| flecainide / Generic mfg. |
2012-001898-90: Effects of vernakalant and flecainide on atrial contractility in patients with AF De effecten van vernakalant en flecaïnide op de knijpkracht van de boezems bij patiënten met boezemfibrilleren |
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| Ongoing | 4 | 50 | Europe | Brinavess, Tambocor, SUB30707, Concentrate for solution for infusion, Solution for injection, Brinavess, Tambocor | Maastricht University Medical Center, Maastricht University Medical Center | Patients with paroxysmal or persistent atrial fibrillation (AF) reporting at the first heart aid. Patiënten met paroxysmaal of persisterend atriumfibrilleren (AF) die zich melden op de eerste hart hulp., Patients with atrial fibrillation (heart rhythm disorder) reporting at the first heart aid. Patiënten met boezemfibrilleren (hartritmestoornis) die zich melden op de eerste hart hulp., Diseases [C] - Cardiovascular Diseases [C14] | | | | |
2016-003325-41: PREemptive Pharmacogenomic testing for Preventing Adverse drug REactions (PREPARE) |
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| Ongoing | 4 | 450 | Europe | Syrup, Tablet, Capsule, hard, Powder for injection, Capsule, Solution for injection, Concentrate for solution for infusion, Powder for solution for infusion, Codeine, Acenocoumarol, Amitriptyline, Aripiprazole, Atomoxetine, Atorvastatine, Azathioprine, Capecitabine, Carbamazepine, Citalopram, Clomipramine, Clopidogrel, Clozapine, Efavirenz, Escitalopram, Flecainide, Flucloxacillin, Fluorouracil, Haloperidol, Irinotecan, Mercaptopurine, Metoprolol, Oxycodone, Paroxetine, Phenprocoumon, Phenytoin, ORAP 1 mg Tabletten, Propafenone, Sertraline, Simvastatin, Tacrolimus, Tamoxifen, Tegafur, Tioguanine, Tramadol, Venlafaxine, Voriconazole, Zuclopenthixol, Ethinylestradiol, ORAP 4 mg Tabletten | Leiden University Medical Center, Leiden University Medical Center | Adverse drug reactions, Side-effects, Not possible to specify | | | | |
2018-001518-13: Elimination of ventricular premature beats and ventricular tachycardia with catheter ablation versus optimal anti-arrhythmic drug treatment Eliminatie van premature ventriculaire complexen met catheter ablatie versus optimale medicamenteuze behandeling met anti-arritmica. |
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| Not yet recruiting | 4 | 180 | Europe | Sotalol, Verapamil, Flecainide, Tablet | Maatschap Cardiologie Zwolle, Isala Zwolle | Premature ventricular beats, ventricular ectopy, ventricle tachycardia Premature ventriculaire complexen, ventriculaire extrasystolen, ventriculaire tachycardie, Premature cardiac beat Ventriculaire extrasystole (VES), Diseases [C] - Cardiovascular Diseases [C14] | | | | |
| Completed | 4 | 50 | Europe | Vernakalant, BRINAVESS, Flecainide, APOCARD | David Filgueiras-Rama, Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III | Paroxysmal Atrial Fibrillation | 06/23 | 08/23 | | |
FLIP-AF, NCT06142604: Single Dose Flecainide for Early Sinus Rhythm Conversion of Perioperative Atrial Fibrillation After Noncardiac Surgery |
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| Not yet recruiting | 4 | 20 | NA | Flecainide | Population Health Research Institute | Atrial Fibrillation, Surgery | 06/25 | 12/25 | | |
NCT02347111: Pharmacogenetic Study of Antiarrhythmic Drugs for Atrial Fibrillation |
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| Recruiting | 4 | 162 | US | Flecainide, Sotalol | University of Illinois at Chicago, Medtronic | Atrial Fibrillation | 06/25 | 06/25 | | |
