| furosemide / Generic mfg. |
| Withdrawn | 4 | | US | Furosemide plus Chlorothiazide, Lasix plus Diuril, Furosemide, Lasix | Ochsner Health System | Acute Decompensated Heart Failure | 10/15 | 10/15 | | |
2008-004488-20: Ensayo clínico en fase IV, multicéntrico, controlado, aleatorizado, para evaluar la eficacia y seguridad de 3 pautas de administración de furosemida en pacientes con descompensación aguda moderada-severa de insuficiencia cardiaca crónica (Multicentric, controlled, randomized phase IV clinical trial to evaluate clinical efficacy and safety of three different dosing schedules of furosemide in patients with moderate to severe descompensation of congestive heart failure) |
|
|
| Ongoing | 4 | 105 | Europe | Solution for injection | HOSPITAL GENERAL UNIVERSITARIO DE ALICANTE | Descompensación aguda moderada-severa en pacientes con insuficiencia cardíaca congestiva (Acute moderate to severe descompensation in patients with congestive heart failure) | | | | |
2010-024175-58: Comparison of two treatment regimen of high blood pressure in patients with transplanted heart. |
|
|
| Ongoing | 4 | 40 | Europe | perindopril, losartan, furosemid, metoprolol, amlodipin, PRESTARIUM Neo, LORISTA 25, PRESTARIUM Neo Forte, LORISTA 50, LORISTA 100, PRESTARIUM Neo, LORISTA 25, PRESTARIUM Neo Forte, LORISTA 50, LORISTA 100 | IKEM, IKEM | Compensation of arterial hypertension in heart transplant recipients. Renal function and its changes in heart transplant recipients. | | | | |
2015-002585-23: The effect of saline with a high koncentration and furosemide on biomarkers of kidney damage togerther with kidney and circulatory physiology in healthy subjects. Effekten af saltvand med høj koncentration og furosemid på biomarkører for nyreskade samt nyre- og kredsløbsfysiologi hos raske forsøgspersoner. |
|
|
| Ongoing | 4 | 27 | Europe | natriumklorid/sodium chloride, Infusion, Solution for infusion, Furix | Medicinsk Forskningsafsnit, Regionshospitalet Holstebro (Department of Medical Research, Regional Hospital Holstebro), Medicinsk Forskningsafsnit, Regionshospitalet Holstebro (Department of Medical Research, Regional Hospital Holstebro) | Healthy volunteers (The effect of flurosemide, together with an infusion of hypertone saline, on the kidneys, using biomarkers) Raske forsøgspersoner (ved hjælp af biomarkører ledes efter effekten af flurosemid, under infusion af hyperton natriumklorid, på nyrerne), Healthy volunteers (The effect of the diuretic flurosemide, together with an infusion of high concentration saline, on the kidneys, using biomarkers) Raske forsøgspersoner (ved hjælp af biomarkører ledes efter effekten af det vanddrivende stof flurosemid, under infusion af saltvand med høj koncentration, på nyrerne), Body processes [G] - Physiological processes [G07] | | | | |
2008-008009-23: Estudio aleatorizado, doble ciego y controlado sobre la eficacia de la albúmina y manitol en el cebado del sistema de circulación extracorpórea en cirugÃa cardiaca para reducir el sangrado postoperatorio y las necesidades transfusionalesA randomized, double-blind, controlled trial on efficacy of priming the cardiopulmonary bypass with albumin and mannitol to reduce postoperative bleeding and transfusional requirements |
|
|
| Ongoing | 4 | 134 | Europe | human albumin, mannitol, Ringer Lactate, furosemida, human albumin, mannitol, Ringer Lactato, Seguril, human albumin, mannitol, Ringer Lactato, Seguril | Servicio de Anestesia-Reanimación | Cardiac surgery with cardiopulmonary bypass. Postoperative bleeding and requirements of blood products | | | | |
ChiCTR2000040822: Effects of low-dose furosemide combined with aminophylline on renal function in septic shock patients |
|
|
| Completed | 4 | 109 | | low-dose furosemide combined with aminophylline ;normal saline | Department of Critical Care Medicine, Affiliated Hospital of Guangdong Medical University; Hospital of Guangdong Medical University, National Nature Science Foundation of China | septic shock | | | | |
ChiCTR-IPR-17011846: The safety and effectiveness of tolvaptan in primary carcinoma of liver edema patients after undergoing partial hepatectomy |
|
|
| Not yet recruiting | 4 | 60 | | tolvaptan 15mg, once daily, for 3 days ;spironolactone 100mg, furosemide 40mg, once daily, for 3 days | Tianjin First Centre Hospital; Tianjin First Centre Hospital, Zhejiang Otsuka Pharmaceutical Co., Ltd | 术后腹水 | | | | |
PROERCAN01, NCT03195023: Effect of RAS Blockers on CKD Progression in Elderly Patients With Non Proteinuric Nephropathies |
|
|
| Recruiting | 4 | 106 | Europe | Lisinopril, Angiotensin converting enzyme inhibitors, Amlodipine, Lercanidipine, Furosemide, Thiazides | Hospital General Universitario Gregorio Marañon | Renal Insufficiency, Chronic, Proteinuria | 12/19 | 12/22 | | |
2019-004292-40: Goal directed fluid removal in critically ill patients with fluid overload. Målrettet behandling af væskeophobning hos patienter på intensiv afdeling. |
|
|
| Ongoing | 4 | 1041 | Europe | Furosemide, Infusion | Department of Anesthesia and Intensive Care Medicine, Nordsjællands hospital, Novo Nordisk Foundation, Jakob Madsens and Hustru Olga Madsens foundation | Treatment of fluid overload in critically ill adult patients in intensive care unit., Treatment of excess fluid in the body in critically ill adults admitted to an intensive care unit., Not possible to specify | | | | |
