methylprednisolone sodium succinate / Generic mfg. 
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215 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
methylprednisolone sodium succinate / Generic mfg.
ChiCTR-TRC-11001454: Tacrolimus monotherapy follows intravenous methylprednisolone in adults with minimal change nephrotic syndrome: a prospective, multi-centered, open, randomized, controlled trial

Completed
4
120
 
Tacrolimus orally taken 0.5-1mg q12h for 36w, tape ;prednisone orally taken for 36w, 1.0 mg/kg.d, tape
Kidney Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University; Kidney Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, Kidney Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University
minimal change disease in adults
 
 
2010-018289-21: Clinical, laboratory and ultrasound markers for the prediction of the response on the pulse-dose treatment by intravenous glucocorticoids in patients with endocrine orbitopathy

Ongoing
4
45
Europe
Solu-Medrol, not applicable, Powder and solvent for solution for injection, Solu-Medrol
Insitute of Endocrinology
active severe endocrine orbitopathy
 
 
ChiCTR-TRC-10001162: Methylprednisolone for primary supratentorial intracerebral hemorrhage: a randomized double-blind, placebo-controlled trial in postoperativepatients

Completed
4
100
 
conventional medica treatment+placebo ;Methylprednisolone 80 mg via intravenous infusion once per 12 hours for 72 hours+conventional medical treatment
West China Hospital, Sichuan University; West China Hospital, Sichuan University, Self-funding
Postoperation acute primary supratentorial intracerebral hemorrhage
 
 
CTIMRPMSAGO, ChiCTR-IPR-15006848: Comparison of two intravenous methylprednisolone regimens for patients with moderate to severe and active Graves’ ophthalmopathy

Completed
4
40
 
Two doses of MP monthly for 3 months
Department of Endocrinology and Metabolism, the Affiliated Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology; None, self-financing
Graves' ophthalmopathy
 
 
ChiCTR-TRC-10001141: Methylprednisolone for primary intracerebral hemorrhage: a randomized double-blind, placebo-controlled trial

Completed
4
100
 
Methylprednisolone 80 mg via intravenous infusion once per 12 hours for 72 hours+conventional medical treatment ;Placebo+conventional medical treatment
West China Hospital, Sichuan University; Level of the institution：, Self-funding
Acute primary supratentorial intracerebral hemorrhage
 
 
2013-001196-20: EFFICACY OF STEROIDS IN THE TREATMENT OF DYSTHYROID OPTIC NEUROPATHY EFFICACIA DEGLI STEROIDI NEL TRATTAMENTO DELL'OTTICOPATIA DISTIROIDEA ACUTA

Ongoing
4
70
Europe
SOLUMEDROL, 83-43-2, Powder and solution for solution for injection, SOLUMEDROL
FONDAZIONE IRCCS CA' GRANDA OSPEDALE MAGGIORE POLICLINICO MILANO, FONDAZIONE IRCCS CA' GRANDA OSPEDALE MAGGIORE POLICLINICO
GRAVES' ORBITOPATHY ORBITOPATIA DI GRAVES, GRAVES' ORBITOPATHY ORBITOPATIA DI GRAVES, Diseases [C] - Immune System Diseases [C20]
 
 
2005-002391-14: Pulsed Intravenous Methylprednisolone for Ocular Pemphigoid- A Pilot Study

Ongoing
4
20
Europe
Solu-Medrone, Solu-Medrone
Moorfields Eye Hospital NHS Foundation Trust
ocular mucous membrane pemphigoid
 
 
2006-000607-42: Treatment of borderline changesin protocol biopsy 3 months after renal transplantation

Ongoing
4
30
Europe
SOLU-MEDROL inj.
Institute for clinical and experimental Medicine
Patients with transplanted kidney and stabilised graft function
 
 
2006-005803-33: ÉTUDE PILOTE OBSERVATIONNELLE CHEZ DES PATIENTES SOUFFRANT D’UN CANCER DU SEIN ET RECEVANT UNE CHIMIOTHÉRAPIE ÉMÉTISANTE TRAITÉES PAR UNE DOSE UNIQUE DE ALOXI® (PALONOSÉTRON) 0,25 MG ASSOCIÉE À UNE CORTICOTHÉRAPIE

Ongoing
4
150
Europe
ALOXI, SOLU-MEDROL, ALOXI, SOLU-MEDROL
THERABEL LUCIEN PHARMA
The prevention of acute or delayed Chemotherapy-Induced Nausea and Vomiting (CINV) by the combination of palonosetron 250 microgrammes and methylprednisolone 80 mg in patients receiving a first administration of a first line of emetogenic chemotherapy to treat their non metastatic breast cancer.
 
 
2007-006780-70`ACTRN12621000229875: METYYLIPREDNISOLONIN IMEYTYMINEN VAIKEAA KOLIITTIA SAIRASTAVILLASuonensisäistä ja suun kautta tapahtuvaa annostelua vertaileva lääkeainepitoisuusmäärityksiin perustuva tutkimus

Ongoing
4
10
Europe
Medrol, Solu-Medrol
Tampereen yliopistollinen sairaala, Clinical Project Grant reviewed by Royal Adelaide Hospital Research Committee
needle fear, haemodialysis patients
 
 
2008-007413-76: Metyyliprednisolonin farmakokinetiikka ja -dynamiikka lasten avosydänleikkausten yhteydessä

Ongoing
4
105
Europe
Solu-Medrol
Pertti Suominen
Lasten ja nuorten sairaalassa (HUS) hoidettavat 1-12 kk ikäiset avosydänleikkaukseen tulevat potilaat, joilla on sydänvikanan TOF, AVSD tai VSD.Lasten ja nuorten sairaalassa (HUS) hoidettavat korkeintaan 28 päivän ikäiset avosydänleikkaukseen tulevat potilaat, joilla on sydänvikana TGA, HLHS tai IAA.
 
 
2011-000899-33: Rituximab treatment in patients with tjyroid associated that do not respond to intravenous steroids or relapse after intravenous steroid treatment

Ongoing
4
50
Europe
mabthera, metotrexate, Solu-Medrol, Prednisolon, Mabthera, metotrexate, Solu-Medrol, Prednisolon, Mabthera, metotrexate, Solu-Medrol, Prednisolon
Department of Endocrinology, Sahlgrenska University Hospital
Thyroid associated opthalmopathy
 
 
2012-004451-37: pain management after videoscopic pulmonary surgery with pills, local analgesic and with or without adrenocortical hormone. Smertebehandling efter kikkert-lungekirurgi med piller, smertekateter og med eller uden binyrebarkhormon.

Ongoing
4
100
Europe
Solu-Medrol, Solu-Medrol
Per F. Jensen, Rigshospitalet
Pain after thoracoscopic surgery Smerter efter video-assisteret thorakoskopisk kirurgi
 
 
ChiCTR-OPB-15006526: Quantitative assessment of TCR repertoire after standardized treatment in Graves' Ophthalmopathy

Recruiting
4
10
 
high-dose intravenous methylprednisolone pulse (IVMP) therapy
First Affiliated Hospital of Xi’an Jiaotong University Health Science Center; First Affiliated Hospital of Xi'an Jiaotong University Health Science Center, National Natural Science Foundation of China
Graves‘ Ophthalmopathy
 
 
ChiCTR-IPR-16009576: A randomized, single-blind, controlled clinical trial design to evaluate the effectiveness and safety of methylprednisolone in patients with early post-operative hyperbilirubinemia after liver transplantation from donation after citizen’s death

Recruiting
4
60
 
Methylprednisolone 1mg/Kg iv qd + Ursodeoxycholic Acid 250mg po tid for 5 days ;Ursodeoxycholic Acid 250mg po tid for 5 days
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University; The First Affiliated Hospital, Sun Yat-sen University, Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University
Early post-operative hyperbilirubinemia after liver transplantation
 
 
2017-000622-35: Different dosis of corticosteroids in mandibular third molar surgery. En randomiserede undersøgelse af forskellige doser af kortikosteroid på smerte, hævelse og gabeevne efter kirurgisk fjernelse af visdomstænder i underkæben.

