| furosemide / Generic mfg. |
NCT00652652: Evaluation of Combined Action Between Natrecor and Furosemide on Kidney and Neurohormone Responses in Chronic Heart Failure: A Phase-IV study704.351 / DSS |
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| Completed | 4 | | US | nesiritide, furosemide | Scios, Inc. | Congestive Heart Failure, Chronic Heart Failure | | 01/04 | | |
NCT00663195: Effects of Spironolactone on Matrix Metalloproteinases (MMPs) in Heart Failure |
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| Completed | 4 | 16 | Japan | spironolactone + furosemide | Tottori University Hospital | Chronic Stable Heart Failure | | 12/05 | | |
NCT00664222: Spironolactone and Insulin Resistance in Chronic Heart Failure (CHF) |
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| Completed | 4 | 16 | Japan | spironolactone + furosemide | Tottori University Hospital | Chronic Stable Heart Failure | | 12/05 | | |
NCT00115726: Trial Assessing the Effect of Preoperative Furosemide on Intraoperative Blood Pressure |
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| Completed | 4 | 198 | US, Canada | furosemide, placebo | University of Calgary, The Centre for the Advancement of Health | Hypertension, Hypotension, Edema, Congestive Heart Failure | 02/06 | 04/07 | | |
| Completed | 4 | 40 | Europe | Furosemide | University of Campania "Luigi Vanvitelli" | Chronic Kidney Disease | 05/08 | 07/08 | | |
| Completed | 4 | 100 | Europe | Spironolactone and furosemide | University of Padova | Cirrhosis, Ascites | 09/08 | 09/08 | | |
NCT00690521: A Comparison of Hydrochlorothiazide and Metolazone in Combination With Furosemide in Congestive Heart Failure Patients |
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| Unknown status | 4 | 13 | US | metolazone or hydrochlorothiazide | University of New Mexico | Congestive Heart Failure | 01/09 | 01/09 | | |
NCT00421863: Italian Study on the Cardiovascular Effects of Systolic Blood Pressure Control - CARDIOSIS Study |
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| Completed | 4 | 1111 | Europe | Triatec 10 mg, Triatec HCT 5, Lasix 25, Micardis 80 mg, Micardis plus 80/12.5, Catapresan TTS 2, Norvasc 10 mg, Triatec 5 mg, Pluscor | Heart Care Foundation | Hypertension | 01/09 | 01/09 | | |
| Completed | 4 | 142 | Europe | Torasemide Prolonged Release, Torasemide Prolonged release:Sutril neo, Furosemide, Furosemide: Seguril | Ferrer Internacional S.A. | Congestive Heart Failure | 06/09 | 06/09 | | |
| Unknown status | 4 | 300 | Europe | Furosemide, low-dose dopamine + low-dose furosemide | Larissa University Hospital | Acute Heart Failure | 01/10 | 07/12 | | |
NCT00806910: Diuretic and Renal Effects of Vaprisol When Administered Along With Furosemide and Nesiritide Continuous Infusion |
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| Withdrawn | 4 | 0 | US | Conivaptan, Vaprisol, Placebo, Saline | Albert Einstein Healthcare Network, Astellas Pharma Inc | Heart Failure | 02/10 | 02/10 | | |
| Completed | 4 | 320 | Japan | furosemide, Lasix, azosemide, Daiart | Hyogo College of Medicine, Ministry of Health, Labour and Welfare, Japan | Congestive Heart Failure | 08/10 | 08/10 | | |
NCT01073189: Intra-Renal Therapy of Diuretic Unresponsive Acute Kidney Injury |
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| Withdrawn | 4 | 0 | US | Intra-Renal Fenoldopam, Angiodynamics Benefit Catheter, Fenoldopam mesylate, Furosemide, Lasix | Southeast Renal Research Institute | Kidney Failures, Acute | 01/11 | 01/11 | | |
| Terminated | 4 | 10 | Europe | Furosemide or Furosemide and Dopamine, Ultrafiltration | Niguarda Hospital, Associazione Nazionale Medici Cardiologi Ospedalieri | Acute Decompensated Heart Failure | 06/11 | 04/17 | | |