2014-003273-42: Comparing a diuretic vascular filling in the initial management of acute pulmonary embolism with right ventricular dysfunction normotensive Comparaison d’un traitement diurétique au remplissage vasculaire dans la prise en charge initiale de l’embolie pulmonaire grave normotensive avec dysfonction ventriculaire droite |
|
|
| Not yet recruiting | 4 | | Europe | Furosemid, NaCl 9% isotonic, 3400956401062, Injection, Furosémide, NaCl 9% isotonic | CHU de Nice, CHU de Nice | acute pulmonary embolism with right ventricular dysfunction normotensive Embolie pulmonaire grave normotensive avec dysfonction ventriculaire droite, acute pulmonary embolism with right ventricular dysfunction normotensive Embolie pulmonaire grave normotensive avec dysfonction ventriculaire droite, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
| Recruiting | 4 | 80 | US | Furosemide, Lasix, Torsemide, Demadex, Bumetanide, Bumex, sacubitril/valsartan, Entresto, Hydralazine, Apresoline, Isosorbide Dinitrate, Dilatrate, Isordil | Heart Center Research, LLC, Boston Scientific Corporation | Heart Failure, Congestive | 12/25 | 12/26 | | |
2021-001327-41: Withdrawal of pharmacological treatment in patients responding to cardiac resynchronization therapy: Open and randomized study Retirada de tratamiento farmacologico en pacientes respondedores a terapia de resincronización cardiaca: Estudio abierto y aleatorizado |
|
|
| Ongoing | 4 | 60 | Europe | furosemide, bisoprolol, Coated tablet, Furosemide, Bisoprolol, Eplerenone, Valsartan | Fundación para la formación e investigación sanitarias de la Región de Murcia, ISCarlos III | Heart failure Insuficiencia cardiaca, Heart failure Insuficiencia cardiaca, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
| Recruiting | 4 | 300 | Europe | Furosemide, Hydrochlorothiazide | University Hospital, Clermont-Ferrand, University Hospital, Grenoble, Hospices Civils de Lyon, Hôpital de la Croix-Rousse, CH Puy en Velay, CH Moulins-Yzeure, CH Riom, Infirmerie Protestante de Lyon, CH Issoire, CH Annecy Genevois | Heart Failure, Acute Heart Failure, Chronic Heart Failure | 12/21 | 12/21 | | |
ChiCTR1900022533: Evaluating the effect of different regimens of furosemide on edema in patients with nephrotic syndrome |
|
|
| Not yet recruiting | 4 | 60 | | Furosemide, 80mg, i.v., q.d ;Furosemide, 40mg, i.v., b.i.d | the Second Affiliated Hospital of Shantou University Medical College; the Second Affiliated Hospital of Shantou University Medical College, Funding for clinical construction of the Second Affiliated Hospital of Shantou University Medical College | Nephrotic Syndrome | | | | |
NCT05594823: Flexible vs. Fixed Diuretic Regimen in the Management of Chronic Heart Failure: A Pilot Study |
|
|
| Recruiting | 4 | 30 | Canada | Ambulatory heart failure management with Flexible Diuretic Regimen with furosemide, Ambulatory heart failure management with fixed dose furosemide | Lawson Health Research Institute | Heart Failure, Heart Diseases | 07/23 | 07/23 | | |
NCT04216784: Comparison of Diuretic Effect With Furosemide Alone Versus the Combination of Furosemide and Albumin in Cirrhotic Patients |
|
|
| Terminated | 4 | 21 | US | Furosemide Injection, Albumin Human | Rush University Medical Center | Cirrhosis, Liver, Volume Overload, Fluid Overload | 12/23 | 04/24 | | |
ChiCTR2000039724: The efficacy and safety of furosemide for prevention of intradialytic hypotension in hemodialysis patients: protocol for a multicenter randomized controlled trial |
|
|
| Not yet recruiting | 4 | 560 | | Furosemide treatment ;Blank control | Department of Nephrology, West China Hospital of Sichuan University; West China Hospital of Sichuan University, 1·3·5 project for disciplines of excellence–Clinical Research Incubation Project, West China Hospital, Sichuan University | hemodialysis | | | | |
NCT06203236: Natriuresis-Guided Diuretic Therapy in Patients With Acute Heart Failure With Reduced Ejection Fraction and Chronic Kidney Disease |
|
|
| Not yet recruiting | 4 | 300 | NA | Furosemide 20 MG, Lasix 20 MG, diuretic therapy | Assiut University | Acute Heart Failure, Chronic Kidney Diseases | 03/25 | 11/25 | | |
PAUSE-CRRT, NCT06229990: Protocol Based-furosemide Stress Test Versus Standard Care to Evaluate Renal Recovery During Continuous Renal Replacement Therapy |
|
|
| Recruiting | 4 | 40 | RoW | Furosemide Injection, Furosemide stress test | Chiang Mai University | Acute Kidney Injury | 06/24 | 06/24 | | |
| Suspended | 4 | 34 | Canada | Furosemide, Chlorthalidone | University of Alberta | End Stage Renal Disease on Dialysis | 02/25 | 02/25 | | |
DAPA-TONIC, NCT06442280: SGLT-2 Inhibitor and High-Dose Furosemide Plus Small-Volume Hypertonic Saline Solution in Acute HF |
|
|
| Not yet recruiting | 4 | 544 | NA | Dapagliflozin tablet, SGLT2 inhibitor, Hypertonic Saline Solution, 1 Ml, Hypertonic Solution, Saline, Furosemide Injection, FUROSEMIDE | University of Palermo | Heart Failure Acute, Diabetes Type 2, Heart Failure With Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction | 01/26 | 03/26 | | |