Ongoing
4
52
Europe
Methylprednisolone, SUB08872MIG, Concentrate and solvent for solution for injection, Solu-medrol®
Aalborg University Hospital, None
The purpose is to investigate the postoperative morbidity after removal of mandibular third molar with different doses of methylprednisolone., The purpose is to investigate the postoperative morbidity after removal of mandibular third molar with different doses of methylprednisolone., Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Surgical Procedures, Operative [E04]
 
 
ChiCTR-IPR-17013049: Effects of via methylprednisolone inhibits mast cell degranulation on postoperative cognitive dysfunction in elderly patients

Not yet recruiting
4
100
 
Preoperative intravenous injection of methylprednisolone ;Preoperative intravenous injection of the same amount of saline
The First Affiliated Hospital, University of South China; The First Affiliated Hospital, University of South China, Private expenses
postoperative cognitive dysfunction
 
 
2018-004205-12: Methylprednisolone injection in treatment of birch pollen induced allergic rhinitis

Not yet recruiting
4
60
Europe
Depo-medrol, Injection, Depo-Medrol® Injektionsvätska, suspension 40 mg/ml
Region Skåne, Region Skåne
Seasonal birch pollen induced allergic rhinitis, Pollen allergy, Body processes [G] - Circulatory and Respiratory Physiological Phenomena [G09]
 
 
ChiCTR-IPR-17010472: Methylprednisolone plus cyclophosphamide in thyroid associated ophthalmopathy

Recruiting
4
120
 
Cyclophosphamide+methylprednisolone ;Methylprednisolone
Shanghai Changzheng Hospital; Shanghai Changzheng Hospital, Second Military Medical University
thyroid associated ophthalmopathy
 
 
2018-004083-62: Effect of intramuscular corticosteroid injection on the post-operative swelling, trismus and pain following lower third molar surgery Alsó bölcsességfog eltávolításnál a műtét előtt közvetlenül a rágóizomba juttatott szteroid hatásai a műtét következményeként kialakuló duzzanatra, szájzárra és fájdalomra

Not yet recruiting
4
30
Europe
Powder and solution for solution for injection, Solu-Medrol
Semmelweis University, Oro-Maxillofacial Surgery and Stomatology, Semmelweis University, Oro-Maxillofacial Surgery and Stomatology
post-operative swelling, trismus, pain posztoperatív duzzanat, szájzár, fájdalom, post-operative swelling, trismus, pain műtét következményeként kialakuló duzzanat, szájzár, fájdalom, Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Dentistry [E06]
 
 
ACTRN12612000252819: A Randomised Controlled trial of intravenous immunoglobulin (IVIg) compared with pulse methyl-prednisolone for the treatment of chronic active antibody mediated rejection

Terminated
4
50
 
Dr William Mulley, National Blood Authority
chronic active antibody mediated rejection of the renal allograft
 
 
ChiCTR1900024125: Effect of intravenous injection of different doses of methylprednisolone on maternal fever rate and maternal and infant outcome in labor analgesia

Recruiting
4
300
 
Intravenous preinjection of NS ;intravenous injection of methylprednisolone 10mg ;intravenous injection of methylprednisolone 20mg
Zhujiang Hospital of Southern Medical University; Zhujiang Hospital of Southern Medical University, self-financing
Fever after labor analgesia
 
 
NCT02378298: Rituximab (RTX) Therapy in Patients With Active TAO

Active, not recruiting
4
26
Europe
Rituximab, Mabthera, Rituxan, Zytux, L01XC02, Iv Methylprednisolone, Solumedrol, peroral methylprednisolone and Methotrexate, Prednisolone
Göteborg University, Sahlgrenska University Hospital, Sweden
Ophthalmopathy, Thyroid-Associated
02/20
12/24
ChiCTR2000028818: Clinical efficacy of different treatment routes of methylprednisolone in rescure treatment of sudden deafness: a randomized controlled trial

Not yet recruiting
4
170
 
Apply methylprednisolone 48mg/d throughout the day for 7 days, then gradually reduce the amount for 3 days for a total of 10 days. At the same time, 40 mg / mL methylprednisolone was injected into the tympanic cavity every 2 days during the treatment period, a total of 5 times. ;The whole body was treated with methylprednisolone 48mg/d for 7 days, then gradually reduced for 3 days for a total of 10 days.
The First Affiliated Hospital, Sun Yat-Sen University; The First Affiliated Hospital, Sun Yat-Sen University, project of Guangzhou sciences revolution plan
Idopathic sudden sensorineural hearing loss
 
 
2021-004737-37: The effect of corticosteroids on early recovery after major surgery in elderly patients_CORTERAS STUDY

Not yet recruiting
4
674
Europe
Concentrate and solvent for solution for injection/infusion, Solu-medrol
Ziekenhuis Oost-Limburg, Ziekenhuis Oost-Limburg
major surgery• off-pump coronary bypass surgery• on-pump coronary bypass surgery• Aortic Valve Replacement Mini Access Surgery• laparoscopic hemicolectomies• thoracoscopic lung resections• femoral popliteal and tibial bypass surgery• laparoscopic radical prostatectomies, major surgery (cardial, abdominal, vascular surgery), Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]
 
 
NCT04622917: Methylprednisolone Injections Treating Birch Pollen Induced Allergic Rhinitis.

Completed
4
44
Europe
MethylPREDNISolone 40 Mg/mL Injectable Suspension, Depo-Medrol, NaCl 9 MG/ML Injectable Solution, Sodium Chloride
Karolinska Institutet
Rhinitis, Allergic, Seasonal, Hay Fever, Pollen Allergy, Allergic Rhinitis
06/22
05/23
ChiCTR2000037658: A randomized controlled, open-label, phase II study aimed to evaluate the efficacy and safety of topical or systemic glucocorticoid therapy for grade 2 immune-related pneumonitis

Recruiting
4
40
 
Inhalation budesonide 2mg 3 times per day ;intravenous methylprednisolone 1~2mg/kg
Shanghai Pulmonary Hospital; Shanghai Pulmonary Hospital, Shanghai Shenkang Hospital Development Center
Lung Cancer
 
 
NCT06041451: Early and Late Prognosis in Patients With Guillain-Barre Syndrome

Recruiting
4
450
RoW
Intravenous Immunoglobulins, Human, Methylprednisolone 500 MG Injection
First Affiliated Hospital of Wenzhou Medical University
Guillain-Barre Syndrome
12/22
01/25
NCT05824390: A Randomized, Controlled Clinical Study of Rituximab in Treatment of Primary IgA Nephropathy

Active, not recruiting
4
116
RoW
rituximab group, ACEi and / or ARB
XIEJINGYUAN, Dongfang Hospital Affiliated to Tongji University, Shanghai Pudong New Area People's Hospital, Ruijin Hospital North Shanghai Jiao Tong University School of Medicine, Ningbo Municipal Yinzhou District No.2 Hospital, Third Affiliated Hospital, Sun Yat-Sen University, Xiamen Hongai Hospital, Sir Run Run Shaw Hospital
IgA Nephropathy
10/23
10/23
NCT05604859: Evaluate the Efficacy and Safety of Various Treatment Schemes for Severe Fever With Thrombocytopenia Syndrome(SFTS)

Recruiting
4
350
RoW
Methylprednisolone, intravenous immunoglobulin, Tocilizumab, Low molecular weight heparin, conventional treatment
Qin Ning
Severe Fever With Thrombocytopenia Syndrome
12/23
06/24
STPARS, NCT05969522: Stratified Therapy on Pediatric AAGN

Recruiting
4
200
RoW
GlucoCorticoid, Rituximab, Cyclophosphamide
Wang Mo
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, ANCA-Associated Glomerulonephritis
12/23
12/25
NCT05329740: Glucocorticoids for Post-operative Patients With Acute Type A Aortic Dissection (The GLAD Trial)

Completed
4
212
RoW
Methylprednisolone Injection
Shanghai Zhongshan Hospital
Methylprednisolone, Glucocorticoid, Aortic Dissection, Organ Dysfunction
11/23
11/23
NCT06510114: A Randomized Clinical Trial of Intravenous Methylprednisolone With 2 Protocols in Patients With Graves Orbitopathy

Not yet recruiting
4
150
NA
methylprednisolone(daily scheme), prednisone, methylprednisolone(weekly scheme)
Third Affiliated Hospital, Sun Yat-Sen University
Graves Ophthalmopathy
06/26
12/26
GLUCO-TAVR, NCT06076824: Glucocorticoid Treatment in Transaortic Valve Replacement to Reduce the Incidence of Conduction Disturbances ().

