methylprednisolone sodium succinate / Generic mfg.  >>  Phase 2
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143 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
methylprednisolone sodium succinate / Generic mfg.
MetCOVID, NCT04343729: Methylprednisolone in the Treatment of Patients With Signs of Severe Acute Respiratory Syndrome in Covid-19

Completed
2b
416
RoW
Methylprednisolone Sodium Succinate, methylprednisolone, Placebo solution, placebo
Fundação de Medicina Tropical Dr. Heitor Vieira Dourado
SARS-CoV Infection, Severe Acute Respiratory Syndrome (SARS) Pneumonia
06/20
10/20
NCT02462252: Phase IIA Open Label Study to Evaluate Efficacy and Safety of BL-8040 Followed by (hATG), Cyclosporine and Methyprednisolone in Adult Subjects With Aplastic Anemia or Hypoplastic Myelodysplastic Syndrome

Completed
2a
11
US
BL-8040, horse anti-thymocyte globulin (hATG), ATGAM, Methylprednisolone, Medrol, Solu-Medrol, Depo-Medrol, Cyclosporine, Sandimmune, Cyclosporine A
BioLineRx, Ltd.
Aplastic Anemia, Hypoplastic Myelodysplastic Syndrome
11/20
11/20
NCT04046549: A Study to Evaluate the Safety and Efficacy of Dual Costimulation Blockade With VIB4920 and Belatacept for Prophylaxis of Allograft Rejection in Adults Receiving a Kidney Transplant

Completed
2a
25
US
Belatacept, VIB4920, Thymoglobulin, Methylprednisolone
Viela Bio (acquired by Horizon Therapeutics)
Allografts, Rejection; Transplant, Kidney, Transplant Rejection, Kidney Transplantation
07/22
03/23
ACTRN12622000530729: Autologous Stem Cell Transplant in other Neuro-Inflammatory diseases

Not yet recruiting
2
20
 
St Vincent's Hospital, Sydney , St Vincent's Hospital,Sydney
Neuromyelitis Optica, Stiff Person Syndrome, Myasthenia Gravis, Central Nervous System Vasculitis
 
 
ACTRN12619000348156: Autologous Haematopoietic Stem Cell Transplantation for highly active treatment resistant multiple sclerosis.

Recruiting
2
50
 
Alfred Health, Alfred Health
Relapsing Remitting Multiple Sclerosis
 
 
ACTRN12609000602224: Erythropoietin plus methylprednisolone versus methylprednisolone plus placebo in the treatment of acute spinal cord injury: A pilot study

Completed
2
30
 
Shiraz University of Medical Sciences, Pooyesh Darou
Acute spinal cord injury
 
 
ACTRN12616000151437: A Phase II study: Haematopoietic Stem Cell Transplantation for highly active treatment resistant multiple sclerosis .

Recruiting
2
20
 
Austin Health, Austin Health
Relapsing Remitting Multiple Sclerosis
 
 
ACTRN12622000536763: Autologous Stem Cell Transplant in Multiple Sclerosis

Recruiting
2
30
 
St Vincent's Hospital, Sydney , St Vincent's Hospital,Sydney
Multiple Sclerosis
 
 
NCT01177371: High-Dose Busulfan and High-Dose Cyclophosphamide Followed By Donor Bone Marrow Transplant in Treating Patients With Leukemia, Myelodysplastic Syndrome, Multiple Myeloma, or Recurrent Hodgkin or Non-Hodgkin Lymphoma

Completed
2
13
US
busulfan, BSF, BU, Misulfan, Mitosan, Myeloleukon, Myelosan, cyclophosphamide, CPM, CTX, Cytoxan, Endoxan, Endoxana, Enduxan, allogeneic bone marrow transplantation, bone marrow therapy, allogeneic, bone marrow therapy, allogenic, transplantation, allogeneic bone marrow, transplantation, allogenic bone marrow, methylprednisolone, A-MethaPred, Depo-Medrol, Medrol, MePRDL, Solu-Medrol, Wyacort, methotrexate, Abitrexate, amethopterin, Folex, methylaminopterin, Mexate, MTX, cyclosporine, 27-400, ciclosporin, cyclosporin, cyclosporin A, CYSP, Sandimmune
Case Comprehensive Cancer Center
Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Monoblastic Leukemia (M5a), Adult Acute Monocytic Leukemia (M5b), Adult Acute Myeloblastic Leukemia With Maturation (M2), Adult Acute Myeloblastic Leukemia Without Maturation (M1), Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With T(15;17)(q22;q12), Adult Acute Myeloid Leukemia With T(16;16)(p13;q22), Adult Acute Myeloid Leukemia With T(8;21)(q22;q22), Adult Acute Myelomonocytic Leukemia (M4), Adult Acute Promyelocytic Leukemia (M3), Adult Erythroleukemia (M6a), Adult Nasal Type Extranodal NK/T-cell Lymphoma, Adult Pure Erythroid Leukemia (M6b), Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, Burkitt Lymphoma, Childhood Acute Erythroleukemia (M6), Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Megakaryocytic Leukemia (M7), Childhood Acute Monoblastic Leukemia (M5a), Childhood Acute Monocytic Leukemia (M5b), Childhood Acute Myeloblastic Leukemia With Maturation (M2), Childhood Acute Myeloblastic Leukemia Without Maturation (M1), Childhood Acute Myeloid Leukemia in Remission, Childhood Acute Myelomonocytic Leukemia (M4), Childhood Acute Promyelocytic Leukemia (M3), Childhood Chronic Myelogenous Leukemia, Childhood Myelodysplastic Syndromes, Chronic Phase Chronic Myelogenous Leukemia, Cutaneous B-cell Non-Hodgkin Lymphoma, De Novo Myelodysplastic Syndromes, Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue, Hepatosplenic T-cell Lymphoma, Intraocular Lymphoma, Nodal Marginal Zone B-cell Lymphoma, Peripheral T-Cell Lymphoma, Post-transplant Lymphoproliferative Disorder, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Adult Non-Hodgkin Lymphoma, Recurrent Adult T-cell Leukemia/Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Small Lymphocytic Lymphoma, Refractory Multiple Myeloma, Relapsing Chronic Myelogenous Leukemia, Secondary Myelodysplastic Syndromes, Small Intestine Lymphoma, Splenic Marginal Zone Lymphoma, Testicular Lymphoma, Waldenstrom Macroglobulinemia
02/00
02/10
NCT00004192: Colony-Stimulating Factors to Relieve Neutropenia in Patients With Recurrent Non-Hodgkin's Lymphoma

Completed
2
60
US
filgrastim, Neupogen, pegfilgrastim, Neulasta, cisplatin, chemotherapy drug, cytarabine, cytosine arabinoside, etoposide, Etopophos, Toposar, methylprednisolone, Depo-Medrol, Medrol, Solu-Medrol, P-Care D80, ReadySharp Methylprednisolone, and P-Care D40
University of Nebraska, National Cancer Institute (NCI)
Lymphoma, Neutropenia
02/01
03/01
NCT00002941: Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With Recurrent or Refractory Hodgkin's or Non-Hodgkin's Lymphoma

Completed
2
69
US, Canada, Europe, RoW
carmustine, BCNU, NSC-409962, cyclophosphamide, Cytoxan, NSC-26271, etoposide, VP-16, VePesid, NSC-141540, mesna, Mesnex, NSC-113891, peripheral blood stem cell transplantation
Children's Oncology Group, National Cancer Institute (NCI)
Lymphoma
11/02
03/07
NCT00109993: Campath-1H + FK506 and Methylprednisolone for GVHD

Completed
2
34
US
alemtuzumab, methylprednisolone, tacrolimus
Case Comprehensive Cancer Center, National Cancer Institute (NCI)
Breast Cancer, Chronic Myeloproliferative Disorders, Gestational Trophoblastic Tumor, Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases, Neuroblastoma, Ovarian Cancer, Testicular Germ Cell Tumor
06/06
05/07
NCT00136903: Safety and Efficacy Study of Adult Human Mesenchymal Stem Cells to Treat Acute Graft Versus Host Disease (GVHD)

