| furosemide / Generic mfg. |
| Completed | N/A | 200 | Canada | intravenous saline hydration + mannitol + furosemide, intravenous saline hydration | University of Alberta, Alberta Heritage Foundation for Medical Research | Contrast-induced Nephropathy, Acute Renal Failure, Chronic Renal Failure | 10/00 | | | |
NCT00778180: Bioequivalence Study of Furosemide 80mg Tablets Under Fasting Conditions |
|
|
| Completed | N/A | 44 | US | furosemide 80 mg tablets | Ranbaxy Laboratories Limited | Healthy | 10/05 | 11/05 | | |
NCT00249067: Retrospective Evaluation of Carvedilol Versus Captopril in CHF Patients |
|
|
| Terminated | N/A | 50 | US | | Children's Healthcare of Atlanta | Heart Failure, Heart Murmurs | | 10/05 | | |
NCT00240019: Maximizing the Benefit of Renin-Angiotensin Blocking Drugs in Diabetic Renal Disease. |
|
|
| Completed | N/A | 30 | US | Addition of furosemide 20 mg oral bid to baseline regimen | Stanford University, National Institutes of Health (NIH) | Diabetic Nephropathy | | 04/06 | | |
| Terminated | N/A | 32 | Europe | Cardura XL 4 mg bd, Amiloride 5 mg bd, Furosemide 40 mg bd | St George's, University of London | Hypertension | | 10/06 | | |
NCT00285805: The Influence of Rosiglitazone on the Diuretic Effect of Furosemide and Amiloride |
|
|
| Completed | N/A | 13 | Europe | Rosiglitazone versus placebo, response (sodium excretion) to amiloride infusion, response (sodium excretion) to furosemide infusion | Radboud University Medical Center | Insulin Resistance | 10/06 | 11/06 | | |
NCT00568009 / 2007-000490-40: Study to Evaluate the Effect of SLV320 in Addition to Chronic Furosemide Treatment on Renal Function in Subjects With Congestive Heart Failure and Impaired Renal Function |
|
|
| Terminated | N/A | 300 | US, Europe, RoW | SLV320 | Solvay Pharmaceuticals, Quintiles, Inc. | Congestive Heart Failure | 11/08 | 11/08 | | |
| Completed | N/A | | US | Chlorthalidone, Furosemide | US Department of Veterans Affairs | Hypertension | | | | |
| Completed | N/A | 12 | Europe | furosemide | Assistance Publique - Hôpitaux de Paris, Institut National de la Santé Et de la Recherche Médicale, France | Acromegaly | 12/09 | 12/09 | | |
NCT00924014: Comparing the Effects of Conivaptan and Diuretics on Plasma Neurohormones and Renal Blood Flow in Patients With Chronic Congestive Heart Failure |
|
|
| Unknown status | N/A | 8 | US | Conivaptan, vaprisol, Furosemide, Lasix, Conivaptan and furosemide, lasix | Hennepin County Medical Center, Minneapolis, Astellas Pharma Inc | Heart Failure | 12/09 | 03/10 | | |
NCT00962286: Effect of Furosemide on Obesity-induced Glomerular Hyperfiltration |
|
|
| Terminated | N/A | 3 | RoW | Furosemide | Rabin Medical Center | Obesity-induced Hyperfiltration | 05/10 | 07/10 | | |
NCT00945386: The Effect of Continuous, Various Doses of Furosemide Drip on Hearing as Measured by Acoustic Emission |
|
|
| Unknown status | N/A | 60 | RoW | | Rabin Medical Center | Hearing Status | | 08/10 | | |
NCT01072071: The Influence of Furosemide on Fluid Balance and Intra-abdominal Pressure in Critically Ill Patients |
|
|
| Unknown status | N/A | 30 | Europe | furosemide, Lasix (Sanofi-Aventis) | Ziekenhuis Netwerk Antwerpen (ZNA) | Intra-Abdominal Hypertension | 12/11 | 03/12 | | |
| Terminated | N/A | 23 | US | Furosemide, Lasix, Placebo, Saline | Northwestern University | Brain Swelling, Brain Edema, Dehydration | 03/12 | 03/12 | | |
NCT01318967: Measurement of Kidney Blood Flow and Oxygen Levels by MRI |
|
|
| Completed | N/A | 10 | US | Furosemide, Lasix, Placebo | Wake Forest University | Chronic Kidney Disease | 06/12 | 06/13 | | |
