| furosemide / Generic mfg. |
NCT00671424: A Study To Compare Effects Of GSK189075 In Combination With Either Furosemide Or Hydrochlorothiazide |
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| Completed | 1 | 48 | US | Hydrochlorothiazide (HCTZ), Remogliflozin etabonate (GSK189075), Furosemide | GlaxoSmithKline | Type 2 Diabetes Mellitus, Diabetes Mellitus, Type 2 | 05/08 | 05/08 | | |
NCT00909519: Effect of Repeated Dosing of Naproxcinod on Renal Hemodynamic and on Sodium Balance in Healthy Volunteers Before and After a Single Dose of Furosemide |
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| Completed | 1 | 31 | Europe | naproxcinod, Naproxen, placebo, furosemide | NicOx | Renal Hemodynamics | 04/09 | 04/09 | | |
| Completed | 1 | 30 | US | furosemide, Na supplements | Yale University | Schizophrenia | 03/11 | 03/12 | | |
NCT01438359: A Drug-Drug Interaction Study of Furosemide and PA21 |
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| Completed | 1 | 42 | US | PA21 and Furosemide with food, No PA21; Furosemide with food, PA21 with food and Furosemide 2hrs later | Vifor Pharma | Healthy | 09/11 | 09/11 | | |
NCT01611415: Drug to Drug Interaction Study With Ipragliflozin and Furosemide |
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| Completed | 1 | 24 | Europe | Ipragliflozin, ASP1941, Furosemide | Astellas Pharma Europe B.V. | Healthy Subjects, Pharmacokinetics of Ipragliflozin | 10/11 | 10/11 | | |
ChiCTR-TRC-12002146: Whether the loop diuretic could cause or worse nephrotic syndrome to get acute tubular injury? |
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| Completed | 1 | 60 | | Given furosemide treatment ;Not given furosemide treatment | the Affiliated Hospital of Guangdong Medical College; Level of the institution：, Self support | nephrotic syndrome | | | | |
NCT01724788: Pharmacokinetic Profile and Pharmacodynamic Characteristics of a Furosemide High Dosage Formulation in Patients With Chronic Renal Failure Undergoing Peritoneal Dialysis |
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| Completed | 1 | 12 | Canada | FUROSEMIDE, Furosemide Special Injection, FUROSEMIDE (HOE058), Lasix® Special | Sanofi | Renal Failure | 01/13 | 01/13 | | |
NCT01887379: Magnetic Marker Monitoring of Furosemide-containing Gastroretentive Formulation in Healthy Male Subjects (Fasting and Fed Conditions) |
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| Completed | 1 | 10 | Europe | GRDF furosemide, GRDF furosemide is a gastro retentive dosage form of furesomide | LTS Lohmann Therapie-Systeme AG | Gastroretentive Drug Formulation of Furosemide, Oedema | 08/13 | 08/13 | | |
NCT02028689: Metformin and Furosemide Drug-Drug Interaction Study |
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| Completed | 1 | 23 | US | Lesinurad 400 mg, Metformin 850 mg, Furosemide 40 mg | Ardea Biosciences, Inc. | Healthy | 11/13 | 01/14 | | |
MELA, NCT02570581: Study - Hedonic Study on the Taste of Drugs Crushed in Food: Observational Study Involving 16 Healthy Volunteers |
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| Completed | 1 | 16 | Europe | Jelly with:Paracetamol, Jelly with Furosemide, Jelly with Levothyroxine sodium salt, Jelly with Memantine, Jelly with Zopiclone, Jelly with Alprazolam, Jelly with Oxazepam, Jelly with Donepezil, Jelly with Clopidogrel, Jelly with Ramipril, Jelly with Paracetamol + Furosemide + Levothyroxine sodium salt + Memantine + Zopiclone + Alprazolam, Plain jelly control, Apple compote Paracetamol, Apple compote Furosemide, Apple compote Levothyroxine sodium salt, Apple compote Memantine, Apple compote Zopiclone, Apple compote Alprazolam, Apple compote Oxazepam, Apple compote Donepezil, Apple compote Clopidogrel, Apple compote Ramipril, Apple compote + Paracetamol + Furosemide + Levothyroxine sodium salt + Memantine + Zopiclone + Alprazolam, Plain apple compote control | Centre Hospitalier Universitaire de Nice | Healthy | 07/14 | 07/14 | | |
