Not yet recruiting

N/A

211

 

Royal Children's Hospital, Royal Children's Hospital

Bronchiolitis

 

 

Completed

N/A

300

RoW

solu medrol, a steroid-free immunosuppression protocol

Shanghai Jiao Tong University School of Medicine, First Affiliated Hospital of Fujian Medical University, Nanchang University, Zhejiang University, Shanghai Changzheng Hospital

Immunosuppression, Hepatocellular Carcinoma, Liver Transplantation, Post-operative Complications

01/08

12/09

Completed

N/A

25

Europe

intra-articular infiltration, epidural infiltration

Centre Hospitalier Universitaire Vaudois

Diabetes, Healthy

09/08

06/10

Terminated

N/A

47

US

methylprednisolone, treatment group, azithromycin, control group

Chongqing Medical University

Refractory Mycoplasma Pneumoniae Pneumonia

05/10

05/10

Completed

N/A

30

RoW

Corticosteroid, Solu-Medrol

Beijing Anzhen Hospital, National Natural Science Foundation of China

Heart Valve Diseases, Systemic Inflammatory Response Syndrome

04/11

08/11

Completed

N/A

77

US

methylprednisolone (IVMP), Solumedrol, Steroid, glucocorticoid, methylprednisolone (two doses IVMP)

Medical University of South Carolina

Congenital Heart Disease, Disorder of Fetus or Newborn

09/11

09/11

Completed

N/A

121

US

Hydrocortisone High Dose, Solumedrol, Corticosteroid, Steroid, Hydrocortisone Low Dose

Cedars-Sinai Medical Center

Orthostatic Hypotension, Hemodynamic Instability, Fever, Hypothermia

04/12

04/12

Completed

N/A

200

 

epidural dexamethasone injection ;epidural methylprednisolone injection

Department of ICU, The third affiliated Hospital of Harbin Medical University; Level of the institution：, None

lumbar pain postoperative

 

 

Completed

N/A

150

Europe

Methylprednisolone, Solu-Medrol, Pfizer., Physiological Saline, Physiological Saline 9 mg/ml, Fresenius Kabi

Louise de la Motte

Abdominal Aortic Aneurysms

01/13

04/13

Completed

N/A

233

US

Antiemetic anesthesia protocol, Scopolamine 1.5 milligram(mg) patch, Propofol infusion, remifentanil infusion, 250mg erythromycin po for 2 doses, Solumedrol, 0.625mg IV droperidol, 4mg IV Ondansetron, Ketorolac 30mg IV, ibuprofen 600mg po q6h, Fentanyl, Hydrocodone/Tylenol po

University of North Carolina, Chapel Hill, National Institute of Dental and Craniofacial Research (NIDCR)

Post-operative Nausea, Post-operative Vomiting, Nausea Persistent

02/14

04/14

Unknown status

N/A

120

RoW

methylprednisolone

Third Affiliated Hospital, Sun Yat-Sen University

Severe Acute Exacerbation of Chronic Hepatitis B

08/14

11/14

Unknown status

N/A

132

Europe

Arthrographic distention, Hydrodilatation, Intra-articular corticosteroid Depo Medrol

Imelda Hospital, Bonheiden, Universitaire Ziekenhuizen Leuven

Adhesive Capsulitis, Frozen Shoulder

12/14

11/15

Completed

N/A

26

NA

Methylprednisolone

Piotr Miskiewicz

Graves' Disease, Graves Ophthalmopathy, Blood Coagulation, Venous Thromboembolism

12/14

12/14

Completed

N/A

177

US

Donor pain management

Northwestern University, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Liver Diseases, Hepatocellular Cancer, Endstage Liver Disease, Liver Cirrhosis

05/15

04/18

Unknown status

N/A

50

Canada

Ultrasound, methylprednisolone

Université de Sherbrooke

Carpal Tunnel Syndrome

10/15

12/15

Completed

N/A

32

NA

Methylprednisolone

Medical University of Warsaw

Graves Disease, Graves Ophthalmopathy, Hypertension, Blood Pressure, Heart Failure

12/15

12/15

Recruiting

N/A

125

 

intratympanic methylprednisolone perfusion (0.5ml/day,40mg/ml) ;intravenous methylprednisolone 80mg/day×4day, 40mg/day×3day, 20mg/day×3day ;Not treatment

Nanjing Drum Tower Hosipital, Nanjing University Medical School; Nanjing Drum Tower Hosipital, Nanjing University Medical School, National Science Funds of China

Sudden Sensorineural Hearing Loss

 

 

Completed

N/A

30

Europe

Methylprednisolone, Solu-Medrol, Placebo, Sodium Chloride

Sahlgrenska University Hospital, Sweden

Aortic Stenosis

02/17

02/17

Completed

N/A

22

RoW

rituximab, rituximab injection, cyclophosphamide, cyclophosphamide injection, Steroids, methylprednisolone, Intravenous immunoglobulin, IVIG

First Affiliated Hospital of Zhejiang University

Cognitive Impairment, Autoimmune Encephalitis

02/18

02/18

Completed

N/A

42

Europe

Methyl-Prednisolone, Solu-Medrol, Physiological saline, Physiological Saline 9 mg/ml, Fresenius Kabi