NCT01457053: Assessment of Coronary Flow Reserve in Heart Failure Patients After Ultrafiltration Versus Diuretics |
|
|
| Terminated | N/A | 4 | US | Loop diuretics (furosemide, torsemide, bumetanide), Lasix, furosemide, Bumex, bumetanide, Demadex, torsemide, Ultrafiltration, Aquadex System 100 ultrafiltration device | University of Cincinnati | Acute Decompensated Heart Failure | 05/13 | 05/13 | | |
SHUM, NCT01617798: Stop Hypernatremia, Use Metolazone, for Aggressive, Controlled, Effective Diuresis |
|
|
| Withdrawn | N/A | 0 | US | Supplemental metolazone diuresis, furosemide, lasix, Placebo Comparator: Control-- furosemide (lasix) only, furosemide, lasix, metolazone | Oregon Health and Science University | Respiratory Failure, Volume Overload, Hypernatremia | 06/13 | 06/13 | | |
NCT01584518: B-type Natriuretic Peptide as a Surrogate Marker Guiding Post-operative Fluid Off-loading |
|
|
| Completed | N/A | 50 | US | Furosemide, Brand name: Lasix | Creighton University | Fluid Over-load | 06/13 | 06/13 | | |
NCT01705470: Furosemide Treatment Before Blood Transfusion in Patients With Systolic Dysfunction |
|
|
| Withdrawn | N/A | 0 | RoW | furosemide, placebo normal saline | Tel-Aviv Sourasky Medical Center | Anemia Treatment Among Patients Suffering From Left Ventricular Systolic Dysfunction | 06/13 | 06/13 | | |
| Completed | N/A | 77 | US | Furosemide, Lasix | George Washington University | Acute Kidney Failure | 12/13 | 12/13 | | |
NCT01146288: Effect of Acetazolamide and Furosemide on Obesity-induced Glomerular Hyperfiltration |
|
|
| Completed | N/A | 13 | RoW | Furosemide first, then Acetazolamide, Acetazolamide first, then Furosemide | Rabin Medical Center | Obesity-induced Hyperfiltration | 05/14 | 05/14 | | |
AVOID-HF, NCT01474200: Study of Heart Failure Hospitalizations After Aquapheresis Therapy Compared to Intravenous (IV) Diuretic Treatment |
|
|
| Terminated | N/A | 224 | US | Isolated veno-venous ultrafiltration (AQ), Aquapheresis, Ultrafiltration, Aquadex FlexFlow System, Gambro UF Solutions, IV Loop Diuretics (LD), furosemide | Nuwellis, Inc. | Heart Failure, Cardiac Failure, Acute Decompensated Heart Failure (ADHF) | 07/14 | 07/14 | | |
| Completed | N/A | 47 | RoW | mannitol, Furosemide, Lasix, placebo | Istanbul University | Brain Tumors | 05/15 | 11/15 | | |
NCT01709227: Peritoneal Dialysis vs Furosemide for Acute Kidney Injury After Cardiopulmonary Bypass |
|
|
| Completed | N/A | 73 | US | Furosemide, Lasix, Peritoneal Dialysis, PD | Children's Hospital Medical Center, Cincinnati | Acute Kidney Injury | 06/15 | 06/15 | | |
NCT01817803: A Prospective, Single-center, Open-label, Pilot Study to Compare the Effectiveness and Safety of Diuretics Add-On Strategy in Chronic Heart Failure Patients (DIOS 1) |
|
|
| Withdrawn | N/A | 0 | RoW | furosemide/no spironolactone, metolazone/no spironolactone, furosemid/spironolactone, metolazone/spironolactone | Yonsei University | Congestive Heart Failure | 06/15 | 12/15 | | |
NCT02373735: Effect of SVV Guided Fluid Therapy on Blood Loss and Postoperative Outcomes |
|
|
| Completed | N/A | 64 | RoW | crystalloid, Hartmann's solution, colloid, volulyte, mannitol, lasix | Asan Medical Center | Bladder Cancer | 11/15 | 12/15 | | |
NCT02047422: A Prospective, Single-center, Randomized, Controlled, Open-label, Pilot Study to Compare the Effectiveness and Safety of DIuretics Add-On Strategy in Acute Decompensated Heart Failure Patients (DIOS II) |
|
|
