| furosemide / Generic mfg. |
NCT00151827: Olmesartan Medoxomil in Hypertension and Renal Impairment |
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| Completed | 3 | 393 | Europe | Olmesartan medoxomil, Losartan, Furosemide oral tablets | Sankyo Pharma Gmbh | Essential Hypertension, Renal Impairment | 07/05 | 07/05 | | |
| Terminated | 3 | 72 | Europe | Furosemide | Medical Centre Leeuwarden | Renal Failure, Critically Ill | | 04/07 | | |
NCT00512811: Furosemide Inhalation in Dyspnea of Mustard Gas Exposed Patients |
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| Completed | 3 | | RoW | furosemide | Baqiyatallah Medical Sciences University | Bronchiolitis | | | | |
NCT00618852: Using Furosemide to Prevent Fluid Overload During Red Blood Cell Transfusion in Neonates |
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| Unknown status | 3 | 64 | Canada | Furosemide, Saline | The Hospital for Sick Children | Lung Disease | 12/08 | 06/09 | | |
| Completed | 3 | 10251 | US, Canada | Anti-hyperglycemic Agents, glimepiride (Amaryl), metformin (Glucophage), repaglinide (Gluconorm, Prandin), rosiglitazone (Avandia), pioglitazone (Actos), human regular insulin (Novolin ge Toronto), human NPH (Novolin N), human mixed (Novolin 70/30), human isophane (Novolin ge NPH), human 30/70 (Novolin ge 30/70), insulin aspart (NovoRapid, NovoLog), insulin detemir (Levemir), human regular insulin (Novolin R), insulin glargine (Lantus), Acarbose, Anti-hypertensive Agents, benazepril (Lotensin, Zestril, Altace), chlorthalidone (Thalitone), metoprolol (Toprol XL), diltiazem (Tiazac), plendil (Felodipine), terazosin (Hytrin), candesartan (Atacand), valsartan (Diovan), furosemide, reserpine, hydralazine, carvedilol (Coreg), triamterene / hydrochlorothiazide (Dyazide), metoprolol / hydrochlorothiazide(Lopressor HCT), benazepril / hydrochlorothiazide (Lotensin HCT), lisinopril / hydrochlorothiazide (Zestoretic), candesartan / hydrochlorothiazide (Atacand HCT), valsartan / hydrochlorothiazide (Diovan HCT), amlodipine / benazepril (Lotrel), Blinded fenofibrate or placebo plus simvastatin, fenofibrate (Tricor) | National Heart, Lung, and Blood Institute (NHLBI), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institute on Aging (NIA), National Eye Institute (NEI), Centers for Disease Control and Prevention | Atherosclerosis, Cardiovascular Diseases, Hypercholesterolemia, Hypertension, Diabetes Mellitus, Type 2, Diabetes Mellitus, Coronary Disease | 06/09 | 12/12 | | |
| Unknown status | 3 | 120 | Europe | Furosemide and matched saline hydration, isotonic saline solution | Centro Cardiologico Monzino | Contrast Induced Nephropathy | 06/09 | 12/09 | | |
NCT00577135: Determining Optimal Dose and Duration of Diuretic Treatment in People With Acute Heart Failure (The DOSE-AHF Study) |
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| Completed | 3 | 308 | US, Canada | Furosemide-Q12 hour bolus, Loop diuretics, Furosemide-Continuous Infusion, Loop diuretic, Furosemide-Low Intensification, Furosemide-High Intensification, loop diuretic | Duke University, National Heart, Lung, and Blood Institute (NHLBI) | Heart Failure | 01/10 | 02/10 | | |
REaCH, NCT01028170: Safety and Efficacy of Low Dose Hypertonic Saline Solution and High Dose Furosemide for Congestive Heart Failure |
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| Completed | 3 | 50 | US | furosemide and hypertonic saline solution, furosemide | Aspirus Heart and Vascular Institute-Research and Education, Aspirus Wausau Hospital | Congestive Heart Failure, Renal Insufficiency | 07/11 | 01/12 | | |
NCT00936923: Effect of Diuretics on Fluid Status Control and Residual Renal Function in Peritoneal Dialysis Patients |