Completed
2
32
US
Prochymal® - 2 Million cells/kg, Remestemcel-L, ex-vivo cultured adult human mesenchymal stem cells, hMSCs, Prochymal®- 8 Million cells/kg, Methylprednisolone, Prednisone, Cyclosporine, Tacrolimus, Mycophenolate Mofetil
Mesoblast, Inc.
Graft Vs Host Disease
07/06
07/08
NCT00141713: The Use of Etanercept (Enbrel®) in the Treatment of Acute Graft-Versus-Host Disease

Completed
2
40
US
Etanercept
University of Michigan Rogel Cancer Center
Graft-Versus-Host Disease
11/06
12/06
2005-005733-35: Invloed van corticoïden op de nierfunctie postoperatief na cardiochirurgie

Ongoing
2
80
Europe
methylprednisolon, Powder for solution for injection, Solu-Medrol
University Hospital Ghent
Patiënten met cardiale pathologie (klep en/of coronair)
 
 
NCT00411879: Combined Vasopressin, Methylprednisolone, and Epinephrine for Inhospital Cardiac Arrest

Completed
2
100
Europe
Vasopressin, Epinephrine, and Steroids, Placebo, Epinephrine, Placebo
University of Athens
Heart Arrest
04/07
04/07
NCT00003335: Umbilical Cord Blood Transplantation in Treating Patients With High-Risk Hematologic Cancer

Completed
2
44
US
anti-thymocyte globulin, busulfan, cyclosporine, melphalan, methylprednisolone, umbilical cord blood transplantation, radiation therapy
Case Comprehensive Cancer Center, National Cancer Institute (NCI)
Graft Versus Host Disease, Leukemia, Lymphoma, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases
11/07
01/12
SIERRA, NCT00282308: A Study to Evaluate the Effects of Rituximab on Immune Responses in Subjects With Active Rheumatoid Arthritis Receiving Background Methotrexate

Completed
2
103
US
Rituximab, Rituxan, MabThera, Methotrexate, Methylprednisone, C. albicans, Tetanus toxoid adsorbed booster vaccine, 23-valent pneumococcal polysaccharide vaccine, Keyhole limpet hemocyanin
Genentech, Inc.
Rheumatoid Arthritis
01/08
05/12
NCT00241982: Long-Circulating Liposomal Prednisolone Versus Pulse Intramuscular Methylprednisolone in Patients With Active Rheumatoid Arthritis

Completed
2
22
Europe
long-circulating liposomal prednisolone
Radboud University Medical Center, Utrecht University
Rheumatoid Arthritis
03/08
05/08
NCT00555542: An Analysis of Peripheral Blood T Cell Subsets on Rheumatoid Arthritis

Completed
2
10
RoW
rituximab, Mabthera
Chinese University of Hong Kong
Rheumatoid Arthritis
05/08
05/08
NCT00354172: Donor Umbilical Cord Blood Natural Killer Cells, Aldesleukin and Umbilical Cord Blood Transplant in Patients With Refractory Hematologic Cancers.

Terminated
2
16
US
aldesleukin, IL-2, interleukin-2, filgrastim, granulocyte colony-stimulating factor (G-CSF), natural killer cell (NK) therapy, NK cells, cyclophosphamide, Cytoxan, cyclosporine, cyclosporin, fludarabine phosphate, Fludara, methylprednisolone, Medrol, Solu-Medrol, Depo-Medrol, methylprednisolone sodium succinate, mycophenolate mofetil, mycophenolic acid, Umbilical Cord Blood Transplantation (UCBT), allogeneic transplant, Total body irradiation (TBI), radiation
Masonic Cancer Center, University of Minnesota
Leukemia, Myelodysplastic Syndromes
08/08
08/08
RUMBA, NCT00243412: A Study of the Safety and Efficacy of Rituximab in Patients With Moderate to Severe Rheumatoid Arthritis Receiving Methotrexate

Completed
2
42
US
folate, methotrexate, methylprednisolone, Placebo, Rituximab
Genentech, Inc.
Rheumatoid Arthritis
02/09
02/09
NCT00298272: Safety and Tolerability of Rituxan With Methotrexate and Etanercept or Methotrexate and Adalimumab in Patients With Active Rheumatoid Arthritis

Terminated
2
54
US
IDEC-C2B8 (rituximab), Rituxan, Placebo, Methotrexate, Etanercept, Enbrel, Adalimumab, Humira, Methylprednisolone, Folate
Biogen, Hoffmann-La Roche, Genentech, Inc.
Rheumatoid Arthritis
04/09
07/11
NCT01423864: Intrapleural Methylprednisolone Injection for Multiple Organ Failure With Acute Respiratory Distress Syndrome

Completed
2
29
RoW
conventional ECMO with intravenous steroid, Solu-Cortef, solumedrol
National Taiwan University Hospital
Acute Respiratory Distress Syndrome (ARDS), Multiple Organ Failure
06/09
06/09
NCT00066469: Cyclophosphamide, Rituximab, and Either Prednisone or Methylprednisolone in Treating Patients With Lymphoproliferative Disease After Solid Organ Transplantation

Checkmark P2 data
Aug 2012 - Aug 2012: P2 data
Completed
2
55
Canada, US, RoW
rituximab, IDEC-C2B8, NSC #687451, cyclophosphamide, Cytoxan, NSC #26271, methylprednisolone, Deltaone, Meticorten, Orasone, Liquid Pred, Pediapred, Sterapred, NSC #010023, prednisone
Children's Oncology Group, National Cancer Institute (NCI)
Lymphoproliferative Disorder
10/09
12/13
NCT00423098 / 2006-002107-13: Efficacy and Safety of Enteric-coated Mycophenolate Sodium in Combination With Two Corticosteroid Regimens for the Treatment of Lupus Nephritis Flare

Completed
2
81
Europe, RoW
Mycophenolate sodium, Myfortic, Prednisone, Methylprednisolone
Novartis Pharmaceuticals
Lupus Nephritis
11/09
11/09
NCT00556192: Can Targeted Elimination of B-cell Depletion Therapy and/or Combination Therapy on Systemic Lupus Erythematosus

Completed
2
20
RoW
rituximab, Mabthera
Chinese University of Hong Kong
Systemic Lupus Erythematosus
12/09
12/09
NCT00550342: Rituximab Treatment of Focal Segmental Glomerulosclerosis

Completed
2
10
US
rituximab, Rituxan
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Genentech, Inc., Indiana University
Focal Segmental Glomerulosclerosis (FSGS)
12/09
12/09
NCT00482053: Phase 2 Poor Risk DLBCL of TLI and ATG Followed by Matched Allogeneic HT as Consolidation to Autologous HCT

Terminated
2
3
US
Autologous hematopoietic stem cell transplantation (auto-HSCT), Autologous peripheral blood progenitor cell (PBPC) transplantation, Allogeneic hematopoietic stem cell transplantation (allo-HSCT), Allogeneic peripheral blood progenitor cell (PBPC) transplantation, Total lymphoid irradiation (TLI), Rituximab, Rituxan, Mabthera, Carmustine, BCNU, BiCNU, Etoposide, Eposin, Etopophos, Vepesid, VP-16, Filgrastim, Granulocyte colony-stimulating factor (G-CSF, GCSF), Colony-stimulating factor 3 (CSF-3), Anti-thymocyte globulin (ATG), Cyclosporine, Cyclosporin, CSP, Mycophenolate mofetil (MMF), CellCept, Cyclophosphamide, Cytoxan, Neosar, Acetaminophen, Tylenol, Diphenhydramine, Benadryl, Hydrocortisone, Cortef, Methylprednisolone, Solu-Medrol
Stanford University
Lymphoma, B-cell, Lymphoma, Non-Hodgkin, Diffuse Large B-cell Lymphoma (DLBCL), Malignant Lymphoma, Non-Hodgkin
05/10
05/10
NCT00186628: Phase 2 Trial of Prophylactic Rituximab Therapy for Prevention of CGVHD

