| memantine / Generic mfg. |
NCT00234637: Rivastigmine Monotherapy and Combination Therapy With Memantine in Patients With Moderately Severe Alzheimer's Disease Who Failed to Benefit From Previous Cholinesterase Inhibitor Treatment |
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| Completed | 4 | 204 | Europe | Rivastigmine, memantine | Novartis | Alzheimer's Disease | 06/05 | 06/05 | | |
NCT00368862: Efficacy Study of Memantine Hydrochloride and Escitalopram for the Treatment of Co-Morbid Depression and Alcoholism. |
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| Completed | 4 | 80 | Europe | Ebixa (memantine hydrochloride), Cipralex (escitalopram) | Finnish Institute for Health and Welfare, Finnish Foundation for Alcohol Studies | Alcoholism, Depression | | 06/06 | | |
NCT00305903: Safety and Tolerability of Rivastigmine With Add-on Memantine in Patients With Probable Alzheimer's Disease |
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| Completed | 4 | 150 | US | Rivastigmine, memantine | Novartis | Alzheimer's Disease | | 08/07 | | |
NCT00757978: Memantine as Adjunctive Therapy for Schizophrenia Negative Symptoms |
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| Completed | 4 | 22 | RoW | memantine, Ebixa, placebo, Starch | Hospital de Clinicas de Porto Alegre | Schizophrenia | 01/08 | 03/08 | | |
NCT00505167: Memantine Versus Donepezil in Early Stages of Alzheimer's Disease |
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| Completed | 4 | 64 | Europe | Memantine, Ebixa (Memantine), Donepezil, Aricept (Donepezil) | Hospital Miguel Servet, Clinica Quiron de Zaragoza, Universidad de Zaragoza, Hospital de Barbastro, Hospital Royo Villanova | Dementia, Alzheimer Type | 07/08 | 12/08 | | |
NCT01921972: The Efficacy of a Combination Regimen in Patients With Mild to Moderate Probable Alzheimer's Disease |
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| Completed | 4 | 232 | Europe | Galantamine CR, Memantine, Placebo | Charite University, Berlin, Germany, German Federal Ministry of Education and Research | Alzheimer's Disease | 11/08 | 05/09 | | |
NCT00855686: Memantine Versus Placebo in Parkinson's Disease Dementia or Dementia With Lewy Bodies |
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| Completed | 4 | 199 | Europe | Memantine, Ebixa®, Placebo | H. Lundbeck A/S | Parkinson's Disease Dementia, Dementia With Lewy Bodies | 12/08 | 01/09 | | |
NCT00862940: A Clinical Study Evaluating the Effects of Memantine on Brain Atrophy in Patients With Alzheimer's Disease |
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| Completed | 4 | 277 | Europe | Memantine, Ebixa®, Placebo | H. Lundbeck A/S | Alzheimer's Disease | 02/09 | 04/09 | | |
| Terminated | 4 | 19 | Europe | Memantine | Merz Pharmaceuticals GmbH | Alzheimer's Disease | 05/09 | 06/09 | | |
NCT00183729: Memantine Treatment for Improving Rehabilitation Outcomes and Preventing Depression in Older Adults |
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| Completed | 4 | 35 | US | Memantine, Namenda, Placebo | Eric Lenze, National Institute of Mental Health (NIMH) | Depression | 06/09 | 06/09 | | |
| Completed | 4 | 153 | Europe | Memantine, Placebo | East Kent Hospitals University NHS Foundation Trust, University of Oxford, Institute of Psychiatry, London, University of London, University College, London, Indiana University School of Medicine | DEMENTIA | 06/09 | 09/09 | | |
NCT00768261: Corticolimbic Degeneration and Treatment of Dementia |
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| Completed | 4 | 39 | NA | Memantine (Namenda®), Namenda, Donepezil (Aricept®), Aricept | Washington University School of Medicine, Northwestern University | Dementia | 10/09 | 10/09 | | |
NCT00586573: Open-Label Pilot Study of Namenda in Adult Subjects With ADHD and ADHD NOS |