Recruiting
4
100
Europe
Methylprednisolone, Placebo, Saline solution
Hospital General Universitario de Alicante
Heart Block, Aortic Stenosis, Bundle-Branch Block
09/24
09/24
NCT06474273: TACKLE-IT Trial - Treat Acute T Cell Rejection With Evidence and Confidence in Kidney Transplant Recipients

Not yet recruiting
4
540
Canada, RoW
Methylprednisolone, IV MP, Prednisone
University of Sydney, University of Manitoba
Rejection; Transplant, Kidney, Rejection; Transplant, Pancreas
12/29
12/29
NCT05927233: Effect of Methylprednisolone on Systemic Inflammatory Response During Pediatric Congenital Open-Heart Surgery

Recruiting
4
60
RoW
Methylprednisolone, Saline
Aga Khan University
Cyanotic Heart Disease, Cardiopulmonary Bypass
04/25
06/25
MyCITS, NCT05495893: MMF Versus CYC in the Induction Therapy of Pediatric Active Proliferative LN

Recruiting
4
224
RoW
Cyclophosphamide, Mycophenolate Mofetil
Second Xiangya Hospital of Central South University, Peking Union Medical College Hospital, Children's Hospital of Chongqing Medical University, Beijing Children's Hospital, Jiangxi Province Children's Hospital, The Affiliated Hospital of Qingdao University, Shenzhen Children's Hospital, The First Affiliated Hospital of Zhengzhou University, The Children's Hospital of Zhejiang University School of Medicine, The Second Hospital of Hebei Medical University
Mycophenolate Mofetil, Cyclophosphamide, Lupus Nephritis
05/25
05/25
NCT05867329: A Trial for Acute Severe Ulcerative Colitis

Recruiting
4
162
US
Cyclosporine Injection (IV), Sandimmune, Cyclosporine Oral Product, Upadacitinib Extended Release Oral Tablet, Rinvoq, Intravenous Methylprednisolone, Solu-Medrol, Prednisone Oral Product, Rayos
Berinstein, Jeffrey
Ulcerative Colitis Acute
05/26
05/26
GLUREDLUP, NCT05207358: Minimizing Glucocorticoid Administration in Patients With Proliferative Lupus Nephritis

Recruiting
4
30
Europe
Rituximab, Mycophenolate Mofetil, Cyclophosphamide, Corticosteroids
Institutul Clinic Fundeni
Lupus Nephritis
12/28
12/28
ACTRN12623000340639: Budesonide versus prednisolone after liver transplantation: a phase 3, open label, non-inferiority randomised controlled trial

Recruiting
3
100
 
Austin Health, Austin Health Medical Research Foundation
Liver transplantation, Allograft rejection
 
 
2005-005375-15: Efficacy of maintenance therapy with rituximab after induction chemotherapy (R-CHOP vs R-FC) for elderly patients with mantle cell lymphoma not suitable for autologous stem cell transplantation

Ongoing
3
570
Europe
Mabthera, ENDOXAN, Adriablastine, Vincrisin, Fludara, Medrol, Solu-Medrol, Ro45 2994, Concentrate for solution for infusion, Powder for solution for injection, Solution for injection, Powder and solvent for solution for injection, Tablet
GELA
Mantle cell lymphoma
 
 
2007-003910-33: Randomized controlled study of rituximab and steroid treatment in thyroid-associeted ophthalmopathy (TAO)

Ongoing
3
60
Europe
Concentrate for solution for infusion, Powder and solvent for solution for injection, MABTHERA, SOLUMEDROL
OSPEDALE MAGGIORE DI MILANO (IRCCS)
Thyroid associeted ophthalmopathy.
 
 
2017-000845-39: Effectiveness of anti TNFalpha agents in Behcet¿s disease Efficacia dei farmaci anti TFN alfa nella patologia del Beh¿et

Not yet recruiting
3
46
Europe
HUMIRA, INFLECTRA, MEDROL, SOLU MEDROL, HUMIRA, INFLECTRA, SOLU MEDROL, Solution for injection, Powder for solution for injection, Tablet, Powder and solvent for solution for injection, HUMIRA - 40 MG SOLUZIONE INIETTABILE USO SOTTOCUTANEO 1 SIRINGA PRERIEMPITA 0.8 ML + 1 TAMPONE IMBEVUTO DI ALCOL IN UN BLISTER, INFLECTRA - 100 MG - POLVERE PER CONCENTRATO PER SOLUZIONE PER INFUSIONE - USO ENDOVENOSO - FLACONCINO (VETRO) - 1 FLACONCINO, MEDROL - 4 MG COMPRESSE 30 COMPRESSE, SOLU MEDROL - 500 MG/8 ML POLVERE E SOLVENTE PER SOLUZIONE INIETTABILE 1 FLACONE DI POLVERE DA 500 MG+ FIALA SOLVENTE DA 8 ML, SOLU MEDROL - 40 MG/ML POLVERE E SOLVENTE PER SOLUZIONE INIETTABILE 1 FLACONE A DOPPIA CAMERA DA 40 MG/ML
AZIENDA OSPEDALIERO-UNIVERSITARIA PISANA, AIFA - Italian Medicines Agency
BEH¿ET¿S DISEASE REFRACTORY TO STANDARD OF CARE THERAPIES Malattia di Beh¿et refrattaria alle terapie standard, BEH¿ET¿S DISEASE REFRACTORY TO STANDARD OF CARE THERAPIES Malattia di Beh¿et refrattaria alle terapie standard, Diseases [C] - Immune System Diseases [C20]
 
 
2017-005034-36: Study evaluating the effect of rituximab in patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) Studio che valuta l'effetto del farmaco rituximab nei pazienti con poliradicoloneuropatia cronica infiammatoria demielinizzante (CIDP) in trattamento cronico con immunoglobuline

Ongoing
3
60
Europe
Rituximab, Paracetamolo, Metilprednisolone sodio succinato, Clorfenamina maleato, [Rituximab], [Paracetamolo], [Metilprednisolone sodio succinato], [Clorfenamina maleato], Concentrate for solution for infusion, Tablet, Powder and solvent for solution for injection, Solution for injection, MABTHERA - 1 FIALA 500 MG 50 ML, TACHIPIRINA - 1000 MG COMPRESSE 8 COMPRESSE, SOLU MEDROL - 125 MG/2 ML POLVERE E SOLVENTE PER SOLUZIONE INIETTABILE 1 FLACONE A DOPPIA CAMERA DA 125 MG/2 ML, TRIMETON - 10 MG/1 ML SOLUZIONE INIETTABILE 5 FIALE 1 ML
IRCCS ISTITUTO CLINICO HUMANITAS, AIFA - Italian Medicines Agency
Chronic inflammatory demyelinating polyradiculoneuropathy Poliradicoloneuropatia cronica infiammatoria demielinizzante, Chronic inflammatory demyelinating polyradiculoneuropathy Polineuropatia cronica infiammatoria demielinizzante, Diseases [C] - Nervous System Diseases [C10]
 
 
2017-004606-18: Terapia di disassuefazione con metilprednisolone e diazepam ev in pazienti affetti da cefalea cronica con uso eccessivo di sintomatici Terapia di disassuefazione con metilprednisolone e diazepam ev in pazienti affetti da cefalea cronica con uso eccessivo di sintomatici

Ongoing
3
284
Europe
valium, METILPREDNISOLONE, 0430315, Solution for injection, VALIUM - 10MG/2ML SOLUZIONE INIETTABILE 3 FIALE DA 2ML, SOLU MEDROL - 125 MG/2 ML POLVERE E SOLVENTE PER SOLUZIONE INIETTABILE 1 FLACONE A DOPPIA CAMERA DA 125 MG/2 ML
UNIVERSITÀ CAMPUS BIO-MEDICO DI ROMA, UNIVERSITA' CAMPUS BIO-MEDICO DI ROMA
Emicrania Cronica e Cefalea da Iperuso di Farmaci Emicrania Cronica e Cefalea da Iperuso di Farmaci, Emicrania Cronica e Cefalea da Iperuso di Farmaci Emicrania Cronica e Cefalea da Iperuso di Farmaci, Diseases [C] - Nervous System Diseases [C10]
 
 
2017-002511-34: Intravenous immunoglobulin and intravenous methylprednisolone as optimal induction treatment in CIDP(OPTIC trial) Intraveneus immunoglobuline en intraveneus methylprednisolon als optimale inductie behandeling in CIDP(OPTIC trial)