Completed
2
36
US
Total lymphoid irradiation, TLI, Rituximab, Rituxan, Anti-thymoglobulin, rabbit (ATG, rabbit ATG), Cyclosporine, CSP, Sandimmune, Mycophenylate mofetil, MMF, CellCept, Filgrastim, G-CSF, Granulocyte-colony stimulating factor, Neupogen, Granisetron, Sancuso, Solumedrol, Medrol, Depo-Medrol, A-Methapred, Acetaminophen, Tylenol, Diphenhydramine, Benadryl, Hydrocortisone, Westcort
Stanford University, The Leukemia and Lymphoma Society, National Cancer Institute (NCI)
Leukemia, Mast-Cell, Mantle-cell Lymphoma
11/10
12/10
NCT00185692: Allogeneic Transplantation From Related Haploidentical Donors

Completed
2
16
US
non-myeloablative hematopoietic cell transplantation, Peripheral-blood stem-cell transplantation, Anti-Thymocyte Globulin, ATG, Cyclosporine, INN/BAN, USAN, CSA, Mycophenolate Mofetil, MMF, CellCept, G-CSF, Granulocyte colony-stimulating factor, CSF 3, Solumedrol, 6-Methylprednisolone, Methylprednisolone Acetate, Methylprednisolone Sodium Succinate, Acetaminophen, Tylenol, Diphenydramine, Benadryl, Allermax, Q-Dryl, Diphen Cough, Hydrocortisone, Hydrocortisone Sodium Phosphate
Stanford University
Blood Cancer, Leukemia, Graft Versus Host Disease, Malignancy, CLL, NHL, Hodgkin's Disease, MDS
12/10
12/10
NCT00128180: Efficacy of Methylprednisolone for Hantavirus Cardiopulmonary Syndrome

Completed
2
66
RoW
Methylprednisolone, Medrol, Placebo
University of New Mexico, National Institute of Allergy and Infectious Diseases (NIAID)
Hantavirus Infections
12/10
10/11
2010-023560-40: Blood stem cell transplantation for patients with relapsiong-remitting multiple sclerosis, in whom standard treatment has failed. Blodstamcellstransplantation för patienter med skovvis förlöpande MS (multipel sklerosis), där standardbehandling givit otillräcklig effekt.

Ongoing
2
120
Europe
, Powder for solution for injection, Powder for infusion*, Solution for injection, Powder and solvent for dispersion for injection, Tysabri, Sendoxan, Thymoglobuline, Neupogen, Solu-Medrol
Uppsala l�ns landsting
Relapsing-remitting multiple sclerosis
 
 
NCT01039103 / 2009-013884-21: Nanocort in Acute Exacerbation of Relapsing-Remitting Multiple Sclerosis (MS)

Terminated
2
15
Europe
PEG-liposomal prednisolone sodium phosphate, Nanocort, Methylprednisolone, Solu-Medrol
Galapagos NV
Acute Exacerbation of Remitting Relapsing Multiple Sclerosis, Clinically Isolated Syndrome
11/11
11/11
RESTORE, NCT01071083 / 2009-017490-38: Treatment Interruption of Natalizumab

Checkmark Interim Data AAN (MS)
Mar 2012 - Mar 2012: Interim Data AAN (MS)
Completed
2
175
US, Europe
natalizumab, interferon beta 1-a, methylprednisolone, IV placebo, glatiramer acetate
Biogen, Elan Pharmaceuticals
Relapsing Remitting Multiple Sclerosis
11/11
11/11
NCT00806598: Thymoglobulin and Cyclosporine in Patients With Aplastic Anemia or Myelodysplastic Syndrome

Completed
2
53
US
Thymoglobulin, ATG, Antithymocyte globulin, Cyclosporine, CYA, Sandimmune, Cyclosporine A, Methylprednisolone, Duralone®, Medralone®, Medrol®, M-Prednisol®, Solu-Medrol®, G-CSF, Neupogen®, Granulocyte - Colony Stimulating Factor
M.D. Anderson Cancer Center, Genzyme, a Sanofi Company
Myelodysplastic Syndrome, Aplastic Anemia
06/12
06/12
NCT00109928: S0350 Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Peripheral T-Cell Non-Hodgkin's Lymphoma

Completed
2
34
US
cisplatin, etoposide, gemcitabine, methylprednisolone
Southwest Oncology Group, National Cancer Institute (NCI)
Lymphoma
06/12
04/14
NCT00248534: Rituximab, Temozolomide, and Methylprednisolone in Treating Patients With Recurrent Primary CNS Non-Hodgkin's Lymphoma

Terminated
2
16
US
rituximab, methylprednisolone, temozolomide, TMZ
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, National Cancer Institute (NCI)
Lymphoma
09/12
09/12
2012-003213-34: Methylprednisolone and N- aceltylcisteine in hepatic resections Metilprednisolone e N-acetilcisteina nelle resezioni epatiche

Ongoing
2
150
Europe
Powder and solvent for solution for injection, Solution for injection, SOLUMEDROL*IM IV FL 500MG+F8ML, ACETILCISTEINA*EV NEB 5F 300MG
ISTITUTO CLINICO HUMANITAS, Istituto Clinico Humanitas
patients candidate to liver resection candidati intervento chirurgico di resezione epatica, patients candidate to liver resection candidati intervento chirurgico di resezione epatica, Diseases [C] - Cancer [C04]
 
 
NCT00084695: Umbilical Cord Blood for Stem Cell Transplantation in Treating Young Patients With Malignant or Nonmalignant Diseases

Unknown status
2
25
US
anti-thymocyte globulin, busulfan, cyclophosphamide, fludarabine phosphate, melphalan, methylprednisolone, radiation therapy
Milton S. Hershey Medical Center
Childhood Langerhans Cell Histiocytosis, Fanconi Anemia, Leukemia, Lymphoma, Myelodysplastic Syndromes, Neuroblastoma, Sarcoma, Unspecified Childhood Solid Tumor, Protocol Specific
12/12
 
ENZON-OHSU-4913, NCT01005914: Pegaspargase and Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Terminated
2
11
US
cyclophosphamide, Cytoxan, Neosar, CTX, cytarabine, Cytosar-U, Ara-C, Arabinosylcytosine, dexamethasone, Decadron, DexPak, dex, doxorubicin hydrochloride, Adriamycin RDF, Adriamycin PFS, imatinib mesylate, Gleevec, Glivec, methotrexate, Trexall, Rheumatrex, MTX, methylprednisolone, Medrol, Depo-Medrol, Solu-Medrol, pegaspargase, Onscapar, PEG-L-asparaginase, vincristine sulfate, Marqibo
OHSU Knight Cancer Institute
Leukemia
03/13
05/14
METALL, NCT01790022: Efficacy and Safety of MEthylprednisolone Administered Intravenously for the Treatment of Patients With Active AnkyLosing spondyLitis

Unknown status
2
20
RoW
Methylprednisolone, Metypred, Medrol, Solu-Medrol
Saratov State Medical University, Charite University, Berlin, Germany
Ankylosing Spondylitis
03/13
 
NCT00671658: Modified Hyper-CVAD (Cyclophosphamide, Vincristine, Adriamycin, and Dexamethasone) Program for Acute Lymphoblastic Leukemia