GODIF, NCT04180397: Controlled Fluid Removal in Critical Ill Patients With Fluid Overload in the Intensive Care Unit. |
|
|
| Recruiting | 4 | 1000 | Europe, RoW | Furosemide, Furix, Isotonic saline | Morten H. Bestle, University of Copenhagen, Copenhagen Trial Unit, Center for Clinical Intervention Research, Centre for Research in Intensive Care (CRIC) | Fluid Overload | 12/24 | 06/25 | | |
| Recruiting | 4 | 46 | US | Diuretic augmentation (hydrochlorothiazide, chlorthalidone, furosemide, torsemide, or bumetanide) | VA Office of Research and Development | Chronic Kidney Disease, Hypertension | 07/25 | 07/25 | | |
| Recruiting | 4 | 75 | Europe | Furosemide, Furosemide, doubled dose, Metolazone, Furosemide + Metolazone, Acetazolamide, Furosemide + Acetazolamide | Stadtspital Zürich, Ospedale Regionale di Lugano | Acute Heart Failure, Diuretic Resistance | 08/25 | 12/25 | | |
| Recruiting | 4 | 30 | US | Furosemide (plus potassium chloride), Placebo (plus placebo electrolyte solution) | Children's Hospital Medical Center, Cincinnati, Rainbow Babies and Children's Hospital, Emory University, RTI International, National Heart, Lung, and Blood Institute (NHLBI) | Bronchopulmonary Dysplasia | 09/25 | 09/25 | | |
2012-004343-80: EFFECTIVENESS OF FUROSEMIDE IN CONTINUOUS INFUSION VS ethacrynic acid IN CONTINUOUS INFUSION IN CHILDREN SUBJECT TO A heart surgery of age LESS THAN 10 YEARS Furosemide In Infusione Continua Vs Acido Etacrinico In Infusione Continua In Bambini Sottoposti A Cardiochirugia Di Eta’ Inferiore Ad 10 Anni |
|
|
| Ongoing | 3 | 100 | Europe | Solution for infusion | OSPEDALE PEDIATRICO BAMBINO GESU' DI ROMA, Ospedale Pediatrico Bambino Gesù | ALL CHILDREN AGE 'LESS THAN 10 YEARS OF AGE' WITH CONGENITAL HEART PROCEDURE SUBJECT TO cardiac surgery in whom the diuretic ARE GIVEN IN ACCORDANCE WITH THE FOLLOWING CONTINUOUS INFUSION PROTOCOL Cardiac surgery with clamping> 90 minutes Interventions interventional cardiology with hybrid approach and inotropic score> 20 after the procedure Capillary leak syndrome postoperative and / or signs of fluid overload TUTTI I BAMBINI DI ETA’ INFERIORE A 10 ANNI DI ETA’ CON CARDIOPATIA CONGENITA SOTTOPOSTI A PROCEDURA CARDIOCHIRURGICA IN CUI IL DIURETICO SIA SOMMINISTRATO IN INFUSIONE CONTINUA SECONDO IL SEGUENTE PROTOCOLLO Interventi cardiochirurgici con clampaggio >90 minuti Interventi di cardiologia interventistica con approccio ibrido e inotropic score > 20 dopo la procedura Capillary leak syndrome postoperatoria e/o segni di sovraccarico idrico, ALL CHILDREN AGE 'LESS THAN 10 YEARS OF AGE' WITH CONGENITAL HEART PROCEDURE SUBJECT TO cardiac surgery in whom the diuretic ARE GIVEN IN ACCORDANCE WITH THE FOLLOWING CONTINUOUS INFUSION P TUTTI I BAMBINI DI ETA’ INFERIORE A 10 ANNI DI ETA’ CON CARDIOPATIA CONGENITA SOTTOPOSTI A PROCEDURA CARDIOCHIRURGICA IN CUI IL DIURETICO SIA SOMMINISTRATO IN INFUSIONE CONTINUA SECONDO IL, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
| Not yet recruiting | 3 | 88 | Europe | Furosémide Renaudin, Chlorure de sodium 0,9%, Solution for injection, Solution for infusion, Furosémide Renaudin, Chlorure de sodium 0,9% | ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP), Fondation Coeur & Recherche | Myocardial infarction with right ventricular extension. Patients ayant un infarctusv inférieur avec extension au ventricule droit, NA NA, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
2016-003014-28: Immunosuppression in human negative virus myocarditis Immunosoppressione nella miocardite umana virus negativa |
|
|
| Ongoing | 3 | 92 | Europe | prednisone, AZATIOPRINA, Enapren, LANOXIN, Lasix, DILATREND, [na], [NA], Tablet, Film-coated tablet, DELTACORTENE - 25 MG COMPRESSE 10 COMPRESSE, AZATIOPRINA ASPEN - 50 MG COMPRESSE RIVESTITE CON FILM 50 COMPRESSE, ENAPREN - 5 MG COMPRESSE 28 COMPRESSE, LANOXIN - 0.125 MG COMPRESSE 1 BLISTER DA 30 COMPRESSE, LASIX - 25 MG COMPRESSE30 COMPRESSE, DILATREND - 6.25 MG COMPRESSE 56 COMPRESSE | UMBERTO I - POLICLINICO DI ROMA, AIFA - Italian Medicines Agency | virus negative inflammatory cardiomyopathy cardiomiopatia infiammatoria virus negativa, Inflammation of the hearth not virus-induced Infiammazione del cuore non dovuta a virus, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
2019-002607-18: Clinical study on the efficacy of amiloride for the treatment of edema in nephrotic syndrome Klinische Studie über die Wirksamkeit von Amilorid zur Behandlung der Ödeme beim nephrotischen Syndrom |
|
|
| Not yet recruiting | 3 | 36 | Europe | Furosemid-ratiopharm® 40 mgTabletten, Tablet, Modamide 5 mg tablet, Furosemid-ratiopharm® 40 mg Tabletten | University Hospital Tuebingen, Faculty of Medicine University of Tübingen | Nephrotic syndrome Nephrotisches Syndrom, Nephrotic syndrome Nephrotisches Syndrom, Diseases [C] - Symptoms and general pathology [C23] | | | | |
NCT05105009: Furosemide and Creatinine Tubular Stress Test in Order to Measure Proximal Tubule Residual Function |
|
|
| Recruiting | 3 | 72 | RoW | Furosemide, Creatinine | Instituto Nacional de Cardiologia Ignacio Chavez | Chronic Kidney Failure | 12/21 | 07/22 | | |
NCT05270421: Effect of Furosemide on ESWL Outcomes for Renal and Ureteral Calculi |
|
|