| Completed | 4 | 60 | Europe | Furosemide, diuretics | University of Palermo | ADHF | 09/11 | 09/11 | | |
ACTRN12611000480987: Combination of furosemide and albumin for treatment of edema in chronic kidney disease patients |
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| Completed | 4 | 22 | | | Ramathibodi research fund, Ramathibodi research fund | Edema | | | | |
| Completed | 4 | 850 | Europe | SoC therapy, irbesartan, ramipril, hydrochlorothiazide, furosemide, amlodipine, atenolol, doxazosin, clonidine, insulin, simvastatin, fibrate, erythropoietin, aspirin | University of Campania "Luigi Vanvitelli" | Diabetic Nephropathy | 12/11 | 05/19 | | |
NCT01156220: Investigation of Gender Specificity of the Effects of Furosemide in Healthy Female and Male Volunteers |
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| Withdrawn | 4 | 0 | Europe | Furosemide, ATC code: C03CA01, Product name: Lasix 40 mg Injektionslösung, aminohippurate sodium, ATC code: V04CH30,, Product name: Aminohipppurate Sodium "PAH" | Universitätsklinikum Hamburg-Eppendorf | Healthy Male and Female Volunteers | 06/12 | 06/12 | | |
NCT01549158 / 2011-000972-32: Single Dose Study to Compare the Pharmacodynamics of Torasemide-PR 10 mg,Torasemide-IR 10 mg and Furosemide-IR 40 mg in Patients With Compensated Heart Failure |
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| Terminated | 4 | 8 | Europe | torasemide-PR, Furosemide-IR, torasemide-IR | Ferrer Internacional S.A. | Compensated Heart Failure | 10/12 | 12/12 | | |
| Terminated | 4 | 161 | US, Europe | High-dose furosemide, Low-dose furosemide, Low-dose furosemide combined with low-dose dopamine | Larissa University Hospital | Acute Decompensated Heart Failure | 12/13 | 12/13 | | |
| Completed | 4 | 431 | Europe | Diuretics plus human albumin, Furosemide and antialdosteronic drugs, Human albumin vials 50 cc 20% solution, Diuretics (standard medical treatment) | University of Bologna, Agenzia Italiana del Farmaco | Liver Cirrhosis, Ascites | 11/14 | 05/16 | | |
| Completed | 4 | 54 | RoW | Lasilactone, Spironolactone 100 mg plus Furosemide 20 mg, Sodium-Restricted Diet, Low sodium diet, Placebo, Placebo pill, Control | Hospital de Clinicas de Porto Alegre | Obstructive Sleep Apnea | 02/15 | 02/15 | | |
NCT01977430: Clinical Trial to Compare Effectiveness of Diuretics in Hemodialysis Patients With Residual Renal Function |
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| Unknown status | 4 | 36 | Europe | Hydrochlorothiazide and furosemide | Corporacion Parc Tauli | Chronic Kidney Insufficiency, Hemodialysis Treatment, Diuresis Preserved | 03/15 | 03/15 | | |
NCT02427880: Role of Acetazolamide and Hydrochlorothiazide Followed by Furosemide in Treating Nephrotic Edema |
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| Completed | 4 | 20 | RoW | Acetazolamide and Hydrochlorothiazide Followed by Furosemide, Diamox Sequels and Microzide Followed by Lasix, Furosemide and Hydrochlorothiazide Followed by Furosemide, Lasix and Microzide Followed by Lasix | Shiraz University of Medical Sciences | Nephrotic Syndrome, Edema | 06/15 | 06/15 | | |
2012-003815-71: The effect of furosemide on fluid volumes and biomarkers in urine for measurement of sodium and water channel activity in healthy subjects Effekten af furosemid på væskevoluminer og biomarkører i urin til måling af natrium og vandkanal aktiviteten hos raske forsøgspersoner |
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| Completed | 4 | 24 | Europe | furix, Injection, Furix 10 mg/ml | Department of Medical Research, Private and public funding | healthy people raske personer, healthy people raske personer, Body processes [G] - Physiological processes [G07] | | | | |