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| Withdrawn | 3 | 0 | RoW | furosemide, Lasix(Diuretics) | Sun Yat-sen University | Renal Function Disorder | 12/11 | 12/12 | | |
2012-004343-80: EFFECTIVENESS OF FUROSEMIDE IN CONTINUOUS INFUSION VS ethacrynic acid IN CONTINUOUS INFUSION IN CHILDREN SUBJECT TO A heart surgery of age LESS THAN 10 YEARS Furosemide In Infusione Continua Vs Acido Etacrinico In Infusione Continua In Bambini Sottoposti A Cardiochirugia Di Eta’ Inferiore Ad 10 Anni |
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| Ongoing | 3 | 100 | Europe | Solution for infusion | OSPEDALE PEDIATRICO BAMBINO GESU' DI ROMA, Ospedale Pediatrico Bambino Gesù | ALL CHILDREN AGE 'LESS THAN 10 YEARS OF AGE' WITH CONGENITAL HEART PROCEDURE SUBJECT TO cardiac surgery in whom the diuretic ARE GIVEN IN ACCORDANCE WITH THE FOLLOWING CONTINUOUS INFUSION PROTOCOL Cardiac surgery with clamping> 90 minutes Interventions interventional cardiology with hybrid approach and inotropic score> 20 after the procedure Capillary leak syndrome postoperative and / or signs of fluid overload TUTTI I BAMBINI DI ETA’ INFERIORE A 10 ANNI DI ETA’ CON CARDIOPATIA CONGENITA SOTTOPOSTI A PROCEDURA CARDIOCHIRURGICA IN CUI IL DIURETICO SIA SOMMINISTRATO IN INFUSIONE CONTINUA SECONDO IL SEGUENTE PROTOCOLLO Interventi cardiochirurgici con clampaggio >90 minuti Interventi di cardiologia interventistica con approccio ibrido e inotropic score > 20 dopo la procedura Capillary leak syndrome postoperatoria e/o segni di sovraccarico idrico, ALL CHILDREN AGE 'LESS THAN 10 YEARS OF AGE' WITH CONGENITAL HEART PROCEDURE SUBJECT TO cardiac surgery in whom the diuretic ARE GIVEN IN ACCORDANCE WITH THE FOLLOWING CONTINUOUS INFUSION P TUTTI I BAMBINI DI ETA’ INFERIORE A 10 ANNI DI ETA’ CON CARDIOPATIA CONGENITA SOTTOPOSTI A PROCEDURA CARDIOCHIRURGICA IN CUI IL DIURETICO SIA SOMMINISTRATO IN INFUSIONE CONTINUA SECONDO IL, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
| Withdrawn | 3 | 0 | Canada | Furosemide, Lasix, Bumetanide, Bumex, Burinex, furosemide, bumetanide | Lawson Health Research Institute, University of Western Ontario, Canada | Heart Failure | 01/13 | 06/13 | | |
NCT01210365: Safety and Efficacy of Furosemide 40mg + Amiloride Hydrochloride 10mg to Reduct Edema |
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| Terminated | 3 | 27 | RoW | Diurisa®, Lasix ® | Eurofarma Laboratorios S.A. | Congestive Heart Failure | 03/13 | 03/13 | | |
NCT01628731: Furosemide Versus Ethacrynic Acid in Children With Congenital Heart Disease |
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| Completed | 3 | 74 | Europe | furosemide, lasix, ethacrynic acid, reomax | Bambino Gesù Hospital and Research Institute | Fluid Overload | 07/13 | 11/13 | | |
2013-003601-25: A multicenter, Double-blind, RandOmised, two arm Parallel group trial to determine the effects of torasemide versus furosemide on one marker (PIP) of cardiac fibrosis in patient with Diastolic Heart Failure and diabetes mellitus type II Eine multizentrische, doppelblinde, randomisierte zweiarmige Studie, die die Wirkung von Torasemid versus Furosemid auf einen Marker (PIP) der kardialen Fibrose bei Patienten mit einer diastolischen Herzinsuffizienz und Diabetes mellitus Typ II untersucht Etude DROP-PIP : une étude européenne multicentrique chez des patients ayant une insuffisance Cardiaque Diastolique et un diabète de type II. |