| Recruiting | 3 | 500 | RoW | Furosemide 40 mg, Conventional Treatment | Shiraz University of Medical Sciences | Urolithiasis, Nephrolithiasis, Urinary Calculi, Ureterolithiasis | 03/22 | 07/22 | | |
NEB-HF, NCT04465123: Early Sequential Nephron Blockade in Acute Heart Failure Patients: A Randomised, Controlled Study |
|
|
| Recruiting | 3 | 100 | RoW | Spironolactone or hydrochlorothiazide, Aldactone, HCTZ, Thiazide, Placebo | Chiang Mai University | Acute Heart Failure, Acute Kidney Injury | 07/22 | 12/22 | | |
| Terminated | 3 | 20 | Europe | Amiloride, Furosemide | University Hospital Tuebingen | Nephrotic Syndrome, Edema, Sodium Retention | 11/22 | 11/22 | | |
NCT05620784: Intra-operative Loop Diuretics to Improve Same-day Discharge Rates After HoLEP |
|
|
| Recruiting | 3 | 138 | US | Furosemide, Lasix, Loop diuretic | Northwestern University | BPH With Urinary Obstruction, BPH, Hematuria, Same Day Discharge | 06/23 | 08/24 | | |
TFO, NCT05093621: Torsemide Comparison With Furosemide for Management of Patients With Stable Heart Failure |
|
|
| Active, not recruiting | 3 | 125 | US | Furosemide, Torsemide | Yale University | Heart Failure | 06/23 | 08/24 | | |
| Not yet recruiting | 3 | 200 | NA | Furosemide, Lasix, Diuretic, Normal saline | American University of Beirut Medical Center | Chronic Obstructive Pulmonary Disease Exacerbation, COPD Exacerbation | 12/24 | 12/24 | | |
NCT06407401: Improvement of Quality of Life Through Supportive Treatments for Hormone Therapy - Related Symptoms in Women With Early Breast Cancer |
|
|
| Not yet recruiting | 3 | 399 | NA | Duloxetine 60 MG, Furosemide 40 mg, Booklet for healthy behaviors | European Organisation for Research and Treatment of Cancer - EORTC | ER+ Breast Cancer, HER2-negative Breast Cancer, Breast Cancer Stage I, Breast Cancer Stage II, Breast Cancer Stage III, Drug-Related Side Effects and Adverse Reactions, Musculoskeletal Pain | 04/28 | 11/28 | | |
FIRE Stones, NCT05916963: Impact of Forced Diuresis on the Residual Fragment Rate After Flexible Ureteroscopy for Destruction of Kidney Stones With Laser |
|
|
| Not yet recruiting | 3 | 374 | NA | Furosemide 40 mg | University Hospital, Tours | Kidney Stone | 03/26 | 03/26 | | |
| Terminated | 2/3 | 40 | Canada | Nebulized Furosemide, Nebulized Saline | Dr. John Muscedere, University Health Network, Toronto | Covid19, Respiratory Failure | 02/23 | 04/23 | | |
NCT05933642: Diuretic Efficacy of Aminophylline and Furosemide Combination vs Furosemide Alone in Critically Ill Adults |
|
|
| Recruiting | 2/3 | 132 | RoW | Aminophylline, Frusemide, Lasix | University of Malaya | Acute Kidney Injury | 12/23 | 12/23 | | |
INFURO, NCT06252454: The Impact of Inhaled Furosemide and Perorally Administered Levodropropizine on Dyspnea in Patients With Respiratory Diseases |
|
|
| Recruiting | 2/3 | 102 | RoW | Furosemide 40 mg, Levodropropizine, Levopront, Placebo - saline | University Hospital Hradec Kralove, Masaryk University | Dyspnea | 12/24 | 12/25 | | |
| Ongoing | 2 | 32 | Europe | Ionic Contra-Viral Therapy (ICVT) comprised of digoxin and furosemide, CLS003, Gel | Cutanea Life Sciences, Cutanea Life Sciences | Actinic keratosis, Actinic keratosis, Diseases [C] - Skin and Connective Tissue Diseases [C17] | | | | |
2016-000870-39: Digoxin / Furosemide topical therapy for genital warts and VIN lesions of immunocompromised and immunocompetent patients |
|
|
| Not yet recruiting | 2 | 48 | Europe | Ionic Contra-Viral Therapy (ICVT) comprised of digoxin and furosemide, CLS003, Gel | Cutanea Life Sciences, Cutanea Life Science | HPV-induced genital lesions of immunocompromised and immunocompetent patients, Genital warts or Vulval HSIL, Diseases [C] - Skin and Connective Tissue Diseases [C17] | | | | |
2018-000970-31: A study designed to evaluate the effects of BMS-986231 versus placebo on urine output when taken with a single dose of a diuretic (furosemide). BMS-986231 or Placebo are provided in the form of Intravenous Infusions for a duration of 8 hours, with furosemide given after 4 hours, in patients whose heart is unable to pump sufficiently (chronic heart failure); exposed to each of the 2 interventions over the course of the study. |
|
|
| Not yet recruiting | 2 | 20 | Europe | BMS-986231-01 for Injection, 240 mg/vial, BMS-986231, Powder for concentrate for solution for infusion | Bristol-Myers Squibb International Corporation, Bristol-Myers Squibb International Corporation | Heart failure with reduced ejection fraction (HFrEF), Inability of the heart to pump sufficiently to maintain blood flow to meet the body's needs., Diseases [C] - Cardiovascular Diseases [C14] | | | | |
NCT04496596: Study of Suramin in Subjects With Furosemide-Resistant AKI |
|
|
| Active, not recruiting | 2 | 68 | US | Suramin, Placebo | Rediscovery Life Sciences | Acute Kidney Injury | 04/23 | 12/23 | | |
NCT05255159: Lesion-to-lesion Comparison of 68Ga-HA-DOTATATE, 18F-DOPA, and 18F-FDG PET/CT in the Evaluation of Metastatic Neuroendocrine Tumors |
|
|
| Recruiting | 2 | 50 | Canada | 18F-DOPA with furosemide | University of Alberta | Neuroendocrine Tumors | 12/24 | 12/24 | | |