| Completed | 4 | 120 | RoW | FUROSEMIDE, Lasix, Placebo | Instituto Materno Infantil Prof. Fernando Figueira | Preeclampsia | 08/15 | 08/15 | | |
| Withdrawn | 4 | | US | Furosemide plus Chlorothiazide, Lasix plus Diuril, Furosemide, Lasix | Ochsner Health System | Acute Decompensated Heart Failure | 10/15 | 10/15 | | |
2008-004488-20: Ensayo clínico en fase IV, multicéntrico, controlado, aleatorizado, para evaluar la eficacia y seguridad de 3 pautas de administración de furosemida en pacientes con descompensación aguda moderada-severa de insuficiencia cardiaca crónica (Multicentric, controlled, randomized phase IV clinical trial to evaluate clinical efficacy and safety of three different dosing schedules of furosemide in patients with moderate to severe descompensation of congestive heart failure) |
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| Ongoing | 4 | 105 | Europe | Solution for injection | HOSPITAL GENERAL UNIVERSITARIO DE ALICANTE | Descompensación aguda moderada-severa en pacientes con insuficiencia cardíaca congestiva (Acute moderate to severe descompensation in patients with congestive heart failure) | | | | |
2010-024175-58: Comparison of two treatment regimen of high blood pressure in patients with transplanted heart. |
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| Ongoing | 4 | 40 | Europe | perindopril, losartan, furosemid, metoprolol, amlodipin, PRESTARIUM Neo, LORISTA 25, PRESTARIUM Neo Forte, LORISTA 50, LORISTA 100, PRESTARIUM Neo, LORISTA 25, PRESTARIUM Neo Forte, LORISTA 50, LORISTA 100 | IKEM, IKEM | Compensation of arterial hypertension in heart transplant recipients. Renal function and its changes in heart transplant recipients. | | | | |
2015-002585-23: The effect of saline with a high koncentration and furosemide on biomarkers of kidney damage togerther with kidney and circulatory physiology in healthy subjects. Effekten af saltvand med høj koncentration og furosemid på biomarkører for nyreskade samt nyre- og kredsløbsfysiologi hos raske forsøgspersoner. |
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| Ongoing | 4 | 27 | Europe | natriumklorid/sodium chloride, Infusion, Solution for infusion, Furix | Medicinsk Forskningsafsnit, Regionshospitalet Holstebro (Department of Medical Research, Regional Hospital Holstebro), Medicinsk Forskningsafsnit, Regionshospitalet Holstebro (Department of Medical Research, Regional Hospital Holstebro) | Healthy volunteers (The effect of flurosemide, together with an infusion of hypertone saline, on the kidneys, using biomarkers) Raske forsøgspersoner (ved hjælp af biomarkører ledes efter effekten af flurosemid, under infusion af hyperton natriumklorid, på nyrerne), Healthy volunteers (The effect of the diuretic flurosemide, together with an infusion of high concentration saline, on the kidneys, using biomarkers) Raske forsøgspersoner (ved hjælp af biomarkører ledes efter effekten af det vanddrivende stof flurosemid, under infusion af saltvand med høj koncentration, på nyrerne), Body processes [G] - Physiological processes [G07] | | | | |
2008-008009-23: Estudio aleatorizado, doble ciego y controlado sobre la eficacia de la albúmina y manitol en el cebado del sistema de circulación extracorpórea en cirugÃa cardiaca para reducir el sangrado postoperatorio y las necesidades transfusionalesA randomized, double-blind, controlled trial on efficacy of priming the cardiopulmonary bypass with albumin and mannitol to reduce postoperative bleeding and transfusional requirements |
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| Ongoing | 4 | 134 | Europe | human albumin, mannitol, Ringer Lactate, furosemida, human albumin, mannitol, Ringer Lactato, Seguril, human albumin, mannitol, Ringer Lactato, Seguril | Servicio de Anestesia-Reanimación | Cardiac surgery with cardiopulmonary bypass. Postoperative bleeding and requirements of blood products | | | | |
