lacosamide / Generic mfg. 
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35 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
lacosamide / Generic mfg.
2013-001834-16: EVALUATION OF SEIZURE CONTROL AND QUALITY OF LIFE IN PATIENTS WITH BRAIN TUMOR RELATED EPILEPSY TREATED WITH LACOSAMIDE AS ADD-ON THERAPY: A PROSPECTIVE EXPLORATIVE STUDY VALUTAZIONE DEL CONTROLLO DELLE CRISI E DELLA QUALITA’ DI VITA IN PAZIENTI AFFETTI DA EPILESSIA SECONDARIA A NEOPLASIA CEREBRALE IN TRATTAMENTO CON LACOSAMIDE (Vimpat®) IN ADD-ON : STUDIO PROSPETTICO ESPLORATIVO

Ongoing
4
40
Europe
Tablet, VIMPAT
ISTITUTI FISIOTERAPICI OSPITALIERI, UCB Pharma
PATIENTS WITH BRAIN TUMOR RELATED EPILEPSY PAZIENTI CON EPILESSIA SECONDARIA A NEOPLASIA CEREBRALE, PATIENTS WITH BRAIN TUMOR RELATED EPILEPSY PAZIENTI CON EPILESSIA SECONDARIA A NEOPLASIA CEREBRALE, Diseases [C] - Nervous System Diseases [C10]
 
 
ChiCTR1900024507: The effectiveness and safety of Lacosamide added to monotherapy in children (>=4 years and <=16 years) with epilepsy with partial-onset seizures: a multicenter real-world study

Not yet recruiting
4
200
 
lacosamide
West China Second Hospital, Sichuan University; West China Second Hospital, Sichuan University, Sichuan Science and Technology Department (2018SZ0123)
epilepsy
 
 
ChiCTR2100046564: Efficacy and safety of lacosamide in children with epilepsy under 16 years of age

Not yet recruiting
4
100
 
Nil ;Nil
Children's Hospital of Chongqing Medical University; Children's Hospital of Chongqing Medical University, Self-funded
epilepsy
 
 
ChiCTR2100051666: Safety and efficacy of lacosamide in the treatment of refractory focal epilepsy

Not yet recruiting
4
50
 
lacosamide ;AED drugs
West China Hospital of Sichuan University; West China Hospital of Sichuan University, Project of Sichuan Provincial Department of science and technology
epilepsy
 
 
ChiCTR2100042485: A real world study on the efficacy and safety of lacosamide as add-on therapy for focal-onset epilepsy

Recruiting
4
200
 
lacosamide ;lacosamide
West China Hospital of Sichuan University; Jiangxi Qingfeng Pharmaceutical Co., Ltd., Jiangxi Qingfeng Pharmaceutical Co., Ltd.
Epilepsy
 
 
2022-001603-40: Influence of pregabalin and lacosamide on the respiratory depression caused by oxycodone

Ongoing
4
24
Europe
Oxycodone, Lacosamide, Pregabalin, RVG 106669, N03AX18, N03AX16, Tablet, Film-coated tablet, Capsule, hard, Oxycodone, Vimpat, Lyrica
Leiden University Medical Center, Leiden University Medical Center
Healthy Volunteers, Healthy volunteers, Body processes [G] - Physiological processes [G07]
 
 
NCT05510856: Comparative Clinical Study Evaluating the Possible Efficacy of Duloxetine, Gabapentin and Lacosamide on Oxaliplatin-Induced Peripheral Neuropathy in Cancer Patients

Recruiting
4
90
RoW
Duloxetine, Gabapentin, Lacosamide
Tanta University
Oncology
09/23
09/24
POLO, NCT05598905: Combined Effect of Pregabalin and Oxycodone, and Lacosamide and Oxycodone, on Breathing

Completed
4
24
Europe
Pregabalin 150mg, Lyrica capsule 150 mg, Oxycodone 10mg, Oxycodone tablet 10 mg, Lacosamide 150 mg, Vimpat 150 mg capsule
Leiden University Medical Center
Opioid-induced Respiratory Depression
01/24
01/24
NCT06081283: Antiseizure Medication in Seizure Networks at Early Acute Brain Injury

Recruiting
4
54
US
Phenobarbital Sodium Injection, phenobarbital, Levetiracetam, Lacosamide Injectable Product, Valproate Sodium, Valproate, Phosphenytoin
University of North Carolina, Chapel Hill
Brain Injuries, Acute, Brain Injuries, Traumatic, Brain Ischemia, Brain Hypoxia, Hypoxia-Ischemia, Brain, Heart Arrest, Stroke, Intracranial Hemorrhages, Coma, Persistent Vegetative State
11/24
02/25
ChiCTR2300075071: Effectiveness of lacosamide in the treatment of pediatric patients with focal epilepsy combined with ADHD: a single center Prospective cohort study

