ChiCTR1900022534: Efficacy of entacapone and pramipexole for non-motor symptoms of Parkinson’s disease: a prospective randomized controlled trial |
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| Not yet recruiting | N/A | 388 | | Patients in the entacapone group will be administered entacapone (Novartis; import drug registration certificate number: H20160680), 10 times per day, 200 mg each time, for 3 weeks. ;Patients in the pramipexole group will be administered pramipexole (Boehringer-Ingelheim; import drug registration certificate number: 20140918) , 3 times per day, 1 mg each time, for 3 weeks. | Geriatric Hospital of Hainan; Geriatric Hospital of Hainan, Self-funded | non-motor symptoms of Parkinson’s disease | | | | |