Ongoing
3
96
Europe
Methylprednisolon (Solu-Medrol), Sodium Chloride 0.9%, RVG 56083, Concentrate for solution for infusion, Solution for infusion, Methylprednisolone (Solu-Medrol), Sodium Chloride 0.9%
Academisch Medisch Centrum, Princes Beatrix Spierfonds, ZonMW, Sanquin
Chronic inflammatory demyelinating polyneuropathy (CIDP) Chronische inflammatoïre demyeliniserende polyneuropathie (CIDP), Chronic inflammatory demyelinating neuropathy (CIDP) is a disorder of the peripheral nerves which leads to loss of muscle strength and / or sensory loss in the arms and legs Chronische inflammatoïre demyeliniserende polyneuropathie (CIDP) is een zenuwontsteking van de perifere zenuwen resulterend in krachtverlies en/of gevoelsstoornissen aan armen en benen., Diseases [C] - Nervous System Diseases [C10]
 
 
2018-003565-33: . Intérêt de la corticothérapie préopératoire sur la cicatrisation après ostéosynthèse des fractures du membre inférieur

Not yet recruiting
3
120
Europe
Concentrate for solution for injection, Solution for injection, METHYLPREDNISOLONE, CHLORURE DE SODIUM
CHU de Clermont-Ferrand
FRACTURE DE LA JAMBE, FRACTURE DE LA JAMBE, Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Surgical Procedures, Operative [E04]
 
 
2019-002310-39: Vasopressin and steroids in addition to adrenaline in cardia arrest in hospital Vasopressin och steroider som tillägg till adrenalin vid hjärtstopp på sjukhus

Not yet recruiting
3
1400
Europe
Empressin, Adrenaline, Injection, Powder and solvent for emulsion for injection, Empressin, Solu-medrol, Solu-Cortef, Adrenalin
Norrtälje Sjukhus, Tiohundra AB
In hospital cardiac arrest Hjärtstopp på sjukhus där adrenalin ska ges enligt europeiska riktlinjer, In hospital cardiac arrest when adrenaline is supposed to be given according to european guidlines Hjärtstopp på sjukhus där adrenalin ska ges enligt europeiska riktlinjer, Diseases [C] - Cardiovascular Diseases [C14]
 
 
2020-001921-30: Steroids and unfractionated heparin in critically-ill patients with pneumonia from COVID-19 infection. A multicenter, interventional, randomized, three arms study design. Steroidi e eparina non frazionata in pazienti critici con polmonite da COVID-19. Disegno di studio multicentrico, interventistico, randomizzato con tre bracci.

Ongoing
3
200
Europe
Metilprednisolone sodio succinato, VERACER, enoxaparina sodica, [-], Powder and solvent for solution for injection, Concentrate for solution for injection, SOLU MEDROL, VERACER, inhixa
AZIENDA OSPEDALIERO-UNIVERSITARIA POLICLINICO DI MODENA, Fondo ricerca Aziendale
critically-ill patients with pneumonia from COVID-19 infection Pazienti critici ventilati per polmonite e severa insufficienza respiratoria da SARS-CoV-2, critically-ill patients with pneumonia from COVID-19 infection Pazienti critici ventilati per polmonite e severa insufficienza respiratoria da SARS-CoV-2, Diseases [C] - Virus Diseases [C02]
 
 
STAUNCH-19, NCT04528888: Steroids and Unfractionated Heparin in Critically Ill Patients With Pneumonia From COVID-19 Infection

Recruiting
3
210
Europe
Enoxaparin, Inhixa, Methylprednisolone, solu-medrol, unfractionated heparin, Veracer
Massimo Girardis
Covid19, SARS-CoV Infection, Pneumonia, Viral, Coagulopathy
06/21
07/21
2021-000938-34: Study to assess the safety and efficacy of high dose pulse intravenous corticosteroid therapy to treat patients with complicated/fulminant acute myocarditis, randomly comparing this treatment with standard therapy Studio per valutare la sicurezza e l'efficacia della terapia corticosteroide endovenosa ad alte dosi per il trattamento di pazienti affetti da miocardite acuta complicata/fulminante, confrontando in modo casuale questo trattamento con la terapia standard

Ongoing
3
288
Europe
Metilprednisolone, [Metilprednisolone], Powder and solvent for solution for injection, SoluMedrol- Methylprednisolone
AZIENDA OSPEDALIERA AO OSPEDALE NIGUARDA CA' GRANDA, Antwerp University Hospital, Ministero della Salute - Bando Ricerca Finalizzata 2019 - giovane ricercatore, the Italian Ministry of Health (GR-2019-12368506)
Complicated/fulminant acute myocarditis Miocardite acuta complicata/fulminante, Severe cardiac inflammation Infiammazione cardiaca grave, Diseases [C] - Cardiovascular Diseases [C14]
 
 
AALL1131, NCT01406756 / 2014-001866-90: Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia

Recruiting
3
4895
US, Canada, Europe, RoW
Clofarabine, Clofarex, Clolar, Cyclophosphamide, (-)-Cyclophosphamide, 2H-1,3,2-Oxazaphosphorine, 2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide, monohydrate, Carloxan, Ciclofosfamida, Ciclofosfamide, Cicloxal, Clafen, Claphene, CP monohydrate, CTX, CYCLO-cell, Cycloblastin, Cycloblastine, Cyclophospham, Cyclophosphamid monohydrate, Cyclophosphamidum, Cyclophosphan, Cyclophosphane, Cyclophosphanum, Cyclostin, Cyclostine, Cytophosphan, Cytophosphane, Cytoxan, Fosfaseron, Genoxal, Genuxal, Ledoxina, Mitoxan, Neosar, Revimmune, Syklofosfamid, WR- 138719, Cytarabine, .beta.-Cytosine arabinoside, 1-.beta.-D-Arabinofuranosyl-4-amino-2(1H)pyrimidinone, 1-.beta.-D-Arabinofuranosylcytosine, 1-Beta-D-arabinofuranosyl-4-amino-2(1H)pyrimidinone, 1-Beta-D-arabinofuranosylcytosine, 1.beta.-D-Arabinofuranosylcytosine, 2(1H)-Pyrimidinone, 4-Amino-1-beta-D-arabinofuranosyl-, 2(1H)-Pyrimidinone, 4-amino-1.beta.-D-arabinofuranosyl-, Alexan, Ara-C, ARA-cell, Arabine, Arabinofuranosylcytosine, Arabinosylcytosine, Aracytidine, Aracytin, Aracytine, Beta-Cytosine Arabinoside, CHX-3311, Cytarabinum, Cytarbel, Cytosar, Cytosar-U, Cytosine Arabinoside, Cytosine-.beta.-arabinoside, Cytosine-beta-arabinoside, Erpalfa, Starasid, Tarabine PFS, U 19920, U-19920, Udicil, WR-28453, Dexamethasone, Aacidexam, Adexone, Aknichthol Dexa, Alba-Dex, Alin, Alin Depot, Alin Oftalmico, Amplidermis, Anemul mono, Auricularum, Auxiloson, Baycuten, Baycuten N, Cortidexason, Cortisumman, Decacort, Decadrol, Decadron, Decalix, Decameth, Decasone R.p., Dectancyl, Dekacort, Deltafluorene, Deronil, Desamethasone, Desameton, Dexa-Mamallet, Dexa-Rhinosan, Dexa-Scheroson, Dexa-sine, Dexacortal, Dexacortin, Dexafarma, Dexafluorene, Dexalocal, Dexamecortin, Dexameth, Dexamethasonum, Dexamonozon, Dexapos, Dexinoral, Dexone, Dinormon, Fluorodelta, Fortecortin, Gammacorten, Hexadecadrol, Hexadrol, Lokalison-F, Loverine, Methylfluorprednisolone, Millicorten, Mymethasone, Orgadrone, Spersadex, Visumetazone, Doxorubicin Hydrochloride, 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8, 9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride, (8S-cis)- (9CI), ADM, Adriacin, Adriamycin, Adriamycin Hydrochloride, Adriamycin PFS, Adriamycin RDF, ADRIAMYCIN, HYDROCHLORIDE, Adriamycine, Adriblastina, Adriblastine, Adrimedac, Chloridrato de Doxorrubicina, DOX, DOXO-CELL, Doxolem, Doxorubicin.HCl, Doxorubin, Farmiblastina, FI 106, FI-106, hydroxydaunorubicin, Rubex, Etoposide, Demethyl Epipodophyllotoxin Ethylidine Glucoside, EPEG, Lastet, Toposar, Vepesid, VP 16-213, VP-16, VP-16-213, Hydrocortisone Sodium Succinate, (11beta)-21-(3-Carboxy-1-oxopropyl)-11,17-dihydroxypregn-4-ene-3,20-dione, Monosodium Salt, A-Hydrocort, Buccalsone, Corlan, Cortisol Sodium Succinate, Cortop, Efcortelan, Emergent-EZ, Flebocortid, Hidroc Clora, Hycorace, Hydro-Adreson, Hydrocort, Hydrocortisone 21-Sodium Succinate, Hydrocortisone Na Succinate, Kinogen, Nordicort, Nositrol, Sinsurrene, Sodium hydrocortisone succinate, Solu-Cortef, Solu-Glyc, Laboratory Biomarker Analysis, Leucovorin Calcium, Adinepar, Calcifolin, Calcium (6S)-Folinate, Calcium Folinate, Calcium Leucovorin, Calfolex, Calinat, Cehafolin, Citofolin, Citrec, Citrovorum Factor, Cromatonbic Folinico, Dalisol, Disintox, Divical, Ecofol, Emovis, Factor, Citrovorum, Flynoken A, Folaren, Folaxin, FOLI-cell, Foliben, Folidan, Folidar, Folinac, Folinate Calcium, folinic acid, Folinic Acid Calcium Salt Pentahydrate, Folinoral, Folinvit, Foliplus, Folix, Imo, Lederfolat, Lederfolin, Leucosar, leucovorin, Rescufolin, Rescuvolin, Tonofolin, Wellcovorin, Mercaptopurine, 3H-Purine-6-thiol, 6 MP, 6 Thiohypoxanthine, 6 Thiopurine, 6-Mercaptopurine, 6-Mercaptopurine Monohydrate, 6-MP, 6-Purinethiol, 6-Thiopurine, 6-Thioxopurine, 6H-Purine-6-thione, 1,7-dihydro- (9CI), 7-Mercapto-1,3,4,6-tetrazaindene, Alti-Mercaptopurine, Azathiopurine, BW 57-323H, Flocofil, Ismipur, Leukerin, Leupurin, Mercaleukim, Mercaleukin, Mercaptina, Mercaptopurinum, Mercapurin, Mern, NCI-C04886, Puri-Nethol, Purimethol, Purine, 6-mercapto-, Purine-6-thiol (8CI), Purine-6-thiol, monohydrate, Purinethiol, Purinethol, U-4748, WR-2785, Methotrexate, Abitrexate, Alpha-Methopterin, Amethopterin, Brimexate, CL 14377, CL-14377, Emtexate, Emthexat, Emthexate, Farmitrexat, Fauldexato, Folex, Folex PFS, Lantarel, Ledertrexate, Lumexon, Maxtrex, Medsatrexate, Metex, Methoblastin, Methotrexate LPF, Methotrexate Methylaminopterin, Methotrexatum, Metotrexato, Metrotex, Mexate, Mexate-AQ, MTX, Novatrex, Rheumatrex, Texate, Tremetex, Trexeron, Trixilem, WR-19039, Pegaspargase, L-Asparaginase with Polyethylene Glycol, Oncaspar, PEG-Asparaginase, PEG-L-Asparaginase, PEG-L-Asparaginase (Enzon - Kyowa Hakko), PEGLA, Polyethylene Glycol L-Asparaginase, Polyethylene Glycol-L-Asparaginase, Prednisone, .delta.1-Cortisone, 1, 2-Dehydrocortisone, Adasone, Cortancyl, Dacortin, DeCortin, Decortisyl, Decorton, Delta 1-Cortisone, Delta-Dome, Deltacortene, Deltacortisone, Deltadehydrocortisone, Deltasone, Deltison, Deltra, Econosone, Lisacort, Meprosona-F, Metacortandracin, Meticorten, Ofisolona, Orasone, Panafcort, Panasol-S, Paracort, PRED, Predicor, Predicorten, Prednicen-M, Prednicort, Prednidib, Prednilonga, Predniment, Prednisonum, Prednitone, Promifen, Servisone, SK-Prednisone, Radiation Therapy, Cancer Radiotherapy, Irradiate, Irradiated, Irradiation, RADIATION, Radiotherapeutics, Radiotherapy, RT, Therapy, Radiation, Thioguanine, 2-Amino 6MP, 2-Amino-1,7-dihydro-6H-purine-6-thione, 2-Amino-6-mercaptopurine, 2-Amino-6-purinethiol, 2-Aminopurin-6-thiol, 2-Aminopurine-6(1H)-thione, 2-Aminopurine-6-thiol, 2-Mercapto-6-aminopurine, 6-Amino-2-mercaptopurine, 6-Mercapto-2-aminopurine, 6-Mercaptoguanine, 6-TG, 6H-Purine-6-thione, 2-amino-1,7-dihydro- (9CI), BW 5071, Lanvis, Tabloid, Tioguanin, Tioguanine, Wellcome U3B, WR-1141, X 27, Vincristine Sulfate, Kyocristine, Leurocristine Sulfate, Leurocristine, sulfate, Oncovin, Vincasar, Vincosid, Vincrex, Vincristine, sulfate
Children's Oncology Group, National Cancer Institute (NCI)
B Acute Lymphoblastic Leukemia, Bone Necrosis, Central Nervous System Leukemia, Cognitive Side Effects of Cancer Therapy, Neurotoxicity Syndrome, Pain, Testicular Leukemia, Therapy-Related Toxicity, Untreated Adult Acute Lymphoblastic Leukemia, Untreated Childhood Acute Lymphoblastic Leukemia
08/21
 
NCT03692416: The Effect of Some Drugs Used in Treatment of Vasculitis on the Complement System in Children

Active, not recruiting
3
70
RoW
Ibuprofen, Advil, Prednisone, Deltasone Oral or Solu-Medrol IV, Methotrexate, Rheumatrex
Assiut University
Vasculitis
11/21
05/22
AHOD1331, NCT02166463: Brentuximab Vedotin and Combination Chemotherapy in Treating Children and Young Adults With Stage IIB, Stage IIIB, IVA, or IVB Hodgkin Lymphoma