Kristian Kiim Jensen

Hernia, Ventral

05/18

11/18

Completed

N/A

15

Europe

Corticosteroid injection, Solumedrol

Elza Abdessater

Corticosteroids Adverse Reaction

06/18

06/18

Completed

N/A

17

Europe

cochlear implantation

Oticon Medical

Cochlear Implant

10/18

10/18

Terminated

N/A

6

RoW

Prednisone, Glucocorticoid, MP and CTX, Glucocorticoid and immunosuppressive agents

Wenhu Liu

Idiopathic Membranous Nephropathy

01/19

06/19

Completed

N/A

30

Canada

Tacrolimus, Advagraf

University of British Columbia, Astellas Pharma Canada, Inc.

Acute Graft Rejection, Diabetes

02/19

10/19

Withdrawn

N/A

0

RoW

Autologous Fecal Microbiota Transplantation

Rambam Health Care Campus

Fecal Microbiota Transplantation in Graft vs. Host Disease

03/20

03/20

Completed

N/A

173

Europe

Methylprednisolone, standard care

University of Trieste

Severe Acute Respiratory Syndrome (SARS) Pneumonia, Coronavirus Infections, ARDS, Human

05/20

05/20

Unknown status

N/A

40

Europe

Therapeutic plasma exchanges, Conventional treatment of AE-IPF

Assistance Publique - Hôpitaux de Paris

Exacerbation of Idiopathic Pulmonary Fibrosis

10/20

03/21

Recruiting

N/A

200

RoW

Methylprednisolone Injectable Product, solu madrol

Lahore General Hospital

SARS-CoV Infection, SARS (Severe Acute Respiratory Syndrome)

12/20

12/20

Recruiting

N/A

48

 

Methylprednisolone, intravenous injection, 1-2mg/kg·d for 3 days. ;Without any glucocorticoid therapy

Chongqing Public Health Medical Center; Chongqing Public Health Medical Center, Chongqing Science and Technology of Bureau

Novel Coronavirus Pneumonia (COVID-19)

 

 

Recruiting

N/A

246

 

Intravenous methylprednisolone 120mg at anesthetic induction; Dexmedetomidine infusion at a rate of 0.4ug/kg/h after induction until the end of surgery; Volatile anesthetic to maintain anesthesia. ;Use the same technique to give the same amount or rate of normal saline at the same time point mentioned above, and use total intravenous anesthesia (propofol) throughout the surgery to maintain anesthesia

West China Hospital, Sichuan University; West China Hospital, Sichuan University, self-raised

postoperative recovery and perioperative organ protection

 

 

Not yet recruiting

N/A

180

 

Intravenous methylprednisolone andintratympanic injection ;Intravenous methylprednisolone +intratympanic injection+intravenous of Ginaton ;shock dose hormone group

Eye & ENT Hospital of Fudan University; Eye &ENT Hospital of Fudan University, The 2018 annual science and technology innovation action plan project of Shanghai municipal science and technology commission

the idiopathic sudden deafness with vertigo

 

 

Completed

N/A

36

RoW

Eltrombopag, Revolade, conventional, solumedrol, imuran, cellcept, mabthera, gammaglobulin

Nayera Hazaa Elsherif

Idiopathic Thrombocytopenic Purpura

09/21

09/21

Enrolling by invitation

N/A

100

RoW

aerosol inhalation of glucocorticoids, intravenous injection of glucocorticoids

Dong Yang, Jilin University

Acute Exacerbation of Chronic Obstructive Pulmonary Disease

12/24

07/25

Withdrawn

N/A

0

US

Blood sample collection for coagulation profile, Clinical data collection

St. Joseph's Hospital and Medical Center, Phoenix

Multiple Sclerosis

12/21

03/22

Recruiting

N/A

142

RoW

Corticosteroid & Plasma exchange, CS+PE, Corticosteroid, CS

Chinese PLA General Hospital

Optic Neuritis

12/21

12/21

Not yet recruiting

N/A

135

 

common medical treatment, combined with methylprednisolone 40mg intravenously once a day, discontinued after 5 days ;common medical treatment, combined with the Zidaxian 1.6mg subcutaneous injection once a day, discontinued after 5 days. ;Routine medical treatment.

Zhejiang University; The Third Affiliated Hospital, SUN YAT-SEN University, Ministry of Finance，China

HBV-ACLF

 

 

Completed

N/A

90

RoW

extracorporeal Shock wave therapy, an Auto Wave 695 (Mettler electronics, USA) brand device, Corticosteroid injection, methylprednisolone, Kinesiotaping, KinesioTex, KinesioTaping, US

Harran University, Sanliurfa Education and Research Hospital

Plantar Fascitis

04/22

07/22

Not yet recruiting

N/A

390

 

plasma exchange ;Lymphatic plasma exchange ;Intravenous immunoglobulin ;plasma exchange ;Lymphatic plasma exchange ;Intravenous immunoglobulin ;plasma exchange ;Lymphatic plasma exchange ;Methylprednisolone Intravenous Shock ;plasma exchange ;Lymphatic plasma exchange ;Methylprednisolone Intravenous Shock ;Intravenous immunoglobulin