| Recruiting | 2 | 60 | RoW | conventional treatment, conventional treatment ( anti diabetic drugs and antihyperlipidimic drugs ), Furosemide or other alternatives , Niaspan or other alternatives, conventional therapy, Trimetazidine, furosemide or other alternative , niaspan or other alternative | October 6 University | Non-Alcoholic Fatty Liver Disease | 06/24 | 09/25 | | |
NCT06036914: A Study of Ultra High Dose Diuretics to Treat Heart Failure |
|
|
| Enrolling by invitation | 2 | 20 | US | Bumetanide, Ultra-high dose diuretic, Furosemide, Standard dose diuretic | Mayo Clinic | Heart Failure; With Decompensation | 08/24 | 08/24 | | |
NCT05779943: Comparison of 18F-rhPSMA-7.3 PET/CT With and Without Furosemide in Biochemical Recurrence of Prostate Cancer |
|
|
| Active, not recruiting | 2 | 20 | US | Furosemide, 54-31-9, FRS, Furosemide, FUROSEMIDE, Lasix, Lasix, LB 502, LB-502, LB-502, SK-Furosemide, F18-rhPSMA-7.3, (18F)-rhPSMA-7.3,18F-rhPSMA-7.3,18FrhPSMA-7.3,2305081-64-3,F-18-rhPSMA-7.3,FLOTUFOLASTAT F-18, Fluorine F18 radiohybrid PSMA-7.3, Fluorine F18 rhPSMA-7.3, Fluorine-18 rhPSMA-7.3, rhPSMA-7.3(18F), Positron Emission Tomography, Medical Imaging,Positron Emission Tomography, PET, PET SCAN, Computed Tomography, CAT, CAT Scan, CAT scan, CAT Scan,Computed Axial Tomography,Computed Tomography, Computerized Axial Tomography | Emory University, National Cancer Institute (NCI), Blue Earth Diagnostics | Prostate Adenocarcinoma, Recurrent Prostate Carcinoma | 07/27 | 07/28 | | |
NCT01756677: Low Dose Cytarabine and Lintuzumab-Ac225 in Older Patients |
|
|
| Active, not recruiting | 1/2 | 24 | US | Cytarabine, Cytosar, Ara-C, DepoCyt, Cytosine arabinosine hydrochloride, Low dose Ara-C, LDAC, Lintuzumab-Ac225, Lintuzumab, Lasix, furosemide, Spironolactone | M.D. Anderson Cancer Center, Actinium Pharmaceuticals | Leukemia | 10/16 | | | |
|
|
NCT06024889: Acute Effects of Furosemide on Hemodynamics and Pulmonary Congestion in Acute Decompensated Heart Failure. |
|
|
| Completed | 1/2 | 20 | Europe | Furosemide Injection | Johannes Grand | Acute Heart Failure | 02/24 | 02/24 | | |
| Recruiting | 1/2 | 20 | US | Furosemide 40 mg, Lasix | Vanderbilt University Medical Center | High Blood Pressure, Salt; Excess, Inflammation | 09/25 | 09/25 | | |
| Not yet recruiting | 1/2 | 84 | Europe | PolyCore (Polydextrin, L-Carnitine, D-xylitol), PolyCore peritoneal dialysis solution | Iperboreal Pharma Srl | Congestive Heart Failure | 11/25 | 03/26 | | |
ChiCTR-TRC-12002146: Whether the loop diuretic could cause or worse nephrotic syndrome to get acute tubular injury? |
|
|
| Completed | 1 | 60 | | Given furosemide treatment ;Not given furosemide treatment | the Affiliated Hospital of Guangdong Medical College; Level of the institution：, Self support | nephrotic syndrome | | | | |
NCT05768360: A Study to Assess the Effects of Savolitinib on the Pharmacokinetics of Digoxin, Rosuvastatin, Metformin, and Furosemide in Healthy Male Subjects |
|
|
| Completed | 1 | 6 | Europe | Savolitinib, Digoxin, Metformin Hydrochloride, Rosuvastatin, Furosemide | AstraZeneca, Parexel | Healthy Male Subjects | 06/23 | 06/23 | | |
NCT05365451: Pharmacokinetic Drug-Drug Interaction Study to Identify Biomarkers of Kidney Transporters |
|
|
| Completed | 1 | 32 | US | MetFORMIN Oral Solution, Riomet, Cimetidine 400 MG, Tagamet, Furosemide Oral Liquid Product, Lasix, Probenecid 500 MG, Probalan | Washington State University, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH) | Interaction, Endogenous Biomarkers | 07/23 | 07/23 | | |
NCT05981365: Voxelotor CYP and Transporter Cocktail Interaction Study |
|
|
| Completed | 1 | 44 | US | Voxelotor, Oxbryta, Bupropion, Wellbutrin, Repaglinide, Prandin, Flurbiprofen, Ansaid, Omeprazole, Prilosec, Midazolam, Dormicum, Metformin, Glucophage, Furosemide, Lasix, Rosuvastatin, Crestor | Pfizer | Sickle Cell Disease | 10/23 | 10/23 | | |
NCT06105255: A Study to Evaluate the Effects of D-1553 on PK of Midazolam, Caffeine, Rosuvastatin, Furosemide, Digoxin, and Itraconazole or Omeprazole on PK of D-1553 |
|
|
| Active, not recruiting | 1 | 44 | RoW | D-1553, other | InventisBio Co., Ltd | Healthy Male | 03/24 | 07/24 | | |
NCT05098366: Furosemide Use to Fill the Bladder of Pediatric Females Awaiting Pelvic Ultrasound |
|
|
| Completed | 1 | 42 | US | Furosemide, Lasix, Normal saline, Intravenous fluids, IV fluids | Connecticut Children's Medical Center | Ovarian Torsion | 12/23 | 12/23 | | |
NCT06167707: Pharmacokinetics and Pharmacodynamics of Subcutaneous vs Intravenous Furosemide in Healthy Volunteers |
|
|
| Completed | 1 | 21 | US | SCP-111, Furosemide USP | scPharmaceuticals, Inc. | Heart Failure, Fluid Overload | 06/24 | 06/24 | | |
NCT05470283: Phase I, Open-Label, Study of Tumor Infiltrating Lymphocytes Engineered With Membrane Bound IL15 Plus Acetazolamide in Adult Patients With Metastatic Melanoma |
|
|
| Active, not recruiting | 1 | 21 | US | OBX-115, Acetazolamide, Cyclophosphamide, Cytoxan®, Neosar, Furosemide, Mesna, Fludarabine Phosphate, Fludarabine, Fludara | M.D. Anderson Cancer Center | Tumor, Metastatic Melanoma, Melanoma | 04/27 | 04/27 | | |
ChiCTR-IOR-14005250: Left Ventricular End-Diastolic Pressure and Brain Natriuretic Peptide Guided Low-Dose Furosemide for Preventing Contrast-induced Nephropathy in the Percutaneous Coronary Intervention |
|
|
