoxetine, paroxetine, escitalopram, reboxetine, venlafaxine, duloxetine, mirtazapine, vortioxetine, agomelatine, amitriptyline, imipramine | Mental Health Services in the Capital Region, Denmark, University of Copenhagen | Major Depressive Disorder | 07/23 | 07/23 | | |
NCT05931965: Combination Therapy of Different Antidepressants With Dietary Supplements |
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| Completed | N/A | 88 | RoW | L-methylfolate, 5-methyl-terahydrofolate, Vitamin B12, mecobalamin, magnesium, Mg | Riphah International University | Depression | 07/23 | 08/23 | | |
NCT05860062: Vitamin D Supplementation in Episodic and Chronic Tension-type Headache |
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| Recruiting | N/A | 20 | RoW | Vitamin D, colecalciferol, Calcium | Hospital de Especialidades, Centro Medico Nacional "La Raza", Instituto Mexicano del Seguro Social | Chronic Tension-Type Headache | 09/23 | 12/23 | | |
NCT06162819: Efficacy of Flunarizine Vs Amitriptyline in Prophylaxis of Migraine Prophylaxis |
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| Not yet recruiting | N/A | 84 | RoW | Amitriptyline, Amyline, Flunarizine 5mg, Sibelium | Shalamar Institute of Health Sciences | Migraine, Prophylaxis | 06/24 | 09/24 | | |
NCT05833399: Correlation of Genetic Variations With Clinical Response in Substance Use Disorder |
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| Recruiting | N/A | 200 | RoW | Quetiapine, olanzapine, mirtazapine, carbamazepine, sertraline, amitriptyline, chlorpromazine and risperidone, Seroquel, Olapex, Remeron, Tegretol, Moodapex, Tryptizol, Neurazine and Apexidone. | Alexandria University | Substance Use Disorders, Substance Dependence | 03/24 | 12/24 | | |
NCT06301061: Focal Microvibration and Chronic Lumbosacral Radicular Pain |
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| Not yet recruiting | N/A | 150 | NA | Equistasi®, Sham, No active device, Gabapentin; Pregabalin; Duloxetine; Amitriptyline, Drugs for neuropathic pain | Federico II University | Pain, Chronic, Lumbosacral Radiculopathy, Radicular; Neuropathic | 10/25 | 04/26 | | |
ChiCTR2200059876: Clinical study of different antidepressants combined with spinal cord stimulation in the treatment of subacute herpes zoster neuralgia |
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| Not yet recruiting | N/A | 80 | | Amitriptyline ;Duloxetine ;ES-ketamine ;None | The Second Xiangya Hospital of Central South University; The Second Xiangya Hospital of Central South University, Self-funded | Herpes zoster, Subacute Herpes Zoster Neuralgia | | | | |
NCT05020600: The Effect of Central Sensitization on Treatment Response in Patients With Fibromyalgia |
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| Recruiting | N/A | 40 | RoW | Duloxetine, Dyloxia, Pregabalin, Lyrica, Amitriptyline, Laroxyl | Marmara University | Central Sensitisation, Fibromyalgia | 06/24 | 12/24 | | |
NCT05279963: EA for BPS: An RCT and Study for Central Mechanism |
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| Recruiting | N/A | 84 | RoW | electroacupuncture, Amitriptyline, sham electroacupuncture | The Third Affiliated hospital of Zhejiang Chinese Medical University | Bladder Pain Syndrome | 12/24 | 01/25 | | |
NCT05708729: Neuromodulation for Central Post-stroke Pain: Mechanism, Safety and Outcome |
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| Recruiting | N/A | 32 | Europe | MCS surgery for CPSP, Vc-DBS surgery for CPSP | Universitaire Ziekenhuizen KU Leuven | Central Post-stroke Pain, CPSP | 04/26 | 04/26 | | |
NCT05889624: Responding With Evidence and Access for Childhood Headaches |
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| Recruiting | N/A | 400 | US | CBT, Cognitive Behavioral Therapy, Amitriptyline | Children's Hospital Medical Center, Cincinnati, Patient-Centered Outcomes Research Institute | Headache, Headache Disorders, Headache, Migraine, Migraine, Migraine Disorders, Migraine With Aura, Migraine Without Aura, Chronic Migraine | 07/27 | 12/27 | | |