Not yet recruiting
4
150
 
NA
Shengjing Hospital of China Medical University; Shengjing Hospital of China Medical University, Independently
Epilepsy
 
 
NCT05969054: Improvement Effect of Lacosamide and Levetiracetam on Cognitive in Alzheimer's Disease Patients With Epilepsy

Recruiting
4
140
RoW
Lacosamide 100 mg, Levetiracetam 250mg
Xiangya Hospital of Central South University
Alzheimer Disease 3, Epilepsy
12/25
12/25
2015-001769-14: Antiepileptic drug for the management of acute pain posthoracotomy Antiepiléptico para el manejo del dolor agudo postoracotomía

Ongoing
3
66
Europe
LACOSAMIDE, Solution for infusion in administration system, VIMPAT 10 mg/ml solution for infusion
Javier E. Morales Sarabia, Consorcio Hospital General Universitario de Valencia
Acute postoperative pain Dolor agudo postoperatorio, postoperative pain door tras intervención quirúrgica, Diseases [C] - Symptoms and general pathology [C23]
 
 
2021-003392-34: Aggressive or less aggressive treatment of persistent epileptic seizures

Ongoing
3
140
Europe
Briviracetam, e.g. Keppra, e.g. Topimax, e.g. orfiril, Vimpat, n.a. many producers, different producers, Concentrate and solvent for solution for infusion, Infusion, Tablet, Briviract, Levetiracetam, Fosfenytoin, Topriamate, Orfiril/valproic acid, Vimpat, Propofol, Midazolam
Odense Universitetshospital, In-house funding Odense University Hospital
Verfied non convulsive status epilepticus refractory to standard treatment with benzodiazepines and at least one first line drug, Persistent epileptic seizures that do not respond to standard treatment, Diseases [C] - Nervous System Diseases [C10]
 
 
VALUE, NCT02408549 / 2012-001770-29: Safety and Efficacy of Lacosamide as Additional Therapy in Patients Suffering From Epileptic Tonic-Clonic Seizures

Completed
3
239
Europe, Japan, US, RoW
Lacosamide Tablet, Vimpat, LCM, Lacosamide Oral Solution
UCB BIOSCIENCES, Inc.
Epilepsy
03/23
03/23
NCT05851781: Lacosamide Versus Propranolol in Migraine

Completed
3
600
RoW
Lacosamide tablet, Propranolol
Kafrelsheikh University
Migraine Disorders
07/23
08/23
NCT05632133: The Lacosamide's Effect on Calcitonin Gene-related Peptide in Migraine Patients

Completed
3
200
RoW
Lacosamide 50 MG Oral Tablet, Ibuprofen 400 mg, control
Kafrelsheikh University
Effect of Drug, Migraine Disorders
08/23
08/23
NCT06243692: Lacosamide Versus Topiramate in Migraine

Recruiting
3
600
RoW
Lacosamide 50 MG, group A, Topiramate 50Mg Tab, group B
Kafrelsheikh University
Migraine Disorders
02/25
02/25
NCT05291455: Lacosamide in Neonatal Status Epilepticus

Recruiting
3
60
RoW
Lacosamide, lacosa, Phenobarbital, phenobarbitone
Sherief Abd-Elsalam
Epilepsy
03/24
04/24
NCT04627285 / 2020-001478-30: A Study to Test the Long-term Use of Oral Lacosamide in Pediatric Study Participants Who Completed NCT01964560 (EP0034) or NCT00938912 (SP848) and Received Lacosamide Treatment

Active, not recruiting
3
48
Europe, RoW
Lacosamide
UCB Biopharma SRL
Epilepsy
07/25
07/25
2016-001611-20: Cause-based treatment of patients with therapy resistant early onset epilepsy

Ongoing
2
25
Europe
Phenytoin, Vimpat, Suspension for use in drinking water, Syrup, Vimpat Syrup
University of Tübingen, University of Tübingen
patients with epileptic encephalopathies Patienten mit epileptischen Enzephalopathien, patients with early onset diffucult to treat epilepsies Patienten mit früh beginnender schwer zu behandelnden Epilepsien, Diseases [C] - Nervous System Diseases [C10]
 
 
2019-000755-14: Trial in healthy subjects to investigate the effect of analgesic drug on pain processing observed by non-invasive neurophysiological measurements of human spinal cord and brainstem activity. Studio su soggetti sani volto ad indagare gli effetti di farmaci analgesici sulla elaborazione del dolore mediante misure neurofisiologiche del'attività del midollo del midollo spinale e del tronco dell'encefalo