| Withdrawn | N/A | 0 | RoW | Furosemide, metolazone, furosemid/spironolactone, metolazone/spironolactone | Yonsei University | Congestive Heart Failure | 02/16 | 02/16 | | |
| Completed | N/A | 30 | Europe | Not intervention | Henri Mondor University Hospital | Treatment by Furosemide | 02/16 | 02/16 | | |
NCT03547895: Management of Decompensated HCV Cirrhotic Patients |
|
|
| Completed | N/A | 80 | NA | Sofosbuvir 400mg (Sovaldi) + Daclatasvir 60 mg (Daklinza) + Ribavirin 200 mg (Rebetol), Direct Acting Antivirals (DAAs), vitamin K (Phytomenadione) 10 mg+ furosemide and spironolactone (Lasilactone) 50 mg + milk thistle (Silymarin) 140 mg + Albumin infusion, liver support therapy | Zagazig University | Decompensated Cirrhosis | 05/16 | 06/18 | | |
NCT01690039: Influence of Polymorphisms in the ATP6V1 Gene of the V-ATPase on the Development of Incomplete Distal Renal Tubular Acidosis |
|
|
| Completed | N/A | 170 | Europe | Furosemide-Fludrocortisone-Test (test for urinary acidification), Application of Furosemide (Lasix® ) and Fludrocortisone (Florinef®) | University Hospital Inselspital, Berne | Acidosis, Renal Tubular, Nephrolithiasis, Vacuolar Proton-Translocating ATPases | 12/16 | 05/17 | | |
NCT02730117: Furosemide Stress Test Guiding Initiation of Renal Replacement Therapy |
|
|
| Completed | N/A | 118 | RoW | Dialysis with continuous renal replacement therapy, Mechanical ventilator, Anti-Bacterial Agents, cephalosporin, carbapenem, Vasopressors, Norepinephrine, Dopamine, Milrinone, Dobutamine | Chulalongkorn University | Acute Kidney Injury | 07/17 | 07/17 | | |
ChiCTR-IOR-14005250: Left Ventricular End-Diastolic Pressure and Brain Natriuretic Peptide Guided Low-Dose Furosemide for Preventing Contrast-induced Nephropathy in the Percutaneous Coronary Intervention |
|
|
| Recruiting | N/A | 1140 | | hydration + furosemide ;hydration + apply furosemide Individually | The Second Hospital of Hebei Medical University; Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Troditional and Chinese Medicine, The project of Hebei Provincial Health Department | Contrast-induced Nephropathy | | | | |
NCT02068937: Effectiveness of a Diuretic Algorithm in Clinical Stability in Heart Failure Patients |
|
|
| Completed | N/A | 206 | RoW | Furosemide and Phone contact, phone calls, Furosemide, Control Group | Hospital de Clinicas de Porto Alegre | Heart Failure | 12/17 | 12/17 | | |
ChiCTR1800017270: Exploration of recombinant hypertonic saline combined with furosemide in the treatment of heart failure |
|
|
| Recruiting | N/A | 522 | | C-HSS (100ml) combined with furosemide (40mg) ;furosemide (40mg) | Cangzhou Central Hospital; Cangzhou Central Hospital, no | heart failure | | | | |
NCT01508260: Ultrafiltration (Aquapheresis) in Patients With Leukemia and Severe Fluid Overload |
|
|
| Withdrawn | N/A | 0 | US | Aquapheresis, Aquadex pump, Furosemide, Furomide, Lasix | M.D. Anderson Cancer Center | Leukemia | 03/18 | | | |
NCT02800135: Performance of Diuretic Stress Test in Predicting Short Term Renal Recovery in Oliguric Critically-ill Patients Recovery in the Short Term |
|
|
| Terminated | N/A | 93 | Europe | Furosemide | Centre Hospitalier Universitaire de Saint Etienne | Critical Illness, Oliguria | 03/18 | 03/18 | | |
NCT03082742: The Effect of Diuretics on Mineral and Bone Disorder in Chronic Kidney Disease Patients |
|
|
| Unknown status | N/A | 52 | RoW | Hydrochlorothiazide, Furosemide | University of Sao Paulo General Hospital | Secondary Hyperparathyroidism, Chronic Kidney Disease | 06/18 | 06/18 | | |