2013-001215-73: Comparative study on the bioavailability (rate and extension of absorption) between tablets of 40 mg of furosemide from two different pharmaceutical laboratories. Estudo comparativo sobre a biodisponibilidade (velocidade e extensão da absorção) entre comprimidos com 40 mg de furosemida de dois laboratórios farmacêuticos diferentes. |
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| Completed | 4 | 38 | Europe | Lasix, Furosemida Ratiopharm 40 mg Comprimidos, Lasix, Furosemida Ratiopharm 40 mg Comprimidos, Lasix, Furosemida Ratiopharm 40 mg Comprimidos | AIBILI - Associação para Investigação Biomédica e Inovação em Luz e Imagem, AIBILI - Associação para Investigação Biomédica e Inovação em Luz e Imagem | Healthy volunteers (indication: diuretic. The trial intends to assess if the reference product and a generic product are bioequivalents). Voluntários saudáveis (indicação: diurético. O estudo pretende avaliar se existe bioequivalência entre o produto de referência e um produto genérico). | | 10/13 | | |
| Completed | 4 | 123 | US | Furosemide, Lasix, Celecoxib, Celebrex, Gabapentin, Neurontin | Mayo Clinic | Colorectal Disorders | 04/16 | 04/16 | | |
NCT00904488: Oral Metolazone and Intermittent Intravenous Furosemide Versus Continuous Infusion Furosemide in Acute Heart Failure |
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| Terminated | 4 | 11 | US | Addition of oral Metolazone, Zaroxolyn, Furosemide dose escalation, Lasix | University of North Carolina, Chapel Hill, University of Illinois at Chicago, Virginia Commonwealth University | Acute Decompensated Heart Failure | 05/16 | 11/17 | | |
| Unknown status | 4 | 51 | Canada | Withdrawal of furosemide, Lasix, furosemide administration, lasix | Unity Health Toronto | End Stage Renal Disease | 12/16 | 12/16 | | |
| Completed | 4 | 170 | Europe | CA125 guided strategy, Loop diuretic (Furosemide) dosage in CA125 ≤35 U/ml patients, Loop diuretic dosage (Furosemide) in CA125 >35 U/ml patients, Conventional Strategy | Fundación para la Investigación del Hospital Clínico de Valencia | Heart Failure | 01/17 | 01/17 | | |
| Completed | 4 | 90 | US | Furosemide, Dopamine | Johns Hopkins University | Heart Failure, Diastolic | 06/17 | 05/18 | | |
| Terminated | 4 | 21 | Europe | Furosemide (Furix), Furix, Continuous renal replacement therapy (CRRT), CRRT, Resuscitation, Usual Care | Nordsjaellands Hospital, Rigshospitalet, Denmark, Aalborg University Hospital | Acute Kidney Injury, Fluid Overload, Critical Illness | 06/17 | 06/17 | | |
TORNADO, NCT01942109: The Impact of TORasemide oN hemodynAmic and Neurohormonal Stress, and carDiac remOdeling in Heart Failure |
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| Unknown status | 4 | 100 | Europe | Furosemide, Torasemide | Medical University of Warsaw | Heart Failure | 12/17 | 12/18 | | |
ResHypOT, NCT02832973: Sequential Nephron Blockade vs. Dual Blockade Renin-angiotensin System + Bisoprolol in Resistant Arterial Hypertension |
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| Completed | 4 | 72 | RoW | Spironolactone, Natriuretic diuretics, Furosemide,, Furosemide 20-40 mg, Amiloride, Amiloride 5 mg, Ramipril, ACE inhibitor, Bisoprolol, Betablocker | Sao Jose do Rio Preto Medical School | Hypertension Resistant to Conventional Therapy | 12/17 | 03/18 | | |
OUTLAST, NCT04691687: OUTpatient Intravenous LASix Trial in Reducing Hospitalization for Acute Decompensated Heart Failure |