Ongoing
2
56
Europe
pregabalin, lacosamide, tapentadol, [N03AX16], [N/A], [N02AX06], Capsule, hard, Film-coated tablet, Tablet, LYRICA - 75 MG CAPSULA RIGIDA - USO ORALE 100 CAPSULE IN BLISTER IN UNITA' SEPARABILI PERFORATO (PVC/ALU), VIMPAT - 100 MG - COMPRESSE RIVESTITE CON FILM - USO ORALE - BLISTER (PVC/PVDC/ALU) 14 COMPRESSE, PALEXIA - 50 MG COMPRESSE RIVESTITE CON FILM 10 COMPRESSE IN BLISTER PVC/PVDC/AL
UMBERTO I - POLICLINICO DI ROMA, Teva Pharmaceutical Industries LTD, Innovative Medicines Initiative 2 (IMI2) Joint Undertaking under grant agreement, Eli Lilly and Company LTD, Esteve Pharmaceuticals SA, Grünenthal GmbH
Healthy volunteers (intended indication: pain) soggetti sani (indicazione: dolore), Healthy volunteers (intended indication: pain) soggetti sani (indicazione: dolore), Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]
 
 
2020-001285-11: A Randomized, open label, Non-inferiority trial on the efficacy of Lacosamide versus Duloxetine in Patients with Chemotherapy-induced Polyneuropathy – A strategy trial

Ongoing
2
100
Europe
Duloxetine, Lacosamide, N06AX21, N03AX18, Capsule, Film-coated tablet, Cymbalta, Vimpat
Leiden University Medical Center, Leiden University Medical Center
Chemotherapy-induced polyneuropathy, Nerve pain after chemotherapy, Diseases [C] - Nervous System Diseases [C10]
 
 
2019-000942-36: The effects of lacosamide, pregabalin and tapentadol on biomarkers of peripheral pain processing

Not yet recruiting
2
60
Europe
lacosamide, Pregabalin, Tapentadol, [N02AX06], [N/A], [N03AX16], Tablet, Capsule, Vimpat 100 mg film coated tablets, Lyrica 75 mg hard capsules, Palexia 50 mg film-coated tablets
Aarhus University, UMBERTO I - POLICLINICO DI ROMA, Innovative Medicines Initiative 2 (IMI2) Joint Undertaking under grant agreement, Eli Lilly and Company LTD, Esteve Pharmaceuticals SA, Grünenthal GmbH, Teva Pharmaceutical Industries LTD
Healthy volunteers (intended indication: pain), Study in healthy volunteers to examine drug effects on biomarkers in experimental pain, Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]
 
 
NCT03777956 / 2018-003110-40: The Effect of Lacosamide in Peripheral Neuropathic Pain

Terminated
2
63
Europe
Lacosamide, Placebo
Danish Pain Research Center, Odense University Hospital
Neuropathic Pain, Neuropathy;Peripheral, Neuropathy, Painful, Neuropathy, Diabetic, Neuropathy
06/22
06/22
2019-001204-37: The effects of lacosamide, pregabalin and tapentadol on biomarkers of pain processing

Not yet recruiting
2
56
Europe
lacosamide, pregabalin, tapentadol, [N02AX06], [N03AX16], [N/A], Film-coated tablet, Capsule, Tablet, Vimpat 100mg film coated tablets, Lyrica 75 mg hard capsules, Palexia 50 mg film-coated tablets
Institute of Neuroscience (IoNS), Université catholique de Louvain, UMBERTO I - POLICLINICO DI ROMA, Innovative Medicines Initiative 2 (IMI2) Joint Undertaking under Grant Agreement, Eli Lilly and Company LTD, Esteve Pharmaceuticals SA, Grünenthal GmBH, Teva Pharmaceutical Industries LTD
Healthy subjects (intended indication: pain), Study in healthy subjects to examine drug effects on biomarkers in experimental pain, Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]
 
 
2019-000908-15: The effects of lacosamide, pregabalin and tapentadol on pain processing

Not yet recruiting
2
36
Europe
lacosamide, Pregabalin, Tapentadol, Tablet, Capsule, Vimpat 100 mg film coated tablets, Lyrica 75 mg hard capsules, Palexia 50 mg film-coated tablets
Aarhus University, Innovatice Medicines Initiative 2 (IMI2) Joint Undertaking under grant agreement, Eli Lilly and Company LTD, Esteve Pharmaceutical Industries LTD, Grünenthal GmbH, Teva Pharmaceutical Industries LTD
Healthy volunteers (intended indication: pain), Study in healthy volunteers to examine drug effects on biomarkers in experimental pain, Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]
 