ChiCTR-EOC-16009980: A cohort study on salt sensitivity of blood pressure related genes and environmental risk factors survey and construction of risk prediction model |
|
|
| Recruiting | N/A | 1950 | | Modified Sullivan acute oral saline load and furosemide sodium excretion volume reduction test ;Modified Sullivan acute oral saline load and furosemide sodium excretion volume reduction test | Capital Medical University; Capital Medical University, National Natural Science Foundation of China | Hypertension | | | | |
| Recruiting | N/A | 60 | | Rrestricted fluid ;Open fluid input and furosemide are given ;Goal-directed fluid therapy | Department of Anesthesiology, Shengjing Hospital, China Medical University; Shengjing Hospital, China Medical University, No | Colorectal Cancer | | | | |
ChiCTR1800017639: A randomized controlled trial for perioperative administration of tolvaptan in improving postoperative recovery in patients with cirrhosis |
|
|
| Recruiting | N/A | 240 | | Tolvaptan + Furosemide ;Furosemide | Shanghai Public Health Clinical Center; Shanghai Public Health Clinical Center, self-financing | liver cirrhosis | | | | |
| Completed | N/A | 1411 | Europe | diuretics, hydrochlorothiazide, bumetanide, furosemide, albumin, fluid restriction, renal replacement, ultrafiltration | Central Hospital, Nancy, France, Ministry of Health, France | Fluid Shifts, Critical Care | 07/19 | 05/20 | | |
NCT04215419: The Furosemide Stress Test, Electrolytes Response and Renal Index in Critically Ill Patients |
|
|
| Completed | N/A | 40 | Europe | | Hospital San Paolo | Acute Kidney Injury | 10/19 | 12/19 | | |
ChiCTR1800014902: Dehydration treatment and renal protection of older patients with acute decompensated heart failure (simple loop diuretics vs combined multi-target diuretics): a prospective randomized controlled study |
|
|
| Not yet recruiting | N/A | 200 | | furosemide+ AVP-V2A+rhBNP ;simple loop diuretics | Chinese PLA General Hospital; Chinese PLA General Hospital, Open fund from national center of clinical medical research on geriatric diseases | acute decompensated heart failure | | | | |
NCT04982874: Bioequivalence Study of Furosemide 40 mg Tablet in 24 Indonesian Healthy Volunteers |
|
|
| Completed | N/A | 24 | RoW | Furosemide 40 mg, Lasix® 40 mg Tablet | PT. Kimia Farma (Persero) Tbk, PT Pharma Metric Labs | Drug Use | 01/20 | 01/20 | | |
NCT04182854: Use of Diuretics in Maintenance Hemodialysis Patients Undergoing Bioimpedance-guided Fluid Management |
|
|
| Recruiting | N/A | 46 | RoW | Furosemid hydrochlorothiazide | Capital Medical University | Diuretic Abuse | 02/20 | 07/21 | | |
ChiCTR1800015215: Comparison of Usefulness of furosemide and budesonide Nebulizations for Attenuating Postoperative Sore Throat |
|
|
| Recruiting | N/A | 81 | | aerosol inhalation of furosemide 40mg ;aerosol inhalation of budesonide 2mg ;0.9% N.S | Plastic Surgery Hospital, The Chinese Academy of Medical Sciences, Peking Union Medical College; Plastic Surgery Hospital, The Chinese Academy of Medical Sciences, Peking Union Medical College, Self -funding | Postoperative Sore Throat | | | | |
NCT04156451: Effect of Fluid Deresuscitation With Central Venous Pressure Target 0-4 mmHg in Septic Shock Patients |
|
|
| Recruiting | N/A | 44 | RoW | Fluid resuscitation and furosemide administration (bolus and continuous) with central venous pressure target 8 - 10 mmHg, Fluid deresuscitation and furosemide administration (bolus and continuous) with central venous pressure target 0 - 4 mmHg | Indonesia University | Septic Shock | 09/20 | 11/20 | | |
NCT04467931: ACEI or ARB and COVID-19 Severity and Mortality in US Veterans |