2015-005743-14: Fetal atrial Flutter & Supraventricular Tachycardia (FAST) Therapy Trial |
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| Ongoing | 3 | 600 | Europe | Flecainide acetate, sotalol, Digoxin, Tablet, Injection, flecainide acetate, SOTALOL, Digoxin | St Georges University Hospital NHS Foundation Trust | Fetal atrial flutter without hydrops, supraventricular tachycardia without hydrops and supraventricular tachycardia with hydrops, fetal heart rhythm abnormalities, Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] | | | | |
| Ongoing | 3 | 110 | Europe | FLECARDIA, Ranexa, Solution for injection/infusion, Prolonged-release tablet, FLECARDIA, Ranexa | Win Medica Pharmaceuticals S.A., Win Medica Pharmaceuticals S.A. | Restoration of sinus rhythm in patients with recent AF onset Αποκατάσταση του Ï†Î»ÎµÎ²Î¿ÎºÎ¿Î¼Î²Î¹ÎºÎ¿Ï ÏÏ…Î¸Î¼Î¿Ï ÏƒÎµ ασθενείς με ΚΜ Ï€Ïοσφάτου ενάÏξεως, Restoration of sinus rhythm in patients with recent AF onset Αποκατάσταση του Ï†Î»ÎµÎ²Î¿ÎºÎ¿Î¼Î²Î¹ÎºÎ¿Ï ÏÏ…Î¸Î¼Î¿Ï ÏƒÎµ ασθενείς με ΚΜ Ï€Ïοσφάτου ενάÏξεως, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
2021-006614-37: First-line catheter ablation for early treatment of Persistent (ongoing unless cardioverted) Atrial Fibrillation (AF) – a randomized study comparing isolation of pulmonary veins triggering AF using a Cryoballoon versus antiarrhythmic medication. Kryoablation som förstahandsval för tidig behandling av persisterande (fortgående såvida inte elektrisk eller medicinsk konvertering ges) förmaksflimmer - en randomiserad studie som jämför lungvensisolering med rytmstabiliserande läkemedel. |
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| Ongoing | 3 | 220 | Europe | Tablet, tambocor, multaq, rytmonorm, sotalol | Carina Blomström Lundqvist, Swedish Research Council, Familjen Erling-Perssons Stiftelse, Swedish Heart and Lung Foundation | Persistent symptomatic atrial fibrillation Persisterande symptomatiskt förmaksflimmer, Irregular heart rhythm proved to be persistent symptomatic atrial fibrillation (chaotic rhythm in the hearts atria) that requires electrical or medical cardioversion to normal rhythm. Oregelbunden hjärtrytm som beror på ihållande förmaksflimmer som kräver medicinsk eller elektrisk konvertering för omslag till sinus rytm., Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Therapeutic techniques [E02] | | | | |
NCT02624765: Prospective Randomized Clinical Trial of Fetal Atrial Flutter & Supraventricular Tachycardia Therapy (FAST RCT) |
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| Completed | 3 | 105 | Europe, Canada, US, RoW | Digoxin (monotherapy), Sotalol (monotherapy), Flecainide (monotherapy), Digoxin (dual therapy), Sotalol (dual therapy), Flecainide (dual therapy) | Edgar Jaeggi, Canadian Institutes of Health Research (CIHR) | Fetal Atrial Flutter Without Hydrops, Fetal Supraventricular Tachycardia Without Hydrops, Fetal Supraventricular Tachycardia With Hydrops | 03/24 | 03/24 | | |
RESTORE-1, NCT05039359: Flecainide Acetate Inhalation Solution for Cardioversion of Recent-Onset, Symptomatic Atrial Fibrillation |
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| Terminated | 3 | 54 | Europe, US, RoW | FlecIH-103 | InCarda Therapeutics, Inc. | Paroxysmal Atrial Fibrillation | 05/23 | 05/23 | | |
AFLOAT, NCT05213104: Assessment of Flecainide to Lower the Patent Foramen Ovale Closure Risk of Atrial Arrhythmia or Tachycardia |
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| Active, not recruiting | 3 | 186 | Europe | Flecainide, Flecainide Acetate 150 MG | Assistance Publique - Hôpitaux de Paris, Fonds de Dotation ACTION | Patent Foramen Ovale, Atrial Arrhythmia, Cryptogenic Stroke | 02/24 | 07/26 | | |