Checkmark Approved for 1L high-risk Hodgkin lymphoma in children and young adults based on AHOD1331 trial
Nov 2022 - Nov 2022: Approved for 1L high-risk Hodgkin lymphoma in children and young adults based on AHOD1331 trial
Checkmark Submitted for 1L high-risk Hodgkin lymphoma in children [Based on AHOD1331 trial]
Jul 2022 - Jul 2022: Submitted for 1L high-risk Hodgkin lymphoma in children [Based on AHOD1331 trial]
Checkmark Data from the AHOD1331 trial in children with newly diagnosed high-risk Hodgkin lymphoma at ASCO 2022
More
Active, not recruiting
3
600
Canada, US
Bleomycin Sulfate, Blanoxan, BleMomycine, Blenoxane, Bleo-cell, Bleo-S, Bleocin, Bleolem, Bleomycin Sulfas, Bleomycin Sulphate, Bleomycini Sulfas, Blexane, Oil Bleo, Brentuximab Vedotin, ADC SGN-35, Adcetris, Anti-CD30 Antibody-Drug Conjugate SGN-35, Anti-CD30 Monoclonal Antibody-MMAE SGN-35, Anti-CD30 Monoclonal Antibody-Monomethylauristatin E SGN-35, cAC10-vcMMAE, SGN 35, SGN-35, SGN35, Cyclophosphamide, (-)-Cyclophosphamide, 2H-1,3,2-Oxazaphosphorine, 2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide, monohydrate, Asta B 518, B 518, B-518, B518, Carloxan, Ciclofosfamida, Ciclofosfamide, Cicloxal, Clafen, Claphene, CP monohydrate, CTX, CYCLO-cell, Cycloblastin, Cycloblastine, Cyclophospham, Cyclophosphamid monohydrate, Cyclophosphamide Monohydrate, Cyclophosphamidum, Cyclophosphan, Cyclophosphane, Cyclophosphanum, Cyclostin, Cyclostine, Cytophosphan, Cytophosphane, Cytoxan, Fosfaseron, Genoxal, Genuxal, Ledoxina, Mitoxan, Neosar, Revimmune, Syklofosfamid, WR 138719, WR- 138719, WR-138719, WR138719, Doxorubicin Hydrochloride, 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8, 9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride, (8S-cis)- (9CI), ADM, Adriacin, Adriamycin, Adriamycin Hydrochloride, Adriamycin PFS, Adriamycin RDF, ADRIAMYCIN, HYDROCHLORIDE, Adriamycine, Adriblastina, Adriblastine, Adrimedac, Chloridrato de Doxorrubicina, DOX, DOXO-CELL, Doxolem, Doxorubicin HCl, Doxorubicin.HCl, Doxorubin, Farmiblastina, FI 106, FI-106, FI106, hydroxydaunorubicin, Rubex, Etoposide, Demethyl Epipodophyllotoxin Ethylidine Glucoside, EPEG, Lastet, Toposar, Vepesid, VP 16, VP 16-213, VP 16213, VP-16, VP-16-213, VP-16213, VP16, VP16213, Laboratory Biomarker Analysis, Methylprednisolone, Adlone, Caberdelta M, DepMedalone, Depo Moderin, Depo-Nisolone, Duralone, Emmetipi, Esametone, Firmacort, Medlone 21, Medrate, Medrol, Medrol Veriderm, Medrone, Mega-Star, Meprolone, Methylprednisolonum, Metilbetasone Solubile, Metrocort, Metypresol, Metysolon, Predni-M-Tablinen, Prednilen, Radilem, Sieropresol, Solpredone, Summicort, Urbason, Veriderm Medrol, Wyacort, Pharmacological Study, Prednisone, .delta.1-Cortisone, 1, 2-Dehydrocortisone, Adasone, Cortancyl, Dacortin, DeCortin, Decortisyl, Decorton, Delta 1-Cortisone, Delta-Dome, Deltacortene, Deltacortisone, Deltadehydrocortisone, Deltasone, Deltison, Deltra, Econosone, Lisacort, Meprosona-F, Metacortandracin, Meticorten, Ofisolona, Orasone, Panafcort, Panasol-S, Paracort, Perrigo Prednisone, PRED, Predicor, Predicorten, Prednicen-M, Prednicort, Prednidib, Prednilonga, Predniment, Prednisone Intensol, Prednisonum, Prednitone, Promifen, Rayos, Servisone, SK-Prednisone, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration, Vincristine Sulfate, Kyocristine, Leurocristine Sulfate, Leurocristine, sulfate, Oncovin, Vincasar, Vincosid, Vincrex, Vincristine, sulfate
National Cancer Institute (NCI)
Ann Arbor Stage IIB Hodgkin Lymphoma, Ann Arbor Stage IIIB Hodgkin Lymphoma, Ann Arbor Stage IVA Hodgkin Lymphoma, Ann Arbor Stage IVB Hodgkin Lymphoma, Childhood Hodgkin Lymphoma, Classic Hodgkin Lymphoma
12/21
09/24
2021-004529-57: A Phase 3 Study of Itolizumab in Combination with Corticosteroids for the Initial Treatment of Acute Graft Versus Host Disease (Complication of Bone Marrow Transplants) Uno studio di fase 3 su Itolizumab in combinazione con corticosteroidi per il trattamento iniziale della malattia acuta del trapiantocontro l'ospite (complicanza dei trapianti di midollo osseo)

Not yet recruiting
3
400
Europe
Methylprednisolone, Itolizumab, [-], Powder and solvent for solution for injection, Powder for solution for injection/infusion, SOLU MEDROL
Equillium Inc., Equillium, Inc., Equillium, Inc.
Acute Graft Versus Host Disease Malattia acuta da trapianto contro l'ospite, Acute Graft Versus Host Disease (Complication of Bone Marrow Transplants) Malattia acuta da trapianto contro l'ospite (complicanza dei trapianti di midollo osseo), Body processes [G] - Immune system processes [G12]
 
 
RESET, NCT05187793: Study of Efficacy of Different Treatment Regimens of Olokizumab

Active, not recruiting
3
198
RoW
Olokizumab, Standard therapy
R-Pharm, Federal Budget Institution of Science "Central Research Institute of Epidemiology" of the Rospotrebnadzor, Group of companies Medsi, JSС
COVID-19
10/22
04/23
ZUMA-7, NCT03391466 / 2017-002261-22: Study of Effectiveness of Axicabtagene Ciloleucel Compared to Standard of Care Therapy in Patients With Relapsed/Refractory Diffuse Large B Cell Lymphoma

Checkmark Data from ZUMA-7 trial (Abstract #659) in 2L DLBCL at ASH 2022
Dec 2022 - Dec 2022: Data from ZUMA-7 trial (Abstract #659) in 2L DLBCL at ASH 2022
Checkmark Data from ZUMA-7 trial (Abstract #259) in 2L DLBCL at ASH 2022
Dec 2022 - Dec 2022: Data from ZUMA-7 trial (Abstract #259) in 2L DLBCL at ASH 2022
Checkmark Data from ZUMA-7 trial for 2L DLBCL at ASCO 2022
More
Active, not recruiting
3
359
Europe, Canada, US, RoW
Axicabtagene Ciloleucel, KTE-C19, axi-cel, Yescarta ®, Platinum-containing salvage chemotherapy (eg, R-ICE) followed by high dose therapy (eg, BEAM) and autologous stem cell transplant in responders., Cyclophosphamide, Fludarabine
Kite, A Gilead Company
Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
03/21
11/24
Ocarina II, NCT05232825 / 2020-005448-48: A Phase III, Non-Inferiority, Randomized, Open-Label, Parallel Group, Multicenter Study To Investigate The Pharmacokinetics, Pharmacodynamics, Safety And Radiological And Clinical Effects Of Subcutaneous Ocrelizumab Versus Intravenous Ocrelizumab In Patients With Multiple Sclerosis

Hourglass Jan 2023 - Dec 2023 : Data from Ocarina II trial for multiple sclerosis
Hourglass Apr 2022 - Jul 2022 : First patient in of P3 Ocarina II trial for multiple sclerosis
Active, not recruiting
3
236
Europe, US, RoW
Ocrelizumab IV, RO4964913, Ocrelizumab SC, Methylprednisolone IV, Diphenhydramine IV, Dexamethasone given orally, Desloratadine given orally
Hoffmann-La Roche
Relapsing Multiple Sclerosis, Primary Progressive Multiple Sclerosis
04/25
04/25
MTX-aGVHD, NCT03371667: To Compare the Efficacy of the Addition of Methotrexate (MTX) to Current Standard Acute Graft-versus-host Disease (GVHD) First-line Treatment With Corticosteroids

Active, not recruiting
3
102
Europe
Methotrexate, Placebo
Assistance Publique - Hôpitaux de Paris
Allogeneic Disease, GVH - Graft Versus Host Reaction, GVHD, Acute, Stem Cell Transplant Complications
12/24
12/24
EFRAIM II, NCT04680884: Empirical Steroids and/or Antifungals in Immunocompromised Patients With Acute Respiratory Failure From Undetermined Etiology: a Multicenter Double-blind Randomized Controlled Trial

Not yet recruiting
3
420
NA
Experimental for steroid, Experimental for antifungals, Experimental for steroids and antifungals, Standard of care
Assistance Publique - Hôpitaux de Paris
Acute Respiratory Failure, Immunocompromised Patients
09/23
12/23
2017-002867-16: Procollagen-3 driven corticosteroids for persistent Acute Respiratory Distress Syndrome Corticothérapie guidée par le Procollagène-3 dans le Syndrome de Détresse Respiratoire Aiguë persistant.