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| Completed | 4 | 100 | NA | Furosemide, IV Furosemide, IV Solution, IV Normal Saline 0.9% | New York Presbyterian Brooklyn Methodist Hospital | Heart Failure | 12/17 | 12/17 | | |
| Completed | 4 | 33 | US | Tolvaptan, Samsca, Furosemide, Lasix | University of Southern California, Otsuka America Pharmaceutical | Heart Failure | 02/18 | 03/18 | | |
NCT02960412: Effect of Furosemide on Confirmation of Ureteral Patency During Routine Cystoscopy |
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| Completed | 4 | 150 | US | furosemide, Lasix, Normal Saline | University of South Florida | Cystoscopy | 03/18 | 06/18 | | |
| Withdrawn | 4 | 0 | US | Sodium nitroprusside, Generic name for nitropress, Dobutamine, Furosemide, Generic name for Lasix | Montefiore Medical Center | Acute Heart Failure | 05/18 | 06/18 | | |
ChiCTR2000040822: Effects of low-dose furosemide combined with aminophylline on renal function in septic shock patients |
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| Completed | 4 | 109 | | low-dose furosemide combined with aminophylline ;normal saline | Department of Critical Care Medicine, Affiliated Hospital of Guangdong Medical University; Hospital of Guangdong Medical University, National Nature Science Foundation of China | septic shock | | | | |
ChiCTR-IPR-17011846: The safety and effectiveness of tolvaptan in primary carcinoma of liver edema patients after undergoing partial hepatectomy |
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| Not yet recruiting | 4 | 60 | | tolvaptan 15mg, once daily, for 3 days ;spironolactone 100mg, furosemide 40mg, once daily, for 3 days | Tianjin First Centre Hospital; Tianjin First Centre Hospital, Zhejiang Otsuka Pharmaceutical Co., Ltd | 术后腹水 | | | | |
PROERCAN01, NCT03195023: Effect of RAS Blockers on CKD Progression in Elderly Patients With Non Proteinuric Nephropathies |
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| Recruiting | 4 | 106 | Europe | Lisinopril, Angiotensin converting enzyme inhibitors, Amlodipine, Lercanidipine, Furosemide, Thiazides | Hospital General Universitario Gregorio Marañon | Renal Insufficiency, Chronic, Proteinuria | 12/19 | 12/22 | | |
NCT03746002: Diuretic Effect of Metolazone Pre-dosing Versus Concurrent Dosing |
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| Terminated | 4 | 3 | US | Metolazone 60 minutes prior to furosemide, Zaroxolyn, Metolazone concurrently with furosemide | University of Maryland, Baltimore | Fluid Overload, Heart Failure Acute | 01/20 | 01/20 | | |
2019-004292-40: Goal directed fluid removal in critically ill patients with fluid overload. Målrettet behandling af væskeophobning hos patienter på intensiv afdeling. |
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| Ongoing | 4 | 1041 | Europe | Furosemide, Infusion | Department of Anesthesia and Intensive Care Medicine, Nordsjællands hospital, Novo Nordisk Foundation, Jakob Madsens and Hustru Olga Madsens foundation | Treatment of fluid overload in critically ill adult patients in intensive care unit., Treatment of excess fluid in the body in critically ill adults admitted to an intensive care unit., Not possible to specify | | | | |
2014-003273-42: Comparing a diuretic vascular filling in the initial management of acute pulmonary embolism with right ventricular dysfunction normotensive Comparaison d’un traitement diurétique au remplissage vasculaire dans la prise en charge initiale de l’embolie pulmonaire grave normotensive avec dysfonction ventriculaire droite |