| Recruiting | N/A | 1140 | | hydration + furosemide ;hydration + apply furosemide Individually | The Second Hospital of Hebei Medical University; Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Troditional and Chinese Medicine, The project of Hebei Provincial Health Department | Contrast-induced Nephropathy | | | | |
ChiCTR1800017270: Exploration of recombinant hypertonic saline combined with furosemide in the treatment of heart failure |
|
|
| Recruiting | N/A | 522 | | C-HSS (100ml) combined with furosemide (40mg) ;furosemide (40mg) | Cangzhou Central Hospital; Cangzhou Central Hospital, no | heart failure | | | | |
ChiCTR-EOC-16009980: A cohort study on salt sensitivity of blood pressure related genes and environmental risk factors survey and construction of risk prediction model |
|
|
| Recruiting | N/A | 1950 | | Modified Sullivan acute oral saline load and furosemide sodium excretion volume reduction test ;Modified Sullivan acute oral saline load and furosemide sodium excretion volume reduction test | Capital Medical University; Capital Medical University, National Natural Science Foundation of China | Hypertension | | | | |
| Recruiting | N/A | 60 | | Rrestricted fluid ;Open fluid input and furosemide are given ;Goal-directed fluid therapy | Department of Anesthesiology, Shengjing Hospital, China Medical University; Shengjing Hospital, China Medical University, No | Colorectal Cancer | | | | |
ChiCTR1800017639: A randomized controlled trial for perioperative administration of tolvaptan in improving postoperative recovery in patients with cirrhosis |
|
|
| Recruiting | N/A | 240 | | Tolvaptan + Furosemide ;Furosemide | Shanghai Public Health Clinical Center; Shanghai Public Health Clinical Center, self-financing | liver cirrhosis | | | | |
ChiCTR1800014902: Dehydration treatment and renal protection of older patients with acute decompensated heart failure (simple loop diuretics vs combined multi-target diuretics): a prospective randomized controlled study |
|
|
| Not yet recruiting | N/A | 200 | | furosemide+ AVP-V2A+rhBNP ;simple loop diuretics | Chinese PLA General Hospital; Chinese PLA General Hospital, Open fund from national center of clinical medical research on geriatric diseases | acute decompensated heart failure | | | | |
NCT04182854: Use of Diuretics in Maintenance Hemodialysis Patients Undergoing Bioimpedance-guided Fluid Management |
|
|
| Recruiting | N/A | 46 | RoW | Furosemid hydrochlorothiazide | Capital Medical University | Diuretic Abuse | 02/20 | 07/21 | | |
ChiCTR1800015215: Comparison of Usefulness of furosemide and budesonide Nebulizations for Attenuating Postoperative Sore Throat |
|
|
| Recruiting | N/A | 81 | | aerosol inhalation of furosemide 40mg ;aerosol inhalation of budesonide 2mg ;0.9% N.S | Plastic Surgery Hospital, The Chinese Academy of Medical Sciences, Peking Union Medical College; Plastic Surgery Hospital, The Chinese Academy of Medical Sciences, Peking Union Medical College, Self -funding | Postoperative Sore Throat | | | | |
NCT04156451: Effect of Fluid Deresuscitation With Central Venous Pressure Target 0-4 mmHg in Septic Shock Patients |
|
|
| Recruiting | N/A | 44 | RoW | Fluid resuscitation and furosemide administration (bolus and continuous) with central venous pressure target 8 - 10 mmHg, Fluid deresuscitation and furosemide administration (bolus and continuous) with central venous pressure target 0 - 4 mmHg | Indonesia University | Septic Shock | 09/20 | 11/20 | | |
ChiCTR1900021724: Prevention of contrast-induced acute kidney injury by furosemide with standard hydration in high risk patients undergoing coronary interventional procedures: A randomized controlled trial |
|
|
| Not yet recruiting | N/A | 230 | | Continuous intravenous infusion of furosemide was performed at 0.2-0.5mg/kg for 24 hours after coronary interventional procedures ;Continuous intravenous infusion of Normal saline was performed at 1-1.5ml/kg /h for 12 hours before operation and 24 hours after operation | Zhongda Hospital of Southeast University; Zhongda Hospital of Southeast University, Self-financing | Contast-induced Acute Kidney Injury | | | | |
ChiCTR1900023793: A study for prevention and treatment of complications associated with fluid extravasation during shoulder arthroscopy by perioperative intervention |
|
|
| Not yet recruiting | N/A | 180 | | furosemide ;methylprednisolone ;ulinastatin ;saline ;furosemide+ methylprednisolone ;furosemide+ulinastatin | Sichuan Provincial Orthopedic Hospital; Sichuan Provincial Orthopedic Hospital, Health and Family Planning Commission of Sichuan Province | Complications associated with fluid extravasation during shoulder arthroscopy | | | | |
ChiCTR1900022989: A prospective, randomized, controlled trial for mirilone for controlled low central venous pressure in hepatectomy |
|
|
| Recruiting | N/A | 90 | | R-L ml/kg/h + lasix 10mg/time ;glycerin 0.1-0.6ug/kg/min ;mirilone0.5ug/kg/min | the First Affiliated Hospital of Sun Yatsen University; the First Affiliated Hospital of Sun Yatsen University, self-funded | hepatectomy | | | | |
ChiCTR2000041236: Prevention and treatment of complications associated with fluid extravasation during shoulder arthroscopy: a randomized controlled double-blind trial |
|
|