|
|
| Completed | N/A | 22213 | US | ACEI/ARB, benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, quinapril, ramipril, trandolapril, azilsartan, candesartan, eprosartan, irbesartan, losartan, olmesartan, telmisartan, valsartan, Non-ACEI/ARB, doxazosin, prazosin, terazosin, acebutolol, nebivolol, atenolol, betaxolol, bisoprolol, metoprolol, pindolol, penbutolol, carvedilol, labetalol, nadolol, propranolol, timolol, amlodipine, felodipine, isradipine, nifedipine, nicardipine, nisoldipine, diltiazem, verapamil, clonidine, guanfacine, guanabenz, methyldopa, reserpine, hydralazine, minoxidil, aliskiren, spironolactone, eplerenone, bumetanide, furosemide, ethacrynic acid, torsemide, amiloride, triamterene, bendroflumethiazide, chlorothiazide, chlorthalidone, hydrochlorothiazide, indapamide, metolazone, ACEI, ARB | University of Utah, VA Salt Lake City Health Care System, University of Pennsylvania, Wake Forest University Health Sciences, University of Florida, Johns Hopkins Bloomberg School of Public Health, Boston University, Northwestern University, Edith Nourse Rogers Memorial Veterans Hospital, Columbia University, MedStar Georgetown University Hospital | Hypertension, COVID | 10/20 | 12/20 | | |
ChiCTR1900021724: Prevention of contrast-induced acute kidney injury by furosemide with standard hydration in high risk patients undergoing coronary interventional procedures: A randomized controlled trial |
|
|
| Not yet recruiting | N/A | 230 | | Continuous intravenous infusion of furosemide was performed at 0.2-0.5mg/kg for 24 hours after coronary interventional procedures ;Continuous intravenous infusion of Normal saline was performed at 1-1.5ml/kg /h for 12 hours before operation and 24 hours after operation | Zhongda Hospital of Southeast University; Zhongda Hospital of Southeast University, Self-financing | Contast-induced Acute Kidney Injury | | | | |
ChiCTR1900023793: A study for prevention and treatment of complications associated with fluid extravasation during shoulder arthroscopy by perioperative intervention |
|
|
| Not yet recruiting | N/A | 180 | | furosemide ;methylprednisolone ;ulinastatin ;saline ;furosemide+ methylprednisolone ;furosemide+ulinastatin | Sichuan Provincial Orthopedic Hospital; Sichuan Provincial Orthopedic Hospital, Health and Family Planning Commission of Sichuan Province | Complications associated with fluid extravasation during shoulder arthroscopy | | | | |
ChiCTR1900022989: A prospective, randomized, controlled trial for mirilone for controlled low central venous pressure in hepatectomy |
|
|
| Recruiting | N/A | 90 | | R-L ml/kg/h + lasix 10mg/time ;glycerin 0.1-0.6ug/kg/min ;mirilone0.5ug/kg/min | the First Affiliated Hospital of Sun Yatsen University; the First Affiliated Hospital of Sun Yatsen University, self-funded | hepatectomy | | | | |
NCT04397991: Inhaled Furosemide for Transient Tachypnea of Newborn |
|
|
| Completed | N/A | 64 | RoW | Furosemide, Placebo | Makassed General Hospital | Respiratory Morbidity | 08/21 | 08/21 | | |
NCT02649998: Short-term Efficacy of Furosemide, Isosorbide Dinitrate and Their Combination in ADHF |
|
|
| Withdrawn | N/A | 174 | RoW | Furosemide, Lasix, Isosorbide Dinitrate, Isoket | Chinese University of Hong Kong | Heart Decompensation | 12/21 | 06/22 | | |
ChiCTR2000041236: Prevention and treatment of complications associated with fluid extravasation during shoulder arthroscopy: a randomized controlled double-blind trial |
|
|