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| Not yet recruiting | 4 | | Europe | Furosemid, NaCl 9% isotonic, 3400956401062, Injection, Furosémide, NaCl 9% isotonic | CHU de Nice, CHU de Nice | acute pulmonary embolism with right ventricular dysfunction normotensive Embolie pulmonaire grave normotensive avec dysfonction ventriculaire droite, acute pulmonary embolism with right ventricular dysfunction normotensive Embolie pulmonaire grave normotensive avec dysfonction ventriculaire droite, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
NCT02531581: Diuretic Vascular Filling in the Initial Management of Acute PE With Right Ventricular Dysfunction Normotensive |
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| Completed | 4 | 60 | Europe | Furosemide, diuretic vascular filling, NaCl 9% isotonic, fluid replacement | Centre Hospitalier Universitaire de Nice | Pulmonary Embolism | 04/20 | 04/20 | | |
| Terminated | 4 | 11 | Europe | Furosemide, furosemide stress test | Assistance Publique - Hôpitaux de Paris | Acute Kidney Injury | 12/20 | 12/20 | | |
NCT04385589: Dapagliflozin in Diabetic Patients (Type 2) With Decompensated Heart Failure |
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| Completed | 4 | 100 | RoW | Dapagliflozin, SGLT-2 inhibitors, insulin | Assiut University | Heart Failure | 12/20 | 12/20 | | |
| Recruiting | 4 | 80 | US | Furosemide, Lasix, Torsemide, Demadex, Bumetanide, Bumex, sacubitril/valsartan, Entresto, Hydralazine, Apresoline, Isosorbide Dinitrate, Dilatrate, Isordil | Heart Center Research, LLC, Boston Scientific Corporation | Heart Failure, Congestive | 12/25 | 12/26 | | |
2021-001327-41: Withdrawal of pharmacological treatment in patients responding to cardiac resynchronization therapy: Open and randomized study Retirada de tratamiento farmacologico en pacientes respondedores a terapia de resincronización cardiaca: Estudio abierto y aleatorizado |
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| Ongoing | 4 | 60 | Europe | furosemide, bisoprolol, Coated tablet, Furosemide, Bisoprolol, Eplerenone, Valsartan | Fundación para la formación e investigación sanitarias de la Región de Murcia, ISCarlos III | Heart failure Insuficiencia cardiaca, Heart failure Insuficiencia cardiaca, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
| Recruiting | 4 | 300 | Europe | Furosemide, Hydrochlorothiazide | University Hospital, Clermont-Ferrand, University Hospital, Grenoble, Hospices Civils de Lyon, Hôpital de la Croix-Rousse, CH Puy en Velay, CH Moulins-Yzeure, CH Riom, Infirmerie Protestante de Lyon, CH Issoire, CH Annecy Genevois | Heart Failure, Acute Heart Failure, Chronic Heart Failure | 12/21 | 12/21 | | |
| Terminated | 4 | 1 | US | ORKID Bundled Intervention, Furosemide | University of California, San Francisco | Acute Kidney Injury, Dialysis Hypotension | 04/22 | 04/22 | | |
ChiCTR1900022533: Evaluating the effect of different regimens of furosemide on edema in patients with nephrotic syndrome |
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| Not yet recruiting | 4 | 60 | | Furosemide, 80mg, i.v., q.d ;Furosemide, 40mg, i.v., b.i.d | the Second Affiliated Hospital of Shantou University Medical College; the Second Affiliated Hospital of Shantou University Medical College, Funding for clinical construction of the Second Affiliated Hospital of Shantou University Medical College | Nephrotic Syndrome | | | | |
NCT04343235: Postpartum Management of Gestational Hypertensive Disorders Using Furosemide |
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| Terminated | 4 | 13 | US | furosemide, lasix, labetalol, trandate | Wright State University | Hypertension, Pregnancy-Induced | 06/22 | 06/22 | | |
NCT05594823: Flexible vs. Fixed Diuretic Regimen in the Management of Chronic Heart Failure: A Pilot Study |
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| Recruiting | 4 | 30 | Canada | Ambulatory heart failure management with Flexible Diuretic Regimen with furosemide, Ambulatory heart failure management with fixed dose furosemide | Lawson Health Research Institute | Heart Failure, Heart Diseases | 07/23 | 07/23 | | |