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| Completed | 4 | 34 | US | memantine hydrochloride, Namenda | Massachusetts General Hospital | ADHD | 10/09 | 10/09 | | |
NCT00401167: Memantine for Agitation and Aggression in Severe Alzheimer's Disease |
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| Completed | 4 | 31 | Canada | memantine | Sunnybrook Health Sciences Centre, Lundbeck Canada Inc. | Alzheimer's Disease | 01/10 | 01/10 | | |
| Completed | 4 | 28 | Europe | memantine, EBIXA, placebo | University Hospital, Lille | Parkinson's Disease, Gait Disorders, Neurologic | 09/10 | 10/10 | | |
NCT00800709: Memantine and Changes of Biological Markers and Brain PET Imaging in Alzheimer's Disease |
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| Completed | 4 | 26 | RoW | Memantine, Memantine hydrochloride | Shanghai Mental Health Center, H. Lundbeck A/S | Alzheimer's Disease | 10/10 | 10/10 | | |
NCT00305578: Memantine Augmentation of Lamotrigine Incomplete-Response in Bipolar Depression |
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| Completed | 4 | 29 | US | Memantine, Memantine or Namenda, Placebo | Indiana University School of Medicine | Bipolar Depression | 12/10 | 12/11 | | |
| Unknown status | 4 | 800 | Europe | Memantine, Ebixa, Donepezil, Aricept, Placebo donepezil, Placebo memantine | King's College London | Moderate to Severe Alzheimer's Disease | 02/12 | 06/13 | | |
ROMEO-AD, NCT01849042: Effect of Memantine Oral Pump on Language in Patients With Probable Alzheimer's Disease |
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| Unknown status | 4 | 188 | RoW | Ebixa, donepezil | Konkuk University Medical Center | Alzheimer's Disease, Dementia | 08/14 | 08/15 | | |
2005-004498-31: Behaviour and cognition in Alzheimer s disease patients treated with the NMDA receptor antagonist memantine collelation with the apoptotic mechanisms. |
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| Ongoing | 4 | 40 | Europe | EBIXA 10MG 56 CPR RIV, EBIXA 10MG 56 CPR RIV | FONDAZIONE SANTA LUCIA | Treatment of patients with Alzheimer s Disease | | | | |
2007-004897-26: Memantine for the Long Term Management of Neuropsychiatric Symptoms in Alzheimer\'s disease - MAIN-AD |
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| Ongoing | 4 | 300 | Europe | Memantine, Risperidone, Ebixa, Risperdal, Zyprexa, Seroquel, Haloperidol (proprietary), Ebixa, Risperdal, Zyprexa, Seroquel, Haloperidol (proprietary) | King\'s College London, North Essex Partnership NHS Foundation Trust | Alzheimer\'s disease | | | | |
2010-024543-33: Can memantine prevent memory impairment induced by MDMA in humans |
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| Completed | 4 | 16 | Europe | Memantine, MDMA, MDMA, Ebixa, Ebixa | Maastricht University | none | | | | |
NCT02553928: Comparison of Once Daily and Twice Daily Dosing on Safety and Tolerability of Memantine in Patients With Alzheimer |
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| Completed | 4 | 62 | RoW | Memantine (once daily), Lu 00-800, Ebixa ®, Ebix ®, Memantine (twice daily) | H. Lundbeck A/S | Alzheimer Dementia (AD) | 07/16 | 07/16 | | |
NCT01656187: Attenuation of Corticosteroid Induced Hippocampal Changes |
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| Completed | 4 | 46 | US | Memantine 10 mg capsule, Namenda, Memantine-matched Placebo capsule, Sugar pill | University of Texas Southwestern Medical Center, National Institute on Drug Abuse (NIDA) | Organic Memory Impairment | 01/17 | 01/17 | | |
2016-004097-17: The main purpose of this clinical trial is to introduce a method for dertermination drugs in biological samples ( plasma, cerebrospinal fluid or urine ) and their subsequent use. HlavnÃm cÃlem je zavést metodu pro stanovenà léÄiva v biologických vzorcÃch ( plasma, mozkomÃÅ¡nà mok, popÅ™. moÄ ) a jejà následné využitÃ. |