Completed
2
220
US
Rituximab, Rituxan, Cyclophosphamide (CTX), Cytoxan, Neosar, Doxorubicin, Adriamycin, Rubex, Vincristine, Oncovin, Vincasar Pfs, Dexamethasone, Decadron, Methotrexate (MTX), Rheumatrex, Cytarabine, Ara-C, Cytosar-U, Arabinosylcytosine, DepoCyt, G-CSF, Filgrastim, Neupogen, Mesna, Mesnex, Pegylated asparaginase, Pegaspargase, Oncaspar, Polyethylene Glycol Conjucated Lasparaginase-H, Pegfilgrastim, Neulasta, PEG-G-CSF, Solumedrol, Methylprednisolone, Depo-Medrol, Medrol
M.D. Anderson Cancer Center
Leukemia, Acute Lymphoblastic Leukemia
07/13
07/13
NCT00899847: Phase 2 Study of Autologous Followed by Nonmyeloablative Allogeneic Transplantation Using TLI & ATG

Completed
2
9
US
Autologous peripheral blood stem cells (auto-PBSC) transplantation, auto-PBPC, Autologous peripheral blood progenitor cells (auto-PBPC) transplantation, Allogeneic peripheral blood stem cells (allo-PBSC) transplantation, allo-PBSC, Allogeneic peripheral blood progenitor cells (allo-PBPC) transplantation, Filgrastim, Neupogen, Granulocyte colony-stimulating factor (G-CSF), r-metHuG-CSF, Cyclophosphamide, Ciclofosfamida, Ciclofosfamide, Claphene, CP monohydrate (CPM), CSP, Melphalan, L-Sarcolysin, L-phenylalanine mustard (L-PAM), L-Sarcolysin phenylalanine mustard, L-sarcolysine, Cyclosporine, Cyclosporin, Cyclosporin A, Ciclosporin, Total lymphoid irradiation, TLI, Rabbit anti-thymocyte globulin, Thymoglobulin, ATG, Mycophenolate Mofetil 250mg, CellCept, MMF, Solumedrol, Solumedin, Soludecadron, Diphenhydramine, Benadryl, Acetaminophen, Tylenol, Hydrocortisone
Stanford University
Transplantation, Homologous, Transplantation, Autologous, Multiple Myeloma, Blood and Marrow Transplant (BMT)
04/14
12/14
NCT00481832: Autologous Followed by Non-myeloablative Allogeneic Transplantation for Non-Hodgkin's Lymphoma

Terminated
2
50
US
Cyclophosphamide, Cytoxan, Neosar, BCNU, BiCNU, Carmustine, Etoposide, Eposin, Etopophos, VP-16, Filgrastim, Granulocyte colony-stimulating factor (G-CSF, GCSF), Colony-stimulating factor (CSF) 3, Antithymocyte globulin, ATG, Cyclosporine, cyclosporin, cyclosporin A, Mycophenolate mofetil, MMF, CellCep, Rituximab, Rituxan, MabThera, Autologous hematopoietic stem cell transplantation (auto-HSCT), Autologous peripheral blood progenitor cell (PBPC) transplantation, Allogeneic hematopoietic stem cell transplantation (allo-HSCT), Allogeneic peripheral blood progenitor cell (PBPC) transplantation, Total lymphoid irradiation, TLI, CD34+ Cells, Solu-Medrol, Methylprednisolone
Stanford University
Lymphoma, Non-Hodgkin
10/14
03/17
DARA-GEN501, NCT00574288 / 2007-003783-22: Daratumumab (HuMax®-CD38) Safety Study in Multiple Myeloma

Checkmark From GEN501 and SIRIUS trials for MM at ASH 2017 [screenshot]
Dec 2017 - Dec 2017: From GEN501 and SIRIUS trials for MM at ASH 2017 [screenshot]
Checkmark From SIRIUS and GEN501 trials in multiple myeloma at EHA 2016
Jul 2016 - Jul 2016: From SIRIUS and GEN501 trials in multiple myeloma at EHA 2016
Checkmark MM
More
Completed
2
104
US, Europe
Part 1: Daratumumab, HuMax-CD38, Part 2: Daratumumab, Methylprednisolone, Dexamethasone
Janssen Research & Development, LLC
Multiple Myeloma
01/15
04/17
NCT01621880: Effect of Bevacizumab on Radiation-induced Brain Necrosis in Patients With Nasopharyngeal Carcinoma

Completed
2
112
RoW
bevacizumab, Bevacizumab（Avastin）, Corticosteroid, methylprednisolone
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Nasopharyngeal Carcinoma, Adverse Effect of Radiation Therapy, Brain Necrosis
08/15
12/15
2015-002127-26: Comparison between treatment with belimumab and methylprednisolone in Graves’hyperthyroidism (GD) and active orbitopathy (GO). Confronto tra terapia dell’ipertiroidismo di Graves’ (GD) ed orbitopatia basedowiana (GO) attiva con belimumab vs metilprednisolone

Ongoing
2
40
Europe
BENLYSTA, SOLU MEDROL, L04AA26, D07AA01, Powder and solvent for solution for injection, BENLYSTA - 120 MG - POLVERE PER CONCENTRATO PER SOLUZIONE PER INFUSIONE - USO ENDOVENOSO - FLACONCINO (VETRO) 120 MG 1 FLACONCINO, SOLU MEDROL - 500 MG/8 ML POLVERE E SOLVENTE PER SOLUZIONE INIETTABILE 1 FLACONE DI POLVERE DA 500 MG+ FIALA SOLVENTE DA 8 ML
FONDAZIONE IRCCS CA' GRANDA OSPEDALE MAGGIORE POLICLINICO, Glaxo Smith&Kline GSK International
GRAVES' ORBITOPATHY ORBITOPATIA BASEDOWIANA, GRAVES' ORBITOPATHY ORBITOPATIA BASEDOWIANA, Diseases [C] - Hormonal diseases [C19]
 
 
NCT01093586: Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Completed
2
14
US
double-unit umbilical cord blood transplantation, cytogenetic analysis, bone marrow aspiration, fluorescence in situ hybridization, fluorescence in situ hybridization (FISH), busulfan, BSF, BU, Misulfan, Mitosan, Myeloleukon, Myelosan, cyclophosphamide, CPM, CTX, Cytoxan, Endoxan, Endoxana, Enduxan, anti-thymocyte globulin, ATG, ATGAM, lymphocyte immune globulin, Thymoglobulin, methylprednisolone, A-MethaPred, Depo-Medrol, Medrol, MePRDL, Solu-Medrol, Wyacort, cyclosporine, 27-400, ciclosporin, cyclosporin, cyclosporin A, CYSP, Sandimmune, mycophenolate mofetil, Cellcept, MMF, flow cytometry, allogeneic hematopoietic stem cell transplantation
Case Comprehensive Cancer Center
Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0), Adult Acute Monoblastic Leukemia (M5a), Adult Acute Monocytic Leukemia (M5b), Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Erythroleukemia (M6a), Adult Nasal Type Extranodal NK/T-cell Lymphoma, Adult Pure Erythroid Leukemia (M6b), B-cell Adult Acute Lymphoblastic Leukemia, B-cell Childhood Acute Lymphoblastic Leukemia, Blastic Phase Chronic Myelogenous Leukemia, Burkitt Lymphoma, Childhood Acute Erythroleukemia (M6), Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Megakaryocytic Leukemia (M7), Childhood Acute Minimally Differentiated Myeloid Leukemia (M0), Childhood Acute Monoblastic Leukemia (M5a), Childhood Acute Monocytic Leukemia (M5b), Childhood Acute Myeloid Leukemia in Remission, Childhood Chronic Myelogenous Leukemia, Childhood Diffuse Large Cell Lymphoma, Childhood Immunoblastic Large Cell Lymphoma, Childhood Myelodysplastic Syndromes, Childhood Nasal Type Extranodal NK/T-cell Lymphoma, Chronic Myelomonocytic Leukemia, Chronic Phase Chronic Myelogenous Leukemia, Cutaneous B-cell Non-Hodgkin Lymphoma, de Novo Myelodysplastic Syndromes, Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue, Juvenile Myelomonocytic Leukemia, Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Nodal Marginal Zone B-cell Lymphoma, Previously Treated Myelodysplastic Syndromes, Prolymphocytic Leukemia, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Anaplastic Large Cell Lymphoma, Recurrent Childhood Grade III Lymphomatoid Granulomatosis, Recurrent Childhood Large Cell Lymphoma, Recurrent Childhood Lymphoblastic Lymphoma, Recurrent Childhood Small Noncleaved Cell Lymphoma, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Small Lymphocytic Lymphoma, Refractory Chronic Lymphocytic Leukemia, Relapsing Chronic Myelogenous Leukemia, Secondary Acute Myeloid Leukemia, Secondary Myelodysplastic Syndromes, Secondary Myelofibrosis, Splenic Marginal Zone Lymphoma, Stage I Chronic Lymphocytic Leukemia, Stage II Chronic Lymphocytic Leukemia, Stage III Chronic Lymphocytic Leukemia, Stage IV Chronic Lymphocytic Leukemia, T-cell Adult Acute Lymphoblastic Leukemia, T-cell Childhood Acute Lymphoblastic Leukemia, T-cell Large Granular Lymphocyte Leukemia, Waldenstrom Macroglobulinemia
12/15
12/15
BOMP, NCT01612988: Treatment With Bendamustine, Ofatumumab and MethylPrednisolone in Relapsed B-CLL

