Xiaflex (collagenase clostridium histolyticum) / Asahi Kasei, SOBI, Endo |
| Completed | N/A | 645 | US, Europe, RoW | | Endo Pharmaceuticals | Dupuytren's Disease | 05/13 | 05/13 | | |
| Completed | N/A | 20 | US | | Theresa Bass-Goldman, Endo Pharmaceuticals | Dupuytren's Contractures | 11/14 | 12/14 | | |
NCT01876498: Registry of Patient With M. Dupuytren and Validation of the Brief MHQ |
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| Completed | N/A | 60 | Europe | Xiaflex surgery | Schulthess Klinik | Dupuytren Contracture, Collagen Shrinkage, CRF | 07/15 | 07/15 | | |
| Completed | N/A | 305 | Europe | Xiapex, surgery | Endo Pharmaceuticals | Dupuytren's Contracture | 11/15 | 11/15 | | |
NCT01446432: Validation of Two New Questionnaires for Dupuytren's Disease |
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| Unknown status | N/A | 80 | US | | Robert Hotchkiss, Auxilium Pharmaceuticals, Inc. | Dupuytren's Disease | 12/15 | 12/15 | | |
NCT01538017: Injectable Collagenase and Percutaneous Needle Fasciotomy for Dupuytren's Contracture |
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| Completed | N/A | 50 | Europe | Xiapex, XIAPEX® - Pfizer UK, Percutaneous needle fasciotomy | Jeppe Lange, MD | Dupuytrens Contracture | 10/16 | 10/16 | | |
NCT03331926: Collagenase is a Common Treatment of MCP and PIP Joint Contractures in Dupuytrens Disease |
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| Completed | N/A | 199 | NA | Xiapex | Jeppe Lange | Dupuytren Contracture | 05/17 | 12/19 | | |
NCT02301078: Short-term Function and Pain After Treatment for Dupuytren's Disease |
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| Unknown status | N/A | 60 | Canada | Percutaneous Needle Aponeurotomy, needle aponeurotomy, fasciotomy, Collagenase clostridium histolyticum, Xiaflex | Sunnybrook Health Sciences Centre | Dupuytren Disease | 10/17 | 11/17 | | |
NCT02298829 / 2014-004239-37: Long-term Safety, Curvature Deformity Characterization, and Immunogenicity Over Time in Subjects Previously Treated With AA4500 for Peyronies Disease |
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| Completed | N/A | 184 | US | Subjects Previously Treated with AA4500 | Endo Pharmaceuticals | Peyronie's Disease | 04/18 | 04/18 | | |
NCT03774264: Treatment Response to Xiaflex for Men With Peyronie's Disease |
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| Completed | N/A | 80 | US | | University of Miami, Endo Pharmaceuticals | Peyronie Disease | 07/21 | 07/21 | | |
NCT04680156: Long-term Follow-up Durability (Efficacy) Study of EN3835 for the Treatment of AC of the Shoulder (Frozen Shoulder) |
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| Terminated | N/A | 120 | US | Previously treated with EN3835 up to 1.74 mg or Placebo in EN3835-210 or the pivotal phase 3 studies | Endo Pharmaceuticals | Adhesive Capsulitis, Frozen Shoulder | 09/22 | 09/22 | | |
NCT05249257: Durability and Safety of CCH With Two Different Injection Techniques in Cellulite With Laxity |
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| Completed | N/A | 20 | US | | Endo Pharmaceuticals | Cellulite, Laxity; Skin, Edematous Fibrosclerotic Panniculopathy | 09/22 | 09/22 | | |
| Withdrawn | N/A | 800 | US | Collagenase Clostridium Histolyticum, Xiaflex, Duolith SD1 T-TOP | Mayo Clinic | Peyronie Disease, Penile Curvature, Erectile Dysfunction | 12/24 | 12/24 | | |
NCT06065436: Concurrent Low Intensity Shockwave Therapy on Collagenase Clostridium Histolyticum for Peyronie's Disease |
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| Recruiting | N/A | 60 | US | Collagenase Clostridium Histolyticum, Xiaflex, Storz Duolith LiSWT | Mayo Clinic | Peyronie Disease, Erectile Dysfunction | 12/25 | 12/25 | | |