 
LENS, NCT04519645 / 2020-001066-10: A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Lacosamide in Neonates With Repeated Electroencephalographic Neonatal Seizures

Recruiting
2
32
Canada, US, RoW
Lacosamide intravenous, LCM, Lacosamide oral, Active Comparator
UCB Biopharma SRL
Electroencephalographic Neonatal Seizures, Epilepsy
08/25
08/25
STTEPP, NCT05603702: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis

Recruiting
1
24
US
Lacosamide, VIMPAT
Indiana University, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Chronic Pain, Chronic Pain Syndrome, Chronic Pancreatitis, Hyperalgesia, Opioid Use Disorder, Opioid-Related Disorders, Opioid Dependence, Chronic Abdominal Pain, ERCP, Pancreatic Surgery
12/24
12/24
ACTRN12622001121752: Lacosamide pharmacokinetics changes in blood and breast mild during and after pregnancy

Recruiting
N/A
30
 
Melbourne Health trading as The Royal Melbourne Hospital, UCB BIOPHARMA SRL
Epilepsy
 
 
NCT03559673: Compassionate Use Program With Lacosamide in Patients With Partial-onset or Generalized Tonic-clonic Seizures

No Longer Available
N/A
NA
Lacosamide, Vimpat
UCB Biopharma S.P.R.L.
Epilepsies, Partial
 
 
SUPER-CAT, NCT05756621: Dual Anti-glutamate Therapy in Super-refractory Status Epilepticus After Cardiac Arrest

Recruiting
N/A
80
Europe
Ketamine, Perampanel, Any anti-epileptic and anesthetic therapy, excluding Ketamine and Perampanel, Levetiracetam, Valproate, Phenytoin, Lacosamide, Topiramate, Propofol, Midazolam, Thiopental
University of Milano Bicocca, Azienda Ospedaliera San Gerardo di Monza, Azienda Ospedaliero-Universitaria di Modena, Azienda Ospedaliera Universitaria Integrata Verona, Ospedale Centrale Bolzano, Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Azienda Ospedaliero-Universitaria Careggi, Azienda Ospedaliero-Universitaria di Parma, Santa Chiara Hospital, Ospedale M. Bufalini Cesena, Azienda Ospedaliera Brotzu, Istituto Di Ricerche Farmacologiche Mario Negri
Status Epilepticus, Cardiac Arrest
06/24
09/24
NCT05543122: Drug Concentrations in Breast Milk and Prediction of Blood Levels of the Breastfed Infants

Completed
N/A
39
Canada
either of Atenolol, Bupropion, Brivaracetam, Escitalopram, Fluconazole, Lacosamide, Lamotrigine, Levetiracetam, Methotrexate or Ezetimibe, Typical brand names include, but not limited to: Tenoretic, Wellbutrin, Zyban, Briviact, Cipralex, Lexapro, Diflucan, Vimpat, Lamictal, Keppra, Trexall, Xatmep, Ezetrol, Nexlizet
The Hospital for Sick Children, St. Justine's Hospital, University of Waterloo
Breast Feeding
12/23
03/24
NCT05422664: Acute Sympotomatic Seizure Secondary to Autoimmune Encephalitis and Autoimmune-associated Epilepsy

Enrolling by invitation
N/A
500
RoW
Lacosamide
Liu Yonghong, First Affiliated Hospital Xi'an Jiaotong University, Second Affiliated Hospital of Xi'an Jiaotong University, Xian Children's Hospital, Baoji Central Hospital, First Affiliated Hospital of Kunming Medical University, First Affiliated Hospital of Harbin Medical University, Qilu Children's Hospital of Shandong University
Autoimmune Encephalitis, Epilepsy, Seizures
05/25
12/25
EPIPOP, NCT03196466: Population Pharmacokinetics of Antiepileptic in Pediatrics

Recruiting
N/A
1000
Europe
Valproic acid, carbamazepine, phenobarbital, phenytoin, levetiracetam, lamotrigine, topiramate, oxcarbazepine, stiripentol, clobazam, brivaracétam, felbamate, lacosamide, rufinamide, gabapentine, pregabaline, sultiame, tiagabine, vigabatrine, mesuximide, primidone, perampanel, ethosuximide, zonisamide, cannabidiol, genetic polymorphisms
Assistance Publique - Hôpitaux de Paris
Epilepsy
06/26
06/26
NCT04737837: A Real World Study on the Efficacy and Safety of Lacosamide as Add-on Therapy for Focal-onset Epilepsy

Not yet recruiting
N/A
200
RoW
lacosamide, Xinkang
Jiangxi Qingfeng Pharmaceutical Co. Ltd.
Epilepsy, Focal-Onset Seizure
11/21
02/22

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