| phenytoin / Generic mfg. |
ACTRN12614000747628: A Within-Subject Randomized Controlled Trial on the Effects of Phenytoin on Social Cognition and Behaviour in Males aged 16 Years and Older with Autism Spectrum Disorders |
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| Recruiting | 2 | 20 | | | University of Sydney, Autres PTYLD | Autism Spectrum Disorder | | | | |
NCT00040469: Bone Marrow Transplant From Related Donor for Patients With High Risk Hemoglobinopathies |
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| Terminated | 2 | 15 | US | Campath -1H, Dilantin, Busulfan, Cyclophosphamide | Baylor College of Medicine, The Methodist Hospital Research Institute, Center for Cell and Gene Therapy, Baylor College of Medicine | Sickle Cell Anemia, Hemoglobinopathy, Thalassemia | 11/03 | 11/03 | | |
VITA 2, NCT01187719: The Effect of Phenytoin on the Pharmacokinetics of Nevirapine and the Development of Nevirapine Resistance |
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| Completed | 2 | 66 | RoW | phenytoin | Radboud University Medical Center | HIV-infection, Pregnancy, Mother to Child Transmission | 06/12 | 09/12 | | |
| Completed | 2 | 42 | US | Busulfan (conditioning for AUTO transplant), Busulfex, Etoposide (conditioning for AUTO transplant), VP-16, Cyclophosphamide (conditioning for AUTO transplant), Cytoxan, Mesna (prior to AUTO transplant), autologous (auto) peripheral blood stem cell transplantation, Neupogen, G-CSF, Fludarabine (conditioning for ALLO Transplant), Fludara, Busulfan (conditioning for ALLO Transplant), non-myeloablative allogeneic (allo) transplant, Tacrolimus, FK506, Sirolimus, Rapamycin, Methotrexate | Massachusetts General Hospital, Dana-Farber Cancer Institute | Diffuse, Large B-Cell, Lymphoma, Lymphoma, Low-Grade, T-Cell Lymphoma, Mantle-Cell Lymphoma, Hodgkin's Lymphoma, Chronic Lymphocytic Leukemia, Lymphoma, Small Lymphocytic | 02/14 | 02/16 | | |
NCT02088957: Efficacy Evaluation of Intravenous Brivaracetam and Phenytoin in Subjects With Nonconvulsive Electrographic Seizures |
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| Terminated | 2 | 1 | US | Brivaracetam intravenous solution, Brivaracetam oral tablets, Phenytoin intravenous solution, Phenytoin oral tablets | UCB BIOSCIENCES, Inc., PRA Health Sciences | Nonconvulsive Electrographic Seizures | 10/14 | 10/14 | | |
| Completed | 2 | 92 | Europe | Phenytoin, Phenytoin sodium, Epanutin (Flynn Pharma), Placebo | University College, London, National Multiple Sclerosis Society, Multiple Sclerosis Society of Great Britain and Northern Ireland | Optic Neuritis, Multiple Sclerosis | 12/14 | 03/15 | | |
2004-004787-74: A double blind, prospective, randomised, controlled clinical trial to evaluate the effect of topical phenytoin, on healing, in diabetic foot ulcers. |
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| Ongoing | 2 | 144 | Europe | | Royal Group of Hospitals Trust | Diabetes Mellitus and associated diabetic foot ulceration | | | | |
2004-005046-12: A double blind prospective randomised controlled trial to evaluate the effect of topical phenytoin on the healing of venous leg ulcers |
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| Ongoing | 2 | 146 | Europe | PR1, | Ulster Community & Hospitals Trust | Venous Leg Ulceration | | | | |
2006-000487-92: A Phase II, Randomised, Double Blind, Placebo Controlled Study examining the suitability of Phenytoin Sodium Topical Gel in the treatement of Venous Ulcers |
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| | 2 | 40 | Europe | Phenytoin Sodium Gel, | Royal College of Surgeon\'s Ireland | Venous ulcers in the lower leg. | | | | |