| Recruiting | N/A | 90 | | furosemide ;methylprednisolone ;saline | Sichuan Provincial Orthopedic Hospital; Sichuan Provincial Orthopedic Hospital, Sichuan and Technology Department of Sichuan Province | Complications associated with fluid extravasation during shoulder arthroscopy | | | | |
ChiCTR2000031981: Predictive value of furosemide stress test combined with biomarker detection in children with acute renal injury |
|
|
| Recruiting | N/A | | | | The First Affiliated Hospital of Sun Yat-Sen University; The First Affiliated Hospital of Sun Yat-Sen University, self-raised | acute kidney injury | | | | |
NCT01275729: The Effect of Loop Diuretics on Severity and Outcome of Acute Kidney Injury |
|
|
| Completed | N/A | 96 | US | Furosemide, Laisx | University of Chicago | Acute Kidney Failure | 06/22 | 06/22 | | |
Lunar OI, NCT06467825: Effect of Sex on Orthostatic Intolerance and Cardiovascular Response During Lunar Descent and Ascent |
|
|
| Recruiting | N/A | 38 | US | Potassium Supplement, Furosemide 20 MG, Lasix, Compression Garment | National Aeronautics and Space Administration (NASA) | Healthy | 09/25 | 09/25 | | |
NCT05520658: Evaluation of the Efficacy of Intralesional Injection of Combined Digoxin and Furosemide Versus 5 - Fluorouracil in Treatment of Plantar Warts |
|
|
| Recruiting | N/A | 60 | RoW | combined digoxin and furosemide, 5 fluorouracil | Sohag University | Plantar Wart | 09/22 | 09/22 | | |
NCT05569655: Efficacy and Safety Evaluation of Tolvaptan in the Treatment of Patients With RHF Caused by PAH |
|
|
| Recruiting | N/A | 100 | RoW | Tolvaptan, Samsca, Furosemide, LASâ…¨ | Chinese Pulmonary Vascular Disease Research Group | Pulmonary Arterial Hypertension, Randomized Controlled Trial | 11/22 | 12/22 | | |
NCT05379257: A Feasibility Non-inferiority Clinical Trial for Dosing of Diuretics in CHF Patients |
|
|
| Recruiting | N/A | 12 | RoW | Random dosage and time of furosemide | Hadassah Medical Organization | Congestive Heart Failure | 12/22 | 12/22 | | |
ChiCTR2000033400: Canceled by the investigator Comparison of Usefulness of furosemide and physiological saline Nebulizations for Attenuating Postoperative Sore Throat |
|
|
| Suspended | N/A | 100 | | inhale furosemide ;inhale physiological saline | Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College; Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Self -funding | Postoperative Sore Throat | | | | |
FLUSH-NS, NCT03750136: Furosemide Alone or Unexpectedly With Solution of Hypertonic Saline in Nephrotic Syndrome |
|
|
| Recruiting | N/A | 30 | Europe | Hypertonic saline, 3% saline, Furosemide Injection | Medical University of Bialystok | Nephrotic Syndrome | 01/23 | 03/23 | | |
| Completed | N/A | 150 | US | | Inova Health Care Services, National Institutes of Health (NIH), Duke University, George Mason University, University of Maryland, Baltimore, National Heart, Lung, and Blood Institute (NHLBI) | Heart Failure | 05/23 | 05/23 | | |
ChiCTR2100048459: Study on application of furosemide pump in early stage of reabsorption of critical burn |
|
|
| Not yet recruiting | N/A | 60 | | furosemide treatment ;null | Anshan Hospital of the First Hospital of China Medical University; Anshan Hospital of the First Hospital of China Medical University, self-financed | critical burn | | | | |
ChiCTR2000039912: Hydration strategy of percutaneous coronary intervention in patients with chronic heart failure and chronic kidney disease |
|
|
| Recruiting | N/A | 297 | | Hydration rate 0.5 mL/Kg/h ;Hydration rate 1 mL/Kg/h ;Hydration rate 1 mL/Kg/h + Furosemide 20 mg diuresis immediately after intervention | Department of Cardiology, The Second Hospital of Tianjin Medical University; The Second Hospital of Tianjin Medical University, Clinical Research Fund Project of The Second Hospital of Tianjin Medical University (2020LC12) | Contrast induced acute kidney injury | | | | |
NCT05599971: Intralesional Injection of Combined Digoxin and Furosemide Versus 5-Flurouracil in Plantar Warts |
|
|
| Not yet recruiting | N/A | 45 | NA | intralesional combined digoxin and furosemide, intralesional injection of 5- Fluorouracil, intralesional saline | Zagazig University | Plantar Wart | 11/23 | 02/24 | | |
MYTHOS-HF, NCT05807152: Furosemide-induced Diuresis With Matched Dehydration Compared to Standard Diuretic Therapy in Patients With Acute Heart Failure and Overt Fluid Overload |
|
|
| Recruiting | N/A | 170 | Europe | RenalGuard device | Centro Cardiologico Monzino | Acute Decompensated Heart Failure | 12/23 | 12/24 | | |
NCT05939245: Comparison of Plasma Neutrophil Gelatinase-Associated Lipocalin (pNGAL) Level in De-resuscitation With Furosemide Group and Control Group |
|
|
| Recruiting | N/A | 48 | RoW | Furosemide Injection, Placebo Injection | Indonesia University | Acute Kidney Injury Due to Sepsis | 12/23 | 06/24 | | |
NCT04733547: Spectral Analysis of Central Venous Pressure Waveform |
|
|
| Completed | N/A | 60 | RoW | Placement of a central venous catheter, Monitoring of central venous pressure, Furosemide-induced hypovolemia before graft procurement, Replacement of fluid loss after graft procurement, Monitoring of stroke volume variation | JongHae Kim | Donor Hepatectomy, Central Venous Catheter, Hypovolemia | 11/23 | 11/23 | | |