Checkmark EHA 2014
May 2014 - May 2014: EHA 2014
Checkmark ASH 2013
Nov 2013 - Nov 2013: ASH 2013
Checkmark ASH 2013
More
Terminated
2
74
Europe
BOMP
French Innovative Leukemia Organisation
B-cell Chronic Lymphocytic Leukemia (B-CLL)
12/15
04/18
2005-004180-28: Kan en enkelt dosis steroid nedsætte mængeden af serom efter mastektomi? et randomiseret pilotstudie

Ongoing
2
40
Europe
solu-medrol, Solu-Medrol, Solu-Medrol
Brystkirurgisk afd. F Amtsygehuset i Herlev 18 sal
Seromdannelse efter mastektomi
 
 
2005-005692-15: Evaluation of bio-clinician plus of perisurgery administration of Metilprednisolone MP in high doses in short term in laparotomy and laparoscopic colic surgeryfor neoplastic patology. Prospective, controlled double blind, randomized study.

Completed
2
104
Europe
SOLU-MEDROL IM IV1FL1ML40MG, SOLU-MEDROL IM IV1FL1ML40MG
OSPEDALE S. RAFFAELE
patients undergoing to laproscopic and laparotomic colic surgery
 
 
2007-000699-18: Randomized phase II study of two associations of rituximab and chemotherapy, with a pet-driven strategy, in patients from 18 to 59 with DLBCL CD20+ lymphoma and 2 or 3 adverse prognostic factors of the age-adjusted IPI

Ongoing
2
222
Europe
PREDNISONE, RITUXIMAB, DOXORUBICINE, CYCLOPHOSPHAMIDE, VINDESINE, BLEOMYCIN, METHOTREXATE, G-CSF, VINCRISTINE, IFOSFAMIDE, ETOPOSIDE, CYTARABINE, CARMUSTINE, MELPHALAN, autologous stem cells, Solu-Medrol®, Medrol®, Mabthera 100mg, Mabthera 500mg, ADRIBLASTINA®, ENDOXAN®, BLEOMYCINE®, LEDERTREXATE®, Neupogen®, VINCRISIN®, VEPESID®, HOLOXAN®, Cytosar®, Alkeran®, VORINA®, NITRUMON®, ZEVALIN, Solu-Medrol®, Medrol®, Mabthera 100mg, Mabthera 500mg, ADRIBLASTINA®, ENDOXAN®, BLEOMYCINE®, LEDERTREXATE®, Neupogen®, VINCRISIN®, VEPESID®, HOLOXAN®, Cytosar®, Alkeran®, VORINA®, NITRUMON®, ZEVALIN
Hospices Civils de Lyon, Groupe d\'Etude des Lymphomes de l\'Adulte(GELA)
CD20+ diffuse large B-cell lymphoma
 
 
NCT01884571: Immunosuppression in Amyotrophic Lateral Sclerosis (ALS)

Completed
2
31
US
Basiliximab, Simulect, Methylprednisolone, Solumedrol, Prednisone, Deltasone, Orasone, Tacrolimus, Prograf, Mycophenolate mofetil, Cellcept
Emory University, ALS Association
Amyotrophic Lateral Sclerosis (ALS)
01/16
01/16
PEDALI, NCT01757899: Effects and Safety of Infusion of Low-Doses of Methylprednisolone in Early ALI and ARDS in Children

Withdrawn
2
0
RoW
Methylprednisolone Arm, Solumedrol, Sterile Saline Arm, Saline
Universidade Federal do Rio de Janeiro, Instituto de Puericultura e Pediatria Martagão Gesteira - IPPMG/UFRJ, Instituto D'Or de Pesquisa, Rio de Janeiro State Research Supporting Foundation (FAPERJ)
Acute Lung Injury, Acute Respiratory Distress Syndrome
01/16
01/16
NCT00553202: Donor Stem Cell Transplant in Treating Young Patients With Acute Myeloid Leukemia With Monosomy 7, -5/5q-, High FLT3-ITD AR, or Refractory or Relapsed Acute Myelogenous Leukemia

Completed
2
158
Canada, US
anti-thymocyte globulin, Rabbit ATG, RATG-Rabbit, Antithymocyte Globulin, Thymoglobulin, NSC #720095, busulfan, Busulfex, NSC #750, cyclophosphamide, Cytoxan, NSC #26271, cyclosporine, CYA, Sandimmune, Neoral, Gengraf, NSC #290193, methotrexate, MTX, amethopterin, NSC #000740, methylprednisolone, Solu-Medrol, A-Methapred, Medrol, NSC #19987, tacrolimus, FK-506, Prograf, NSC #717865, laboratory biomarker analysis, pharmacological study, allogeneic bone marrow transplantation, bone marrow therapy, allogeneic, allogenic, transplantation, allogeneic bone marrow, allogenic bone marrow, allogeneic hematopoietic stem cell transplantation
Children's Oncology Group, National Cancer Institute (NCI)
Leukemia
06/16
03/20
NCT02425813: Methylprednisolone Sodium Succinate in Treating Patients With Acute Graft-versus-Host Disease of the Gastrointestinal Tract

Withdrawn
2
0
US
Budesonide, Budecort, Butacort, Eltair, Nasocort, Preferid, Pulmicort, Pulmicort Turbuhaler, Rhinocort, Methylprednisolone Sodium Succinate, A-MethaPred, Asmacortone, Cryosolona, Medrate, Metypred, Prednilem, Solu Moderin, Solu-Medrol, Solu-Medrone
Wake Forest University Health Sciences, National Cancer Institute (NCI)
Acute Graft Versus Host Disease, Intestinal Graft Versus Host Disease
07/16
07/16
NCT02711449 / 2015-004800-46: Preoperative Methylprednisolone to Patients Suspected of Appendicitis Undergoing Laparoscopy

Completed
2
78
Europe
Methylprednisolone, Solu-Medrol, 0.9% Saline, Placebo
Jakob Kleif, Zealand University Hospital
Suspected Appendicitis
09/16
09/16
ERAS, NCT02479581: The Safety and Efficacy of the Enhanced Recovery After Surgery()Applied on Cardiac Surgery With Cardiopulmonary Bypass

Completed
2
226
RoW
ERAS group, "yifen®","Flucloxacillin", Recombinant Human Erythropoietin, "Methylprednisolone"，"Solu-Medrol® ", Cardio-pulmonary Bypass measures, during the surgery, Kidney protection measure during the surgery, Lung protection measure during the surgery（Dräger Primus）, Anesthesia drugs during the surgery, Gastrointestinal protection measures after the surgery, Conventional control group, Analgesia drugs after the surgery, scopolamine and morphine, Routine use of anesthesia medicine during the surgery, Routine use of anesthesia medicine after the surgery, Dexamethasone
Xiangya Hospital of Central South University
Valvular Heart Disease
11/16
05/17
NCT02160132: A Controlled Study of Steroids Therapy for Patients of IgA Nephropathy With Active Pathological Changes.