Not yet recruiting
3
356
Europe
Powder for injection, Methylprdnisolone Mylan 120 mg poudre pour solution injectable (IM-IV), Solumedrol 120mg/2ml lyophilisat et solution pour usage parentéral
Assistance Pubique Hôpitaux de Marseille, Health Ministry (DGOS)
Acute Respiratory Distress Syndrome Syndrome de détresse respiratoire Aigue, Acute Respiratory Distress Syndrome Syndrome de détresse respiratoire Aigue, Diseases [C] - Respiratory Tract Diseases [C08]
 
 
NCT04078568: Efficacy of Immunoglobulin Plus Prednisolone in Reducing Coronary Artery Lesion in Patients With Kawasaki Disease

Recruiting
3
3200
RoW
IVIG, Intravenous Immunoglobulins, Human, Aspirin, Acetylsalicylic acid, Prednisolone, STEROLONE
Children's Hospital of Fudan University, Jiangxi Province Children's Hospital, First People's Hospital of Hangzhou, Shengjing Hospital, The First Hospital of Jilin University, Chengdu Women's and Children's Central Hospital, Children's Hospital of Chongqing Medical University, Inner Mongolia People's Hospital, Sichuan Provincial People's Hospital, Wuhan Union Hospital, China, Third Affiliated Hospital of Zhengzhou University, Children's Hospital of Soochow University, Yuying Children's Hospital of Wenzhou Medical University, Beijing Children's Hospital, Qilu Hospital of Shandong University
Kawasaki Disease
12/24
12/25
NCT04833374: Steroids Therapy in IgA Nephropathy With Crescents

Recruiting
3
200
RoW
Methylprednisolone, Prednisone
Sixth Affiliated Hospital, Sun Yat-sen University
IgA Nephropathy
12/23
12/23
BEAM, NCT05863936: Trial of Belimumab Combined With Multi-target Induction Therapy in Lupus Nephritis

Recruiting
3
15
RoW
Methylprednisolone Injectable Suspension, Methylprednisolone pulse therapy, Belimumab Injection, Beliumab induction therapy, Immunosuppressive Agents, Multi-target immunosuppressive therapy
Nanjing University School of Medicine
Lupus Nephritis, Remission, Safety Issues
03/24
12/24
SEMCORTICO, NCT06266221: Severe Erythema Multiforme - CORTICO

Not yet recruiting
3
96
NA
Prednisone 20 Mg, Oral corticosteriods, Oral Placebo, placebo, Methylprednisolone 120 Mg, IV corticosteriods, IV Placebo
Assistance Publique - Hôpitaux de Paris
Erythema Multiforme
06/27
11/27
NCT06463379: The Efficacy of Intravenous Pulse in Attaining Remission in Refractory Juvenile Idiopathic Arthritis

Recruiting
3
215
RoW
Solumedrol
Sohag University
Refractory Juvenile Idiopathic Arthritis (Despite 2 DMARDs Still Active)
08/24
08/24
NCT06456489: Pulse Steroid Injection in Refractory Rheumatoid Arthritis

Recruiting
3
268
RoW
Solumedrol
Sohag University
Active Rheumatoid Arthritis
09/24
12/24
NCT06532318: Comparative Study Between Platelet Rich Plasma and Steroid Injection in Trigger Finger Treatment

Not yet recruiting
3
40
NA
Platelet rich plasma, Pfizer Depo-medrol
Obafemi Awolowo University Teaching Hospital
Trigger Finger Disorder
12/24
06/25
REGENCY, NCT04221477 / 2019-004034-42: A Study To Evaluate The Efficacy And Safety Of Obinutuzumab In Patients With ISN/RPS 2003 Class III Or IV Lupus Nephritis

Hourglass Oct 2023 - Dec 2023 : From REGENCY trial for lupus nephritis
Active, not recruiting
3
271
Europe, US, RoW
Obinutuzumab, Gazyva, GA101, RO5072759, MMF, Prednisone, Placebo, Methylprednisolone, Acetaminophen, Diphenhydramine
Hoffmann-La Roche
Lupus Nephritis
08/24
02/29
RESPONSE, NCT06635720: REduced-dose Steroid PrOtocol for Childhood Nephrotic SyndromE

Not yet recruiting
3
50
Canada
Prednisone, Prednisolone
The Hospital for Sick Children
Nephrotic Syndrome in Children, Nephrotic Syndrome, Minimal Change, Nephrotic Syndrome, Nephrotic Syndrome，idiopathic
10/25
10/26
I4BiS, NCT02444429 / 2014-005425-13: 3-month Screening Biopsy to Optimize the Immunosuppression in Renal Transplantation

Active, not recruiting
3
346
Europe
Corticosteroid boluses Methylprednisolone, No therapeutic modification, Stop maintenance corticotherapy
Hospices Civils de Lyon
Renal Transplantation
12/24
12/24
NCT04629248: A Study Evaluating the Efficacy and Safety of Obinutuzumab in Participants With Primary Membranous Nephropathy

Active, not recruiting
3
140
Europe, US, RoW
Obinutuzumab, Gazyva, Tacrolimus, Methylprednisolone, Acetaminophen, Diphenhydramine
Hoffmann-La Roche
Primary Membranous Nephropathy
12/25
12/27
ENDURRANCE-1, NCT03942887: Exploring Durable Remission With Rituximab in Antineutrophil Cytoplasmic Antibody(ANCA)-Associated Vasculitis

Recruiting
3
100
Europe
Rituximab, anti-cd20, endoxan, cyclophosphamide, Methylprednisolone, solumedrol, Prednisolone, corticosteroid
Leiden University Medical Center
ANCA Associated Vasculitis
04/25
04/25
PASTA, NCT04873583 / 2021-005571-39: High Dose Steroids in Children With Stroke

Recruiting
3
70
Europe, RoW
Methylprednisolone, Solu-Medrol, Prednisolone, Spiricort
Insel Gruppe AG, University Hospital Bern, University of Bern
Paediatric Stroke
08/25
07/26
EXAFIP2, NCT05674994: Glucocorticoids Versus Placebo for the Treatment of Acute Exacerbation of Idiopathic Pulmonary Fibrosis

Recruiting
3
110
Europe
Methylprednisone/Prednisone, Placebo
Fondation Hôpital Saint-Joseph
Acute Exacerbation of Idiopathic Pulmonary Fibrosis
10/25
12/26
ALLEGORY, NCT04963296 / 2020-005760-57: A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With Systemic Lupus Erythematosus

Active, not recruiting
3
300
Europe, US, RoW
Obinutuzumab, Gazyva, GA101, RO5072759, Placebo, Acetaminophen/Paracetamol, Diphenhydramine hydrochloride, Methylprednisolone
Hoffmann-La Roche
Systemic Lupus Erythematosus
11/25
11/27
THERAMAG, NCT05136976: Rituximab Therapy in Anti-Myelin Associated Glycoprotein Patients With Characteristics of Good Responders

Recruiting
3
90
Europe
Rituximab infusion, Mabthera, Placebo infusion, Sodium chloride (NaCl), Premedications
Centre Hospitalier Universitaire de Saint Etienne, Ministry of Health, France
Anti-MAG Neuropathy
12/25
12/25
STAGO-2, NCT05049603: A Randomized Clinical Trial to Evaluate the Effects of Atorvastatin on Graves' Orbitopathy (GO): the Study

Not yet recruiting
3
102
Europe
Atorvastatin 20mg, Study Group, Placebo, Placebo group
University of Pisa, Università degli Studi dell'Insubria, University of Catania, University of Messina
Graves' Orbitopathy
12/25
12/26
iCaD, NCT05947669: Efficacy and Safety of Infliximab for Immune Checkpoint Inhibitor Induced Colitis

Recruiting
3
195
Europe
Infliximab, Methylprednisolone, Prednisolone
Odense University Hospital, Aalborg University Hospital, Royal Marsden NHS Foundation Trust
Colitis
09/26
09/28
MYTHS-MR, NCT05974462: Trial (MYocarditis THerapy With Steroids in Patients With Mildly Reduced Ejection Fraction)

Recruiting
3
174
Europe
Methylprednisolone 125 MG, Solu-Medrol, IV saline solution 0.9%, sodium chloride
University Hospital, Antwerp, Niguarda Hospital
Acute Myocarditis
10/26
10/28
CORTIFRENCH, NCT03875690: Benefit of a Flash Dose of Corticosteroids in Digestive Surgical Oncology: a Randomized, Double Blind, Placebo-controlled Trial

Active, not recruiting
3
1200
Europe
Injection of methylprednisolone, Injection of sodium chloride, Blood samples
Centre Hospitalier Universitaire Dijon
Elective Surgery for Any Digestive Cancer
02/24
09/27
TAR:GET-1, NCT03994783 / 2018-002882-20: Transplant Antibody-Mediated Rejection: Guiding Effective Treatments