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| Terminated | 3 | 40 | Europe | Torasemid, Furosemid, Torasemid, Tablet, Torasemid, Furosemid | Charité Universitätsmedizin Berlin, EU Project FP7 | Diastolic heart failure and diabetes mellitus type II diastolische Herzinsuffizienz und Diabetes Typ II insuffisance cardiaque diastolique et d’un diabète de type II, Diastolic heart failure and diabetes mellitus type II, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
| Unknown status | 3 | 100 | RoW | Furosemide | Instituto Nacional de Cardiologia Ignacio Chavez | Chronic Kidney Disease | 04/16 | 04/17 | | |
FADE, NCT02055872: Furosemide and Albumin for Diuresis of Edema: A Pilot Randomized Controlled Trial |
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| Completed | 3 | 46 | Canada | Intravenous albumin, Normal saline | Hamilton Health Sciences Corporation | Edema, Hypoproteinemia | 10/16 | 10/16 | | |
| Not yet recruiting | 3 | 88 | Europe | Furosémide Renaudin, Chlorure de sodium 0,9%, Solution for injection, Solution for infusion, Furosémide Renaudin, Chlorure de sodium 0,9% | ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP), Fondation Coeur & Recherche | Myocardial infarction with right ventricular extension. Patients ayant un infarctusv inférieur avec extension au ventricule droit, NA NA, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
| Unknown status | 3 | 230 | RoW | Placebo, Furosemide | Hospital de Clinicas de Porto Alegre, Conselho Nacional de Desenvolvimento CientÃfico e Tecnológico | Heart Failure | 05/17 | 07/17 | | |
| Completed | 3 | 100 | RoW | Furosemide Injection, salbutamol inhalation | Armed Forces Hospital, Pakistan | Transient Tachypnea of the Newborn | 05/17 | 06/17 | | |
2016-003014-28: Immunosuppression in human negative virus myocarditis Immunosoppressione nella miocardite umana virus negativa |
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| Ongoing | 3 | 92 | Europe | prednisone, AZATIOPRINA, Enapren, LANOXIN, Lasix, DILATREND, [na], [NA], Tablet, Film-coated tablet, DELTACORTENE - 25 MG COMPRESSE 10 COMPRESSE, AZATIOPRINA ASPEN - 50 MG COMPRESSE RIVESTITE CON FILM 50 COMPRESSE, ENAPREN - 5 MG COMPRESSE 28 COMPRESSE, LANOXIN - 0.125 MG COMPRESSE 1 BLISTER DA 30 COMPRESSE, LASIX - 25 MG COMPRESSE30 COMPRESSE, DILATREND - 6.25 MG COMPRESSE 56 COMPRESSE | UMBERTO I - POLICLINICO DI ROMA, AIFA - Italian Medicines Agency | virus negative inflammatory cardiomyopathy cardiomiopatia infiammatoria virus negativa, Inflammation of the hearth not virus-induced Infiammazione del cuore non dovuta a virus, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
DRAIN, NCT03592836: Diuretic Response in Advanced Heart Failure: Bolus Intermittent vs Continuous INfusion |
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| Completed | 3 | 80 | Europe | Loop Diuretics, furosemide | University of Turin, Italy | Heart Failure NYHA Class III, Heart Failure NYHA Class IV | 12/17 | 12/17 | | |
| Unknown status | 3 | 270 | Europe | Diuretics : Furosemide, Placebo | Assistance Publique - Hôpitaux de Paris | Pulmonary Embolism With Right Ventricle Enlargement | 04/18 | 05/18 | | |
NCT02971891: A Phase 3 Study to Evaluate the Efficacy and Safety of CLS006 Versus Vehicle in Subjects 2 Years of Age or Older With Cutaneous Common Warts |
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| Completed | 3 | 484 | US | CLS006 (Furosemide) Topical Gel, Vehicle Topical Gel | Maruho Co., Ltd. | Cutaneous Common Warts | 04/18 | 07/18 | | |
FAMIE, NCT02905760: Efficacy of Furosemide Versus Vascular Filling in Patients With Acute Myocardial Infarction |
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| Unknown status | 3 | 88 | Europe | Furosemide, Diuretics, LASILIX., Placebo filling, G5, Placebo furosemide, Vascular filling, Fluid expansion, Sodium Chloride NaCl 0.9%. | Assistance Publique - Hôpitaux de Paris | Acute Myocardial Infarction With Right Ventricular Extension | 11/18 | 01/19 | | |