Department of Neurology, Xiangya Hospital, Central South University; Xiangya Hospital, Central South University, Self-raised

Severe Neuroimmune Disease

 

 

Withdrawn

N/A

0

NA

40mg Triamcinolone Injections in the Bladder

The University of Texas Medical Branch, Galveston

Interstitial Cystitis, Bladder Pain Syndrome

03/23

03/23

Recruiting

N/A

218

RoW

Surgical treatment of round window niche enlargement via round window for inner ear drug delivery, Drum chamber drug injection

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Hearing Loss, Sudden

11/23

03/24

Not yet recruiting

N/A

1200

RoW

Combination group, Standard group

National Taiwan University Hospital

Cardiac Arrest, Out-Of-Hospital Cardiac Arrest, Emergency Medical Services

06/26

12/26

Not yet recruiting

N/A

103

 

Intravenous methylprednisolone (40mg/ day) was used for 1-3 days during hospitalization; Intravenous methylprednisolone (40mg/ day) was used for 4-7 days during hospitalization ;No systemic hormones were used during hospitalization

Shenzhen Second People's Hospital; Shenzhen Second People's Hospital, Funding from hospital-level clinical research projects in 2021

chronic obstructive pulmonary disease

 

 

Recruiting

N/A

86

RoW

Receive traditional medical therapy and transcranial direct current stimulation, Receive traditional medical therapy and sham stimulation

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Tinnitus, Subjective, Sudden Deafness, Transcranial Direct Current Stimulation, Double-Blind Method, Female, Male, Human, Treatment Outcome

08/24

08/24

Not yet recruiting

N/A

50

 

Mahuang, Kuxingren, Gancao, Fengfang, Dilong, Chishao, Jiezi, Laifuzi, Zisuzi, Huangqi, Huangqin, Qinghao ;1. All patients will take pulmonary rehabilitation therapy; 2. Patients with hypoxia at rest, will take long-term oxygen therapy; 3. Patients with pulmonary infection will take empirical anti-infective treatment, and targeted anti-infective treatment will be given after obtaining the results of drug sensitivity test. For the dosage of hormones and immunomodulators, our recommendations are summarised below: (1) Glucocorticoid: the initial dose of glucocorticoid can range from oral prednisone (1mg·kg-1·d-1) to intravenous methylprednisolone (500-1000 mg/d) for 3 days, then reduced to prednisone or equivalent dose, gradually reduced to maintenance dose in 4-8 weeks according to the patient's condition and treatment response, and maintained close follow-up; (2) Cyclophosphamide: adhere to the daily use of 2mg, the initial dose is prescribed daily oral 25mg-50mg, and increase 25mg every other week to two weeks, according to this cycle until the maximum dose reaches the daily 150mg; (3) Azathioprine: administered at 2-3 mg·kg-1·d-1. The initial dose is 25-30mg/d, and then 25mg will be increased every 7 to 14 days until the maximum amount of 150mg/d is reached; In addition, if the subjects had taken oral corticosteroids for more than one month before entering the trial, and the hormone had reached the maintenance dose, or if they had taken oral immunomodulators for more than one month before entering the trial, the original drug treatment regimen should not be changed during the clinical observation, the investigators should record it completely and truthfully.

Hospital of Chengdu University of Traditional Chinese Medicine; Beijing University of Chinese Medicine, National Natural Science Foundation of China (No.81973713)

progressive pulmonary fibrosis（PPF）

 

 

Not yet recruiting

N/A

106

 

Induction remission stage: Glucocorticoid + cyclophosphamide; Maintain remission stage: Hormone + azathioprine / methotrexate / mycophenolate mofetil ;Induction remission stage: Methylprednisolone + intravenous cyclophosphamide or rituximab; Maintain remission stage: Hormone + azathioprine / mycophenolate mofetil / rituximab ;Induction: Methylprednisolone + cyclophosphamide + rituximab + plasma exchange; Maintain: Hormone + azathioprine / mycophenolate mofetil / rituximab ;Induction: Methylprednisolone + intravenous cyclophosphamide; Maintain: Hormone + azathioprine / methotrexate / mycophenolate mofetil

Children's Hospital Affiliated to Chongqing Medical University; Children's Hospital Affiliated to Chongqing Medical University, self-financing

ANCA associated glomerulonephritis

 

 

Not yet recruiting

N/A

50

NA

Inebilizumab, oral immunosuppressant

Xuanwu Hospital, Beijing, Jiangsu Hansoh Pharmaceutical Co., Ltd.

Neuromyelitis Optica Spectrum Disorder

07/25

07/25

Recruiting

N/A

142

Europe

Lidocaine, Methylprednisolone Acetate, Depo-Medrol, Dexamethasone

C.L.A.Vleggeert-Lankamp, Spaarne Gasthuis, Stichting Achmea Gezondheidszor, Posthumus Meyjes Fonds

Sciatica, Sciatica Due to Intervertebral Disc Disorder, Sciatic Radiculopathy

12/25

07/26