| flecainide / Generic mfg. |
NCT00408200: A Study of the Effectiveness of Anti-Arrhythmic Medications After Atrial Fibrillation Ablation |
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| Completed | N/A | 110 | US | propafenone; flecainide; sotalol; dofetilide, Radiofrequency catheter ablation | University of Pennsylvania | Atrial Fibrillation | 04/08 | 06/08 | | |
| Completed | N/A | 60 | US | Rate Control, Toprol, Ablation Therapy, St. Jude: Livewire, Tenormin, Rate control, Inderal, Sectral, Coreg, Cardizem, Calan, Lanoxin, Rhythm Control, Rhythmol, Rhythm control, Tambacor, Betapace, Tykosin, Cordarone, Quini-glute/dex | Mayo Clinic, Duke Clinical Research Institute, Abbott Medical Devices | Atrial Fibrillation, Arrhythmia | 02/09 | 06/10 | | |
| Completed | N/A | 760 | Europe | Flecainide, Flecainide in all its approved oral preparations | Atrial Fibrillation Network, German Federal Ministry of Education and Research, Meda Pharmaceuticals, German Research Foundation | Atrial Fibrillation | 10/09 | 03/11 | | |
NCT00945867: Cytochrome P450 2D6 (CYP 450 2D6) Genotype and Flecainide Efficacy |
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| Unknown status | N/A | 100 | RoW | | Assaf-Harofeh Medical Center | Atrial Fibrillation | 03/10 | 08/10 | | |
NCT01775891: Efficacy of Pilsicainide After Radiofrequency Ablation of Paroxysmal Atrial Fibrillation |
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| Unknown status | N/A | 245 | RoW | pilsicainide, Pilsicainide (Sunrhythm®) Daiichi Sankyo, other class IC antiarrhythmic drug, flecainide 100mg bid PO or propafenone 225mg tid | Korea University | Paroxysmal Atrial Fibrillation | 07/15 | 07/15 | | |
| Unknown status | N/A | 80 | RoW | Active Acupuncture, Sham acupuncture, flecainide, tambocor | Kyunghee University Medical Center, Ministry of Health & Welfare, Korea | Persistent Atrial Fibrillation | 07/15 | 07/15 | | |
| Unknown status | N/A | 100 | Europe | Antiarrhythmic drug, medical treatment of atrial flutter, Cavo-tricuspid-isthmus-ablation, Ablation of atrial flutter, Pulmonary vein isolation | University of Rostock, Biosense Webster, Inc., Medtronic | Atrial Fibrillation, Atrial Flutter | 08/15 | 08/17 | | |
NCT02190175: Management of Atrial Fibrillation With Flecainide : the AFFLEC Study |
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| Completed | N/A | 100 | Europe | | Hellenic Cardiovascular Research Society | Atrial Fibrillation | 11/15 | 12/15 | | |
NCT01117454: Flecainide for Catecholaminergic Polymorphic Ventricular Tachycardia |
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| Completed | N/A | 14 | US | Flecainide Acetate, Placebo, Beta blocker | Vanderbilt University Medical Center | Catecholaminergic Polymorphic Ventricular Tachycardia | 12/15 | 12/15 | | |
NCT02302274: Diagnostic Value and Safety of Flecainide Infusion Test in Brugada Syndrome |
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| Completed | N/A | 209 | US | flecainide iv | NYU Langone Health | Brugada Syndrome, Arrhythmogenic Right Ventricular Cardiomyopathy | 07/17 | 07/17 | | |
| Completed | N/A | 2204 | Europe, Canada, US, RoW | Left atrial ablation, Rate or Rhythm Control Therapy | Mayo Clinic, National Heart, Lung, and Blood Institute (NHLBI), Abbott Medical Devices, Biosense Webster, Inc. | Atrial Fibrillation, Arrhythmia | 12/17 | 12/17 | | |
| Unknown status | N/A | 152 | Europe | Catheterablation, Amiodarone, Cordarone®, Sotalol, Sotalol®, Flecainide, Tambocor®, Propafenone, Rythmol®, Disopyramide, Norpace®, Dronedarone, Multaq® | Uppsala University Hospital, Swedish Heart Lung Foundation | Atrial Fibrillation, Quality of Life | 09/18 | 09/18 | | |
AVATAR-AF, NCT02459574: Ablation Verses Anti-arrhythmic Therapy for Reducing All Hospital Episodes From Recurrent Atrial Fibrillation |
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| Completed | N/A | 300 | Europe | AVATAR-AF ablation, Ablation method-surgical, Anti-Arrhythmic therapy, Amiodarone, Dronaderone, Sotalol, Beta blockers, Calcium channel blockers, Flecainide, Propafenone, Conventional AF ablation | Imperial College London | Heart Failure, Recurrent Atrial Fibrillation | 09/18 | 11/18 | | |