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| Completed | 4 | 32 | Europe | MEMANTINE TEVA, Capsule, MEMANTINE TEVA | Fakultni nemocnice Hradec Kralove, Neurologická klinika Fakultnà nemocnice Hradec Králové | Alzheimer's disease Alzheimerova choroba, Alzheimer's disease Alzheimerova choroba, Diseases [C] - Nervous System Diseases [C10] | | | | |
NCT03168997: Memantine Treatment in Alzheimer's Disease Patients |
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| Unknown status | 4 | 222 | NA | Memantine Hydrochloride, Memantine | Wei Cuibai | Alzheimer Disease | 09/18 | 12/18 | | |
NCT01902004: Brain Aging and Treatment Response in Geriatric Depression |
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| Completed | 4 | 115 | US | Escitalopram, Lexapro, Memantine, Namenda, Placebo, inactive substance | University of California, Los Angeles, National Institute of Mental Health (NIMH) | Mild Cognitive Impairment (MCI), Depression | 01/19 | 01/19 | | |
NCT03860597: Memantine Effects on Sensorimotor Gating and Neurocognition in Schizophrenia |
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| Completed | 4 | 42 | US | Memantine, Placebos | University of California, San Diego | Schizophrenia, Schizo Affective Disorder, Schizoaffective Disorder, Healthy | 03/21 | 03/21 | | |
| Completed | 4 | 30 | Canada | Memantine Hydrochloride 10 mg, PrSANDOZ MEMANTINE FCT10 mg Drug Identification Number (DIN) 02375532 | Kenneth Myers, MD | Epileptic Encephalopathy, Childhood-Onset | 11/21 | 02/22 | | |
| Completed | 4 | 132 | Europe | Donepezil, Memantine, Measurement of serum level of anti-dementia drug | Zealand University Hospital, Filadelfia Epilepsy Hospital | Dementia, Dementia With Lewy Bodies, Dementia in Parkinsons Disease, Dementia Alzheimers, Alzheimer Disease | 02/23 | 02/23 | | |
NCT03954613: Evaluation of the Contribution of Regular Cognitive Exercises to Treatment in Patients With Alzheimer's Disease |
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| Recruiting | 4 | 198 | RoW | Ebicomb, Donepezil-Memantine | Neutec Ar-Ge San ve Tic A.Åž | Alzheimer Disease, Cognitive Change | 03/23 | 03/24 | | |
ChiCTR2000035209: Effects of Memantine on glutamate metabolism in patients with moderate to severe depression: a randomized controlled trial. |
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| Not yet recruiting | 4 | 60 | | combination therapy ;Anti-5-ht antidepressant should be administered alone | The Second Affiliated Hospital of Xinxiang Medical University; The Second Affiliated Hospital of Xinxiang Medica University, Henan Provincial Clinical Research Center for Mental and Psychological Diseases opens the project | depression | | | | |
NCT03703856: Biomarker Predictors of Memantine Sensitivity in Patients With Alzheimer's Disease |
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| Recruiting | 4 | 32 | US | Memantine, Placebo | University of California, San Diego | Alzheimer Disease | 06/24 | 06/24 | | |
NCT05430867: Efficacy and Safety of Memantine and Sodium Oligomannate in Patients With Moderate to Severe Alzheimer's Disease |
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| Not yet recruiting | 4 | 150 | NA | Memantine Oral Tablet, Memantine, GV-971 capsule, GV-971 | First Affiliated Hospital Xi'an Jiaotong University | Treatment, Efficacy, Safety, Alzheimer Disease | 07/24 | 12/24 | | |
ChiCTR2300071719: Evaluation of the efficacy and safety of Memantine hydrochloride oral membranes in the treatment of moderate-to-severe and severe senile dementia patients in real-world settings: a multicenter registry study |
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| Not yet recruiting | 4 | 2000 | | N/A | The Second Hospital, Cheeloo College of Medicine, Shandong University; The Second Hospital, Cheeloo College of Medicine, Shandong University, enterprise | Senile dementia | | | | |