NCT01558674: A Study of MK-7145 in Participants With Renal Insufficiency (Part I) and Heart Failure With Renal Insufficiency (Part II) (MK-7145-011) |
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| Terminated | 1 | 11 | NA | MK-7145, Furosemide, Lasix, Torsemide | Merck Sharp & Dohme LLC | Renal Impairment, Heart Failure | 12/14 | 12/14 | | |
NCT02231931: Drug-drug Interaction Between Digoxin, Furosemide, Metformin, and Rosuvastatin |
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| Completed | 1 | 24 | Europe | Digoxin, Rosuvastatin, Digoxin, Furosemide, Metformin hydrochloride, Rosuvastatin, Metformin hydrochloride, Furosemide | Boehringer Ingelheim | Healthy | 01/15 | 01/15 | | |
| | 1 | 2000 | Europe | ketamine, epinephrine, pravastatin, Furosemide, ondansetron, granisetron, clonidine, fentanyl, midazolam, oseltamivir, vasopressin, norepinephrine, milrinone, dopamine, ceftazidime, rifampin, Injection, Solution for injection, Tablet, Oral solution, Concentrate for solution for injection, Oral suspension, Capsule, Powder for oral suspension, Ketamine, Epinephrine, pravastatin, furosemide, Furosemide, ondansetron, granisetron, clonidine, fentanyl, midazolam, oseltamivir, vasopressin, norepinephrine, milrinone, dopamine, cedftazidime, rifampin | University Hospital Southampton NHS Foundation Trust | | | | | |
NCT02574845: DDI (Effect of Metformin and Furosemide on Rosuvastatin PK) |
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| Completed | 1 | 18 | Europe | Rosuvastatin, Metformin HCl, Furosemide | Boehringer Ingelheim | Healthy | 12/15 | 12/15 | | |
| Completed | 1 | 16 | Europe | Furosemide, Lasix, Saline, 0.9% sodium chloride | Oxford Brookes University | Dyspnea | 03/16 | 03/16 | | |
| Completed | 1 | 30 | Europe | Digoxin, Furosemide, Metformin, Rosuvastatin, Metformin hydrochloride | Boehringer Ingelheim | Healthy | 11/16 | 11/16 | | |
NCT02802696: Transfusion-Associated Circulatory Overload Best Eliminated With Lasix |
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| Completed | 1 | 80 | Canada | Furosemide, Lasix, Normal Saline, 0.9% Sodium Chloride | Sunnybrook Health Sciences Centre, University Health Network, Toronto, Canadian Blood Services | Transfusion-associated Circulatory Overload | 03/17 | 04/17 | | |
NCT01851980: Inhaled Nebulized Furosemide & Physical Activity-Related Breathlessness |
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| Unknown status | 1 | 30 | Canada | CWS, Chest wall strapping, Furosemide, Placebo | McGill University | Breathlessness | 04/17 | 09/17 | | |
NCT03010475: A Trial Investigating the Effect of Oral Semaglutide on the Pharmacokinetics of Furosemide and Rosuvastatin in Healthy Subjects |
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| Completed | 1 | 41 | Europe | Furosemide, Rosuvastatin, SNAC, Semaglutide | Novo Nordisk A/S | Diabetes, Healthy | 06/17 | 08/17 | | |
NCT03103568: A Study to Investigate the Potential Influence of Nitisinone on the Metabolism and the Transport of Other Drugs in Healthy Volunteers |
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| Completed | 1 | 36 | Europe | Nitisinone in Arm A, Orfadin, Tolbutamide, Metoprolol, Chlorzoxazone, Furosemide, Nitisinone in Arm B | Swedish Orphan Biovitrum, Parexel | Drug Drug Interaction | 06/17 | 07/17 | | |