NCT04216784: Comparison of Diuretic Effect With Furosemide Alone Versus the Combination of Furosemide and Albumin in Cirrhotic Patients |
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| Terminated | 4 | 21 | US | Furosemide Injection, Albumin Human | Rush University Medical Center | Cirrhosis, Liver, Volume Overload, Fluid Overload | 12/23 | 04/24 | | |
ChiCTR2000039724: The efficacy and safety of furosemide for prevention of intradialytic hypotension in hemodialysis patients: protocol for a multicenter randomized controlled trial |
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| Not yet recruiting | 4 | 560 | | Furosemide treatment ;Blank control | Department of Nephrology, West China Hospital of Sichuan University; West China Hospital of Sichuan University, 1·3·5 project for disciplines of excellence–Clinical Research Incubation Project, West China Hospital, Sichuan University | hemodialysis | | | | |
NCT06203236: Natriuresis-Guided Diuretic Therapy in Patients With Acute Heart Failure With Reduced Ejection Fraction and Chronic Kidney Disease |
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| Not yet recruiting | 4 | 300 | NA | Furosemide 20 MG, Lasix 20 MG, diuretic therapy | Assiut University | Acute Heart Failure, Chronic Kidney Diseases | 03/25 | 11/25 | | |
PAUSE-CRRT, NCT06229990: Protocol Based-furosemide Stress Test Versus Standard Care to Evaluate Renal Recovery During Continuous Renal Replacement Therapy |
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| Recruiting | 4 | 40 | RoW | Furosemide Injection, Furosemide stress test | Chiang Mai University | Acute Kidney Injury | 06/24 | 06/24 | | |
| Suspended | 4 | 34 | Canada | Furosemide, Chlorthalidone | University of Alberta | End Stage Renal Disease on Dialysis | 02/25 | 02/25 | | |
DAPA-TONIC, NCT06442280: SGLT-2 Inhibitor and High-Dose Furosemide Plus Small-Volume Hypertonic Saline Solution in Acute HF |
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| Not yet recruiting | 4 | 544 | NA | Dapagliflozin tablet, SGLT2 inhibitor, Hypertonic Saline Solution, 1 Ml, Hypertonic Solution, Saline, Furosemide Injection, FUROSEMIDE | University of Palermo | Heart Failure Acute, Diabetes Type 2, Heart Failure With Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction | 01/26 | 03/26 | | |
GODIF, NCT04180397: Controlled Fluid Removal in Critical Ill Patients With Fluid Overload in the Intensive Care Unit. |
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| Recruiting | 4 | 1000 | Europe, RoW | Furosemide, Furix, Isotonic saline | Morten H. Bestle, University of Copenhagen, Copenhagen Trial Unit, Center for Clinical Intervention Research, Centre for Research in Intensive Care (CRIC) | Fluid Overload | 12/24 | 06/25 | | |
| Recruiting | 4 | 46 | US | Diuretic augmentation (hydrochlorothiazide, chlorthalidone, furosemide, torsemide, or bumetanide) | VA Office of Research and Development | Chronic Kidney Disease, Hypertension | 07/25 | 07/25 | | |
| Recruiting | 4 | 75 | Europe | Furosemide, Furosemide, doubled dose, Metolazone, Furosemide + Metolazone, Acetazolamide, Furosemide + Acetazolamide | Stadtspital Zürich, Ospedale Regionale di Lugano | Acute Heart Failure, Diuretic Resistance | 08/25 | 12/25 | | |
| Recruiting | 4 | 30 | US | Furosemide (plus potassium chloride), Placebo (plus placebo electrolyte solution) | Children's Hospital Medical Center, Cincinnati, Rainbow Babies and Children's Hospital, Emory University, RTI International, National Heart, Lung, and Blood Institute (NHLBI) | Bronchopulmonary Dysplasia | 09/25 | 09/25 | | |