| Recruiting | N/A | 90 | | furosemide ;methylprednisolone ;saline | Sichuan Provincial Orthopedic Hospital; Sichuan Provincial Orthopedic Hospital, Sichuan and Technology Department of Sichuan Province | Complications associated with fluid extravasation during shoulder arthroscopy | | | | |
ChiCTR2000031981: Predictive value of furosemide stress test combined with biomarker detection in children with acute renal injury |
|
|
| Recruiting | N/A | | | | The First Affiliated Hospital of Sun Yat-Sen University; The First Affiliated Hospital of Sun Yat-Sen University, self-raised | acute kidney injury | | | | |
NCT05304702: Lung Injury (Pulmonary Edema) in COVID-19: Treatment With Furosemide and Negative Fluid Balance (NEGBAL) |
|
|
| Completed | N/A | 120 | RoW | | Clinica Colon | COVID-19 | 03/22 | 03/22 | | |
NCT01275729: The Effect of Loop Diuretics on Severity and Outcome of Acute Kidney Injury |
|
|
| Completed | N/A | 96 | US | Furosemide, Laisx | University of Chicago | Acute Kidney Failure | 06/22 | 06/22 | | |
Lunar OI, NCT06467825: Effect of Sex on Orthostatic Intolerance and Cardiovascular Response During Lunar Descent and Ascent |
|
|
| Recruiting | N/A | 38 | US | Potassium Supplement, Furosemide 20 MG, Lasix, Compression Garment | National Aeronautics and Space Administration (NASA) | Healthy | 09/25 | 09/25 | | |
NCT05520658: Evaluation of the Efficacy of Intralesional Injection of Combined Digoxin and Furosemide Versus 5 - Fluorouracil in Treatment of Plantar Warts |
|
|
| Recruiting | N/A | 60 | RoW | combined digoxin and furosemide, 5 fluorouracil | Sohag University | Plantar Wart | 09/22 | 09/22 | | |
NCT04972617: Characterization of the Efficacy of Furosemide Depending on Albumin Function |
|
|
| Completed | N/A | 50 | Europe | albumin function analysis (ABIC), analysis of total furosemide concentration | University of Rostock | Acute Renal Failure, Critical Illness | 10/22 | 10/22 | | |
NCT05569655: Efficacy and Safety Evaluation of Tolvaptan in the Treatment of Patients With RHF Caused by PAH |
|
|
| Recruiting | N/A | 100 | RoW | Tolvaptan, Samsca, Furosemide, LASâ…¨ | Chinese Pulmonary Vascular Disease Research Group | Pulmonary Arterial Hypertension, Randomized Controlled Trial | 11/22 | 12/22 | | |
NCT05379257: A Feasibility Non-inferiority Clinical Trial for Dosing of Diuretics in CHF Patients |
|
|
| Recruiting | N/A | 12 | RoW | Random dosage and time of furosemide | Hadassah Medical Organization | Congestive Heart Failure | 12/22 | 12/22 | | |
ChiCTR2000033400: Canceled by the investigator Comparison of Usefulness of furosemide and physiological saline Nebulizations for Attenuating Postoperative Sore Throat |
|
|
| Suspended | N/A | 100 | | inhale furosemide ;inhale physiological saline | Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College; Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Self -funding | Postoperative Sore Throat | | | | |
FLUSH-NS, NCT03750136: Furosemide Alone or Unexpectedly With Solution of Hypertonic Saline in Nephrotic Syndrome |
|
|
| Recruiting | N/A | 30 | Europe | Hypertonic saline, 3% saline, Furosemide Injection | Medical University of Bialystok | Nephrotic Syndrome | 01/23 | 03/23 | | |
| Completed | N/A | 150 | US | | Inova Health Care Services, National Institutes of Health (NIH), Duke University, George Mason University, University of Maryland, Baltimore, National Heart, Lung, and Blood Institute (NHLBI) | Heart Failure | 05/23 | 05/23 | | |
ChiCTR2100048459: Study on application of furosemide pump in early stage of reabsorption of critical burn |
|
|