POPS or POP02, NCT04278404: Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) |
|
|
| Recruiting | N/A | 5000 | Canada, US | The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care:, Aminocaproic acid, Amiodarone, Bosentan, Budesonide, Cefdinir, Cefepime, Ceftazidime, Clindamycin, Clobazam, Dexamethasone, Dexmedetomidine, Dextroamphetamine/Amphetamine, Fosfomycin, Furosemide, Gabapentin, Guanfacine, Hydrocortisone, Labetalol, Meropenem, Metformin, Milrinone, Nalbuphine, Nicardipine, Nifedipine, Oseltamivir, Oxycodone, Risperidone, Sertraline, Sevelamer Carbonate / Sevelamer Hydrochloride, Spironolactone, Terbutaline, Tranexamic acid, Voriconazole, Zolpidem, Azithromycin, Lopinavir/Ritonavir, Ribavirin, Tocilizumab, Anakinra, Aspirin, Canakinumab, Colchicine, Interferon, Remdesivir, Ruxolitinib, Sarilumab, Abatacept, Infliximab | Duke University, The Emmes Company, LLC, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension, Pain, Hyperphosphatemia, Primary Hyperaldosteronism, Edema, Hypokalemia, Heart Failure, Hemophilia, Menorrhagia, Insomnia, Pneumonia, Skin Infection, Arrythmia, Asthma in Children, Bronchopulmonary Dysplasia, Adrenal Insufficiency, Fibrinolysis; Hemorrhage, Attention Deficit Hyperactivity Disorder, Multisystem Inflammatory Syndrome in Children (MIS-C), Kawasaki Disease, Coagulation Disorder, Down Syndrome | 09/26 | 09/27 | | |
FOSTIK, NCT03071536: Furosemide Stress Test Predicting Early Graft Function in Kidney Transplantation |
|
|
| Recruiting | N/A | 180 | RoW | Furosemide Injection | King Chulalongkorn Memorial Hospital | Kidney Function, Kidney Transplant; Complications, Delayed Graft Function | 05/26 | 05/27 | | |
FASTR-EU, NCT06362668: EU Sites: Fluid Management of Acute Decompensated Heart Failure With Reprieve Decongestion Management System |
|
|
| Recruiting | N/A | 30 | Europe | Reprieve Decongestion Management System, Diuretic (furosemide, bumetanide, torsemide, hydrochlorothiazide, and/or acetazolamide) | Reprieve Cardiovascular, Inc | Acute Decompensated Heart Failure | 10/24 | 12/24 | | |
NCT05741372: A Study to Compare How Different Medicines (Rosuvastatin, Digoxin, Metformin, and Furosemide) Are Handled by the Body of Healthy People and People With Liver Cirrhosis |
|
|
| Recruiting | N/A | 30 | Europe | Rosuvastatin, Digoxin, Metformin hydrochlorid, Furosemide | Boehringer Ingelheim | Liver Cirrhosis | 01/25 | 01/25 | | |
| Recruiting | N/A | 60 | Europe | Furosemide stress test, FST | Centre Hospitalier Universitaire Vaudois | Acute Kidney Injury | 05/25 | 07/25 | | |
NCT05939193: Effect of Urine-guided Hydration on Acute Kidney Injury After CRS-HIPEC |
|
|
| Recruiting | N/A | 168 | RoW | Urine-guided hydration, Forced administration of furosemide, Routine hydration, Routine administration of furosemide | Peking University First Hospital, Aerospace Center Hospital | Cytoreductive Surgery, Hyperthermic Intraperitoneal Chemotherapy, Hydration, Diuresis, Acute Kidney Injury, Postoperative Complications | 07/24 | 01/25 | | |
NCT03511118: Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants |
|
|
| Recruiting | N/A | 1600 | Canada, US | Tranexamic acid (TXA), labetalol, metformin, nifedipine, clindamycin, oxycodone, azithromycin, escitalopram, sertraline, ondansetron, Ciprofloxacin, Doxycycline, Levofloxacin, Methylphenidate, Sumatriptan, Citalopram, Cyclobenzaprine, Furosemide, Gabapentin, Hydrochlorothiazide, Hydroxyurea, Rosuvastatin, Topiramate, Trazodone, Valganciclovir, Venlafaxine, Verapamil, Remdesivir, Anakinra, Tocilizumab, Fluvoxamine, Amoxicillin, Bupropion, Duloxetine, Hydrocodone, Levetiracetam, Paroxetine, Buprenorphine | Duke University, The Emmes Company, LLC, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Lactating Women on Select DOI, Breastfed Infants of Mothers on Select DOI | 09/24 | 09/24 | | |
NCT05129358: Testing of an Electronic Patch During Mild Dehydration |
|
|
| Completed | N/A | 31 | Europe | Dehydration, Dehydration from Furosemide, Rehydration, Rehydration by Resorb Sport | Mode Sensors AS, Oslo University Hospital | Dehydration | 11/23 | 11/23 | | |
ChiCTR2200065675: Clinical study on abdominal acupuncture in the treatment of heart and kidney yang deficiency syndrome of heart failure |
|
|
| Not yet recruiting | N/A | 84 | | Conventional drug therapy (valsartan + metoprolol succinate + spironolactone + Furosemide)+ abdominal acupuncture ;Conventional drug therapy (valsartan + metoprolol succinate + spironolactone + Furosemide) | Beijing Mentougou Hospital of Traditional Chinese Medicine; Beijing Mentougou Hospital of Traditional Chinese Medicine, Capital's Funds for Health Improvement and Research(2022-3-7061) | heart failure | | | | |
NCT06094816: Forebrain Electroneutral Transporters in Salt-sensitive Hypertension: an MRI Study |
|
|
| Recruiting | N/A | 120 | US | Furosemide (Diuretic), Lasix, Hypertonic Saline Infusion | University of Delaware, National Heart, Lung, and Blood Institute (NHLBI) | Salt-Sensitivity of Blood Pressure | 01/28 | 07/28 | | |
NCT04464811: Furosemide Stress Test for the Prediction of Acute Kidney Injury Severity in Acute Heart Failure Patients |
|
|
| Recruiting | N/A | 257 | RoW | Furosemide stress test | Chiang Mai University | Heart Failure, Acute Kidney Injury | 08/21 | 08/21 | | |