| Completed | 3 | 171 | Europe | Furosemide | Nantes University Hospital | Fluid Balance of ICU Patients, Fluid Overload | 04/19 | 04/19 | | |
NCT04628325: Effects of Furosemide Plus Small HSS in Subjects With Heart Failure With Reduced Ejection Fraction (HFrEF) |
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| Completed | 3 | 136 | Europe | Furosemide, Furosemide plus HSS | University of Palermo | Heart Failure，Congestive | 06/19 | 05/20 | | |
2019-002607-18: Clinical study on the efficacy of amiloride for the treatment of edema in nephrotic syndrome Klinische Studie über die Wirksamkeit von Amilorid zur Behandlung der Ödeme beim nephrotischen Syndrom |
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| Not yet recruiting | 3 | 36 | Europe | Furosemid-ratiopharm® 40 mgTabletten, Tablet, Modamide 5 mg tablet, Furosemid-ratiopharm® 40 mg Tabletten | University Hospital Tuebingen, Faculty of Medicine University of Tübingen | Nephrotic syndrome Nephrotisches Syndrom, Nephrotic syndrome Nephrotisches Syndrom, Diseases [C] - Symptoms and general pathology [C23] | | | | |
NCT05105009: Furosemide and Creatinine Tubular Stress Test in Order to Measure Proximal Tubule Residual Function |
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| Recruiting | 3 | 72 | RoW | Furosemide, Creatinine | Instituto Nacional de Cardiologia Ignacio Chavez | Chronic Kidney Failure | 12/21 | 07/22 | | |
NCT05270421: Effect of Furosemide on ESWL Outcomes for Renal and Ureteral Calculi |
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| Recruiting | 3 | 500 | RoW | Furosemide 40 mg, Conventional Treatment | Shiraz University of Medical Sciences | Urolithiasis, Nephrolithiasis, Urinary Calculi, Ureterolithiasis | 03/22 | 07/22 | | |
| Completed | 3 | 82 | US | Furosemide, Lasix, Placebo | Columbia University | Postpartum Pregnancy-Induced Hypertension, Postpartum Preeclampsia, Hypertension, Pregnancy-Induced, Hypertension | 04/22 | 05/22 | | |
NCT04615624: Furosemide vs. Placebo for Severe Antepartum Hypertension |
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| Completed | 3 | 65 | US | Furosemide, Placebo | Melanie Maykin, MD | Pre-Eclampsia, Hypertension in Pregnancy, Pregnancy Complications, Hypertension, Pregnancy-Induced | 04/22 | 04/22 | | |
| Completed | 3 | 2859 | US | Torsemide, Furosemide | Duke University, National Heart, Lung, and Blood Institute (NHLBI), Yale University | Heart Failure | 07/22 | 07/22 | | |
NEB-HF, NCT04465123: Early Sequential Nephron Blockade in Acute Heart Failure Patients: A Randomised, Controlled Study |
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| Recruiting | 3 | 100 | RoW | Spironolactone or hydrochlorothiazide, Aldactone, HCTZ, Thiazide, Placebo | Chiang Mai University | Acute Heart Failure, Acute Kidney Injury | 07/22 | 12/22 | | |
| Terminated | 3 | 20 | Europe | Amiloride, Furosemide | University Hospital Tuebingen | Nephrotic Syndrome, Edema, Sodium Retention | 11/22 | 11/22 | | |
NCT05620784: Intra-operative Loop Diuretics to Improve Same-day Discharge Rates After HoLEP |
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| Recruiting | 3 | 138 | US | Furosemide, Lasix, Loop diuretic | Northwestern University | BPH With Urinary Obstruction, BPH, Hematuria, Same Day Discharge | 06/23 | 08/24 | | |
TFO, NCT05093621: Torsemide Comparison With Furosemide for Management of Patients With Stable Heart Failure |
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| Active, not recruiting | 3 | 125 | US | Furosemide, Torsemide | Yale University | Heart Failure | 06/23 | 08/24 | | |