NCT02413658: Phenytoin in the Healing of Clean Surgical Wounds |
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| Unknown status | 2 | 100 | RoW | Phenytoin, Dilantin, Dilantin-125, Sugar solution | Children's Surgical Center, Cambodia | Wound, Re-Epithelialization | 04/16 | | | |
NCT01730313: Treatment of Nodding Syndrome - A Randomized Blinded Placebo-Controlled Crossover Trial of Oral Pyridoxine and Conventional Anti-Epileptic Therapy, in Northern Uganda - 2012 |
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| Withdrawn | 2 | 0 | RoW | Pyridoxine, Vitamin B6, Sodium Valproate, Phenytoin, Placebo | Centers for Disease Control and Prevention, Ministry of Health, Uganda | Nodding Syndrome | 07/17 | 07/17 | | |
2016-001611-20: Cause-based treatment of patients with therapy resistant early onset epilepsy |
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| Ongoing | 2 | 25 | Europe | Phenytoin, Vimpat, Suspension for use in drinking water, Syrup, Vimpat Syrup | University of Tübingen, University of Tübingen | patients with epileptic encephalopathies Patienten mit epileptischen Enzephalopathien, patients with early onset diffucult to treat epilepsies Patienten mit früh beginnender schwer zu behandelnden Epilepsien, Diseases [C] - Nervous System Diseases [C10] | | | | |
NCT02939937: Effect of Phenytoin on the Ganglion Cell Layer in Patients With Optic Neuritis |
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| Completed | 2 | 71 | RoW | Phenytoin, epanutin, placebo | Tehran University of Medical Sciences | Optic Neuritis | 11/18 | 01/19 | | |
HopES, NCT03778996: SM-88 Maintenance Therapy for Advanced Ewing's Sarcoma and as Salvage Therapy for Sarcoma |
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| Active, not recruiting | 2 | 31 | US | Combination metyrosine-derivative, low-dose methoxsalen, phenytoin and sirolimus (MPS), SM-88 | Sarcoma Oncology Research Center, LLC, Tyme, Inc | Sarcoma, Ewing, Sarcoma | 12/24 | 03/25 | | |
2020-001340-25: Clinical study with phenytoin cream for the treatment of painful chronic idiopathic axonal polyneuropathy |
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| Not yet recruiting | 2 | 72 | Europe | phenytoin 10% cream, phenytoin 20% cream, Cream | University Medical Center Utrecht, Prinses Beatrix Spier Fonds | Painful chronic idiopathic axonal polyneuropathy, Peripheral nerve pain without known cause, Diseases [C] - Nervous System Diseases [C10] | | | | |
NCT05637086: Clinical Study Evaluating Safety of Pentoxifylline in Patients With Grand-Mal Epilepsy Treated by Phenytoin Monotherapy |
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| Recruiting | 2 | 60 | RoW | Phenytoin, Pentoxifylline 400 MG | Mostafa Bahaa, Sahar El-Haggar, Prof Clinical pharmacy Department- Tanta University, Principal Investigator Maha Ahmed Younis, PhD Pharmacy Practice Department- Horus University, Tarek Mohamed Mostafa, Prof Clinical pharmacy Department- Tanta University | Epilepsy | 12/26 | 11/27 | | |
NCT00245037: Busulfan, Fludarabine, and Total-Body Irradiation in Treating Patients Who Are Undergoing a Donor Stem Cell Transplant for Hematologic Cancer |
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| Completed | 1/2 | 147 | US | therapeutic allogeneic lymphocytes, busulfan, cyclosporine, fludarabine phosphate, mycophenolate mofetil, peripheral blood stem cell transplantation, Total Body Irradiation (TBI), Granulocyte colony-stimulating factor (G-CSF), Phenytoin, Methotrexate | OHSU Knight Cancer Institute, National Cancer Institute (NCI) | Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms, Precancerous Condition | 08/15 | 08/15 | | |