Unknown status
2
180
RoW
Methylprednisolone(intravenously in the 1st-2nd-3rd month ), Methylprednisolone(intravenously in the 1st-3rd-5th month)
Sun Yat-sen University
Glomerulonephritis, IGA, Peripapillary Crescent, Necrosis, Steroid Nephropathy
12/16
12/16
NCT02763761: An Investigational Study of Infliximab With Prednisone or Methylprednisolone Versus Prednisone Combination Treatment in Immune Related or Severe Diarrhea in Patients Treated With Yervoy and/or Opdivo

Withdrawn
2
0
US
Infliximab + Prednisone, Methylprednisolone + Prednisone
Bristol-Myers Squibb
Renal Cell Carcinoma, Melanoma, Lung Cancer
03/17
03/17
NCT02199041: Combined T Cell Depleted Haploidentical Peripheral Blood Stem Cell and Unrelated Umbilical Cord Blood Transplantation in Patients With Hematologic Malignancies Using a Total Lymphoid Irradiation Based Preparative Regimen

Terminated
2
24
US
Cyclophosphamide, Cytoxan, Thiotepa, Thioplex(R), TESPA, TSPA, Fludarabine, Fludara, Melphalan, L-phenylalanine mustard, Phenylalanine mustard, L-PAM, L-sarcolysin, Alkeran, Mesna, Mesnex, G-CSF, Granulocyte colony-stimulating factor (C-CSF), Filgrastim, Neupogen(R), Mycophenolate mofetil, MMF, CellCept(R), Tacrolimus, FK506, Prograf(R), Protopic(R), Methylprednisolone, Medrol(R), Solu-Medrol, Total lymphoid irradiation, TLI, Lymphocyte infusions, Donor lymphocyte infusions, DLI, CliniMACS, Cell Selection System
St. Jude Children's Research Hospital
Hematological Malignancies
05/17
05/17
NCT00565773: Belatacept Post Depletional Repopulation to Facilitate Tolerance

Completed
2
40
US
Belatacept, LEA29Y, Nulojix, Sirolimus, Rapamycin, Alemtuzumab, Campath, Lemtrada
Allan D Kirk, MD, PhD, Bristol-Myers Squibb, Duke University
Organ Transplantation
07/17
07/17
NCT02029638: BMT and High Dose Post-Transplant Cyclophosphamide for Chimerism Induction and Renal Allograft Tolerance

Terminated
2
4
US
anti-thymocyte globulin, ATG, Thymoglobulin, Fludarabine, Cyclophosphamide, cytoxan, Total Body Irradiation, TBI, acetaminophen, Tylenol, diphenhydramine, benadryl, methylprednisolone, bone marrow transplant, bone marrow transfusion, BMT, MESNA, Mesnex, mycophenolate mofetil, MMF, CellCept, prednisone, filgrastim, neupogen
National Institute of Allergy and Infectious Diseases (NIAID), Immune Tolerance Network (ITN)
Kidney Transplantation
09/17
09/17
2017-003564-12: Impact sur la morbidité de l'administration d'une forte dose unique de corticoïdes au moment de l'anesthésie lors d'une chirurgie colorectale

Ongoing
2
109
Europe
Powder for solution for injection, METHYLPREDNISOLONE
CHU Dijon Bourgogne
Chirurgie colorectale élective, Chirurgies du côlon et du rectum, Body processes [G] - Immune system processes [G12]
 
 
NCT02757196: Treatment of ITP With Rituximab and / or Accutane

Unknown status
2
112
NA
Rituximab plus methylprednisolone, monoclone antibody of cluster of differentiation antigen 20, methylprednisolone, intravenous methylprednisolone
Peking University People's Hospital, Beijing Hospital
Immune Thrombocytopenia
12/17
12/18
REACH1, NCT02953678: A Study of Ruxolitinib in Combination With Corticosteroids for the Treatment of Steroid-Refractory Acute Graft-Versus-Host Disease (REACH-1)

Checkmark REACH1 trial in steroid refractory acute GVHD
Dec 2018 - Dec 2018: REACH1 trial in steroid refractory acute GVHD
Checkmark REACH 1 trial in steroid refractory acute GVHD [screenshot]
Jun 2018 - Jun 2018: REACH 1 trial in steroid refractory acute GVHD [screenshot]
Checkmark Data from REACH1 study
More
Completed
2
71
US
Ruxolitinib, Jakafi, INCB018424, Prednisone or methylprednisolone
Incyte Corporation
Graft-versus-host Disease (GVHD)
01/18
08/19
NCT01332617: Phase II Study of Simvastatin for Relapsed/Refractory Myeloma

Withdrawn
2
0
NA
Simvastatin,Zoledronic Acid,Bortezomib,Bendamustine,Methylprednisolone., Simvastatin (ZOCOR), Methylprednisolone (Medrol), Bortezomib (Voltarol, Diclofenac), Bendamustine (Treanda), Zoledronic acid (Zometa, Reclast, Zomera)
University of Louisville, James Graham Brown Cancer Center
Myeloma
02/18
02/19
NCT02260934: Rituximab and Belimumab for Lupus Nephritis

Completed
2
43
US
Rituximab, Rituxan, Cyclophosphamide, Cytoxan, Prednisone, Deltasone, Methylprednisolone, Solu-Medrol, Diphenhydramine, Acetaminophen, Tylenol, Belimumab, Benlysta
National Institute of Allergy and Infectious Diseases (NIAID), Immune Tolerance Network (ITN)
Lupus Nephritis
03/18
02/19
NCT02392780: Cannabidiol for the Treatment of Severe (Grades III/IV) Acute Graft-versus-host Disease

Unknown status
2
10
RoW
Cannabidiol, Methylprednisolone, Calcineurin inhibitor
moshe yeshurun
Acute-graft-versus-host Disease
04/18
 
2018-000620-34: Imatinib treatment for Multiple Sclerosis (MS) Relapses

Ongoing
2
200
Europe
Solu-Medrol, Film-coated tablet, Injection, Solu-Medrol
Department of Clinical Neuroscience, Karolinska Institutet, Vetenskapsrådet
Patients with clinically definite Multiple Sclerosis (MS) according to the McDonald Criteria, or possible MS (also named clinically isolated syndrome-CIS, as a first manifestation of MS, where there are radiological and/or cerebrospinal fluid signs consistent with MS), which display an acute relapse, Patients with Multiple Sclerosis (MS) with a relapse or with symptoms and signs giving rise to high suspicion of MS with relapse, Diseases [C] - Nervous System Diseases [C10]
 
 
NCT02500550 / 2015-002821-20: Safety and Efficacy of Two Doses of ATIR101, a T-lymphocyte Enriched Leukocyte Preparation Depleted of Host Alloreactive T-cells, in Patients With a Hematologic Malignancy Who Received a Hematopoietic Stem Cell Transplantation From a Haploidentical Donor

Checkmark AIR-008 study for GVHD
Jan 2018 - Jan 2018: AIR-008 study for GVHD
Checkmark Safety data readout from CR-AIR-008 trial for GVHD in patients with hematologic malignancies post-HSCT
Dec 2016 - Dec 2016: Safety data readout from CR-AIR-008 trial for GVHD in patients with hematologic malignancies post-HSCT
Completed
2
15
Europe, Canada, RoW
ATIR101, Haploidentical hematopoietic stem cell transplantation (HSCT), TBI regime, Non-TBI regime
Kiadis Pharma
Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome
07/18
12/18
ESHAP, NCT00732498: Rituximab, Yttrium Y 90 Ibritumomab Tiuxetan in Patients W/Relapsed Stage II, III, or IV Follicular NHL