| Not yet recruiting | 3 | 200 | NA | Furosemide, Lasix, Diuretic, Normal saline | American University of Beirut Medical Center | Chronic Obstructive Pulmonary Disease Exacerbation, COPD Exacerbation | 12/24 | 12/24 | | |
NCT06407401: Improvement of Quality of Life Through Supportive Treatments for Hormone Therapy - Related Symptoms in Women With Early Breast Cancer |
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| Not yet recruiting | 3 | 399 | NA | Duloxetine 60 MG, Furosemide 40 mg, Booklet for healthy behaviors | European Organisation for Research and Treatment of Cancer - EORTC | ER+ Breast Cancer, HER2-negative Breast Cancer, Breast Cancer Stage I, Breast Cancer Stage II, Breast Cancer Stage III, Drug-Related Side Effects and Adverse Reactions, Musculoskeletal Pain | 04/28 | 11/28 | | |
FIRE Stones, NCT05916963: Impact of Forced Diuresis on the Residual Fragment Rate After Flexible Ureteroscopy for Destruction of Kidney Stones With Laser |
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| Not yet recruiting | 3 | 374 | NA | Furosemide 40 mg | University Hospital, Tours | Kidney Stone | 03/26 | 03/26 | | |
NCT00953303: The Effects of Glucocorticoids on Mortality and Renal Function in Patients With Acute Decompensated Heart Failure |
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| Completed | 2/3 | 102 | RoW | glucocorticoid, Dexamethasone Sodium Phosphate; prednisone acetate tablets, standard care, Furosemide; torsemide; nitroglycerin; dopamine; Dobutamine | Hebei Medical University | Heart Failure | 09/11 | 01/12 | | |
| Terminated | 2/3 | 72 | Canada, RoW | Furosemide, Lasix, Normal Saline, 0.9% saline | University of Alberta, Austin Hospital, Melbourne Australia, Princess Alexandra Hospital, Brisbane, Australia | Acute Renal Failure | 07/14 | 07/14 | | |
NCT02329834: Crossover Study to Compare the Pharmacokinetics and Bioavailability of a Novel Furosemide Regimen Administered Subcutaneously vs. the Same Dose Administered Intravenously in Subjects With Chronic Heart Failure |
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| Completed | 2/3 | 23 | US | Fursemide Injection Solution for subcutaneous administration (80 mg), Furosemide Injection, USP | scPharmaceuticals, Inc. | Heart Failure | 10/15 | 10/15 | | |
NCT02173288: Role of Midodrine and Tolvaptan in Patients With Cirrhosis With Refractory or Recurrent Ascites |
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| Completed | 2/3 | 50 | RoW | Standard medical therapy, Standard Medical therapy (n-15) with100 to 400mg spironolactone and/or 40 to 160mg furosemide., Tolvaptan, Tolvaptan 15 mg twice a day, Midodrine, Midodrine 7.5 mg thrice a day | Postgraduate Institute of Medical Education and Research | Cirrhosis, Refractory/Recurrent Ascites | 03/16 | 03/16 | | |
| Terminated | 2/3 | 40 | Canada | Nebulized Furosemide, Nebulized Saline | Dr. John Muscedere, University Health Network, Toronto | Covid19, Respiratory Failure | 02/23 | 04/23 | | |
NCT05933642: Diuretic Efficacy of Aminophylline and Furosemide Combination vs Furosemide Alone in Critically Ill Adults |
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| Recruiting | 2/3 | 132 | RoW | Aminophylline, Frusemide, Lasix | University of Malaya | Acute Kidney Injury | 12/23 | 12/23 | | |
INFURO, NCT06252454: The Impact of Inhaled Furosemide and Perorally Administered Levodropropizine on Dyspnea in Patients With Respiratory Diseases |
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| Recruiting | 2/3 | 102 | RoW | Furosemide 40 mg, Levodropropizine, Levopront, Placebo - saline | University Hospital Hradec Kralove, Masaryk University | Dyspnea | 12/24 | 12/25 | | |