FLECA-ED, NCT05549752: Flecainide Versus Amiodarone in the Cardioversion of Paroxysmal Atrial Fibrillation at the Emergency Department, in Patients With Coronary Artery Disease Without Residual Ischemia |
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| Recruiting | 3 | 200 | Europe | Flecainide Injectable Solution, Amiodarone Injectable Solution | Hippocration General Hospital, Win Medica, Pharmassist Ltd | Atrial Fibrillation Paroxysmal, Coronary Artery Disease Without Residual Ischemia | 10/24 | 11/24 | | |
FLECAPRO, NCT05631730: Effect and Safety of Flecainide and Metoprolol Versus Metoprolol Alone to Suppress Ventricular Arrhythmias in Arrhythmic Mitral Valve Prolapse |
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| Recruiting | 3 | 50 | Europe | Flecainide, C01B C04, Metoprolol, C07A B02 | Oslo University Hospital, The Research Council of Norway, University of Oslo | Mitral Valve Prolapse, Ventricular Arrhythmias and Cardiac Arrest | 02/26 | 02/26 | | |
NCT05939076: First-line Cryoablation for Early Treatment of Persistent Atrial Fibrillation |
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| Not yet recruiting | 3 | 220 | Europe | Pulmonary vein isolation, dronedarone - Multaq™ OR flecainide - Tambocor™ OR propafenone - Rytmonorm™ OR sotalol - Sotacor™ | Region Örebro County, The Swedish Research Council, Erling-Persson Stiftelse, Swedish Heart Lung Foundation, Uppsala University | Atrial Fibrillation, Persistent | 12/27 | 12/28 | | |
| Not yet recruiting | 3 | 1746 | NA | Medical or interventional therapy for rhythm control in atrial fibrillation (antiarrhythmic drugs, ablation, electric cardio version), Usual care for atrial fibrillation | Universitätsklinikum Hamburg-Eppendorf, University Heart & Vascular Center Hamburg, Department of Cardiology, Department of Neurology, Royal Melbourne Hospital, Melbourne Heart Centre, Royal Melbourne Hospital, Hotchkiss Brain Institute, University of Calgary, Department of Neurology and Neurosurgery, Brain Center, University Medical Center Utrecht, UMC Utrecht, Edinburgh Clinical Trials Unit, Cerebrovascular Research Group, Centre for Clinical Brain Sciences, University of Edinburgh, Department of Cardiovascular Sciences, University of Leicester British Heart Foundation Cardiovascular Research Centre, Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, CTC-NORTH, Stroke Alliance for Europe (SAFE), Kompetenznetz Vorhofflimmern e.V. (AFNET) | Acute Ischemic Stroke, Atrial Fibrillation | 09/28 | 03/29 | | |
ACTRN12608000338369: Flecainide in amyotrophic lateral sclerosis - a potential neuroprotective strategy. |
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| Recruiting | 2 | 100 | | | South Eastern Sydney Illawarra Area Health Service, A/Prof. Matthew Kiernan | Motor neuron disease, Amyotrophic lateral sclerosis | | | | |
2011-001287-22: Clinical trial of Flecainide for Catecholaminergic Ventricular Tachycardia Studio clinico sulla somministrazione di Flecainide nella tachicardia ventricolare catecolaminergica |
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| Ongoing | 2 | 10 | Europe | Tablet | FONDAZIONE SALVATORE MAUGERI - CLINICA DEL LAVORO E DELLA RIABILITAZIONE, Vanderbilt University | Patients with CPVT and ICD Pazienti con CPVT e ICD, Patients with catecholaminergic ventricular tachycardia and implantable defibrillator Pazienti con tachicardia ventricolare catecolaminergica e defibrillatore impiantabile, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