| Not yet recruiting | N/A | 60 | | furosemide treatment ;null | Anshan Hospital of the First Hospital of China Medical University; Anshan Hospital of the First Hospital of China Medical University, self-financed | critical burn | | | | |
ChiCTR2000039912: Hydration strategy of percutaneous coronary intervention in patients with chronic heart failure and chronic kidney disease |
|
|
| Recruiting | N/A | 297 | | Hydration rate 0.5 mL/Kg/h ;Hydration rate 1 mL/Kg/h ;Hydration rate 1 mL/Kg/h + Furosemide 20 mg diuresis immediately after intervention | Department of Cardiology, The Second Hospital of Tianjin Medical University; The Second Hospital of Tianjin Medical University, Clinical Research Fund Project of The Second Hospital of Tianjin Medical University (2020LC12) | Contrast induced acute kidney injury | | | | |
NCT05599971: Intralesional Injection of Combined Digoxin and Furosemide Versus 5-Flurouracil in Plantar Warts |
|
|
| Not yet recruiting | N/A | 45 | NA | intralesional combined digoxin and furosemide, intralesional injection of 5- Fluorouracil, intralesional saline | Zagazig University | Plantar Wart | 11/23 | 02/24 | | |
MYTHOS-HF, NCT05807152: Furosemide-induced Diuresis With Matched Dehydration Compared to Standard Diuretic Therapy in Patients With Acute Heart Failure and Overt Fluid Overload |
|
|
| Recruiting | N/A | 170 | Europe | RenalGuard device | Centro Cardiologico Monzino | Acute Decompensated Heart Failure | 12/23 | 12/24 | | |
NCT05939245: Comparison of Plasma Neutrophil Gelatinase-Associated Lipocalin (pNGAL) Level in De-resuscitation With Furosemide Group and Control Group |
|
|
| Recruiting | N/A | 48 | RoW | Furosemide Injection, Placebo Injection | Indonesia University | Acute Kidney Injury Due to Sepsis | 12/23 | 06/24 | | |
NCT04733547: Spectral Analysis of Central Venous Pressure Waveform |
|
|
| Completed | N/A | 60 | RoW | Placement of a central venous catheter, Monitoring of central venous pressure, Furosemide-induced hypovolemia before graft procurement, Replacement of fluid loss after graft procurement, Monitoring of stroke volume variation | JongHae Kim | Donor Hepatectomy, Central Venous Catheter, Hypovolemia | 11/23 | 11/23 | | |
FASTR-EU, NCT06362668: EU Sites: Fluid Management of Acute Decompensated Heart Failure With Reprieve Decongestion Management System |
|
|
| Not yet recruiting | N/A | 30 | Europe | Reprieve Decongestion Management System, Diuretic (furosemide, bumetanide, torsemide, hydrochlorothiazide, and/or acetazolamide) | Reprieve Cardiovascular, Inc | Acute Decompensated Heart Failure | 10/24 | 12/24 | | |
POPS or POP02, NCT04278404: Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) |
|
|
| Recruiting | N/A | 5000 | Canada, US | The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care:, Aminocaproic acid, Amiodarone, Bosentan, Budesonide, Cefdinir, Cefepime, Ceftazidime, Clindamycin, Clobazam, Dexamethasone, Dexmedetomidine, Dextroamphetamine/Amphetamine, Fosfomycin, Furosemide, Gabapentin, Guanfacine, Hydrocortisone, Labetalol, Meropenem, Metformin, Milrinone, Nalbuphine, Nicardipine, Nifedipine, Oseltamivir, Oxycodone, Risperidone, Sertraline, Sevelamer Carbonate / Sevelamer Hydrochloride, Spironolactone, Terbutaline, Tranexamic acid, Voriconazole, Zolpidem, Azithromycin, Lopinavir/Ritonavir, Ribavirin, Tocilizumab, Anakinra, Aspirin, Canakinumab, Colchicine, Interferon, Remdesivir, Ruxolitinib, Sarilumab, Abatacept, Infliximab | Duke University, The Emmes Company, LLC, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension, Pain, Hyperphosphatemia, Primary Hyperaldosteronism, Edema, Hypokalemia, Heart Failure, Hemophilia, Menorrhagia, Insomnia, Pneumonia, Skin Infection, Arrythmia, Asthma in Children, Bronchopulmonary Dysplasia, Adrenal Insufficiency, Fibrinolysis; Hemorrhage, Attention Deficit Hyperactivity Disorder, Multisystem Inflammatory Syndrome in Children (MIS-C), Kawasaki Disease, Coagulation Disorder, Down Syndrome | 09/26 | 09/27 | | |