Active, not recruiting
3
3
Europe
Rituximab, Rituximab Biosimilar, Mabthera, Methylprednisolone, Intravenous Immunoglobulin, Plasma Exchange
Imperial College London, Cambridge University Hospitals NHS Foundation Trust, National Institute for Health Research, United Kingdom, Kidney Cancer UK
Kidney Transplant Rejection, Antibody-mediated Rejection
07/27
07/27
REMIT, NCT06120673: REmission in Membranous Nephropathy International Trial

Not yet recruiting
3
224
RoW
Obinutuzumab, Oral prednisolone and cyclophosphamide
The University of Queensland, University of Adelaide
Primary Membranous Nephropathy
01/28
01/28
MYTHS, NCT05150704: - MYocarditis THerapy With Steroids

Recruiting
3
288
Europe, US, RoW
Methylprednisolone, saline solution
Niguarda Hospital, Ministry of Health, Italy, Istituto Di Ricerche Farmacologiche Mario Negri, University of Milano Bicocca, Regione Lombardia
Myocarditis Acute
03/28
12/28
OBILUP, NCT04702256 / 2020-005835-60: Induction Therapy for Lupus Nephritis With no Added Oral Steroids: A Trial Comparing Oral Corticosteroids Plus Mycophenolate Mofetil (MMF) Versus Obinutuzumab and MMF

Recruiting
3
196
Europe
Obinutuzumab administration, GAZYVARO® administration, Administration of Methylprednisolone + Prednisone + Mycophenolate mofetil, Corticosteroid Series, Administration of methylprednisolone, paracetamol and dexchlorpheniramine, Premedication
Assistance Publique - Hôpitaux de Paris, Roche Pharma AG
Lupus Nephritis, Systemic Lupus Erythematosus (SLE)
12/31
12/31
NCT01595048 / 2010-019224-31: Combination Chemotherapy With or Without Rituximab in Treating Younger Patients With Stage III-IV Non-Hodgkin Lymphoma or B-Cell Acute Leukemia

Active, not recruiting
2/3
640
US, Canada, RoW
Rituximab, MOAB IDEC-C2B8, Prednisone, Etoposide, Lastet, Doxorubicin Hydrochloride, Cytarabine, CHX-3311, U-19920, Vincristine Sulfate, Kyocristine, Oncovin, VCR, Vincasar, Cyclophosphamide, Methotrexate, Methylprednisolone, MePRDL, Leucovorin Calcium, CF, Therapeutic Hydrocortisone, Aeroseb-HC, Cetacort, HC, Laboratory Biomarker Analysis
Children's Oncology Group, National Cancer Institute (NCI)
Childhood B Acute Lymphoblastic Leukemia, Childhood Burkitt Leukemia, Childhood Diffuse Large Cell Lymphoma, Mediastinal (Thymic) Large B-Cell Lymphoma, Stage III Childhood Large Cell Lymphoma, Stage IV Childhood Large Cell Lymphoma
12/20
12/20
SOPN, NCT04007328: Sphingosine-1-phosphate and Pneumonia

Recruiting
2/3
400
RoW
Methylprednisolone Sodium Succinate, Placebo
Taipei Medical University WanFang Hospital
Pneumonia, Bacterial
04/21
11/25
MPIV, NCT03876444: Intravenous Methylprednisolone Versus Oral Prednisolone for Infantile Spasms

Recruiting
2/3
128
RoW
Intravenous Methylprednisolone, Oral Pednisolone
Suvasini Sharma
Infantile Spasm
04/22
10/22
NCT05951504: The Prospective Evaluation of Peri-Operative Glucocorticoid Use in the Management of Cervicofacial Infections of Odontogenic Origin

Completed
2/3
29
Canada
Methylprednisolone, Solumedrol
University of Manitoba
Odontogenic Infection of Jaw (Disorder)
03/23
07/23
NCT05752305: Use of Corticosteroids in Third Molar Surgery

Completed
2/3
84
Europe
Dexamethasone 4 Mg/mL Injectable Solution, MethylPREDNISolone 40 Mg/mL Injectable Suspension
Universidad de Granada
Inflammation, Pain, Postoperative, Trismus
07/23
07/23
NCT04942002: Retrobulbar Methylprednisolone as Adjunctive Treatment in Optic Neuritis Trial

Recruiting
2/3
50
RoW
Methylprednisolone Acetate 40 MG/ML [Depo-Medrol], Experimental: Standard treatment + intervention, Placebo Comparator: Standard treatment + placebo, 1. Standard treatment + placebo
Asociación para Evitar la Ceguera en México
Optic Neuritis, Treatment, Methylprednisolone
06/23
09/23
GRAVITAS-309, NCT03584516 / 2018-001606-29: Itacitinib and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease

Calendar Jan 2024 - Dec 2024: Data from GRAVITAS-309 trial for chronic GVHD
Checkmark Discontinued development of itacitinib for GVHD
Aug 2022 - Aug 2022: Discontinued development of itacitinib for GVHD
Checkmark Initiation of GRAVITAS-309 trial for treatment-naive cGVHD
Jan 2019 - Jan 2019: Initiation of GRAVITAS-309 trial for treatment-naive cGVHD
Terminated
2/3
155
Europe, Canada, US, RoW
Itacitinib, INCB039110, Placebo, Methylprednisolone, Medrol, Medrol Dosepak, Solu-Medrol, Prednisone, Deltasone, Prednicot, predniSONE Intensol, Rayos, Sterapred, Sterapred DS
Incyte Corporation
Chronic Graft-versus-host Disease
11/23
11/23
NCT05748561: Effect of Intravenous Methylprednisolone and Intravenous Erythropoietin in Toxic Optic Neuropathies: Randomized Clinical Trial.

Recruiting
2/3
18
RoW
Recombinant human erythropoietin 4,000 UI and 2,000 UI, Experimental Group, Methylprednisolone succinate 500 mg, Control Group
Asociación para Evitar la Ceguera en México
Toxic Optic Neuropathy, Treatment, Methylprednisolone, Erythropoietin
04/24
04/24
IDAR, NCT05545384: Immediate Versus Delayed Treatment With Azathioprine or Rituximab in Anti-MOG Antibodies Associated Acute Demyelinating Syndromes in Children: a Randomized Controlled Clinical Trial

Not yet recruiting
2/3
86
Europe
Immediate Azathioprine (1st attack), Immediate Rituximab (1st attack), Standard of care
Assistance Publique - Hôpitaux de Paris, Institut National de la Santé Et de la Recherche Médicale, France
Acute Demyelinating Syndrome
01/26
08/29
NCT04046549: A Study to Evaluate the Safety and Efficacy of Dual Costimulation Blockade With VIB4920 and Belatacept for Prophylaxis of Allograft Rejection in Adults Receiving a Kidney Transplant

Completed
2a
25
US
Belatacept, VIB4920, Thymoglobulin, Methylprednisolone
Viela Bio (acquired by Horizon Therapeutics)
Allografts, Rejection; Transplant, Kidney, Transplant Rejection, Kidney Transplantation
07/22
03/23
ACTRN12622000530729: Autologous Stem Cell Transplant in other Neuro-Inflammatory diseases

Not yet recruiting
2
20
 
St Vincent's Hospital, Sydney , St Vincent's Hospital,Sydney
Neuromyelitis Optica, Stiff Person Syndrome, Myasthenia Gravis, Central Nervous System Vasculitis
 
 
ACTRN12619000348156: Autologous Haematopoietic Stem Cell Transplantation for highly active treatment resistant multiple sclerosis.

Recruiting
2
50
 
Alfred Health, Alfred Health
Relapsing Remitting Multiple Sclerosis
 
 
ACTRN12616000151437: A Phase II study: Haematopoietic Stem Cell Transplantation for highly active treatment resistant multiple sclerosis .

Recruiting
2
20
 
Austin Health, Austin Health
Relapsing Remitting Multiple Sclerosis
 
 
ACTRN12622000536763: Autologous Stem Cell Transplant in Multiple Sclerosis

Recruiting
2
30
 
St Vincent's Hospital, Sydney , St Vincent's Hospital,Sydney
Multiple Sclerosis
 
 
2005-005733-35: Invloed van corticoïden op de nierfunctie postoperatief na cardiochirurgie

Ongoing
2
80
Europe
methylprednisolon, Powder for solution for injection, Solu-Medrol
University Hospital Ghent
Patiënten met cardiale pathologie (klep en/of coronair)
 
 
 

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