| Not yet recruiting | 2 | 10 | NA | Flecainide, Flecainide + beta-blocker | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | Andersen Tawil Syndrome, Multifocal Ectopic Purkinje-related Premature Contractions | 04/25 | 05/25 | | |
| Completed | N/A | 200 | Europe | | IRCCS San Raffaele | Brugada Syndrome | 06/22 | 06/22 | | |
| Active, not recruiting | N/A | 303 | Canada | Cryoballoon-based PVI, Anti-Arrhythmic Drug Therapy | University of British Columbia, Ottawa Heart Institute Research Corporation, Medtronic | Atrial Fibrillation | 09/22 | 11/22 | | |
| Active, not recruiting | N/A | 303 | Canada | Cryoballoon-based PVI, Anti-Arrhythmic Drug Therapy, sotalol, flecainide, propafenone, dronedarone | Jason Andrade, Ottawa Heart Institute Research Corporation, Medtronic, Baylis Medical Company | Atrial Fibrillation | 09/22 | 11/22 | | |
| Completed | N/A | 22 | Europe | Sotalol, Flecainide and verapamil, Catheter ablation | Maatschap Cardiologie Zwolle | Ventricular Premature Beats | 01/23 | 01/23 | | |
AVANT GUARD, NCT06096337: Pulsed Field Ablation (PFA) Versus Anti-Arrhythmic Drug (AAD) Therapy as a First Line Treatment for Persistent Atrial Fibrillation |
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| Recruiting | N/A | 387 | Europe, Canada, US, RoW | FARAPULSE™ Pulsed Field Ablation (PFA) System, Anti-Arrhythmic Drug (AAD): Flecainide, Sotalol, Propafenone, and Dofetilide | Boston Scientific Corporation | Persistent Atrial Fibrillation | 12/25 | 12/27 | | |
NCT04837261: Shortening Duration of Antiarrhythmic Medication for SVT in Infants |
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| Recruiting | N/A | 70 | Europe | Propranolol, Flecainide, Amiodarone | Tampere University Hospital, Helsinki University Central Hospital, Kuopio University Hospital, Oulu University Hospital, Turku University Hospital | Supraventricular Tachycardia | 01/24 | 01/24 | | |
EDearly AF, NCT06322017: Prospective Multicenter Randomized and Controlled Study Evaluating the Benefit of Early Pulmonary Vein Isolation Compared to Usual Treatment in Patients Aged Over 75 Years and Presenting With Atrial Fibrillation |
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| Recruiting | N/A | 294 | Europe | Rhythm control by Pulmonary Vein Isolation (PVI) procedure, Conventional care by antiarrhythmic drugs (flecainide, sotalol, amiodarone) or bradycardic drugs (all betablocker or calcium channel blocker therapy, digoxin) | Nantes University Hospital | Atrial Fibrillation | 04/28 | 04/28 | | |
FALCON, NCT05790707: EfFect of Ablation of Persistent AtriaL Fibrillation on COgNitive Function in Individuals With Mild Cognitive Impairment |
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| Recruiting | N/A | 120 | Europe | Atrial fibrillation ablation + antiarrhythmic drugs, Antiarrhythmic drug | Poitiers University Hospital | Mild Cognitive Impairment, Persistent Atrial Fibrillation | 02/25 | 02/25 | | |
NCT05084495: The Use of Flecainide for Treatment of Atrial Fibrillation |
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| Recruiting | N/A | 100 | Europe | Global peak atrial longitudinal strain and ECG | Lund University | Atrial Fibrillation | 10/25 | 10/25 | | |
ACTRN12621000896875: WITHDRAWal of heart failure directed therapies in recovered Atrial Fibrillation mediated cardiomyopathy- the WITHDRAW-AF study |
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| Recruiting | N/A | 60 | | | Alfred Hospital, Alfred Hospital | atrial fibrillation, heart failure | | | | |