ACWAS, NCT02248753: Acute Cardioversion Versus Wait And See-approach for Symptomatic Atrial Fibrillation in the Emergency Department |
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| Completed | N/A | 437 | Europe | Pharmacological cardioversion - Flecainide, Flecainide, Tambocor, Electrical cardioversion, Metoprolol, Selokeen, Verapamil, Isoptin, Digoxin, Lanoxin, Pharmacological cardioversion - Amiodarone, Amiodarone, Cordarone | Maastricht University Medical Center, ZonMw: The Netherlands Organisation for Health Research and Development | Atrial Fibrillation | 11/18 | 12/19 | | |
| Completed | N/A | 200 | Europe | | IRCCS San Raffaele | Brugada Syndrome | 06/22 | 06/22 | | |
NCT03528616: Management of Supraventricular Tachycardia of Children |
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| Unknown status | N/A | 50 | NA | adenosine,Propranolol,flecainide, amiodarone, propranolol, digoxin and procainamide. | Assiut University | Supraventricular Tachycardia | 04/19 | 11/19 | | |
POWDER-AF2, NCT03437356: Pulmonary Vein Isolation With Versus Without Continued Antiarrhythmic Drugs in Persistent Atrial Fibrillation |
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| Completed | N/A | 210 | Europe | Pulmonary vein isolation using CLOSE protocol, Antiarrhythmic drug therapy (ADT) | AZ Sint-Jan AV, Biosense Webster, Inc. | Atrial Fibrillation | 05/22 | 06/22 | | |
| Active, not recruiting | N/A | 303 | Canada | Cryoballoon-based PVI, Anti-Arrhythmic Drug Therapy, sotalol, flecainide, propafenone, dronedarone | Jason Andrade, Ottawa Heart Institute Research Corporation, Medtronic, Baylis Medical Company | Atrial Fibrillation | 09/22 | 11/22 | | |
| Active, not recruiting | N/A | 303 | Canada | Cryoballoon-based PVI, Anti-Arrhythmic Drug Therapy | University of British Columbia, Ottawa Heart Institute Research Corporation, Medtronic | Atrial Fibrillation | 09/22 | 11/22 | | |
| Completed | N/A | 22 | Europe | Sotalol, Flecainide and verapamil, Catheter ablation | Maatschap Cardiologie Zwolle | Ventricular Premature Beats | 01/23 | 01/23 | | |
AVANT GUARD, NCT06096337: Pulsed Field Ablation (PFA) Versus Anti-Arrhythmic Drug (AAD) Therapy as a First Line Treatment for Persistent Atrial Fibrillation |
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| Recruiting | N/A | 387 | Europe, Canada, US, RoW | FARAPULSE™ Pulsed Field Ablation (PFA) System, Anti-Arrhythmic Drug (AAD): Flecainide, Sotalol, Propafenone, and Dofetilide | Boston Scientific Corporation | Persistent Atrial Fibrillation | 12/25 | 12/27 | | |
NCT04837261: Shortening Duration of Antiarrhythmic Medication for SVT in Infants |
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| Recruiting | N/A | 70 | Europe | Propranolol, Flecainide, Amiodarone | Tampere University Hospital, Helsinki University Central Hospital, Kuopio University Hospital, Oulu University Hospital, Turku University Hospital | Supraventricular Tachycardia | 01/24 | 01/24 | | |
EDearly AF, NCT06322017: Prospective Multicenter Randomized and Controlled Study Evaluating the Benefit of Early Pulmonary Vein Isolation Compared to Usual Treatment in Patients Aged Over 75 Years and Presenting With Atrial Fibrillation |
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| Recruiting | N/A | 294 | Europe | Rhythm control by Pulmonary Vein Isolation (PVI) procedure, Conventional care by antiarrhythmic drugs (flecainide, sotalol, amiodarone) or bradycardic drugs (all betablocker or calcium channel blocker therapy, digoxin) | Nantes University Hospital | Atrial Fibrillation | 04/28 | 04/28 | | |
FALCON, NCT05790707: EfFect of Ablation of Persistent AtriaL Fibrillation on COgNitive Function in Individuals With Mild Cognitive Impairment |
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| Recruiting | N/A | 120 | Europe | Atrial fibrillation ablation + antiarrhythmic drugs, Antiarrhythmic drug | Poitiers University Hospital | Mild Cognitive Impairment, Persistent Atrial Fibrillation | 02/25 | 02/25 | | |
NCT05084495: The Use of Flecainide for Treatment of Atrial Fibrillation |
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| Recruiting | N/A | 100 | Europe | Global peak atrial longitudinal strain and ECG | Lund University | Atrial Fibrillation | 10/25 | 10/25 | | |