| Completed | 1 | 40 | US | Furosemide, Lasix | Adrian Hernandez | Acute Heart Failure | 11/17 | 11/17 | | |
NCT03307252: This Study Tests the Effect of Certain Medicines on the Transport of Other Medicines in the Body of Healthy Men |
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| Completed | 1 | 45 | Europe | Digoxin, Furosemide, Metformin, Rosuvastatin, Verapamil, Rifampin, Cimetidine, Probenecid | Boehringer Ingelheim | Healthy | 05/18 | 05/18 | | |
NCT03801759: Drug-Drug Interaction Study of Vadadustat With Digoxin, Adefovir and Furosemide |
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| Completed | 1 | 62 | Canada | Vadadustat, AKB 6548, Furosemide, Adefovir, Digoxin | Akebia Therapeutics | Drug Interaction Potentiation | 09/18 | 09/18 | | |
NCT03772262: Assessing Goldenseal-drug Interactions Using a Probe Drug Cocktail Approach |
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| Completed | 1 | 16 | US | goldenseal, Metformin, Furosemide, Midazolam oral solution, Rosuvastatin Oral Tablet | Washington State University, National Center for Complementary and Integrative Health (NCCIH) | Interaction Drug Food | 11/18 | 03/19 | | |
NCT04481789: Clinical Pharmacology Study of Oral Edaravone in Healthy Adult Males (Drug Interaction Study and Preliminary Regimen-Finding Study) |
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| Completed | 1 | 84 | Japan | MT-1186, Edaravone, Rosuvastatin, Crestor, Sildenafil, Viagra, Furosemide, Lasix | Mitsubishi Tanabe Pharma Corporation | Healthy Adult Subjects | 12/18 | 01/19 | | |
| Completed | 1 | 14 | US | Tolvaptan 30 mg + IV Diuretics, Tolvaptan (Samsca) and Lasix (Furosemide), Metolazone 5 mg + IV Diuretics, Metolazone (Zaroxolyn) and Lasix (Furosemide), 2.5 times the Diuretics Dose, Lasix (Furosemide) | Emory University | Cardiomyopathy, Congestive Heart Failure | 12/18 | 12/18 | | |
NCT03093090: Evaluating Predictive Methods & Product Performance in Healthy Adults for Pediatric Patients, A Case Study: Furosemide |
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| Withdrawn | 1 | 0 | US | Water, Parmalat™ Whole Milk, Milk, Similac Pro-Advance™, baby formula, Ensure Plus™, Ensure, Furosemide 20 MG, Lasix | Yale University | Medication Absorption | 06/19 | 06/19 | | |
ERES-HFpEF, NCT03837470: Evaluation of Renal Sodium Excretion After Salt Loading in Heart Failure With Preserved Ejection Fraction |
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| Completed | 1 | 14 | US | 0.9% Sodium Chloride, normal saline, Furosemide 40 mg | Adhish Agarwal, University of Utah Center for Clinical and Translational Science | Heart Failure With Preserved Ejection Fraction | 02/20 | 02/20 | | |
NCT04161482: An Open Label Study to Evaluate the Impact of Duration of Subcutaneous Infusion of a Novel, pH Neutral Formulation of Furosemide (Furoscix®) on Safety and Local Skin Tolerability |
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| Completed | 1 | 39 | US | Furosemide 80 mg (8 mg/mL) | scPharmaceuticals, Inc., Clinical Trial Data Services, Inc., CSSi Life Sciences | Healthy | 06/20 | 06/20 | | |
NCT04590937: A Study in Healthy People to Test Whether BI 730357 Affects How 4 Other Medicines (Rosuvastatin, Digoxin, Metformin, and Furosemide) Are Taken up in the Body |
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| Completed | 1 | 15 | Europe | BI 730357, CRESTOR®, Rosuvastatin, Lenoxin®, Digoxin, MetfoLiquid GeriaSan®, Metformin hydrochloride, Lasix®, Furosemide | Boehringer Ingelheim | Healthy | 01/21 | 01/21 | | |
