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| Completed | 4 | 100 | Europe | Lacosamide, Vimpat® | UCB Pharma | Partial Epilepsies | 12/11 | 12/11 | | |
| Completed | 4 | 40 | US | Lacosamide, Vimpat | Le Bonheur Children's Hospital | Epilepsy | 05/12 | 11/12 | | |
NCT00955357 / 2009-011181-28: Trial to Assess Lacosamide as the First add-on Anti-epileptic Drug Treatment in Patients With Partial-onset Seizures |
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| Completed | 4 | 461 | US, Europe, RoW | Lacosamide, SPM927, Harkoseride, Vimpat | UCB Pharma | Partial Epilepsies | 04/13 | 08/13 | | |
2013-001834-16: EVALUATION OF SEIZURE CONTROL AND QUALITY OF LIFE IN PATIENTS WITH BRAIN TUMOR RELATED EPILEPSY TREATED WITH LACOSAMIDE AS ADD-ON THERAPY: A PROSPECTIVE EXPLORATIVE STUDY VALUTAZIONE DEL CONTROLLO DELLE CRISI E DELLA QUALITA’ DI VITA IN PAZIENTI AFFETTI DA EPILESSIA SECONDARIA A NEOPLASIA CEREBRALE IN TRATTAMENTO CON LACOSAMIDE (Vimpat®) IN ADD-ON : STUDIO PROSPETTICO ESPLORATIVO |
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| Ongoing | 4 | 40 | Europe | Tablet, VIMPAT | ISTITUTI FISIOTERAPICI OSPITALIERI, UCB Pharma | PATIENTS WITH BRAIN TUMOR RELATED EPILEPSY PAZIENTI CON EPILESSIA SECONDARIA A NEOPLASIA CEREBRALE, PATIENTS WITH BRAIN TUMOR RELATED EPILEPSY PAZIENTI CON EPILESSIA SECONDARIA A NEOPLASIA CEREBRALE, Diseases [C] - Nervous System Diseases [C10] | | | | |
NCT01190098: Randomized Controlled Trial to Assess Effects of Lacosamide on Sleep and Wake in Adults With Focal Epilepsy |
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| Completed | 4 | 59 | US | Lacosamide, LCM, Placebo, Control | The Cleveland Clinic, UCB Pharma | Partial Epilepsy | 11/14 | 11/14 | | |
NCT02409433: Comparative Trial of IV Lacosamide Versus Phenytoin for Seizure Management |
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| Terminated | 4 | 3 | Canada | lacosamide, Vimpat, Phenytoin, Dilantin | Lawson Health Research Institute, UCB Pharma GmbH | Seizures | 11/15 | 11/15 | | |
| Completed | 4 | 32 | US | Lacosamide, Vimpat | Evan Fertig, UCB Pharma | Epilepsy | 12/15 | 12/15 | | |
NCT03607851: Efficacy and Safety of Rapid Titration Protocols of Lacosamide |
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| Completed | 4 | 75 | RoW | Lacosamide - conventional titration, Lacosamide - rapid titration 1, Lacosamide - rapid titration 2 | Seoul National University Hospital, Dongsan Medical Center, Konkuk University | Focal Epilepsy | 06/19 | 06/19 | | |
NCT04144218: Evaluation of the Efficacy and Safety of Lacosamide in Pediatric Patients With Epilepsy |
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| Unknown status | 4 | 300 | RoW | Lacosamide, Placebo oral tablet | Second Affiliated Hospital, School of Medicine, Zhejiang University, Tongji Hospital, Michigan State University, Juntendo University, Technische Universität München, RIKEN, University of California, Los Angeles | Epilepsy | 10/21 | 12/21 | | |
ChiCTR1900024507: The effectiveness and safety of Lacosamide added to monotherapy in children (>=4 years and <=16 years) with epilepsy with partial-onset seizures: a multicenter real-world study |
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| Not yet recruiting | 4 | 200 | | lacosamide | West China Second Hospital, Sichuan University; West China Second Hospital, Sichuan University, Sichuan Science and Technology Department (2018SZ0123) | epilepsy | | | | |
ChiCTR2100046564: Efficacy and safety of lacosamide in children with epilepsy under 16 years of age |