FOSTIK, NCT03071536: Furosemide Stress Test Predicting Early Graft Function in Kidney Transplantation |
|
|
| Recruiting | N/A | 180 | RoW | Furosemide Injection | King Chulalongkorn Memorial Hospital | Kidney Function, Kidney Transplant; Complications, Delayed Graft Function | 05/26 | 05/27 | | |
NCT05741372: A Study to Compare How Different Medicines (Rosuvastatin, Digoxin, Metformin, and Furosemide) Are Handled by the Body of Healthy People and People With Liver Cirrhosis |
|
|
| Recruiting | N/A | 30 | Europe | Rosuvastatin, Digoxin, Metformin hydrochlorid, Furosemide | Boehringer Ingelheim | Liver Cirrhosis | 01/25 | 01/25 | | |
| Recruiting | N/A | 60 | Europe | Furosemide stress test, FST | Centre Hospitalier Universitaire Vaudois | Acute Kidney Injury | 05/25 | 07/25 | | |
NCT05939193: Effect of Urine-guided Hydration on Acute Kidney Injury After CRS-HIPEC |
|
|
| Recruiting | N/A | 168 | RoW | Urine-guided hydration, Forced administration of furosemide, Routine hydration, Routine administration of furosemide | Peking University First Hospital, Aerospace Center Hospital | Cytoreductive Surgery, Hyperthermic Intraperitoneal Chemotherapy, Hydration, Diuresis, Acute Kidney Injury, Postoperative Complications | 07/24 | 01/25 | | |
NCT03511118: Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants |
|
|
| Recruiting | N/A | 1600 | Canada, US | Tranexamic acid (TXA), labetalol, metformin, nifedipine, clindamycin, oxycodone, azithromycin, escitalopram, sertraline, ondansetron, Ciprofloxacin, Doxycycline, Levofloxacin, Methylphenidate, Sumatriptan, Citalopram, Cyclobenzaprine, Furosemide, Gabapentin, Hydrochlorothiazide, Hydroxyurea, Rosuvastatin, Topiramate, Trazodone, Valganciclovir, Venlafaxine, Verapamil, Remdesivir, Anakinra, Tocilizumab, Fluvoxamine, Amoxicillin, Bupropion, Duloxetine, Hydrocodone, Levetiracetam, Paroxetine, Buprenorphine | Duke University, The Emmes Company, LLC, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Lactating Women on Select DOI, Breastfed Infants of Mothers on Select DOI | 09/24 | 09/24 | | |
NCT05129358: Testing of an Electronic Patch During Mild Dehydration |
|
|
| Completed | N/A | 31 | Europe | Dehydration, Dehydration from Furosemide, Rehydration, Rehydration by Resorb Sport | Mode Sensors AS, Oslo University Hospital | Dehydration | 11/23 | 11/23 | | |
ChiCTR2200065675: Clinical study on abdominal acupuncture in the treatment of heart and kidney yang deficiency syndrome of heart failure |
|
|
| Not yet recruiting | N/A | 84 | | Conventional drug therapy (valsartan + metoprolol succinate + spironolactone + Furosemide)+ abdominal acupuncture ;Conventional drug therapy (valsartan + metoprolol succinate + spironolactone + Furosemide) | Beijing Mentougou Hospital of Traditional Chinese Medicine; Beijing Mentougou Hospital of Traditional Chinese Medicine, Capital's Funds for Health Improvement and Research(2022-3-7061) | heart failure | | | | |
NCT06094816: Forebrain Electroneutral Transporters in Salt-sensitive Hypertension: an MRI Study |
|
|
| Recruiting | N/A | 120 | US | Furosemide (Diuretic), Lasix, Hypertonic Saline Infusion | University of Delaware, National Heart, Lung, and Blood Institute (NHLBI) | Salt-Sensitivity of Blood Pressure | 01/28 | 07/28 | | |