Completed
2
28
US
Methylprednisolone, Methylprednisolone sodium succinate, Solu-Medrol, Etoposide, Vespesid, Cytarabine, Cytosine Arabinoside, Cisplatin, CDDP, Rituximab, Ibritumomab, Rituxan, In-Zevalin, Zevalin, Yttrium-90-Ibritumomab Tiuxetan, Y-Zevalin, Yttrium-90-Ibritumomab Tiuxetan, Zevalin
University of Arizona, National Cancer Institute (NCI)
Lymphoma
10/18
10/18
INCREASE, NCT03387046: A Pilot Study in Participants With Relapsing Remitting Multiple Sclerosis (RR-MS)

Terminated
2
7
Europe
D-aspartate, Placebo, IFN beta-1a, Methylprednisolone
Merck KGaA, Darmstadt, Germany
Multiple Sclerosis, Relapsing-Remitting
01/19
01/19
NOBILITY, NCT02550652 / 2015-002022-39: A Study to Evaluate the Safety and Efficacy of Obinutuzumab Compared With Placebo in Participants With Lupus Nephritis (LN)

Checkmark Efficacy and safety data from NOBILITY trial for lupus nephritis
Nov 2020 - Nov 2020: Efficacy and safety data from NOBILITY trial for lupus nephritis
Checkmark Safety and efficacy data from trial for lupus nephritis at ASN/ACR 2019
Nov 2019 - Nov 2019: Safety and efficacy data from trial for lupus nephritis at ASN/ACR 2019
Checkmark Safety and efficacy data from NOBILITY trial in lupus nephritis
More
Completed
2
126
Europe, US, RoW
Mycophenolate Mofetil/Mycophenolic Acid, Obinutuzumab, Gazyva, GA101, RO5072759, Placebo, Methylprednisolone, Prednisone
Hoffmann-La Roche
Lupus Nephritis
01/19
08/23
EFFRITE, NCT02545959: Intrathecal Rituximab in Progressive Multiple Sclerosis

Completed
2
10
Europe
Rituximab IT, intrathecal rituximab (Mabthera), methylprednisolone IV, Solumedrol, Rituximab IV, Mabthera
Centre Hospitalier de PAU, University Hospital, Bordeaux
Multiple Sclerosis, Chronic Progressive, Nervous System Diseases
02/19
09/19
2018-002790-22: Efficacy evaluation of tocilizumab in the treatment Graves' Orbitopathy Valutazione dell’efficacia di tocilizumab nel trattamento dell’orbitopatia basedowiana

Not yet recruiting
2
64
Europe
Roactemra, SOLU MEDROL, Tocilizumab, SOLU MEDROL, Concentrate for solution for infusion, Powder and solvent for solution for injection, ROACTEMRA - 20 MG/ML CONCENTRATO PER SOLUZIONE PER INFUSIONE - USO ENDOVENOSO - FLACONCINO (VETRO) 4ML 1 FLACONCINO, SOLU MEDROL - 500 MG/8 ML POLVERE E SOLVENTE PER SOLUZIONE INIETTABILE 1 FLACONE DI POLVERE DA 500 MG+ FIALA SOLVENTE DA 8 ML
FONDAZIONE IRCCS CA' GRANDA OSPEDALE MAGGIORE POLICLINICO, Roche S.p.A.
Active moderate-severe Graves' Orbitopathy Orbitopatia basedowiana di grado moderato-severo in fase attiva, Garcves' Orbitopathy in the zacute inflammatory phase Oftalmopatia di Basedow in fase infiiammatoria acuta, Diseases [C] - Hormonal diseases [C19]
 
 
NCT04467892: Low Versus High Corticosteroid Use in Ventilator Associated Pneumonia

Completed
2
240
RoW
methylprednisolone, Methyl Prednisolonate, ventilators
King Abdul Aziz Specialist Hospital
Ventilator Associated Pneumonia
02/20
02/20
NCT04355247: Prophylactic Corticosteroid to Prevent COVID-19 Cytokine Storm

Unknown status
2
20
US
MethylPREDNISolone 80 Mg/mL Injectable Suspension
Auxilio Mutuo Cancer Center
Covid-19
07/20
04/21
NCT02294357: Weekly 70 mg/m2 Carfilzomib for Multiple Myeloma Patients Refractory to 27 mg/m2 Carfilzomib

Terminated
2
45
US
Carfilzomib, Kyprolis, Dexamethasone, Decadron, Dexamethasone acetate, Prednisone, Deltasone, Cortan, Methylprednisolone, Medrol, Methylprednisolone acetate, Lenalidomide, Revlimid, Pomalidomide, Pomalyst
Oncotherapeutics, Amgen
Multiple Myeloma
09/20
09/20
NCT01319981: Hyper-CVAD With Liposomal Vincristine in Acute Lymphoblastic Leukemia

Completed
2
31
US
Rituximab, Rituxan, Imatinib, Imatinib Mesylate, Gleevec, ST1571, NSC-716051, Cyclophosphamide, Cytoxan, Neosar, Doxorubicin, Adriamycin, Rubex, Mesna, Mesnex, VSLI, Liposomal Vincristine, Vincristine Sulfate Liposomes Injection, Marqibo, Solu-Medrol, Methylprednisolone, Depo-Medrol, Medrol, Methotrexate, Ara-C, Cytarabine, Cytosar, DepoCyt, Cytosine Arabinosine Hydrochloride, G-CSF, Filgrastim, Neupogen, Pegfilgrastim, Neulasta, Dexamethasone, Decadron
M.D. Anderson Cancer Center, Spectrum Pharmaceuticals, Inc
Leukemia
11/20
11/20
NCT02133924: Multicenter Study Of Natalizumab Plus Standard Steroid Treatment For High Risk Acute Graft-Versus-Host Disease

Checkmark Data from trial for acute GVHD
Sep 2020 - Sep 2020: Data from trial for acute GVHD
Completed
2
76
US
natalizumab, Tysabri, steroids, Prednisone, methylprednisolone equivalent IV
John Levine, Biogen
Acute Graft Versus Host Disease
12/20
11/21
STAGO, NCT03110848 / 2018-001317-33: Effects of Atorvastatin in Graves' Orbitopathy (GO)

Completed
2
88
Europe
Atorvastatin, Statins, Methylprednisolone, Intravenous glucocorticoids
University of Pisa
Thyroid Associated Ophthalmopathy, Hypercholesterolemia
04/21
04/21
NCT02495077: Effects of Inhibiting Early Inflammation in Kidney Transplant Patients

Completed
2
290
Canada, US
Infliximab, Remicade®, Methylprednisolone, Solu-Medrol, Mycophenolate Mofetil, MMF, CellCept®, Tacrolimus, FK-506, FR-900506, Prograf®, Thymoglobulin®, Antithymocyte Globulin [Rabbit], Rabbit ATG, Acetaminophen, Tylenol®, Loratadine, Claritin®, Placebo for Infliximab, Prednisone, Diphenhydramine, Benadryl
National Institute of Allergy and Infectious Diseases (NIAID), Clinical Trials in Organ Transplantation, Rho Federal Systems Division, Inc.
Kidney Transplant
07/21
07/21
NCT03701698: Ruxolitinib and Steroid as First Line Therapy for Acute GVHD

Unknown status
2
30
RoW
Ruxolitinib Oral Tablet, Jakafi, Methylprednisolone, steroid
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Acute GVHD
10/21
10/21
2021-000641-41: Sirolimus vs Corticosteroids in Treatment of Thyroid Eye Disease

Not yet recruiting
2
70
Europe
Powder and solvent for solution for injection, Tablet, Solu-Medrol, Rapamune
Helse Bergen HF, Haukeland University Hospital, HelseVest
Thyroid Eye Disease (TED) in patients with Graves' Diease., Thyroid Eye Disease (TED) in patients with Graves' Diease., Diseases [C] - Eye Diseases [C11]
 
 
STEROHCA, NCT04624776: Steroid Treatment After Resuscitated Out-of-Hospital Cardiac Arrest

