Chronic Myeloid Leukemia  >>  pioglitazone  >>  Phase 2
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8 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
pioglitazone / Generic mfg.
ACTIM, NCT02888964: Pioglityazone and Imatinib for CML Patients

Completed
2
27
Europe
Add-on therapy
Versailles Hospital
Leukemia, Myeloid, Chronic-Phase
02/12
02/16
2009-011675-79: A PHASE II STUDY TO ASSESS EFFICACY AND SAFETY OF PIOGLITAZONE (ACTOS®) AS ADD-ON THERAPY TO IMATINIB MESYLATE (GLEEVEC®) IN CHRONIC PHASE CHRONIC MYELOGENOUS LEUKAEMIA (CP-CML) PATIENTS IN MAJOR MOLECULAR RESPONSE (MMR).

Ongoing
2
50
Europe
PIOGLITAZONE HYDROCHLORIDE, ACTOS 15 mg, ACTOS 15 mg
CH-Versailles
chronic phase chronic myelogenous leukaemia (CP-CML) patients in major molecular response.
 
 
SESPI, NCT02687425: Safety and Efficiency Study of Pioglitazone in Combination With Imatinib Mesylate to Treat Chronic Myelogenous Leukemia

Unknown status
2
20
NA
Pioglitazone, Actos, imatinib mesylate, tyrosine kinase inhibitors
Meng Li
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
11/16
06/17
NCT02730195: Pioglitazone and Tyrosine Kinase Inhibitor in Treating Patients With Relapsed Chronic Myeloid Leukemia

Terminated
2
9
US
Pioglitazone, Actos, Pioglitazone Hydrochloride, Tyrosine Kinase Inhibitor (TKI), Protein Tyrosine Kinase Inhibitors, PTK Inhibitors, TK Inhibitors
Emory University
Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive
07/18
07/18
NCT04883125: Value of Using Pioglitazone in Chronic Myeloid Leukemia Treatment

Completed
2
90
RoW
Pioglitazone 15mg, Imatinib 400mg
Mansoura University
Chronic Myelogenous Leukemia, BCR-ABL Positive, CML, Chronic Phase
04/21
04/21
PIO2STOP, NCT02889003: Second STOP After Pioglitazone Priming in CML Patients

Unknown status
2
26
Europe
Pioglitazone + TKI
Versailles Hospital, Pr Philippe ROUSSELOT
Chronic Myeloid Leukemia (CML)
12/21
12/21
EDI-PIO, NCT02852486: Study of Imatinib Discontinuation in Chronic Myeloid Leukemia With Deep Molecular Response

Active, not recruiting
2
31
RoW
Pioglitazone 30 Mg Oral Tablet, cloridrato de pioglitazona 30mg EMS S/A, Brasil, imatinib discontinuation
University of Campinas, Brazil
Leukemia, Chronic Myeloid
02/24
02/24
ACTIW, NCT02767063: Therapies in Combination or Sequentially With Tyrosine Kinase Inhibitors (TKIs) in Chronic Phase Chronic Myelogenous Leukemia Patients in CCR

Recruiting
1/2
100
Europe
Pioglitazone, Avelumab
Versailles Hospital
Leukemia, Myeloid, Chronic-Phase
11/22
06/23

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