NCT04850638: Drug Interaction Between SHR4640 Tablets and Furosemide Tablets in Healthy Volunteers (Single Center, Single Arm, Open, Self-control) |
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| Completed | 1 | 18 | RoW | SHR4640 tablets and furosemide tablets | Jiangsu HengRui Medicine Co., Ltd. | Healthy Male Subjects | 09/21 | 09/21 | | |
NCT04763226: A Study to Evaluate the Safety, Tolerability, Drug Levels, and Drug Effects of BMS-986308 in Healthy Participants |
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| Completed | 1 | 46 | US | BMS-986308, Placebo (for BMS-986308), Furosemide | Bristol-Myers Squibb | Healthy Participants | 02/22 | 02/22 | | |
NCT03509545: Comparison of Once Daily 40 mg Torsemide With Twice-daily 40 mg Furosemide |
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| Completed | 1 | 20 | RoW | CHF Patients: ER Torsemide 40 mg, Demadex, CHF Patients: Furosemide 40 mg, Lasix | Sarfez Pharmaceuticals, Inc. | Body Weight Changes | 06/22 | 06/22 | | |
NCT05768360: A Study to Assess the Effects of Savolitinib on the Pharmacokinetics of Digoxin, Rosuvastatin, Metformin, and Furosemide in Healthy Male Subjects |
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| Completed | 1 | 6 | Europe | Savolitinib, Digoxin, Metformin Hydrochloride, Rosuvastatin, Furosemide | AstraZeneca, Parexel | Healthy Male Subjects | 06/23 | 06/23 | | |
NCT05365451: Pharmacokinetic Drug-Drug Interaction Study to Identify Biomarkers of Kidney Transporters |
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| Completed | 1 | 32 | US | MetFORMIN Oral Solution, Riomet, Cimetidine 400 MG, Tagamet, Furosemide Oral Liquid Product, Lasix, Probenecid 500 MG, Probalan | Washington State University, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH) | Interaction, Endogenous Biomarkers | 07/23 | 07/23 | | |
NCT05981365: Voxelotor CYP and Transporter Cocktail Interaction Study |
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| Completed | 1 | 44 | US | Voxelotor, Oxbryta, Bupropion, Wellbutrin, Repaglinide, Prandin, Flurbiprofen, Ansaid, Omeprazole, Prilosec, Midazolam, Dormicum, Metformin, Glucophage, Furosemide, Lasix, Rosuvastatin, Crestor | Pfizer | Sickle Cell Disease | 10/23 | 10/23 | | |
NCT06105255: A Study to Evaluate the Effects of D-1553 on PK of Midazolam, Caffeine, Rosuvastatin, Furosemide, Digoxin, and Itraconazole or Omeprazole on PK of D-1553 |
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| Active, not recruiting | 1 | 44 | RoW | D-1553, other | InventisBio Co., Ltd | Healthy Male | 03/24 | 07/24 | | |
NCT05098366: Furosemide Use to Fill the Bladder of Pediatric Females Awaiting Pelvic Ultrasound |
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| Completed | 1 | 42 | US | Furosemide, Lasix, Normal saline, Intravenous fluids, IV fluids | Connecticut Children's Medical Center | Ovarian Torsion | 12/23 | 12/23 | | |
NCT06167707: Pharmacokinetics and Pharmacodynamics of Subcutaneous vs Intravenous Furosemide in Healthy Volunteers |
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| Completed | 1 | 21 | US | SCP-111, Furosemide USP | scPharmaceuticals, Inc. | Heart Failure, Fluid Overload | 06/24 | 06/24 | | |
NCT05470283: Phase I, Open-Label, Study of Tumor Infiltrating Lymphocytes Engineered With Membrane Bound IL15 Plus Acetazolamide in Adult Patients With Metastatic Melanoma |
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| Active, not recruiting | 1 | 21 | US | OBX-115, Acetazolamide, Cyclophosphamide, Cytoxan®, Neosar, Furosemide, Mesna, Fludarabine Phosphate, Fludarabine, Fludara | M.D. Anderson Cancer Center | Tumor, Metastatic Melanoma, Melanoma | 04/27 | 04/27 | | |