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| Not yet recruiting | 4 | 100 | | Nil ;Nil | Children's Hospital of Chongqing Medical University; Children's Hospital of Chongqing Medical University, Self-funded | epilepsy | | | | |
ChiCTR2100051666: Safety and efficacy of lacosamide in the treatment of refractory focal epilepsy |
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| Not yet recruiting | 4 | 50 | | lacosamide ;AED drugs | West China Hospital of Sichuan University; West China Hospital of Sichuan University, Project of Sichuan Provincial Department of science and technology | epilepsy | | | | |
ChiCTR2100042485: A real world study on the efficacy and safety of lacosamide as add-on therapy for focal-onset epilepsy |
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| Recruiting | 4 | 200 | | lacosamide ;lacosamide | West China Hospital of Sichuan University; Jiangxi Qingfeng Pharmaceutical Co., Ltd., Jiangxi Qingfeng Pharmaceutical Co., Ltd. | Epilepsy | | | | |
2022-001603-40: Influence of pregabalin and lacosamide on the respiratory depression caused by oxycodone |
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| Ongoing | 4 | 24 | Europe | Oxycodone, Lacosamide, Pregabalin, RVG 106669, N03AX18, N03AX16, Tablet, Film-coated tablet, Capsule, hard, Oxycodone, Vimpat, Lyrica | Leiden University Medical Center, Leiden University Medical Center | Healthy Volunteers, Healthy volunteers, Body processes [G] - Physiological processes [G07] | | | | |
NCT05510856: Comparative Clinical Study Evaluating the Possible Efficacy of Duloxetine, Gabapentin and Lacosamide on Oxaliplatin-Induced Peripheral Neuropathy in Cancer Patients |
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| Recruiting | 4 | 90 | RoW | Duloxetine, Gabapentin, Lacosamide | Tanta University | Oncology | 09/23 | 09/24 | | |
POLO, NCT05598905: Combined Effect of Pregabalin and Oxycodone, and Lacosamide and Oxycodone, on Breathing |
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| Completed | 4 | 24 | Europe | Pregabalin 150mg, Lyrica capsule 150 mg, Oxycodone 10mg, Oxycodone tablet 10 mg, Lacosamide 150 mg, Vimpat 150 mg capsule | Leiden University Medical Center | Opioid-induced Respiratory Depression | 01/24 | 01/24 | | |
NCT06081283: Antiseizure Medication in Seizure Networks at Early Acute Brain Injury |
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| Recruiting | 4 | 54 | US | Phenobarbital Sodium Injection, phenobarbital, Levetiracetam, Lacosamide Injectable Product, Valproate Sodium, Valproate, Phosphenytoin | University of North Carolina, Chapel Hill | Brain Injuries, Acute, Brain Injuries, Traumatic, Brain Ischemia, Brain Hypoxia, Hypoxia-Ischemia, Brain, Heart Arrest, Stroke, Intracranial Hemorrhages, Coma, Persistent Vegetative State | 11/24 | 02/25 | | |
ChiCTR2300075071: Effectiveness of lacosamide in the treatment of pediatric patients with focal epilepsy combined with ADHD: a single center Prospective cohort study |
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| Not yet recruiting | 4 | 150 | | NA | Shengjing Hospital of China Medical University; Shengjing Hospital of China Medical University, Independently | Epilepsy | | | | |
NCT05969054: Improvement Effect of Lacosamide and Levetiracetam on Cognitive in Alzheimer's Disease Patients With Epilepsy |
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| Recruiting | 4 | 140 | RoW | Lacosamide 100 mg, Levetiracetam 250mg | Xiangya Hospital of Central South University | Alzheimer Disease 3, Epilepsy | 12/25 | 12/25 | | |