Completed
2
158
Europe
Methylprednisolone, Solu-Medrol, Isotonic saline, Placebo
Christian Hassager
Out-Of-Hospital Cardiac Arrest, Cardiac Arrest, Cardiac Arrest With Successful Resuscitation, Post Cardiac Arrest Syndrome, Systemic Inflammatory Response Syndrome, Neurological Injury
07/22
02/23
NCT05134181: Ultrasound Guided Intra-sacroiliac Joint Injection: Methylprednisolone Versus Triamcinolone

Recruiting
2
45
RoW
sacroiliac joint injection
Mansoura University
Sacroiliac Joint Arthritis
08/22
12/22
NCT03388008: Belatacept Pilot Study in Lung Transplantation Immunosuppression in Lung Transplantation

Completed
2
27
US
Belatacept, Nulojix, Tacrolimus, Prograf, ATG, Thymoglobulin, Mycophenolate Mofetil, Cellcept, Myfortic, Methylprednisolone, Solumedrol, Prednisone
Washington University School of Medicine, National Heart, Lung, and Blood Institute (NHLBI), Bristol-Myers Squibb
Lung Transplant Rejection, Antibody-mediated Rejection
08/22
08/22
NCT04903054: Selective CD28 Blockade in Renal Transplant Recipients

Withdrawn
2
54
US
Lulizumab, BMS-931699, anti-CD28 domain antibody (anti-CD28 dAb), Tacrolimus, Prograf®, Thymoglobulin®, antithymocyte globulin, Methylprednisolone, corticosteroid, Mycophenolate Mofetil, MMF, CellCept®, Prednisone
National Institute of Allergy and Infectious Diseases (NIAID), Bristol-Myers Squibb, PPD
Kidney Transplantation, Renal Transplant Recipients
09/22
09/22
NCT03913702: Subacromial Methylprednisolone Versus Ketorolac for Shoulder Impingement

Terminated
2
1
US
Ketorolac Tromethamine, Toradol, Methylprednisolone Acetate, DepoMedrol
The University of Texas Medical Branch, Galveston
Subacromial Impingement, Subacromial Impingement Syndrome
11/22
11/22
NCT02582775: MT2015-20: Biochemical Correction of Severe EB by Allo HSCT and Serial Donor MSCs

Completed
2
17
US
Thymoglobulin, ATG, anti-thymocyte globulin, Cyclophosphamide, Cytoxan, Fludarabine, fludarabine phosphate, Fludara, Total Body Irradiation, TBI, Bone marrow infusion, HCT, Tacrolimus, Prograf, Mycophenolate Mofetil, MMF, Donor mesenchymal stem cell infusions, Busulfan
Masonic Cancer Center, University of Minnesota
Epidermolysis Bullosa
11/22
07/23
TOGO, NCT04876534: Tocilizumab in Active Moderate-severe Graves' Orbitopathy

Recruiting
2
64
Europe
Tocilizumab 20 Mg/mL Intravenous Solution, Actemra, MethylPREDNISolone Injectable Solution, Solumedrol
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Mauriziano Umberto I Hospital, Istituto Auxologico Italiano, Azienda Ospedaliera "Sant'Andrea", Azienda Ospedaliero, Universitaria Pisana
Graves Ophthalmopathy
12/22
12/23
NCT03674099: Imatinib for Multiple Sclerosis (MS) Relapses

Recruiting
2
200
Europe
Imatinib Mesylate, Methylprednisolone
Tomas Olsson, The Swedish Research Council
Multiple Sclerosis
12/22
07/23
NCT04251832: Efficacy of Sodium Thiosulfate in Shoulder Pain in Calcific Tendinitis of the Rotator Cuff

Recruiting
2
80
Europe
Sodium Thiosulfate
Soraia Azevedo
Sodium Thiosulfate, Calcific Tendinitis, Shoulder Pain
12/22
12/22
NCT04061876: First Line Therapy for High Risk Acute GVHD

Completed
2
198
RoW
Ruxolitinib, New, Corticosteroid, Traditional
Chinese PLA General Hospital, LU DAOPEI MEDICAL, 960th Hospital of PLA, The Second Hospital of Hebei Medical University, The Second Affiliated Hospital of Dalian Medical University, Air Force Military Medical University, China
aGVHD, Stem Cell Transplant Complications
08/22
06/23
IN-DXM-EMRR, NCT06223074: Improving the Treatment of Acute Relapses in Multiple Sclerosis Through Intranasal Methylprednisolone Administration

Enrolling by invitation
2
80
RoW
IV Methylprednisolone administration, ST, Nasal Methylprednisolone (MT), Nasal MT
Universidad Nacional Autonoma de Mexico, Instituto Nacional de Neurología y Neurocirugía
Methylprednisolone, Intranasal Administration, Patients With an Active Multiple Sclerosis Relapse
11/24
02/25
2020-000855-11: USING STEROID TREATMENT TO INHIBIT INFLAMMATION AND BRAIN INJURY IN PATIENTS RESUSCITATED FROM CARDIAC ARREST. BRUG AF STEROIDBEHANDLING TIL AT MINDSKE INFLAMMATION OG HJERNESKADE I GENOPLIVEDE HJERTESTOPSPATIENTER.

Not yet recruiting
2
120
Europe
Solu-medrol, 6132, Solution for injection, Solu-Medrol
Department of Cardiology, Copenhagen University Hospital Rigshospitalet, Copenhagen University Hospital Rigshospitalet
We investigate the efficacy of commercially available glucocorticoid "methylprednisolone" (Solu-Medrol) for reducing the systemic inflammatory response and neurological injury in patients resuscitated after out-of-hospital cardiac arrest. Vi undersøger den antiinflammatoriske og neuroprotektive effekt af det kommercielt tilgængelige glukokortikoid "methylprednisolon" (Solu-Medrol) i patienter genoplivet efter hjertestop uden for hospital., Patients resuscitated from out-of-hospital cardiac arrest have a high mortality due to a systemic inflammatory response and severe brain injury. We hope that Solu-Medrol can prevent this response. Patienter genoplivet efter hjertestop uden for hospital har en høj dødelighed grundet et inflammatorisk respons og svær hjerneskade. Vi håber at Solu-Medrol kan modvirke dette respons., Diseases [C] - Cardiovascular Diseases [C14]
 
 
NCT02661035: Allo HSCT Using RIC for Hematological Diseases

Completed
2
156
US
Allopurinol, Zyloprim, Fludarabine, Fludara, Cyclophosphamide, Cytoxan, ATG, Anti-thymocyte globulin, TBI, Total body irradiation, Tacrolimus, Prograf, MMF, Mycophenolate Mofetil, Peripheral Blood Stem Cells, Related or Unrelated Bone Marrow Cells
Masonic Cancer Center, University of Minnesota
Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia, Chronic Myelogenous Leukemia, Plasma Cell Leukemia, Myelodysplastic Syndromes, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, B-Cell Lymphoma, Follicular Lymphoma, Lymphoplasmacytic Lymphoma, Mantle-Cell Lymphoma, Prolymphocytic Leukemia, Lymphoblastic Lymphoma, Burkitt's Lymphoma, Non-Hodgkin's Lymphoma, Multiple Myeloma, Myeloproliferative Syndromes, Hematological Diseases
04/23
05/23
NCT04305145: Infliximab for Treatment of Immune Checkpoint Inhibitor Colitis

Recruiting
2
42
US
Infliximab, AVSOLA, Ixifi, Remicade, Renflexis, Methylprednisolone, Solu-Medrol, Duralone, Medralone, Medrol, M-Prednisol, Prednisone, Deltasone, Prednicot, predniSONE Intensol, Rayos, Sterapred, Sterapred DS
Massachusetts General Hospital, Dana-Farber Cancer Institute
Melanoma Stage III, Melanoma Stage IV, Skin Cancer Stage III, Skin Cancer Stage IV, Drug-Induced Colitis, Drug Toxicity, Immune-related Adverse Event
06/30
06/30
 

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